Froth flotation of scheelite has regained new focus since the 2010s and research regarding floatability and reagents has made great progress over the years. The main objective was and remains the selective flotation o...Froth flotation of scheelite has regained new focus since the 2010s and research regarding floatability and reagents has made great progress over the years. The main objective was and remains the selective flotation of scheelite from other calcium-bearing minerals, in particular calcite, fluorite and apatite. Due to similar properties, most attempts have limited success or only specific application(linked to a type of ore or a location). This article aims at reviewing all general physical-chemical information on froth flotation of scheelite, including electrokinetic properties, influence of p H and already existing reagents as well as ones still under examination. It appears that chelating or mixed collectors and modified versions of sodium silicate and quebracho hold great promise for scheelite flotation, while the use of said depressants and/or promoters seems inevitable.展开更多
The growth mechanism of spectinomycin dihydrochloride crystal in pure water and acetone-water mixture at different temperatures has been studied by induction period measurement. The induction period was measured visua...The growth mechanism of spectinomycin dihydrochloride crystal in pure water and acetone-water mixture at different temperatures has been studied by induction period measurement. The induction period was measured visually. The solid-liquid interfacial tension was determined on the basis of classical homogenous nucleation theory and the surface entropy factor was calculated. It was shown that the interfacial tension and surface entropy factor increased with the increase of acetone concentration and the decrease of temperature. It was demonstrated that the growth mechanism of spectinomycin dihydrochloride crystal was controlled by birth and spread growth in pure water or in acetone-water mixture at high temperatures and turned from birth and spread growth to spiral growth with the increase of acetone concentration in acetone-water mixture at low temperatures.展开更多
The similarities of the non-linear chemical （NLC） fingerprints of Radix Glycyrrhizaes from four producing areas and eight other traditional Chinese medicines （TCMs） were calculated, using a systemic similarity cal...The similarities of the non-linear chemical （NLC） fingerprints of Radix Glycyrrhizaes from four producing areas and eight other traditional Chinese medicines （TCMs） were calculated, using a systemic similarity calculation method proposed and three other main calculation ones （Euclidean distance, correlation coefficient and included angle cosine）. All of the correlation coefficient similarities of different TCMs are higher than 0.952, and the included angle cosines are all higher than 0.962. So, both the conelation coefficient and included angle cosine similarities are unable to be used as the criteria for quantitatively evaluating the similarities of NLC fingerprints of TCMs. Although all of the Euclidean distance similarities of Berry Liquorices from four producing areas are less than 73, those of the other eight TCMs are all more than 180. The Euclidean distance cannot reflect the relative magnitudes of the feature differences in the NLC fingerprints very correctly. The systemic similarity method is the best among the four ones. All of the systemic similarities of Berry Liquorices from the four producing areas are higher than 0.962, while those of the other eight TCMs are all lower than 0.805, and the systemic similarity can reflect the differences between samples most faithfully, and can be used as a quantitative one evaluating the similarities of NLC fingerprints of TCMs, by which TCM could be distinguished and evaluated quickly, simply and exactly.展开更多
Because of the influence of conventio n al ammunition working in high rotation,high overloading,high temperature,hig h pressure and other harsh environments during the launch,it is difficult to m easure the initial ve...Because of the influence of conventio n al ammunition working in high rotation,high overloading,high temperature,hig h pressure and other harsh environments during the launch,it is difficult to m easure the initial velocity of projectile muzzle.This paper analyzes and compar es each sort of characteristics of several ty pical initial velocity measurement methods of projectile muzzle both at home and abroad,and proposes the development trend based on current research and practi cal aplication.展开更多
