目的探讨集体心理治疗对缓解期精神分裂症记忆功能改善的作用。方法将60例经急性期治疗后的精神分裂症患者随机分为研究组及对照组,对照组实行常规治疗,包括药物治疗及一般工娱疗;研究组在此基础上辅以集体心理治疗。治疗前后分别应用W ...目的探讨集体心理治疗对缓解期精神分裂症记忆功能改善的作用。方法将60例经急性期治疗后的精神分裂症患者随机分为研究组及对照组,对照组实行常规治疗,包括药物治疗及一般工娱疗;研究组在此基础上辅以集体心理治疗。治疗前后分别应用W A IS、W CST及临床记忆量表评分。结果治疗后两组W A IS、W CST及临床记忆量表评分较治疗前有明显改善(t=2.563～4.256,P<0.05)。其中以联合集体心理治疗的联想学习、记忆商数、W CST正确百分数和随机错误数成绩较常规治疗为好。结论集体心理治疗对精神分裂症记忆功能的改善有积极意义。展开更多
目的调查并分析宫颈癌患者患病期间的症状发生情况及严重程度,全面了解其症状群,以期提高临床护理工作的针对性和有效性。方法便利抽样法选取2012年11月至2013年8月在上海市第一妇婴保健院住院手术的92名宫颈癌患者为研究对象,采用中文...目的调查并分析宫颈癌患者患病期间的症状发生情况及严重程度,全面了解其症状群,以期提高临床护理工作的针对性和有效性。方法便利抽样法选取2012年11月至2013年8月在上海市第一妇婴保健院住院手术的92名宫颈癌患者为研究对象,采用中文版记忆症状评估量表(Chinese version memorial symptom assessment scale,MSAS-Ch)对其进行调查,并分析其调查结果。结果发生频度最高的症状是缺乏活力/乏力(占98.91%),其次是感到悲伤(占97.83%),再次为睡眠不好及没有食欲(占96.74%);症状严重程度评分依次是脱发(3.06±1.28)分、感到"看起来不像自己"(2.74±1.28)分、皮肤改变(2.48±1.29)分,其次是乏力(1.86±0.88)分、睡眠不好(1.85±0.89)分、感到悲伤(1.76±0.76)分、没有食欲(1.71±0.98)分和急躁易怒(1.71±0.98)分。因子分析得出的7个公因子的累计方差贡献率达98.354%,分别为乏力-负面心理症状群、自我形象紊乱症状群、治疗相关症状群、胃肠道症状群、体重下降-皮肤瘙痒症状群、拒性-焦虑症状群、厌食-病态行为症状群,其中因子1、2、3解释总体方差的88.953%。结论乏力-心理症状群、自我形象紊乱症状群和治疗相关症状群是宫颈癌较为常见的症状群。展开更多
Objective: To examine the neuropsychological profile of dementia patients fro m a community- based autopsy sample of dementia, comparing Alzheimer disease (A D), Lewy body pathology (LBP) alone, and LBP with coexisten...Objective: To examine the neuropsychological profile of dementia patients fro m a community- based autopsy sample of dementia, comparing Alzheimer disease (A D), Lewy body pathology (LBP) alone, and LBP with coexistent AD (AD/LBP). Methods: The authors reviewed 135 subjects from a community- based study of dementia for wh om autopsy and brain tissue was available. Diagnostic groups were determined acc ording to standard neuropathologic methods and criteria, and the presence of LBs was determined using α - synuclein immunostaining. Neuropathologically define d diagnostic groups of AD, AD/LBP, and LBP were examined for differences on neur opsychological test performance at the time of initial study enrollment. Results : There were 48 patients with AD alone, 65 with LB and AD pathology (AD/LBP), an d 22 with LBP alone (LBP alone). There were no significant differences between g roups demographically or on performance of enrollment Mini- Mental State Examin ation (MMSE) or Dementia Rating Scale (DRS). AD patients performed worse than th e LBP patients on memory measures (Fuld Object Memory Evaluation Delayed Recall, Wechsler Memory Scale Logical Memory Immediate and Delayed Recall; p < 0.05) an d a naming task (Consortium to Establish a Registry for Alzheimer’ s Disease Na ming; p < 0.05). LBP patients were more impaired than AD patients on executive f unction (Trail Making Test Part B; p < 0.05) and attention tasks (Wechsler Adult Intelligence Scale- Revised Digit Span; p < 0.05). Decline in MMSE and DRS sco res over time were greatest in the patients with AD/LBP. Conclusions: In a commu nity- based sample of older, medically complicated patients with dementia, ther e are neuropsychological differences between dementia subtypes at the time of di agnosis. In particular, patients with Alzheimer disease (AD) alone and AD/Lewy b ody pathology (LBP) had more severe memory impairment than patients with LBP. LB P alone was associated with more severe executive dysfunction. Patients with AD/ LBP had the most rapid rate of cognitive decline.展开更多
