诊断性CT在^(18)F-FDGPET-CT在肿瘤显像中的临床价值

目的:探讨诊断性CT的扫描在18F-FDG PET/CT在肿瘤显像中的临床应用价值。方法:回顾性总结2005年10月~2007年7月的28例肿瘤患者(男性29例,女性19例,平均年龄56±10.5岁资料。所有患者均先行PET/CT显像后,根据PET/CT显像结果的不同,行诊断性CT(增强CT)检查。按PET显像后的不同结果分为3组,组1入选18例,PET/CT显像明确有肿瘤病灶,术前临床要求提供准确的肿瘤供血血管及与临近组织的关系。组2入选15例,为PET/CT显像阴性。组3入选15例患者,PET/CT显像阳性,但不能定性。结果:①组1的18例患者通过诊断性CT的CTA检查,全部明确了病灶的血供及其与周围组织的关系。②组2及组3的30例PET表现阴性或阳性患者的诊断问题通过CT的增强扫描均得到确定或更正。结论:诊断性CT扫描的应用可以弥补常规PET/CT检查中的某些不足,达到优势互补作用。

诊断性CT在^(18)F-FDG PET-CT检查中的应用

探讨诊断性CT的扫描在18F-FDG PET-CT中的应用价值。资料与方法:回顾性总结2005年10月-2005年12月,同时行PET/CT及诊断性CT检查的15例患者(男性12例,女性3例,平均年龄58岁)病例资料。结果:诊断性CT的扫描,15例行18F-FDG PET-CT的患者的诊断得到确定或更正。结论:诊断性CT扫描的应用可以弥补常规PET-CT检查中的某些不足,起到优势互补作用。

Capability of multidetector CT to diagnose hepatocellular carcinoma-associated arterioportal shunt

AIM: To investigate the capability of multidetector CT (MDCT) to diagnose HCC-associated arterioportal shunt (APS).METHODS: Two hundred and eighty-two patients with HCC received both thin-slice and enhancement MDCT scanning at early hepatic arterial phase, late hepatic arterial phase and portal venous phase, and digital subtract angiography (DSA) examination. Images were analyzed jointly by two experienced radiologists blinded to the opposite examination results, including the existence or not of APS, shunt locations, types and degrees of APS, with or without thrombosis. RESULTS: There were 56 APS associated with HCC, including 48 central, seven peripheral and one mixed, or 42 severe, seven moderate, seven mild APS. Fortyone severe, seven moderate and central APS were all revealed with MDCT and DSA. Seven mild and peripheral APS were all displayed with MDCT; only five of them displayed DSA, two faint shunt APS associated with massive HCC were missed. One mixed APS was demonstrated as severe combined with mild shunt with both MDCT and DSA.CONCLUSION: MDCT could diagnose not only DSA revealed APS, but also missed mild and peripheral APS with DSA due to faint shunt associated with massive HCC, is a simple, effective and noninvasive new technique for diagnosis of HCC-associated APS.

Evaluation of spiral CT imaging in the diagnosis of the primary ureteral carcinoma

Objective: To explore the characteristics of the primary ureteral carcinoma (PUC) and discuss the value of spiral CT (SCT) in the diagnosis of PUC. Methods: The SCT findings of the primary ureteral carcinoma in 16 cases were analyzed and compared with the histopathological diagnosis and staging. Results: The transverse diameters of the lesions were 1.0–2.1 cm, and the longitudinal lengths were 1.5–15.2 cm. There were no statistically significant differences (P>0.1) in diam- eters and lengths among the low staging group (pT0–T2) and the high staging group (pT3–T4). The average CT value of the lesions was 43 HU on plain scanning, and 73 HU on CE scanning. The increment was 30 HU. The lesions were clearer on CE scanning. Curved planar reconstruction (CPR) could show the entire course of the urinary tract. Among 6 cases of pT3 stage, CT gave a correct diagnosis in 1 case. For 2 cases of pT4 stage, CT gave correct diagnoses in both cases. Conclusion: The carcinomatous lesions spread along the ureter. The longitudinal length of each lesion is longer than its transverse diameter. Tumor cannot be staged merely according to its diameter and length. CT is difficult to differentiate stage T0–T3, while for stage T4, CT diagnosis is accurate. Contrast enhancement CT scanning has the confirming and differentiating roles. CPR offers direct and easy observing images for clinical doctors.

