AIM: To investigate the vasculature of rabbit liver metastatic lesions by color Doppler imaging and power Doppler imaging (PDI) techniques.METHODS: Eight New Zealand rabbits with implanted VX2 liver tumors were used. ...AIM: To investigate the vasculature of rabbit liver metastatic lesions by color Doppler imaging and power Doppler imaging (PDI) techniques.METHODS: Eight New Zealand rabbits with implanted VX2 liver tumors were used. All ultrasound examinations were performed with a HP 5500 color Doppler ultrasound scanner. Before and after the injection of contrast agent, the changes of gray scale and the periphery and intralesional blood flow of the liver metastatic lesion were carefully observed by B mode ultrasound, color Doppler flow imaging (CDFI)and PDI.RESULTS: Twelve lesions were found in the eight rabbits with implanted VX2 liver tumors, whose diameter rangedfrom 1.6 to 4.8 cm. Echoes of these lesions were not characterized and has lack of specificity. After the injectionof contrast agent, the numbers of dot or strip-like flow messages increased both at the periphery and inside of these lesions under the mode of CDFI and PDI, and were more pronounced under PDI. Morphology of intralesional vessels extended, even branched and some signals were clearly found encircling the lesion. And some vessels were found penetrating into the center of the lesion.CONCLUSION: PDI after injection of self-made echo contrast agent can show a pronounced sensitivity than that of B mode ultrasound and CDFI in diagnosis of vascularity of a metastatic lesion.展开更多
Three-dimensional medical image visualization becomes an essential part for medical field, including computer aided diagnosis, surgery planning and simulation, artificial limb surgery, radiotherapy planning, and teach...Three-dimensional medical image visualization becomes an essential part for medical field, including computer aided diagnosis, surgery planning and simulation, artificial limb surgery, radiotherapy planning, and teaching etc. In this paper, marching cubes algorithm is adopted to reconstruct the 3-D images for the CT image sequence in DICOM format under theVC＋＋6.0 and the visual package VTK platform. The relatively simple interactive operations such as rotation and transfer can be realized on the platform. Moreover, the normal vector and interior point are calculated to form the virtual clipping plane, which is then used to incise the 3-D object. Information of the virtual slice can be obtained, in the mean while the virtual slice images are displayed on the screen. The technique can realize the real time interaction extraction of virtual slice on 3-D CT image. The cuboids structured can be zoomed, moved and eircumrotated by operating mouse to incise the 3-D reconstruction object. Real time interaction can be realized by clipping the reconstruction object. The coordinates can be acquired by the mouse clicking in the 3D space, to realize the point mouse pick-up as well angle and distance interactive measurement. We can get quantitative information about 3-D images through measurement.展开更多
Visible Human Project (VHP)' was initiated by US National Library of Medicine in 1989, and in August 1991, the library signed a contract with Health Science Center of the University of Colorado to formally carry o...Visible Human Project (VHP)' was initiated by US National Library of Medicine in 1989, and in August 1991, the library signed a contract with Health Science Center of the University of Colorado to formally carry out the project. Accordingly, research team at the University of Colorado collected a structural data set of human body after obtaining successive sectional images. A digital image data set of a complete human male cadaver was acquired and made available for public use in November 1994, which aroused worldwide enthusiasm in this field, and remarkable social and economic benefit has been gained. Thereafter, some countries initiated their visible human project one after another. Korea started 5-year' Visible Korean Human (VKH)' project (Mar. 2000-Feb. 2005) in 2000, and the first data set derived from a patient with cerebroma was acquired in 2001. China began its project in 1999. The first data set of Chinese visible human was obtained at The Third Military Medical University in October 2002. Before that, by utilizing data made public by US VHP, Chinese scientists in informatics had exerted themselves on preliminary work to pave the way for further achievement. Now that VHP research is such a promising scientific field to meet the need of digital era and will be increasingly common in many areas related with structure and function of human body, the deployment of Chinese Visible Human Project (CVHP) is of great strategic significance with regard to science and technology.展开更多