Most commentators use the term ＂modern philosophy＂ for the post-Descartes era--an era of unprecedented growth for the modern sciences and, especially the empirical sciences. Even assuming that the feud between the r...Most commentators use the term ＂modern philosophy＂ for the post-Descartes era--an era of unprecedented growth for the modern sciences and, especially the empirical sciences. Even assuming that the feud between the rationalists and the empiricists during this period yielded no other benefits, it was beneficial enough to turn ＂experience＂ into an important pillar of the acquisition of knowledge in the subsequent philosophy. It was this ＂experience-mindedness＂ that drove away the Aristotelian ＂essentialist＂ perspective and replaced it with ＂nominalism.＂ By describing the genesis and emergence of the ＂nominalist-empirical＂ perspective in analytic philosophy as one of the branches of the human sciences, this article strives to advance the claim that philosophical thinking continues to flourish in the absence of ＂realist thinking about universals＂ and that philosophizing does not fundamentally rest on universals.展开更多
The research concerns Roman medical galactology, galaktologia iatrike （γαλακτσλσγια ιατρικη）, i.e. the ancient knowledge of milk and its by-products in medical procedures as described by Celsus in...The research concerns Roman medical galactology, galaktologia iatrike （γαλακτσλσγια ιατρικη）, i.e. the ancient knowledge of milk and its by-products in medical procedures as described by Celsus in his treatise entitled De medicina. The authors elaborate on the sources of Celsus＇ medical theory of milk, comment on the place of the Roman author＇s theory against the doctrinal background of other medical writers of the period, demonstrate pharmacological characteristics attributed to milk and milk-obtained products by Celsus, specify main cures in which milk and its by-products were made use of as either simple or compound medicines, give examples of the latter, delineate the progress of the theory on milk＇s medicinal use, and finally comment on the role of milk and milk-obtained products in the diet of the Mediterranean.展开更多
Traditional Chinese medicines(TCMs)have been used to prevent and treat various diseases for thousands of years.Promoting efficacy and reducing toxicity by the compatibility theory of TCMs has attracted increasing atte...Traditional Chinese medicines(TCMs)have been used to prevent and treat various diseases for thousands of years.Promoting efficacy and reducing toxicity by the compatibility theory of TCMs has attracted increasing attention,especially for the toxicity of herbs.Studies have pointed out the interactions between the active compounds of herbs and transporters in the detoxification process of toxic compounds.Here,we summarize data on five toxic herbs commonly used in TCMs and their related efflux transporters to reduce toxicity to offer a scientific rationale for the compatibility principle of TCMs and provide guidance for the rational clinical use of TCMs.展开更多
It is discovered by the authors of this article thatchronic hepatitis and hepatocirrhosis (hereinafterchronic hepatopathy for short) are often accompaniedby some diseases of endocrine and mammary glands.The authors ha...It is discovered by the authors of this article thatchronic hepatitis and hepatocirrhosis (hereinafterchronic hepatopathy for short) are often accompaniedby some diseases of endocrine and mammary glands.The authors have studied the pathogenesis andtreatment of the complications as presented in thefollowing.展开更多
OBJECTIVE:The theory of lung being connected with large intestine,which is a major topic in Traditional Chinese Medicine(TCM),has guided clinical practice for thousands of years in China.METHODS:In this study,we analy...OBJECTIVE:The theory of lung being connected with large intestine,which is a major topic in Traditional Chinese Medicine(TCM),has guided clinical practice for thousands of years in China.METHODS:In this study,we analyzed the history,main contents,clinical application,and material basis of the theory,to attempt to improve the potential clinical significance of "lung being connected with large intestine" in China.RESULTS:The lung being connected with large intestine was first described in "Huang Di Nei Jing",and formed one of the basic theories of TCM.For thousands of years,the majority of TCM practitioners explored this theory continuously,leading to its development and use as an important theory in the guidance of TCM clinics In the last decade,researchers in the field of integrated TCM and Western medicine have studied clinical applications and biomedical mechanisms with experimental methods to explore the implications of the theory.CONCLUSION:With the further development of science and technology,research concerning the theory of lung being connected with large intestine will be greatly stimulated and contribute to the modernization of TCM.展开更多
In this paper,we analyze the four distinct characteristics of information on Traditional Chinese Medicine(TCM), namely epistemological information,phenomenon information, overall information, and time information. The...In this paper,we analyze the four distinct characteristics of information on Traditional Chinese Medicine(TCM), namely epistemological information,phenomenon information, overall information, and time information. These characteristics bear to some extent strong similarity to the three characteristics of "Big Data", namely integrity data, fuzzy data and correlation data, so the advent of the age of "Big Data" is bound to create good opportunities for the development of TCM informatics and is also be expected to provide methods and techniques for processing and analysis of TCM "comprehensive data".展开更多
