To evaluate whether the visual, topographic, and endothelial cell count result s observed 1 year after deep lamellar endothelial keratoplasty (DLEK) surgery re main stable up to 2 years after surgery. Prospective, non...To evaluate whether the visual, topographic, and endothelial cell count result s observed 1 year after deep lamellar endothelial keratoplasty (DLEK) surgery re main stable up to 2 years after surgery. Prospective, noncomparative, interventi onal case series. Twenty eyes of 20 patients with corneal edema from Fuchs’endo thelial dystrophy. Deep lamellar endothelial keratoplasty endothelial replacemen t surgery, with a 9.0-mm or 9.5-mm scleral access incision and a specialized i ntrastromal trephine, was performed. Snellen visual acuities, corneal topography , and endothelial cell counts were prospectively measured preoperatively and 1 y ear and 2 years after DLEK. Uncorrected and best spectacle-corrected visual acu ity (BSCVA), refractive and topographic astigmatism, mean corneal curvature, top ographic regularity and symmetry, and endothelial cell density. At 1 year postop eratively, BSCVA averaged 20/50 (range, 20/25-20/200), spherical equivalents (S E)averaged -0.194±1.521 diopters (D), manifest refraction (MR) astigmatism ave raged 2.04±1.05 D (range, 0.0-4.0 D), topographic astigmatism averaged 2.3±1. 1 D, mean corneal curvature was 43.2±1.8 D, the surface regularity index (SRI) averaged 1.16±0.41, and the surface asymmetry index (SAI) averaged 1.05±1.09. At 2 years postoperatively, BSCVA averaged 20/48 (range, 20/25-20/200), SEavera ged-0.369±1.267 D, MR astigmatism averaged 1.76±0.66 D (range, 0.75-3.0 D), topographic astigmatism averaged 2.4±1.1 D, mean corneal curvature was 43.6±1. 8 D, the SRI averaged 1.13±0.44, and the SAI averaged 0.76±0.59. There was no significant change in visual or topographic parameters between 1 year and 2 year s postoperatively (P > 0.05). Endothelial cell counts averaged 2 335±468 cells/ mm2 at 1 year and 2 151±457 cells/mm2 at 2 years postoperatively (P=0.041). Dee p lamellar endothelial keratoplasty provides stable refractions, corneal topogra phy, and endothelial cell densities as long as 2 years after surgery. The absenc e of corneal sutures in this technique seems to prevent the sutures in/sutures o ut changes in SE refractions and corneal topography sometimes seen after penetra ting keratoplasty (PK). Deep lamellar endothelial keratoplasty is, therefore, an excellent alternative to PK for patients with endothelial dystrophies.展开更多
目的:回顾性研究近视儿童口服递法明片后6mo内近视进展情况。方法:收集2012-06/2015-01来我院就诊的3~13岁年龄段的近视患者36例69眼,其中男16例30眼,女20例39眼,双眼经阿托品散瞳验光后根据等效球镜度数分为三组,其中高度近视组(>-6...目的:回顾性研究近视儿童口服递法明片后6mo内近视进展情况。方法:收集2012-06/2015-01来我院就诊的3~13岁年龄段的近视患者36例69眼,其中男16例30眼,女20例39眼,双眼经阿托品散瞳验光后根据等效球镜度数分为三组,其中高度近视组(>-6.00D)30眼,中度近视组(-3.00^-6.00D)24眼,轻度近视组(<-3.00D)15眼;根据年龄分为两组,其中学龄前组(<6岁)21眼,青少年组(≥6岁)48眼。均口服递法明片,使用前及使用后6mo自身对比分析等效球镜度数、最佳矫正视力、眼轴长度、角膜曲率半径、并计算眼轴(axial length,AL)和平均角膜曲率半径(curvatures radius of cornea,CR)的比值(AL/CR)。结果:服用递法明片后6mo内,轻度和中度近视儿童患者的等效球镜度数、眼轴和AL/CR均较服药前有增加,但只有中度近视儿童患者有统计学意义(P<0.05);高度近视儿童患者等效球镜度数、眼轴较服药前有增加,AL/CR无明显变化,均无统计学意义(P>0.05)。学龄前组和青少年组等效球镜度数、眼轴和AL/CR均较服药前增加,但只有学龄前组眼轴和AL/CR差异有统计学意义(P<0.05)。结论:短期口服递法明对于儿童的轻度和重度近视的进展有一定的控制作用,但是对于儿童的中度近视控制作用不明显;同时短期口服对青少年近视进展控制有一定的作用,但是对学龄前儿童近视进展控制作用不明显。展开更多