The value of MSCT in diagnosis of parotid benign tumor (An analysis of 84 cases)

Objective:The purpose of the study was to assess diagnostic performance of MSCT images in patients with parotid benign tumors and provide useful criteria for the characterization of their various pathological types preoperatively. Methods: Retrospectively analyzed clinical and imaging characteristics of 84 cases of pathologically confirmed primary parotid benign tumors. MSCT plain-scan and enhanced-scan were performed in all cases. After injection of 50 mL contrast material at a rate of 3.5 mL/s,spiral CT scans were obtained at arterial and venous phases with scanning delay of 30 s and 75 s,respectively. The attenuation change and enhancement patterns in the tumors were assessed. Quantitatively assess the increased CT number of the tumors in different enhanced-phases compared with the plain-scan and the ratio of increased CT number at venous phase scanning to that at arterial phase scanning also was calculated. Results:In all of 84 cases,40 cases were solitary pleomorphic adenomas,29 cases were adenolyphomas,6 cases were multiple tumors,2 cases were bilateral,15 cases were Basal cell tumor,and one of them had two small lesions. The diameter was 1–5 cm in most of cases,whose margin was smooth and clear,cystic changes in some cases. At two-phase scans,pleomorphic adenomas showed a pattern of slight enhancement and venous enhancement,adenolymphomas showed a pattern of strong enhancement at arterial phase scanning with a decrease at venous phase scanning,basal cell tumor showed a pattern of persistent strong enhancement with commonly significant cystic areas. The ratio of increased CT number was significant different between adenolymphomas and other pathological types. Conclusion: The evaluation of enhancement patterns at two-phase enhanced-scan MSCT is helpful in the differential diagnosis of parotid gland benign tumors.

螺旋CT多期增强扫描对肝癌的供血方式的分析及意义

目的:探讨肝癌螺旋CT多期增强扫描供血方式及诊断价值。材料与方法:回顾性分析47例经手术病理证实或临床确诊的原发性肝癌的CT资料。结果:47例中,小肝癌4例,结节型15例,巨块型23例,弥漫型5例。平扫43例呈低密度,4例等密度。密度均匀8例,密度不均匀39例。增强检查47例中,肝动脉供血37例,占78.7%,强化方式呈"速升速降"。其它供血方式10例,占21.3%。结论:螺旋CT多期增强扫描能获得肝癌的强化特征,对肝癌的诊断有着重要的价值。

Value of Multi-slice spiral CT in diagnosis of malignant gastrointestinal stromal tumors

Objective： The aim of this study was to investigate the value of multi-slice spiral CT （MSCT） in the diagnosis of malignant gastrointestinal stromal tumors （GISTs）. Methods： Twenty-seven cases of MSCT images of malignant GIST proved by surgery and pathology were retrospectively analyzed. Both plain and enhanced CT scan was performed and multiplanar reconstruction was made in all cases. Results： The lesions originated from the stomach （n = 11）, small intestine （n = 9）, colon （n = 4）, rectum （n = 1）, and mesentery （n = 2）. The transverse diameters of mass were 4.2-22 cm, the edges clearly （n = 12）, unclearly （n = 15）. The mass were mainly irregular in shape Iobulated （n = 19）. The lesions were mainly heterogeneity on plain scan, moderate to marked enhancement in arterial phase and durative enhanced in venous phase. Cystic necrosis were observed in all the lesions, 9 cases were cystic and solid mixed mass. Hepatic metastases （n = 4）, pulmonary metastasis （n = 1）, lymphatic metastasis （n = 2） were detected. The accuracy rate of MSCT diagnosis for location and pathologic features of GISTs were 85.2% （23/27） and 77.8% （21/27）. Conclusion： Two-phase MSCT examination and axial images combined with multiplanar reconstruction images have important value for diagnosis of malignant GIST.