Most current commercially important hydrocolloids could be considered as dietary fibers.A great deal of research has focused on the bio-function of hydrocolloid materials resulting from their chemical structure,includ...Most current commercially important hydrocolloids could be considered as dietary fibers.A great deal of research has focused on the bio-function of hydrocolloid materials resulting from their chemical structure,including antioxidant properties,bacteriostatic capacity and cancer prevention.However,the colloidal properties of hydrocolloids in water-holding,high viscosity,gelling and indigestion,which are characterized by macromolecules,also contribute to the human health.Therefore,the nutritional value of hydrocolloids deriving from their colloid properties is defined as colloid nutriology.More specifically,hydrocolloids in this study refer to dietary fibers which are metabolically inert or fermented in the colon or large intestine.Based on this conception,this mini-review attempts to elaborate the nutritional value of hydrocolloids resulting from its colloidal properties.展开更多
Objective To explore the best clinical treatment for infantile malnutrition. Methods Three hundred and forty-three patients were randomly divided into a pricking at Sìfèng （四缝 EX-UE 10） group （priking g...Objective To explore the best clinical treatment for infantile malnutrition. Methods Three hundred and forty-three patients were randomly divided into a pricking at Sìfèng （四缝 EX-UE 10） group （priking group, n=105）, a Chinese herbs group （n=85） and a pricking and Chinese herbs group （n=153）. The improvements of the clinical symptoms of all three groups were evaluated after the treatment. Results The results of these treatments for all the patients were satisfying. The effective rate of the pricking and Chinese herbs group, which was 98.7 % （151/153）, was superior to that of 94.3 % （99/105） （P0.05） in the pricking group and 91.8% （78/85） in the Chinese herbs group （P0.01）, while no differences in effective rate were found between the pricking group and the Chinese herbs group （P0.05）. Conclusion The pricking at Sìfèng （四缝 EX-UE 10） combined with Chinese herbs is the best treatment for infantile malnutrition.展开更多
Dry eye syndrome （DES） is a commonly encountered ophthalmological disease, with a relatively high incidence, and expects an effective treatment method. Acupunctureoxibustion therapy promotes tear production of lacri...Dry eye syndrome （DES） is a commonly encountered ophthalmological disease, with a relatively high incidence, and expects an effective treatment method. Acupunctureoxibustion therapy promotes tear production of lacrimal gland without causing a trauma, and thus has a great advantage in treating DES. Through literature analysis, this article summarized the research progress in both clinical practice and mechanism of acupuncture- moxibustion in treating DES during the recent 10 years, for providing valuable references for the application of acupuncture-moxibustion for DES.展开更多
Objective： To observe the effect of combined acupuncture and Chinese herbal formula on the motor function and activities of daily living （ADL） of post-stroke patients and further evaluate the resultant clinical eff...Objective： To observe the effect of combined acupuncture and Chinese herbal formula on the motor function and activities of daily living （ADL） of post-stroke patients and further evaluate the resultant clinical efficacy. Methods： A total of 80 acute stroke patients were randomly divided into a control group （40 cases） and an observation group （40 cases）. Conventional Western medicine management was employed in the control group, while additional acupuncture and Chinese herbal formula were employed in the observation group. After completing the sessions of treatment, changes of the motor function （using the US National Institutes of Health Stroke Scale, NIHSS） and activities of daily living （using Barthel Index） were measured. Results： The total effective rate in the observation group was 87.5%, versus 62.5% in the control group, showing a statistical difference （P〈0.05）. After the treatment, the motor function and activities of daily living of patients in both groups were markedly improved （P〈0.05）, and those in the observation group presented with a better result （P〈0.05）. Conclusion： Conventional Western medicine management coupled with acupuncture and Chinese herbal formula are beneficial to the treatment and rehabilitation of patients with cerebral infarction.展开更多
