目的:观察非球面切削准分子激光原位角膜磨镶术(1aser in situ keratomileusis,LASIK)后泪液分泌、泪膜的变化,探讨其与干眼的关系。方法:对80名近视眼患者实施双眼LASIK非球面切削手术,分别用SchirmerⅠ试验(基础分泌试验)和荧光素染...目的:观察非球面切削准分子激光原位角膜磨镶术(1aser in situ keratomileusis,LASIK)后泪液分泌、泪膜的变化,探讨其与干眼的关系。方法:对80名近视眼患者实施双眼LASIK非球面切削手术,分别用SchirmerⅠ试验(基础分泌试验)和荧光素染色测定患者术前、术后1周、1个月、3个月、6个月的泪液分泌值和泪膜破裂时间(break up time,BUT)。结果:(1)BUT值(单位:秒):术前为20.07±5.90,术后1周、1个月、3个月、6个月分别为8.47±2.64、10.51±2.63、13.29±2.74、19.85±5.75,术后1周、1个月、3个月分别与术前的BUT值比较,差异均有显著性意义(P<0.01),术后6个月BUT值与术前比较无显著性差异(P>0.05)。Schirmer值(单位:mm):术前为16.24±6.68,术后1周、1个月、3个月、6个月分别为12.86±6.14、14.65±9.92、15.38±6.27、16.18±5.77,术后1周、1个月和3个月Schirmer值分别与术前比较,差异有统计学意义(P<0.05),而术后6个月Schirmer值与术前比较差异无统计学意义(P>0.05)。结论:LASIK非球面切削术后3个月内泪膜稳定性下降及泪液分泌减少,术后6个月泪膜稳定性和泪液分泌恢复术前水平。展开更多
Objective： To report the occurrence, management and outcome ot late-onset traumauc aemscence ana dislocation of laser assisted in situ keratomileusis （LASIK） flaps. Treatment and Results： One patient occurred late...Objective： To report the occurrence, management and outcome ot late-onset traumauc aemscence ana dislocation of laser assisted in situ keratomileusis （LASIK） flaps. Treatment and Results： One patient occurred late-onset LASIK corneal flap dislocation after ocular trauma 7days after surgery. The flap was lifted, stretched, and repositioned after irrigation and scraping of the stromal bed and the underside of the flap. A bandage contact lens was placed, and topical antibiotic and corticosteroids were given postoperatively. The dislocated corneal flap was successfully repositioned in the case. The dislocated flap was repositioned 7 days after the trauma, and the patient recovered his uncorrected visual acuity （UCVA） of 10/20, 20/20 day 1 and day 20 after the procedure, of 20/20 20 days later and had a well-positioned flap with a clear interface. Diffuse lamellar keratitis developed in the patients that resolved with the use of topical corticosteroids. Conclusion： Laser in situ keratomileusis corneal flaps are vulnerable to traumatic dehiscence and dislocation, which should be pay more attention to it for us.展开更多
文摘目的:观察非球面切削准分子激光原位角膜磨镶术(1aser in situ keratomileusis,LASIK)后泪液分泌、泪膜的变化,探讨其与干眼的关系。方法:对80名近视眼患者实施双眼LASIK非球面切削手术,分别用SchirmerⅠ试验(基础分泌试验)和荧光素染色测定患者术前、术后1周、1个月、3个月、6个月的泪液分泌值和泪膜破裂时间(break up time,BUT)。结果:(1)BUT值(单位:秒):术前为20.07±5.90,术后1周、1个月、3个月、6个月分别为8.47±2.64、10.51±2.63、13.29±2.74、19.85±5.75,术后1周、1个月、3个月分别与术前的BUT值比较,差异均有显著性意义(P<0.01),术后6个月BUT值与术前比较无显著性差异(P>0.05)。Schirmer值(单位:mm):术前为16.24±6.68,术后1周、1个月、3个月、6个月分别为12.86±6.14、14.65±9.92、15.38±6.27、16.18±5.77,术后1周、1个月和3个月Schirmer值分别与术前比较,差异有统计学意义(P<0.05),而术后6个月Schirmer值与术前比较差异无统计学意义(P>0.05)。结论:LASIK非球面切削术后3个月内泪膜稳定性下降及泪液分泌减少,术后6个月泪膜稳定性和泪液分泌恢复术前水平。
文摘Objective： To report the occurrence, management and outcome ot late-onset traumauc aemscence ana dislocation of laser assisted in situ keratomileusis （LASIK） flaps. Treatment and Results： One patient occurred late-onset LASIK corneal flap dislocation after ocular trauma 7days after surgery. The flap was lifted, stretched, and repositioned after irrigation and scraping of the stromal bed and the underside of the flap. A bandage contact lens was placed, and topical antibiotic and corticosteroids were given postoperatively. The dislocated corneal flap was successfully repositioned in the case. The dislocated flap was repositioned 7 days after the trauma, and the patient recovered his uncorrected visual acuity （UCVA） of 10/20, 20/20 day 1 and day 20 after the procedure, of 20/20 20 days later and had a well-positioned flap with a clear interface. Diffuse lamellar keratitis developed in the patients that resolved with the use of topical corticosteroids. Conclusion： Laser in situ keratomileusis corneal flaps are vulnerable to traumatic dehiscence and dislocation, which should be pay more attention to it for us.
