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我国家具产业的设计创意与创新研究 被引量:2
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作者 凌继尧 张晓刚 《创意与设计》 2014年第4期11-18,共8页
家具是人们的必需消费品,这个前提条件为行业定义了一个很大的市场。家具行业也是历史非常悠久的行业,它伴随着人们的衣食住行基本需要,并随着人们生活水平的提高而不断发展。尤其是新世纪以来,我国的城市化和小城镇化建设步伐不断加快... 家具是人们的必需消费品,这个前提条件为行业定义了一个很大的市场。家具行业也是历史非常悠久的行业,它伴随着人们的衣食住行基本需要,并随着人们生活水平的提高而不断发展。尤其是新世纪以来,我国的城市化和小城镇化建设步伐不断加快,房地产市场高度繁荣,为各类家具和配套产品提供了广阔的发展空间。同时,随着工业的进步,在传统手工作业基础上,各种新工艺、新材料不断应用于家具生产中,我国的家具行业呈现出崭新的活力和面貌,整个行业水平不断提升,从以往的注重成本与价格到现在更注重设计理念、营销理念的建立,以及引进优秀国外人才,建设企业文化等,都体现了我国家具行业的进步。 展开更多
关键词 体验创造价值 差异化经营 区域特色品牌 设计细分化
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NEW DESIGNED HMBA AGENTS AS INDUCERS OFERYTHROLEUKEMIA CELL DIFFERENTIATION 被引量:1
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作者 王华力 张世馥 +1 位作者 周建平 章静波 《Chinese Medical Sciences Journal》 CAS CSCD 2002年第1期27-31,共5页
Searching for more potent and less toxic HMBA related agents. Methods. Human erythroleukemia cell K562, murine erythroleukemia cell (MEL) and its sub line MEL DS19 were used as target cells to select a cell line which... Searching for more potent and less toxic HMBA related agents. Methods. Human erythroleukemia cell K562, murine erythroleukemia cell (MEL) and its sub line MEL DS19 were used as target cells to select a cell line which is the most sensitive to HMBA, then analyzed the activity of inducing differentiati on of two new designed HMBA derivatives: HMBPA [hexamethylenebi (3 pyridin) ami de] and Co HDTA (ethylenediaminetetra acetic acid cobalt) using cell biology, c ytochemical and molecular biology techniques. Results. We found that the MEL DS19 cells were most sensitive to HMBA (benzidine positive, B+~76%). Co HDTA can inhibit the growth of MEL DS19, but induces differentiation just in a small population (B+ 2%~4.5%). Between 0.02~5μmo l/L, HMBPA induces 3%~8% cells committed to differentiation with little inhib ition of cell proliferation. 1μmol/L HMBPA and 2mmol/L HMBA together, can obvio usly increase the percentage of differentiated cell (B+~ 72%), inhibit DNA sy nthesis and accelerate β globin transcription. Conclusion. The new HMBA derivatives may provide potential cancer differentiatio n inducers. 展开更多
关键词 cell differentiation HMBA MEL cell cell cycle
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