Owing to the importance of drug delivery in cancer or other diseases' therapy, the targeted drug delivery (TDD) system has been attracting enormous interest. Herein, we model the TDD system and design a novel rod-...Owing to the importance of drug delivery in cancer or other diseases' therapy, the targeted drug delivery (TDD) system has been attracting enormous interest. Herein, we model the TDD system and design a novel rod-like nanocarrier by using the coarse grained model-based density functional theory, which combines a modified fundamental measure theory for the excluded-volume effects, Wertheim's first-order thermodynamics perturbation theory for the chain connectivity and the mean field approximation for van der Waals attraction. For comparison, the monomer nanocarrier TDD system and the no nanocarrier one are also investigated. The results indicate that the drug delivery capacity of rod-like nanocarriers is about 62 times that of the no nanocarrier one, and about 6 times that of the monomer nanocarriers. The reason is that the rod-like nanocarriers would self-assemble into the smectic phase perpendicular to the membrane surface. It is the self-assembly of the rod-like nanocarriers that yields the driving force for the targeted delivery of drugs inside the cell membrane. By contrast, the conventional monomer nanocarrier drug delivery system lacks the driving force to deliver the drugs into the cell membrane. In short, the novel rod-like nanocarrier TDD system may improve the drug delivery efficiency. Although the model in this work is simple, it is expected that the system may provide a new perspective for cancer targeted therapy.展开更多
基金the financial support of the Optim Ore projectthe European Union’s Horizon 2020 research and innovation programme under grant agreement No. 642201
文摘Froth flotation of scheelite has regained new focus since the 2010s and research regarding floatability and reagents has made great progress over the years. The main objective was and remains the selective flotation of scheelite from other calcium-bearing minerals, in particular calcite, fluorite and apatite. Due to similar properties, most attempts have limited success or only specific application(linked to a type of ore or a location). This article aims at reviewing all general physical-chemical information on froth flotation of scheelite, including electrokinetic properties, influence of p H and already existing reagents as well as ones still under examination. It appears that chelating or mixed collectors and modified versions of sodium silicate and quebracho hold great promise for scheelite flotation, while the use of said depressants and/or promoters seems inevitable.
文摘The growth mechanism of spectinomycin dihydrochloride crystal in pure water and acetone-water mixture at different temperatures has been studied by induction period measurement. The induction period was measured visually. The solid-liquid interfacial tension was determined on the basis of classical homogenous nucleation theory and the surface entropy factor was calculated. It was shown that the interfacial tension and surface entropy factor increased with the increase of acetone concentration and the decrease of temperature. It was demonstrated that the growth mechanism of spectinomycin dihydrochloride crystal was controlled by birth and spread growth in pure water or in acetone-water mixture at high temperatures and turned from birth and spread growth to spiral growth with the increase of acetone concentration in acetone-water mixture at low temperatures.
基金Project(2009GJD20033) supported by the National Science and Technology Ministry of China
文摘The similarities of the non-linear chemical （NLC） fingerprints of Radix Glycyrrhizaes from four producing areas and eight other traditional Chinese medicines （TCMs） were calculated, using a systemic similarity calculation method proposed and three other main calculation ones （Euclidean distance, correlation coefficient and included angle cosine）. All of the correlation coefficient similarities of different TCMs are higher than 0.952, and the included angle cosines are all higher than 0.962. So, both the conelation coefficient and included angle cosine similarities are unable to be used as the criteria for quantitatively evaluating the similarities of NLC fingerprints of TCMs. Although all of the Euclidean distance similarities of Berry Liquorices from four producing areas are less than 73, those of the other eight TCMs are all more than 180. The Euclidean distance cannot reflect the relative magnitudes of the feature differences in the NLC fingerprints very correctly. The systemic similarity method is the best among the four ones. All of the systemic similarities of Berry Liquorices from the four producing areas are higher than 0.962, while those of the other eight TCMs are all lower than 0.805, and the systemic similarity can reflect the differences between samples most faithfully, and can be used as a quantitative one evaluating the similarities of NLC fingerprints of TCMs, by which TCM could be distinguished and evaluated quickly, simply and exactly.
基金Natural Science Foundation of Shanxi Province (No.2010011022-4)
文摘Because of the influence of conventio n al ammunition working in high rotation,high overloading,high temperature,hig h pressure and other harsh environments during the launch,it is difficult to m easure the initial velocity of projectile muzzle.This paper analyzes and compar es each sort of characteristics of several ty pical initial velocity measurement methods of projectile muzzle both at home and abroad,and proposes the development trend based on current research and practi cal aplication.
