OBJECTIVE The current retrospective study aims to evaluate the management of non-functioning the assessment of experience on pituitary macroadenoma through clinical, biochemical, radiological features, and treatment o...OBJECTIVE The current retrospective study aims to evaluate the management of non-functioning the assessment of experience on pituitary macroadenoma through clinical, biochemical, radiological features, and treatment outcome of patients, and to identify prognostic factors affecting progression-free survival （PFS）. METHODS Data of 55 patients macroadenoma presented to the with non-functioning pituitary Clinical Oncology and Nuclear Medicine department between 1998 and 2009 were investigated. RESULTS The most common symptom was visual disturbance （38.2%） followed by headache （27.3%）. The presence of male predominance was observed （1.4：1）. Ten patients received radio-therapy （RT） only. Extrasellar extension was the more common treatment. The overall response rate was 72.8% with completed response at 16.4%. Memory and intellectual sequelae were the most common late complications of treatment （14%）. The ten-year PFS was at 84.6%. PFS was found to be significantly better with higher dose of RT （up to 54 Gy）, treatment by both surgery and RT, absence of visual field defect, and tumor localized to sella, whereas it was not significantly affected by age and sex. CONCLUSION The data confirmed that the prevalence of mass effect and hypopituitarism in patients with non-functioning pituitary macroadenoma is elevated. Conventional external RT up to 54 Gy is safe and effective in controlling non-functioning pituitary macro- adenoma with tolerable and acceptable morbidity.展开更多
In order to overcome the limitation that rock mass instability warnings are caused by a lack of deep consideration of the inherent mechanism of disaster formation, early warning signs of rock mass instability were det...In order to overcome the limitation that rock mass instability warnings are caused by a lack of deep consideration of the inherent mechanism of disaster formation, early warning signs of rock mass instability were detected and multi-field coupling was analyzed. A multi-field coupling model of a damaged rock mass was established. The relationship between microseismic activity parameters and rock mass stability was analyzed, and a multi-parameter early warning index system was established and its solution program was compiled. Based on the D-S data fusion theory,an early warning model of rock mass instability combining multi-field coupling analysis and microseismic monitoring was constructed. Taking an underground mine stope as an object, the multi-field coupling model and its solution program were used to analyze mining response characteristics. The seismic field data were used to verify the accuracy of the multi-field coupling analysis. The early warning model was used to predict the instability of stope rock mass,and the early warning result is consistent with a real-world scenario.展开更多
Modeling and validation of full power converter wind turbine models with field measurement data are rarely reported in papers. In this paper an aggregated generic dynamic model of the wind farm consisting of full powe...Modeling and validation of full power converter wind turbine models with field measurement data are rarely reported in papers. In this paper an aggregated generic dynamic model of the wind farm consisting of full power converter wind turbines is composed and the model validation based on actual field measurements is performed. The paper is based on the measurements obtained from the real short circuit test applied to connection point of observed wind farm. The presented approach for validating the composed model and fault ride-through （FRT） capability for the whole wind park is unique in overall practice and its significance and importance is described and analyzed.展开更多
This study examines the effect of audit quality （AQ） on the earnings response coefficient （ERC） based on a sample of 1,884 firm-year observations comprising 471 firms listed on the Bursa Malaysia from 2007 to 2010...This study examines the effect of audit quality （AQ） on the earnings response coefficient （ERC） based on a sample of 1,884 firm-year observations comprising 471 firms listed on the Bursa Malaysia from 2007 to 2010. This study tests whether AQ affects ERC after controlling the established determinants of ERC： beta, growth, earnings persistence, and size. Using reverse regression, the study confirms that Big 4 is significant and positive to ERC. Auditor switching from non-Big 4 to Big 4 indicates the same results; however, the switching of auditors among Big 4 is not significant. The study thus provides systematic and comprehensive additional evidence on the effect of AQ via the measurement of Big 4; and auditor switching from non-Big 4 to Big 4 and switching among Big 4 on ERC. This is an important contribution to the literature but especially so given that the evidence comes from Malaysia, an emerging economy, whereas the existing empirical literature relates mainly to the developed countries.展开更多
