Astrocytes have potential to break synchrony between neurons. Authors＇ recent researches reveal that astrocytes vary the synchronization threshold and provide an appropriate feedback control in stabilizing neural act...Astrocytes have potential to break synchrony between neurons. Authors＇ recent researches reveal that astrocytes vary the synchronization threshold and provide an appropriate feedback control in stabilizing neural activities. In this study, we propose an astrocyte-inspired controller for desynchronization of two coupled limit-cycle oscillators as a minimal network model. The design procedure consists of two parts. First, based on the astrocyte model, the structure of the dynamic controller is suggested. Then, to have an emcient controller, parameters of controller are tuned through an optimization algo- rithm. The proposed bio-inspired controller takes advantages of three important proper- ties： （1） the controller desynchronizes the oscillators without any undesirable effects （e.g. stopping, annihilating or starting divergent oscillations）; （2） it consumes little effort to preserve the desirable desynchronized state; and （3） the controller is robust with respect to parameters＇ variations. Simulation results reveal the ability of the proposed controller.展开更多
文摘Astrocytes have potential to break synchrony between neurons. Authors＇ recent researches reveal that astrocytes vary the synchronization threshold and provide an appropriate feedback control in stabilizing neural activities. In this study, we propose an astrocyte-inspired controller for desynchronization of two coupled limit-cycle oscillators as a minimal network model. The design procedure consists of two parts. First, based on the astrocyte model, the structure of the dynamic controller is suggested. Then, to have an emcient controller, parameters of controller are tuned through an optimization algo- rithm. The proposed bio-inspired controller takes advantages of three important proper- ties： （1） the controller desynchronizes the oscillators without any undesirable effects （e.g. stopping, annihilating or starting divergent oscillations）; （2） it consumes little effort to preserve the desirable desynchronized state; and （3） the controller is robust with respect to parameters＇ variations. Simulation results reveal the ability of the proposed controller.
