准分子激光原位角膜磨镶术的研究进展

近年来,准分子激光原位角膜磨镶术以其安全、有效等特点在国内外得到广泛应用,成为眼屈光手术的主流术式。

角膜交联治疗圆锥角膜的方法及临床效果分析

角膜胶原交联手术（CXL）为治疗圆锥角膜的新式技术,其主要通过360～380nm波长A段紫外线照射感光剂核黄素生成光敏反应^（[1]）,诱导角膜基质中胶原纤维互相交联,加强角膜应力、生物化学以及力学稳定性,进而避免圆锥角膜进一步扩张。目前,CXL术已经被广泛应用在临床治疗中,且已经取得一定效果。

无汗性外胚层发育不良伴特发性角膜穿孔和圆锥角膜的病例

A patient with anhidrotic ectodermal dysplasia and severe dry eyes was admitted with spontaneous corneal perforation in his right eye. The corneal perforation was sealed with cyanoacrylate glue and bandage contact lens placement. Three weeks later, the patient underwent penetrating keratoplasty. On follow- up examination, he had corneal graft abscess that was treated successfully with topical antibiotics and corneal erosion that was treated with a bandage contact lens. Corneal topography performed as a routine examination showed inferior corneal steepening typical of keratoconus in the left eye. This accidental discovery of keratoconus in the patient’ s left eye may suggest a possible association between anhidrotic ectodermal dysplasia and keratoconus.

七叶洋地黄双苷滴眼液治疗老年2型糖尿病干眼症的疗效探究

目的:观察老年2型糖尿病干眼症应用七叶洋地黄双苷滴眼液治疗的效果。方法:回顾性分析2015年10月至2018年10月我院收治的2型糖尿病干眼症患者86例(共169只眼)。依据治疗方法不同,分为观察组(七叶洋地黄双苷滴眼液滴眼,n=43,共85只眼)与对照组(人工泪液滴眼,n=43,共84只眼)。比较两组症状评分、BUT与SIt检查结果、角膜地形图检查结果[角膜表面规则指数(SRI)、表面不对称指数(SAI)]。结果:两组治疗后症状评分均降低,且观察组低于对照组,差异有统计学意义(P<0.05);两组治疗后BUT均延长,且观察组幅度大于对照组,差异有统计学意义(P<0.05);两组治疗后SIt均延长,但两组比较,差异无统计学意义(P>0.05);两组治疗后SRI与SAI均下降,且观察组幅度大于对照组,差异有统计学意义(P<0.05)。结论:针对老年2型糖尿病干眼症患者,应用七叶洋地黄双苷滴眼液治疗较人工泪液滴眼治疗,可更为有效地加快患者症状改善,且利于提升泪膜的规则性与稳定性,对促进患者眼部健康的恢复具有重要作用,但对泪液分泌改善的效果稍弱。