In order to provide power quality monitoring activities with metrological certification, a DAS （data acquisition system） has been designed, realized and characterized. The system allows acquisition on tri-phases plu...In order to provide power quality monitoring activities with metrological certification, a DAS （data acquisition system） has been designed, realized and characterized. The system allows acquisition on tri-phases plus neutral lines picking up 499 samples per period of the fundamental at 50 Hz. To ensure certified measurements, the system gets external certified time and voltage references. The system uses a FTDI Virtual Com Port Driver to communicate data over High Speed RS232 virtual interface and it does not need any advanced programming skill. The choice to use a virtual serial communication makes the data acquisition software portable over many platforms, regardless by the development environment and by the programming language. To test the proposed device some custom software have been written in many programming language （C^#, VB6, LabView, MatLab）, moreover in order to characterize the device the most common ADC （analog to digital converter） performing test have been applied.展开更多
The large eddy simulation (LES) using the steady laminar flamelet model is applied to a simple turbulent jet flame with 33.2% H2,22.1% CH4 and 44.7% N2 at the Reynolds number of 15,200 in order to validate the numeric...The large eddy simulation (LES) using the steady laminar flamelet model is applied to a simple turbulent jet flame with 33.2% H2,22.1% CH4 and 44.7% N2 at the Reynolds number of 15,200 in order to validate the numerical methods and to investigate the flame structure.For the validation,the detailed experimental data of DLR-A flame is used.The numerical results are in reasonable agreement with experimental results except mass fractions of minor species.In the flow field,the break-down of the potential core,the vortex structure and the mixing intensity are well captured.In the combustion field,mass fractions of major species (H2O,CO2,CO) are well predicted quantitatively.Minor species are well predicted qualitatively.In the present study,the simulations conducted on the Cartesian and cylindrical grids with approximately 6.6× 10 5 nodes are compared.展开更多
In this paper, we consider the singular isothermal sphere lensing model that has a spherically symmetric power-law mass dis- tribution ρtot（r） - r-γ. We investigate whether the mass density power-law index y is co...In this paper, we consider the singular isothermal sphere lensing model that has a spherically symmetric power-law mass dis- tribution ρtot（r） - r-γ. We investigate whether the mass density power-law index y is cosmologically evolutionary by using the strong gravitational lensing （SGL） observation, in combination with other cosmological observations. We also check whether the constraint result of y is affected by the cosmological model, by considering several simple dynamical dark energy models. We find that the constraint on y is mainly decided by the SGL observation and independent of the cosmological model, and we find no evidence for the evolution of y from the SGL observation.展开更多
文摘OBJECTIVE The current retrospective study aims to evaluate the management of non-functioning the assessment of experience on pituitary macroadenoma through clinical, biochemical, radiological features, and treatment outcome of patients, and to identify prognostic factors affecting progression-free survival （PFS）. METHODS Data of 55 patients macroadenoma presented to the with non-functioning pituitary Clinical Oncology and Nuclear Medicine department between 1998 and 2009 were investigated. RESULTS The most common symptom was visual disturbance （38.2%） followed by headache （27.3%）. The presence of male predominance was observed （1.4：1）. Ten patients received radio-therapy （RT） only. Extrasellar extension was the more common treatment. The overall response rate was 72.8% with completed response at 16.4%. Memory and intellectual sequelae were the most common late complications of treatment （14%）. The ten-year PFS was at 84.6%. PFS was found to be significantly better with higher dose of RT （up to 54 Gy）, treatment by both surgery and RT, absence of visual field defect, and tumor localized to sella, whereas it was not significantly affected by age and sex. CONCLUSION The data confirmed that the prevalence of mass effect and hypopituitarism in patients with non-functioning pituitary macroadenoma is elevated. Conventional external RT up to 54 Gy is safe and effective in controlling non-functioning pituitary macro- adenoma with tolerable and acceptable morbidity.
