Objective:To observe the effect of electroacupuncture on learning and memory in rats with vascular dementia.Methods:Seventy-two SD rats were randomly divided into 4 groups,a normal group,a sham operation group,a mod...Objective:To observe the effect of electroacupuncture on learning and memory in rats with vascular dementia.Methods:Seventy-two SD rats were randomly divided into 4 groups,a normal group,a sham operation group,a model group and an electroacupuncture (EA) pretreatment group.Modified intraluminal embolism method with nylon thread was applied to make rat model of vascular dementia,and the ability of learning and memory was observed in Morris water maze.Results:The average time of escape and latency in the rats of model group in the water maze test was prolonged,with significant difference compared with that in the sham group (P〈0.01).The average time of escape and latency and navigation test results of rats pretreated by EA had statistically significant difference compared with those of the model group (P〈0.01).Conclusion:EA pretreatment can significantly improve the ability of learning and memory of the rats with vascular dementia.展开更多
Objective:To investigate the effects of acupoint massage on cognitive function and sleep quality in elderly patients with hypertension. Methods:A total of 68 elderly patients with hypertension were enrolled, and the...Objective:To investigate the effects of acupoint massage on cognitive function and sleep quality in elderly patients with hypertension. Methods:A total of 68 elderly patients with hypertension were enrolled, and their ages were all over 60 years old. They were divided into a control group and a treatment group by simple random method, with 34 cases in each group. Patients in the control group were treated by routine psychological health guidance and sleep knowledge education, while patients in the treatment group were treated by acupoint massage on the base of the interventions given to the control group. Both of their treatment courses were 3 months. Pittsburgh sleep quality index (PSQI) scores and mini-mental state examination (MMSE) scores before and after treatment were recorded and compared. Results:Two groups’ PSQI scores before treatment had no significant difference (P〉0.05). After 3 months of treatment, their PSQI scores were statistically different (P〈0.05). There was also no between-group statistical difference in MMSE score before treatment (P〉0.05), but there was a significant difference after treatment (P〈0.05). Conclusion:Acupoint massage for elderly patients with primary hypertension can improve their sleep quality and enhance their cognitive function, thus it is worthy of being applied in clinical nursing work.展开更多
Objective:To investigate the effectiveness and safety of manual acupuncture for memory loss and sleep quality in chronic insomniacs.Methods:A total of 60 eligible participants were enrolled and randomized into either ...Objective:To investigate the effectiveness and safety of manual acupuncture for memory loss and sleep quality in chronic insomniacs.Methods:A total of 60 eligible participants were enrolled and randomized into either a treatment group or a control group,with 30 cases in each group.The treatment group was intervened by manual acupuncture whereas the control group was given sham acupuncture.In the two groups,the interventions were offered once every other day and three times a week,for 8 weeks in total.Before and after the treatment,Pittsburgh sleep quality index (PSQI) and eventrelated potentials (ERPs) were used to assess the patients' sleep quality and memory,respectively.Meanwhile,adverse events were monitored and recorded.Results:After 8-week treatment,both the treatment group and the control group showed a significant decrease in the PSQI global score (P<0.001,P<0.01),and the decrease in the treatment group was more significant than that in the control group (P<0.001).The intra-group comparisons of ERPs indicated that,the latencies of N1 and P3 were shortened and the amplitudes of N1 and P3 were increased in the treatment group after the intervention,and the differences were statistically significant (P<0.05,P<0.001);in the control group,there were no significant changes in the latency and amplitude after the treatment (P>0.05).The between-group comparisons of ERPs showed that the treatment group was more effective than the control group in shortening the latency of P3 (P<0.01).Conclusion:Acupuncture can be a safe and effective treatment option for chronic insomnia coupled with memory impairment.展开更多
文摘Objective:To observe the effect of electroacupuncture on learning and memory in rats with vascular dementia.Methods:Seventy-two SD rats were randomly divided into 4 groups,a normal group,a sham operation group,a model group and an electroacupuncture (EA) pretreatment group.Modified intraluminal embolism method with nylon thread was applied to make rat model of vascular dementia,and the ability of learning and memory was observed in Morris water maze.Results:The average time of escape and latency in the rats of model group in the water maze test was prolonged,with significant difference compared with that in the sham group (P〈0.01).The average time of escape and latency and navigation test results of rats pretreated by EA had statistically significant difference compared with those of the model group (P〈0.01).Conclusion:EA pretreatment can significantly improve the ability of learning and memory of the rats with vascular dementia.
基金supported by the Project of Taishun County Science and Technology Bureau,Zhejiang Province,No.2014082~~
文摘Objective:To investigate the effects of acupoint massage on cognitive function and sleep quality in elderly patients with hypertension. Methods:A total of 68 elderly patients with hypertension were enrolled, and their ages were all over 60 years old. They were divided into a control group and a treatment group by simple random method, with 34 cases in each group. Patients in the control group were treated by routine psychological health guidance and sleep knowledge education, while patients in the treatment group were treated by acupoint massage on the base of the interventions given to the control group. Both of their treatment courses were 3 months. Pittsburgh sleep quality index (PSQI) scores and mini-mental state examination (MMSE) scores before and after treatment were recorded and compared. Results:Two groups’ PSQI scores before treatment had no significant difference (P〉0.05). After 3 months of treatment, their PSQI scores were statistically different (P〈0.05). There was also no between-group statistical difference in MMSE score before treatment (P〉0.05), but there was a significant difference after treatment (P〈0.05). Conclusion:Acupoint massage for elderly patients with primary hypertension can improve their sleep quality and enhance their cognitive function, thus it is worthy of being applied in clinical nursing work.
基金Scientific Project of National Science & Technology Pillar Program During the Eleventh Five-year Plan Period(国家“十一五”科技支撑计划项目,2007BAI10B01-027)Shanghai Municipal Commission of Health and Family Planning,Scientific and Technological Innovation Project of TCM:Mobile Internet-based Insomnia Rehabilitation Prevention (Chronic Disease Management) Guidance Platform(上海市卫生和计划生育委员会中医药科技创新项目——基于移动互联网的失眠症“治未病”康复预防(慢病管理)指导平台,ZYKC20161016).
文摘Objective:To investigate the effectiveness and safety of manual acupuncture for memory loss and sleep quality in chronic insomniacs.Methods:A total of 60 eligible participants were enrolled and randomized into either a treatment group or a control group,with 30 cases in each group.The treatment group was intervened by manual acupuncture whereas the control group was given sham acupuncture.In the two groups,the interventions were offered once every other day and three times a week,for 8 weeks in total.Before and after the treatment,Pittsburgh sleep quality index (PSQI) and eventrelated potentials (ERPs) were used to assess the patients' sleep quality and memory,respectively.Meanwhile,adverse events were monitored and recorded.Results:After 8-week treatment,both the treatment group and the control group showed a significant decrease in the PSQI global score (P<0.001,P<0.01),and the decrease in the treatment group was more significant than that in the control group (P<0.001).The intra-group comparisons of ERPs indicated that,the latencies of N1 and P3 were shortened and the amplitudes of N1 and P3 were increased in the treatment group after the intervention,and the differences were statistically significant (P<0.05,P<0.001);in the control group,there were no significant changes in the latency and amplitude after the treatment (P>0.05).The between-group comparisons of ERPs showed that the treatment group was more effective than the control group in shortening the latency of P3 (P<0.01).Conclusion:Acupuncture can be a safe and effective treatment option for chronic insomnia coupled with memory impairment.