探究益气补血化瘀汤治疗冠状动脉粥样硬化性心脏病心绞痛患者的效果。方法 选择2020年1月至2022年12月在我院治疗的冠心病心绞痛住院患者500例,随机分为中医组和参照组,各250例。参照组给予常规西医治疗,中医组在常规治疗基础上给予益...探究益气补血化瘀汤治疗冠状动脉粥样硬化性心脏病心绞痛患者的效果。方法 选择2020年1月至2022年12月在我院治疗的冠心病心绞痛住院患者500例,随机分为中医组和参照组,各250例。参照组给予常规西医治疗,中医组在常规治疗基础上给予益气补血化瘀汤治疗。比较两组中医辨证分型、心绞痛发作频率、持续时间、疼痛程度、硝酸异山梨酯用量及生活质量评分。结果 中医组治疗效果高于(92.40 vs 86.00)%参照组,组间对比差异成立(P<0.05);中医组心绞痛临床疗效中发作次数(1.57±0.48 vs 2.51±0.64)次、持续时间(1.49±0.36 vs 2.28±0.52)min、疼痛程度(1.70±0.42 vs 2.68±0.89)分及硝酸异山梨酯用量(1.03±0.35 vs 1.97±0.40)次均低于参照组,组间对比差异成立(P<0.05);中医组各项SAQ评分中躯体受限(91.35±3.44 vs 87.26±3.91)分、心绞痛稳定(91.70±3.59 vs 86.98±3.62)分、心绞痛发作(92.06±4.38 vs 87.22±4.97)分、满意程度(95.32±2.48 vs 90.07±3.11)分、疾病认知(93.05±3.68 vs 87.23±4.31)分均高于参照组,组间对比差异成立(P<0.05)。结论 益气补血化瘀汤能有效改善冠心病心绞痛患者中医证候,减轻心绞痛症状,提高生存质量,值得临床推广使用。展开更多
OBJECTIVE:To systematically review treatments of exfoliative cheilitis based on symptom patterns in terms of Traditional Chinese Medicine.METHODS:Pub Med, Cochrane Central Register of Controlled Trials and Wanfang dat...OBJECTIVE:To systematically review treatments of exfoliative cheilitis based on symptom patterns in terms of Traditional Chinese Medicine.METHODS:Pub Med, Cochrane Central Register of Controlled Trials and Wanfang data were screened for case reports, case series or clinical trials that were published in English or Chinese from January,1973 to September, 2015.The keyword of "exfoliative cheilitis or scaling cheilitis or factitious cheilitis" was used.Effectiveness or ineffectiveness was investigated as outcome for Meta analysis, which is based on effective index in each study.Response to treatment was described for case reports or case series.RESULTS:From 38 screened studies, 17 were randomized controlled trials(RCTs), 5 were single-arm trials, and 16 were case reports or case series.Three RCTs were eligible for Meta analysis and all of them compared managements between Traditional Chinese Medicine and corticosteroids for exfoliative cheilitis, which involved 223 participants.Interestingly, data of Meta analysis showed similar effect of Traditional Chinese Medicine and corticosteroids for patients with exfoliative cheilitis [relative risk ratio:1.10; 95% CI(1.00-1.21), P = 0.06].CONCLUSION:Traditional Chinese Medicine might be a substitute for corticosteroids on exfoliative cheilitis.However, the evidence and recommendation of exfoliative cheilitis managements need to be taken with caution because of the low quality of evidence in the studies obtained.展开更多
文摘探究益气补血化瘀汤治疗冠状动脉粥样硬化性心脏病心绞痛患者的效果。方法 选择2020年1月至2022年12月在我院治疗的冠心病心绞痛住院患者500例,随机分为中医组和参照组,各250例。参照组给予常规西医治疗,中医组在常规治疗基础上给予益气补血化瘀汤治疗。比较两组中医辨证分型、心绞痛发作频率、持续时间、疼痛程度、硝酸异山梨酯用量及生活质量评分。结果 中医组治疗效果高于(92.40 vs 86.00)%参照组,组间对比差异成立(P<0.05);中医组心绞痛临床疗效中发作次数(1.57±0.48 vs 2.51±0.64)次、持续时间(1.49±0.36 vs 2.28±0.52)min、疼痛程度(1.70±0.42 vs 2.68±0.89)分及硝酸异山梨酯用量(1.03±0.35 vs 1.97±0.40)次均低于参照组,组间对比差异成立(P<0.05);中医组各项SAQ评分中躯体受限(91.35±3.44 vs 87.26±3.91)分、心绞痛稳定(91.70±3.59 vs 86.98±3.62)分、心绞痛发作(92.06±4.38 vs 87.22±4.97)分、满意程度(95.32±2.48 vs 90.07±3.11)分、疾病认知(93.05±3.68 vs 87.23±4.31)分均高于参照组,组间对比差异成立(P<0.05)。结论 益气补血化瘀汤能有效改善冠心病心绞痛患者中医证候,减轻心绞痛症状,提高生存质量,值得临床推广使用。
基金Supported by National Natural Science Foundation of China(miRNA Expression Model During Oral Leukoplakia Cancerization,No.30872887)National Construction Project of Clinical Key Specialized Department[2013]544-03Shanghai Natural Science Foundation(Epigenetic Regulation through GRIM19 Mediated Abnormal Metabolism in Head and Neck Carcinogenesis,No.15ZR1424700)
文摘OBJECTIVE:To systematically review treatments of exfoliative cheilitis based on symptom patterns in terms of Traditional Chinese Medicine.METHODS:Pub Med, Cochrane Central Register of Controlled Trials and Wanfang data were screened for case reports, case series or clinical trials that were published in English or Chinese from January,1973 to September, 2015.The keyword of "exfoliative cheilitis or scaling cheilitis or factitious cheilitis" was used.Effectiveness or ineffectiveness was investigated as outcome for Meta analysis, which is based on effective index in each study.Response to treatment was described for case reports or case series.RESULTS:From 38 screened studies, 17 were randomized controlled trials(RCTs), 5 were single-arm trials, and 16 were case reports or case series.Three RCTs were eligible for Meta analysis and all of them compared managements between Traditional Chinese Medicine and corticosteroids for exfoliative cheilitis, which involved 223 participants.Interestingly, data of Meta analysis showed similar effect of Traditional Chinese Medicine and corticosteroids for patients with exfoliative cheilitis [relative risk ratio:1.10; 95% CI(1.00-1.21), P = 0.06].CONCLUSION:Traditional Chinese Medicine might be a substitute for corticosteroids on exfoliative cheilitis.However, the evidence and recommendation of exfoliative cheilitis managements need to be taken with caution because of the low quality of evidence in the studies obtained.