Sub-acute disseminated pulmonary tuberculosis in a girl diagnosed by CT guided transthoracic needle biopsy: case report and literature review

Primary tuberculosis often occurs in children with the main types of hilar lymphonode tuberculosis or Ghon complex. When pulmonary tuberculosis aggravates and tubercule bacillus invades pulmonary veins, a disseminated disease may occur clinically. One 8-year-old girl presented with hypodynamia and emaciation. CT indicated the disseminated disease and extensive mediastinal and hilar lymphadenopathy. But she had negative sputum smears and negative PPD test. The bronchi showed inflammatory change in fiberoptic bronchoscopy. Percutaneous transthoracic needle biopsy (PTNB) guided by CT was used as a means for the diagnosis of pulmonary tuberculosis. The case was rapidly diagnosed as sub-acute disseminated pulmonary tuberculosis with the help of combined CT imagine and histology.

Analysis of 96 cases of solitary pulmonary nodule diagnosed by MSCT

Objective:The aim of this study was to explore the diagnostic value of multi-slice computer tomography(MSCT) in solitary pulmonary nodule(SPN).Methods:Contrastive analysis of the differences of CT signs between benign and malignant SPN.Results:The typical sign of pleural indentation was a reliable sign for lung cancers.Vacuole sign suggested lung cancer highly.Blood vessels cluster involving the vein alone had big opportunity to lung cancer.Type I tumor-bronchial relation was the most common relation in lung cancers.Type V tumor–bronchial relation was the most common relation in benign SPN.Conclusion:MSCT had a very high diagnostic value in SPN.

Colon Duplication Combined with Mature Teratoma-A Case Report

Gastrointestinal duplication is an uncommon congenital abnormality, and colonic duplication combined with teratoma has rarely been reported. A 24-year-old man presented to the Emergency Department with a sudden onset of severe abdominal pain lasting 2 hours without intermission, and also complained to have who had chronic constipation since his birth.Multislice CT imaging showed 2 masses in the retroperitoneal space. The one huge cystic mass was detected behind the transverse colon, pancrease and stomach without infiltration into the surrounding tissues. The right mass containing soft tissues and bones pushed aside the inferior vena cava and right kidney.The cystic duplication and the right mass were excised separately.This case indicates that a patient diagnosed as colonic duplication should receive further differential diagnosis to identify if it coexists other diseases, espedally the teratoma.

Value of multidetector spiral CT in diagnosis of acute thoracolumbar spinal fracture and fracture-dislocation

Objective: To investigate the diagnostic value of multidetector spiral CT (MSCT) in acute thoracolumbar spinal fracture and fracture-dislocation. Methods: CT imaging files of 152 consecutive traumatic patients with thoracolumbar fractures were retrospectively reviewed. MSCT scannings were performed with a collimation of 3-5 mm and a pitch of (5.5). The postprocessing included sagittal and coronal multiplannar reconstruction, and 3-D reconstruction.Results: There were 88 cases of compression fracture, 54 cases of burst fracture and 10 cases of fracture-dislocation. Transverse images of MSCT could visualize all fractures directly and determine whether spinal canal was intact. Postprocessing image was helpful in depicting the displacement of fragment and orientation of dislocation.Conclusions: MSCT plays an important role in diagnosis and management of acute thoracolumbar spinal fracture and fracture-dislocation.