文摘目的探讨集体心理治疗对缓解期精神分裂症记忆功能改善的作用。方法将60例经急性期治疗后的精神分裂症患者随机分为研究组及对照组,对照组实行常规治疗,包括药物治疗及一般工娱疗;研究组在此基础上辅以集体心理治疗。治疗前后分别应用W A IS、W CST及临床记忆量表评分。结果治疗后两组W A IS、W CST及临床记忆量表评分较治疗前有明显改善(t=2.563～4.256,P<0.05)。其中以联合集体心理治疗的联想学习、记忆商数、W CST正确百分数和随机错误数成绩较常规治疗为好。结论集体心理治疗对精神分裂症记忆功能的改善有积极意义。
文摘目的调查并分析宫颈癌患者患病期间的症状发生情况及严重程度,全面了解其症状群,以期提高临床护理工作的针对性和有效性。方法便利抽样法选取2012年11月至2013年8月在上海市第一妇婴保健院住院手术的92名宫颈癌患者为研究对象,采用中文版记忆症状评估量表(Chinese version memorial symptom assessment scale,MSAS-Ch)对其进行调查,并分析其调查结果。结果发生频度最高的症状是缺乏活力/乏力(占98.91%),其次是感到悲伤(占97.83%),再次为睡眠不好及没有食欲(占96.74%);症状严重程度评分依次是脱发(3.06±1.28)分、感到"看起来不像自己"(2.74±1.28)分、皮肤改变(2.48±1.29)分,其次是乏力(1.86±0.88)分、睡眠不好(1.85±0.89)分、感到悲伤(1.76±0.76)分、没有食欲(1.71±0.98)分和急躁易怒(1.71±0.98)分。因子分析得出的7个公因子的累计方差贡献率达98.354%,分别为乏力-负面心理症状群、自我形象紊乱症状群、治疗相关症状群、胃肠道症状群、体重下降-皮肤瘙痒症状群、拒性-焦虑症状群、厌食-病态行为症状群,其中因子1、2、3解释总体方差的88.953%。结论乏力-心理症状群、自我形象紊乱症状群和治疗相关症状群是宫颈癌较为常见的症状群。
文摘Objective: To examine the neuropsychological profile of dementia patients fro m a community- based autopsy sample of dementia, comparing Alzheimer disease (A D), Lewy body pathology (LBP) alone, and LBP with coexistent AD (AD/LBP). Methods: The authors reviewed 135 subjects from a community- based study of dementia for wh om autopsy and brain tissue was available. Diagnostic groups were determined acc ording to standard neuropathologic methods and criteria, and the presence of LBs was determined using α - synuclein immunostaining. Neuropathologically define d diagnostic groups of AD, AD/LBP, and LBP were examined for differences on neur opsychological test performance at the time of initial study enrollment. Results : There were 48 patients with AD alone, 65 with LB and AD pathology (AD/LBP), an d 22 with LBP alone (LBP alone). There were no significant differences between g roups demographically or on performance of enrollment Mini- Mental State Examin ation (MMSE) or Dementia Rating Scale (DRS). AD patients performed worse than th e LBP patients on memory measures (Fuld Object Memory Evaluation Delayed Recall, Wechsler Memory Scale Logical Memory Immediate and Delayed Recall; p < 0.05) an d a naming task (Consortium to Establish a Registry for Alzheimer’ s Disease Na ming; p < 0.05). LBP patients were more impaired than AD patients on executive f unction (Trail Making Test Part B; p < 0.05) and attention tasks (Wechsler Adult Intelligence Scale- Revised Digit Span; p < 0.05). Decline in MMSE and DRS sco res over time were greatest in the patients with AD/LBP. Conclusions: In a commu nity- based sample of older, medically complicated patients with dementia, ther e are neuropsychological differences between dementia subtypes at the time of di agnosis. In particular, patients with Alzheimer disease (AD) alone and AD/Lewy b ody pathology (LBP) had more severe memory impairment than patients with LBP. LB P alone was associated with more severe executive dysfunction. Patients with AD/ LBP had the most rapid rate of cognitive decline.