基金Project(2017yfc0602901)supported by the National Key R&D Program of China during the Thirteenth Five-Year Plan PeriodProject(2017zzts204)supported by the Fundamental Research Funds for the Central Universities of Central South University,China
文摘In order to overcome the limitation that rock mass instability warnings are caused by a lack of deep consideration of the inherent mechanism of disaster formation, early warning signs of rock mass instability were detected and multi-field coupling was analyzed. A multi-field coupling model of a damaged rock mass was established. The relationship between microseismic activity parameters and rock mass stability was analyzed, and a multi-parameter early warning index system was established and its solution program was compiled. Based on the D-S data fusion theory,an early warning model of rock mass instability combining multi-field coupling analysis and microseismic monitoring was constructed. Taking an underground mine stope as an object, the multi-field coupling model and its solution program were used to analyze mining response characteristics. The seismic field data were used to verify the accuracy of the multi-field coupling analysis. The early warning model was used to predict the instability of stope rock mass,and the early warning result is consistent with a real-world scenario.
文摘Modeling and validation of full power converter wind turbine models with field measurement data are rarely reported in papers. In this paper an aggregated generic dynamic model of the wind farm consisting of full power converter wind turbines is composed and the model validation based on actual field measurements is performed. The paper is based on the measurements obtained from the real short circuit test applied to connection point of observed wind farm. The presented approach for validating the composed model and fault ride-through （FRT） capability for the whole wind park is unique in overall practice and its significance and importance is described and analyzed.
文摘This study examines the effect of audit quality （AQ） on the earnings response coefficient （ERC） based on a sample of 1,884 firm-year observations comprising 471 firms listed on the Bursa Malaysia from 2007 to 2010. This study tests whether AQ affects ERC after controlling the established determinants of ERC： beta, growth, earnings persistence, and size. Using reverse regression, the study confirms that Big 4 is significant and positive to ERC. Auditor switching from non-Big 4 to Big 4 indicates the same results; however, the switching of auditors among Big 4 is not significant. The study thus provides systematic and comprehensive additional evidence on the effect of AQ via the measurement of Big 4; and auditor switching from non-Big 4 to Big 4 and switching among Big 4 on ERC. This is an important contribution to the literature but especially so given that the evidence comes from Malaysia, an emerging economy, whereas the existing empirical literature relates mainly to the developed countries.
文摘In order to provide power quality monitoring activities with metrological certification, a DAS （data acquisition system） has been designed, realized and characterized. The system allows acquisition on tri-phases plus neutral lines picking up 499 samples per period of the fundamental at 50 Hz. To ensure certified measurements, the system gets external certified time and voltage references. The system uses a FTDI Virtual Com Port Driver to communicate data over High Speed RS232 virtual interface and it does not need any advanced programming skill. The choice to use a virtual serial communication makes the data acquisition software portable over many platforms, regardless by the development environment and by the programming language. To test the proposed device some custom software have been written in many programming language （C^#, VB6, LabView, MatLab）, moreover in order to characterize the device the most common ADC （analog to digital converter） performing test have been applied.
文摘The large eddy simulation (LES) using the steady laminar flamelet model is applied to a simple turbulent jet flame with 33.2% H2,22.1% CH4 and 44.7% N2 at the Reynolds number of 15,200 in order to validate the numerical methods and to investigate the flame structure.For the validation,the detailed experimental data of DLR-A flame is used.The numerical results are in reasonable agreement with experimental results except mass fractions of minor species.In the flow field,the break-down of the potential core,the vortex structure and the mixing intensity are well captured.In the combustion field,mass fractions of major species (H2O,CO2,CO) are well predicted quantitatively.Minor species are well predicted qualitatively.In the present study,the simulations conducted on the Cartesian and cylindrical grids with approximately 6.6× 10 5 nodes are compared.
基金supported by the National Natural Science Foundation of China(Grant Nos.11522540,and 11690021)the Top-Notch Young Talents Program of China,and the Provincial Department of Education of Liaoning(Grant No.L2012087)
文摘In this paper, we consider the singular isothermal sphere lensing model that has a spherically symmetric power-law mass dis- tribution ρtot（r） - r-γ. We investigate whether the mass density power-law index y is cosmologically evolutionary by using the strong gravitational lensing （SGL） observation, in combination with other cosmological observations. We also check whether the constraint result of y is affected by the cosmological model, by considering several simple dynamical dark energy models. We find that the constraint on y is mainly decided by the SGL observation and independent of the cosmological model, and we find no evidence for the evolution of y from the SGL observation.