Diagnostic accuracy of CT scan in abdominal blunt trauma

Objective： To evaluate the sensitivity and specificity of CT scan findings in patients with blunt abdominal trauma admitted to the university hospital. Methods： All the patients with blunt abdominal trauma admitted at a tertiary teaching trauma center in Iran between 2005 and 2007 were enrolled in this study. In the absence of any clinical manifestations, the patients underwent a diagnostic CT scan. Laparatomy was performed in those with positive CT results. Others were observed for 48 hours and discharged in case no problem was reported; otherwise they underwent laparatomy. Information on patients＇ demographic data, mechanism of trauma, indication for CT scan, CT scan findings, results of laparotomy were gathered. The sensitivity, specificity and accuracy of the CT-scan images in regard with the organ injured were calculated. The sensitivity, specificity and accuracy of the CT scan were calculated in each case. Results： CT scan had the highest sensitivity for detecting the injuries to liver （100%） and spleen （86.6%）. The specificity of the method for detecting retroperitoneal hematoma （100%） and injuries to kidney （93.5%） was higher than other organs. The accuracy of CT images to detect the injuries to spleen, liver, kidney and retroperitoneal hematoma was reported to be 96.1%, 94.4%, 91.6% and 91.6% respectively. Conclusion： The findings of the present study reveal that CT scan could be considered as a good choice, especially for patients with blunt abdominal trauma in teaching hospitals where the radiologic academic staff is not present in the hospital in the night shifts.

CT and MRI diagnosis of acute traumatic hepatic rupture:analysis of ten cases

In order to verify whether magnetic resonance imaging (MRI) is superior to computed tomography (CT) in the detection and characterization of intrahepatic hematoma in its acute stage, the MRI and CT features of acute traumatic hepatic rupture (ATHR) were retrospectively studied and compared. Methods: In the 10 cases of ATHR admitted to our institute, 3 were examined with CT, 1 with MRI and 6 with both CT and MRI in the first 24 hours post injury and 9 cases out of the 10 were checked up with MRI in the first week after injury of surgery. The shape of the traumatic lesions, the damages of the intrahepatic vessels and the severity of hepatic rupture displayed with CT and MRI were compared. Results: It was found that in the first 24 hours post injury, 66.6% of hepatic injuries were shown as hypointensity on T1 weighted images and low or high density on noncontrast CT. 100% of the lesions were identified as well marked hyperintensity on T2 weighted images. Damages of the hepatic and/or portal veins were observed in 7, 4 and 3 cases on T2 and T1 weighted images and noncontrast CT figures respectively. The severity of hepatic injuries were graded in 100%, 66.7% and 44.4%of cases with these 3 procedures respectively. Conclusions: On the basis of our findings, it is concluded that T2 weighted MRI is a more sensitive and reliable imaging modality in the detection and differentiation of the type and severity of acute hepatic rupture than T1 weighted imaging and noncontrast CT.

New scoring system for intra-abdominal injury diagno- sis after blunt trauma

Objective： An accurate scoring system for intra-abdominal injury （IAI） based on clinical manifesta- tion and examination may decrease unnecessary CT scans, save time, and reduce healthcare cost. This study is de- signed to provide a new scoring system for a better diagno- sis of IAI after blunt trauma. Methods： This prospective observational study was performed from April 2011 to October 2012 on patients aged above 18 years and suspected with blunt abdominal trauma （BAT） admitted to the emergency department （ED） of Imam Hussein Hospital and Shohadaye Hafte Tir Hospital. All patients were assessed and treated based on Advanced Trauma Life Support and ED protocol. Diagnosis was done according to CT scan findings, which was considered as the gold standard. Data were gathered based on patient＇s history, physical exam, ultrasound and CT scan findings by a general practitioner who was not blind to this study. Chi- square test and logistic regression were done. Factors with significant relationship with CT scan were imported in multi- variate regression models, where a coefficient （13） was given based on the contribution of each of them. Scoring systemwas developed based on the obtained total [3 of each factor. Results： Altogether 261 patients （80.1% male） were enrolled （48 cases of IAI）. A 24-point blunt abdominal trauma scoring system （BATSS） was developed. Patients were di- vided into three groups including low （score〈8）, moderate （8≤score〈12） and high risk （score≥ 12）. In high risk group immediate laparotomy should be done, moderate group needs further assessments, and low risk group should be kept under observation. Low risk patients did not show positive CT-scans （specificity 100%）. Conversely, all high risk patients had positive CT-scan findings （sensitivity 100%）. The receiver operating characteristic curve indicated a close relationship between the results of CT scan and BATSS （sensitivity=99.3%）. Conclusion： The present scoring system furnishes a high precision and reproducible diagnostic tool for BAT detection and has the potential to reduce unnecessary CT scan and cut unnecessary costs.