文摘Most commentators use the term ＂modern philosophy＂ for the post-Descartes era--an era of unprecedented growth for the modern sciences and, especially the empirical sciences. Even assuming that the feud between the rationalists and the empiricists during this period yielded no other benefits, it was beneficial enough to turn ＂experience＂ into an important pillar of the acquisition of knowledge in the subsequent philosophy. It was this ＂experience-mindedness＂ that drove away the Aristotelian ＂essentialist＂ perspective and replaced it with ＂nominalism.＂ By describing the genesis and emergence of the ＂nominalist-empirical＂ perspective in analytic philosophy as one of the branches of the human sciences, this article strives to advance the claim that philosophical thinking continues to flourish in the absence of ＂realist thinking about universals＂ and that philosophizing does not fundamentally rest on universals.
文摘The research concerns Roman medical galactology, galaktologia iatrike （γαλακτσλσγια ιατρικη）, i.e. the ancient knowledge of milk and its by-products in medical procedures as described by Celsus in his treatise entitled De medicina. The authors elaborate on the sources of Celsus＇ medical theory of milk, comment on the place of the Roman author＇s theory against the doctrinal background of other medical writers of the period, demonstrate pharmacological characteristics attributed to milk and milk-obtained products by Celsus, specify main cures in which milk and its by-products were made use of as either simple or compound medicines, give examples of the latter, delineate the progress of the theory on milk＇s medicinal use, and finally comment on the role of milk and milk-obtained products in the diet of the Mediterranean.
基金We thank for the funding support from the Science and Technology Development Fund,Macao SAR(No.0040/2020/A and No.0075/2019/AMJ).
文摘Traditional Chinese medicines(TCMs)have been used to prevent and treat various diseases for thousands of years.Promoting efficacy and reducing toxicity by the compatibility theory of TCMs has attracted increasing attention,especially for the toxicity of herbs.Studies have pointed out the interactions between the active compounds of herbs and transporters in the detoxification process of toxic compounds.Here,we summarize data on five toxic herbs commonly used in TCMs and their related efflux transporters to reduce toxicity to offer a scientific rationale for the compatibility principle of TCMs and provide guidance for the rational clinical use of TCMs.
文摘It is discovered by the authors of this article thatchronic hepatitis and hepatocirrhosis (hereinafterchronic hepatopathy for short) are often accompaniedby some diseases of endocrine and mammary glands.The authors have studied the pathogenesis andtreatment of the complications as presented in thefollowing.
基金Supported by The National Basic Research Program of China(973 Program)(2009CB522707)the Distinguished Young Scholars Project from the Education Department of Hubei Province(Q20101081)the Science Fund for Distinguished Young Scholars of Wuhan City(D201050231081)
文摘OBJECTIVE:The theory of lung being connected with large intestine,which is a major topic in Traditional Chinese Medicine(TCM),has guided clinical practice for thousands of years in China.METHODS:In this study,we analyzed the history,main contents,clinical application,and material basis of the theory,to attempt to improve the potential clinical significance of "lung being connected with large intestine" in China.RESULTS:The lung being connected with large intestine was first described in "Huang Di Nei Jing",and formed one of the basic theories of TCM.For thousands of years,the majority of TCM practitioners explored this theory continuously,leading to its development and use as an important theory in the guidance of TCM clinics In the last decade,researchers in the field of integrated TCM and Western medicine have studied clinical applications and biomedical mechanisms with experimental methods to explore the implications of the theory.CONCLUSION:With the further development of science and technology,research concerning the theory of lung being connected with large intestine will be greatly stimulated and contribute to the modernization of TCM.
基金Supported by the Fundamental Research Funds for the Central public welfare research institutes(No.ZZ070822)Innovative Research Team in CACMS(No.PY1306)
文摘In this paper,we analyze the four distinct characteristics of information on Traditional Chinese Medicine(TCM), namely epistemological information,phenomenon information, overall information, and time information. These characteristics bear to some extent strong similarity to the three characteristics of "Big Data", namely integrity data, fuzzy data and correlation data, so the advent of the age of "Big Data" is bound to create good opportunities for the development of TCM informatics and is also be expected to provide methods and techniques for processing and analysis of TCM "comprehensive data".