基金Supported by the National Science Foundation of China,No.30070227the Foundation of the Chongqing Committee of Science and Technology,No.7446
文摘AIM: To investigate the vasculature of rabbit liver metastatic lesions by color Doppler imaging and power Doppler imaging (PDI) techniques.METHODS: Eight New Zealand rabbits with implanted VX2 liver tumors were used. All ultrasound examinations were performed with a HP 5500 color Doppler ultrasound scanner. Before and after the injection of contrast agent, the changes of gray scale and the periphery and intralesional blood flow of the liver metastatic lesion were carefully observed by B mode ultrasound, color Doppler flow imaging (CDFI)and PDI.RESULTS: Twelve lesions were found in the eight rabbits with implanted VX2 liver tumors, whose diameter rangedfrom 1.6 to 4.8 cm. Echoes of these lesions were not characterized and has lack of specificity. After the injectionof contrast agent, the numbers of dot or strip-like flow messages increased both at the periphery and inside of these lesions under the mode of CDFI and PDI, and were more pronounced under PDI. Morphology of intralesional vessels extended, even branched and some signals were clearly found encircling the lesion. And some vessels were found penetrating into the center of the lesion.CONCLUSION: PDI after injection of self-made echo contrast agent can show a pronounced sensitivity than that of B mode ultrasound and CDFI in diagnosis of vascularity of a metastatic lesion.
基金National 973 Basic Research Program of Chinagrant number:2010CB732600+4 种基金Major Research Equipment Fund of the Chinese Academy of Sciences and Knowledge Innovation Project of the Chinese Academy of Sciences,2008 Shenzhen Controversial Technology Innovation Research Projectsgrant number:FG200805230224AConcentration plan of innovation sources of Shenzhen-R&D projects of international cooperation on science and technologygrant number:ZYA200903260065ANatural Science Foundation of Guangdong Province,China 8478922035-X0007007
文摘Three-dimensional medical image visualization becomes an essential part for medical field, including computer aided diagnosis, surgery planning and simulation, artificial limb surgery, radiotherapy planning, and teaching etc. In this paper, marching cubes algorithm is adopted to reconstruct the 3-D images for the CT image sequence in DICOM format under theVC＋＋6.0 and the visual package VTK platform. The relatively simple interactive operations such as rotation and transfer can be realized on the platform. Moreover, the normal vector and interior point are calculated to form the virtual clipping plane, which is then used to incise the 3-D object. Information of the virtual slice can be obtained, in the mean while the virtual slice images are displayed on the screen. The technique can realize the real time interaction extraction of virtual slice on 3-D CT image. The cuboids structured can be zoomed, moved and eircumrotated by operating mouse to incise the 3-D reconstruction object. Real time interaction can be realized by clipping the reconstruction object. The coordinates can be acquired by the mouse clicking in the 3D space, to realize the point mouse pick-up as well angle and distance interactive measurement. We can get quantitative information about 3-D images through measurement.
文摘Visible Human Project (VHP)' was initiated by US National Library of Medicine in 1989, and in August 1991, the library signed a contract with Health Science Center of the University of Colorado to formally carry out the project. Accordingly, research team at the University of Colorado collected a structural data set of human body after obtaining successive sectional images. A digital image data set of a complete human male cadaver was acquired and made available for public use in November 1994, which aroused worldwide enthusiasm in this field, and remarkable social and economic benefit has been gained. Thereafter, some countries initiated their visible human project one after another. Korea started 5-year' Visible Korean Human (VKH)' project (Mar. 2000-Feb. 2005) in 2000, and the first data set derived from a patient with cerebroma was acquired in 2001. China began its project in 1999. The first data set of Chinese visible human was obtained at The Third Military Medical University in October 2002. Before that, by utilizing data made public by US VHP, Chinese scientists in informatics had exerted themselves on preliminary work to pave the way for further achievement. Now that VHP research is such a promising scientific field to meet the need of digital era and will be increasingly common in many areas related with structure and function of human body, the deployment of Chinese Visible Human Project (CVHP) is of great strategic significance with regard to science and technology.
