AIM： To study the clinicopathological characteristics of unsuspected gallbladder carcinoma （UGC）. METHODS： We retrospectively studied 23 cases of UGC in Tongji Hospital, and compared their clinicopathological char...AIM： To study the clinicopathological characteristics of unsuspected gallbladder carcinoma （UGC）. METHODS： We retrospectively studied 23 cases of UGC in Tongji Hospital, and compared their clinicopathological characteristics with 33 cases of preoperatively diagnosed gallbladder carcinoma （PDGC）. RESULTS： The proportion of UGC coexisting with cholecystolithiasis was significantly higher than that of PDGC （x^2 = 13.53, P 〈 0.01）. The infection rate of hepatitis B virus was 21.74% （5/23） in UGC and 30.30% （10/33） in PDGC. Nine （39.13%） of 23 patients with UGC and 8/33 （24.24） PDGC had contact with schistosome pestilent water. The rate of multiple pregnancies was 56.52% （13/23） in the patients with UGC and 42.42% （14/33） in PDGC. The primary location of the UGC was mostly in the neck and body of the gallbladder, and that of the PDGC was often in the body and bottom. The incidence of Nevin stage I and 11 UGC was significantly higher than that of PDGC （x^2 = 4.44, P 〈 0.05 and 2 = 4.96, P 〈 0.05） while that of Nevin stage V UGC was significantly lower than that of PDGC （x^2 = 7.59, P 〈 0.01）. According to the grading of carcinoma, the incidence of well-differentiated UGC was significantly higher than that of PDGC （2 = 4.16, P 〈 0.05）, and that of poorlydifferentiated UGC was significantly lower than that of PDGC （x^2 = 4.48, P 〈 0.05）.CONCLUSION： There are different characteristics between UGC and PDGC, such as in primary location, malignant degree and incidence of coexistence with cholecystolithiasis. Cholecystolithiasis, hepatitis B, schistosome and multiple pregnancies were high risk factors for gallbladder carcinoma.展开更多
The rapid development in the field of optic in the past decade demonstrates a potential for cancer diagnosis using optical technologies. This review highlights the principle and advantages of using optical technologie...The rapid development in the field of optic in the past decade demonstrates a potential for cancer diagnosis using optical technologies. This review highlights the principle and advantages of using optical technologies, and focuses on their application in tumor diagnosis and their limitation in clinical uses. These optical technologies are rapid methods,which can provide a great deal of different information from conventional methods, while,it still requires clinical trial studies to develop and ensure the applicability of these optical technologies for clinical cancer diagnosis.展开更多
A novel method, based on acoustic emission (AE) techniques, for detecting agglomeration in fluidized beds is presented. Particle size characteristics are determined based on the principle that AE signals with differen...A novel method, based on acoustic emission (AE) techniques, for detecting agglomeration in fluidized beds is presented. Particle size characteristics are determined based on the principle that AE signals with different frequency band energies are emitted when particles of different sizes impact an internal wall. By applying chaotic analysis to the AE signals, the malfunction coefficients are well defined. Agglomeration in the fluidized bed can then be detected by the sudden variation of malfunction coefficients. AE signals were investigated in a laboratory scale heated fluidized bed and an industrial polyethylene fluidized bed. Experimental data showed that the malfunction coefficients increased with the growth of agglomeration. The results indicated that agglomeration in fluidized beds can be predicted and diagnosed effectively and precisely using AE techniques based on chaotic analysis.展开更多
文摘AIM： To study the clinicopathological characteristics of unsuspected gallbladder carcinoma （UGC）. METHODS： We retrospectively studied 23 cases of UGC in Tongji Hospital, and compared their clinicopathological characteristics with 33 cases of preoperatively diagnosed gallbladder carcinoma （PDGC）. RESULTS： The proportion of UGC coexisting with cholecystolithiasis was significantly higher than that of PDGC （x^2 = 13.53, P 〈 0.01）. The infection rate of hepatitis B virus was 21.74% （5/23） in UGC and 30.30% （10/33） in PDGC. Nine （39.13%） of 23 patients with UGC and 8/33 （24.24） PDGC had contact with schistosome pestilent water. The rate of multiple pregnancies was 56.52% （13/23） in the patients with UGC and 42.42% （14/33） in PDGC. The primary location of the UGC was mostly in the neck and body of the gallbladder, and that of the PDGC was often in the body and bottom. The incidence of Nevin stage I and 11 UGC was significantly higher than that of PDGC （x^2 = 4.44, P 〈 0.05 and 2 = 4.96, P 〈 0.05） while that of Nevin stage V UGC was significantly lower than that of PDGC （x^2 = 7.59, P 〈 0.01）. According to the grading of carcinoma, the incidence of well-differentiated UGC was significantly higher than that of PDGC （2 = 4.16, P 〈 0.05）, and that of poorlydifferentiated UGC was significantly lower than that of PDGC （x^2 = 4.48, P 〈 0.05）.CONCLUSION： There are different characteristics between UGC and PDGC, such as in primary location, malignant degree and incidence of coexistence with cholecystolithiasis. Cholecystolithiasis, hepatitis B, schistosome and multiple pregnancies were high risk factors for gallbladder carcinoma.
文摘The rapid development in the field of optic in the past decade demonstrates a potential for cancer diagnosis using optical technologies. This review highlights the principle and advantages of using optical technologies, and focuses on their application in tumor diagnosis and their limitation in clinical uses. These optical technologies are rapid methods,which can provide a great deal of different information from conventional methods, while,it still requires clinical trial studies to develop and ensure the applicability of these optical technologies for clinical cancer diagnosis.
基金Project supported by the National Natural Science Foundation of China (Nos. 20676114 and 20736011)the National Hi-Tech Research and Development Program (863) of China (No. 2007AA04Z182)
文摘A novel method, based on acoustic emission (AE) techniques, for detecting agglomeration in fluidized beds is presented. Particle size characteristics are determined based on the principle that AE signals with different frequency band energies are emitted when particles of different sizes impact an internal wall. By applying chaotic analysis to the AE signals, the malfunction coefficients are well defined. Agglomeration in the fluidized bed can then be detected by the sudden variation of malfunction coefficients. AE signals were investigated in a laboratory scale heated fluidized bed and an industrial polyethylene fluidized bed. Experimental data showed that the malfunction coefficients increased with the growth of agglomeration. The results indicated that agglomeration in fluidized beds can be predicted and diagnosed effectively and precisely using AE techniques based on chaotic analysis.