基金supported by the National Natural Science Foundation of China(Grant No.31772015)
文摘Most current commercially important hydrocolloids could be considered as dietary fibers.A great deal of research has focused on the bio-function of hydrocolloid materials resulting from their chemical structure,including antioxidant properties,bacteriostatic capacity and cancer prevention.However,the colloidal properties of hydrocolloids in water-holding,high viscosity,gelling and indigestion,which are characterized by macromolecules,also contribute to the human health.Therefore,the nutritional value of hydrocolloids deriving from their colloid properties is defined as colloid nutriology.More specifically,hydrocolloids in this study refer to dietary fibers which are metabolically inert or fermented in the colon or large intestine.Based on this conception,this mini-review attempts to elaborate the nutritional value of hydrocolloids resulting from its colloidal properties.
文摘Objective To explore the best clinical treatment for infantile malnutrition. Methods Three hundred and forty-three patients were randomly divided into a pricking at Sìfèng （四缝 EX-UE 10） group （priking group, n=105）, a Chinese herbs group （n=85） and a pricking and Chinese herbs group （n=153）. The improvements of the clinical symptoms of all three groups were evaluated after the treatment. Results The results of these treatments for all the patients were satisfying. The effective rate of the pricking and Chinese herbs group, which was 98.7 % （151/153）, was superior to that of 94.3 % （99/105） （P0.05） in the pricking group and 91.8% （78/85） in the Chinese herbs group （P0.01）, while no differences in effective rate were found between the pricking group and the Chinese herbs group （P0.05）. Conclusion The pricking at Sìfèng （四缝 EX-UE 10） combined with Chinese herbs is the best treatment for infantile malnutrition.
文摘Dry eye syndrome （DES） is a commonly encountered ophthalmological disease, with a relatively high incidence, and expects an effective treatment method. Acupunctureoxibustion therapy promotes tear production of lacrimal gland without causing a trauma, and thus has a great advantage in treating DES. Through literature analysis, this article summarized the research progress in both clinical practice and mechanism of acupuncture- moxibustion in treating DES during the recent 10 years, for providing valuable references for the application of acupuncture-moxibustion for DES.
文摘Objective： To observe the effect of combined acupuncture and Chinese herbal formula on the motor function and activities of daily living （ADL） of post-stroke patients and further evaluate the resultant clinical efficacy. Methods： A total of 80 acute stroke patients were randomly divided into a control group （40 cases） and an observation group （40 cases）. Conventional Western medicine management was employed in the control group, while additional acupuncture and Chinese herbal formula were employed in the observation group. After completing the sessions of treatment, changes of the motor function （using the US National Institutes of Health Stroke Scale, NIHSS） and activities of daily living （using Barthel Index） were measured. Results： The total effective rate in the observation group was 87.5%, versus 62.5% in the control group, showing a statistical difference （P〈0.05）. After the treatment, the motor function and activities of daily living of patients in both groups were markedly improved （P〈0.05）, and those in the observation group presented with a better result （P〈0.05）. Conclusion： Conventional Western medicine management coupled with acupuncture and Chinese herbal formula are beneficial to the treatment and rehabilitation of patients with cerebral infarction.
基金supported by the National Natural Science Foundation of China (20874005, 20736002, 20821004)the National Basic Research Program of China (2011CB706900)+1 种基金Huo Yingdong Fundamental Research Foundation (121070)Novel Team (IRT0807) from Ministry of Education and the Chemical Grid Project of BUCT
文摘Owing to the importance of drug delivery in cancer or other diseases' therapy, the targeted drug delivery (TDD) system has been attracting enormous interest. Herein, we model the TDD system and design a novel rod-like nanocarrier by using the coarse grained model-based density functional theory, which combines a modified fundamental measure theory for the excluded-volume effects, Wertheim's first-order thermodynamics perturbation theory for the chain connectivity and the mean field approximation for van der Waals attraction. For comparison, the monomer nanocarrier TDD system and the no nanocarrier one are also investigated. The results indicate that the drug delivery capacity of rod-like nanocarriers is about 62 times that of the no nanocarrier one, and about 6 times that of the monomer nanocarriers. The reason is that the rod-like nanocarriers would self-assemble into the smectic phase perpendicular to the membrane surface. It is the self-assembly of the rod-like nanocarriers that yields the driving force for the targeted delivery of drugs inside the cell membrane. By contrast, the conventional monomer nanocarrier drug delivery system lacks the driving force to deliver the drugs into the cell membrane. In short, the novel rod-like nanocarrier TDD system may improve the drug delivery efficiency. Although the model in this work is simple, it is expected that the system may provide a new perspective for cancer targeted therapy.