文摘To evaluate whether the visual, topographic, and endothelial cell count result s observed 1 year after deep lamellar endothelial keratoplasty (DLEK) surgery re main stable up to 2 years after surgery. Prospective, noncomparative, interventi onal case series. Twenty eyes of 20 patients with corneal edema from Fuchs’endo thelial dystrophy. Deep lamellar endothelial keratoplasty endothelial replacemen t surgery, with a 9.0-mm or 9.5-mm scleral access incision and a specialized i ntrastromal trephine, was performed. Snellen visual acuities, corneal topography , and endothelial cell counts were prospectively measured preoperatively and 1 y ear and 2 years after DLEK. Uncorrected and best spectacle-corrected visual acu ity (BSCVA), refractive and topographic astigmatism, mean corneal curvature, top ographic regularity and symmetry, and endothelial cell density. At 1 year postop eratively, BSCVA averaged 20/50 (range, 20/25-20/200), spherical equivalents (S E)averaged -0.194±1.521 diopters (D), manifest refraction (MR) astigmatism ave raged 2.04±1.05 D (range, 0.0-4.0 D), topographic astigmatism averaged 2.3±1. 1 D, mean corneal curvature was 43.2±1.8 D, the surface regularity index (SRI) averaged 1.16±0.41, and the surface asymmetry index (SAI) averaged 1.05±1.09. At 2 years postoperatively, BSCVA averaged 20/48 (range, 20/25-20/200), SEavera ged-0.369±1.267 D, MR astigmatism averaged 1.76±0.66 D (range, 0.75-3.0 D), topographic astigmatism averaged 2.4±1.1 D, mean corneal curvature was 43.6±1. 8 D, the SRI averaged 1.13±0.44, and the SAI averaged 0.76±0.59. There was no significant change in visual or topographic parameters between 1 year and 2 year s postoperatively (P > 0.05). Endothelial cell counts averaged 2 335±468 cells/ mm2 at 1 year and 2 151±457 cells/mm2 at 2 years postoperatively (P=0.041). Dee p lamellar endothelial keratoplasty provides stable refractions, corneal topogra phy, and endothelial cell densities as long as 2 years after surgery. The absenc e of corneal sutures in this technique seems to prevent the sutures in/sutures o ut changes in SE refractions and corneal topography sometimes seen after penetra ting keratoplasty (PK). Deep lamellar endothelial keratoplasty is, therefore, an excellent alternative to PK for patients with endothelial dystrophies.
文摘目的:回顾性研究近视儿童口服递法明片后6mo内近视进展情况。方法:收集2012-06/2015-01来我院就诊的3~13岁年龄段的近视患者36例69眼,其中男16例30眼,女20例39眼,双眼经阿托品散瞳验光后根据等效球镜度数分为三组,其中高度近视组(>-6.00D)30眼,中度近视组(-3.00^-6.00D)24眼,轻度近视组(<-3.00D)15眼;根据年龄分为两组,其中学龄前组(<6岁)21眼,青少年组(≥6岁)48眼。均口服递法明片,使用前及使用后6mo自身对比分析等效球镜度数、最佳矫正视力、眼轴长度、角膜曲率半径、并计算眼轴(axial length,AL)和平均角膜曲率半径(curvatures radius of cornea,CR)的比值(AL/CR)。结果:服用递法明片后6mo内,轻度和中度近视儿童患者的等效球镜度数、眼轴和AL/CR均较服药前有增加,但只有中度近视儿童患者有统计学意义(P<0.05);高度近视儿童患者等效球镜度数、眼轴较服药前有增加,AL/CR无明显变化,均无统计学意义(P>0.05)。学龄前组和青少年组等效球镜度数、眼轴和AL/CR均较服药前增加,但只有学龄前组眼轴和AL/CR差异有统计学意义(P<0.05)。结论:短期口服递法明对于儿童的轻度和重度近视的进展有一定的控制作用,但是对于儿童的中度近视控制作用不明显;同时短期口服对青少年近视进展控制有一定的作用,但是对学龄前儿童近视进展控制作用不明显。
