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肾活检病理诊断辅助系统的研究
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作者 陶瑜 钟觉民 +3 位作者 吴义芳 吴惠群 董愉 赖英荣 《现代医学仪器与应用》 2003年第3期1-3,共3页
微机处理肾活检病理诊断辅助系统选择并贮存了一般临床资料、病理形态学和免疫荧光检查等资料,通过多元分析,对照数据库中各种诊断分类的权值,提出一种或几种诊断供病理医师作诊断决策.诊断系数是我们首次提出的代表诊断可靠程度的概念.
关键词 肾活检 病理诊断 辅助系统 病理学 计算机 诊断系数
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基于扩展故障树的运载火箭故障诊断专家系统 被引量:18
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作者 刘成瑞 张庆振 任章 《宇航学报》 EI CAS CSCD 北大核心 2008年第6期1936-1941,共6页
针对运载火箭故障诊断专家系统中知识获取的瓶颈问题,通过将扩展故障树分析法和基于规则的诊断专家系统有机结合,建立基于扩展故障树的运载火箭故障知识获取及表示方法,实现了从扩展故障树到诊断知识的自动转换和诊断知识的规范化表示,... 针对运载火箭故障诊断专家系统中知识获取的瓶颈问题,通过将扩展故障树分析法和基于规则的诊断专家系统有机结合,建立基于扩展故障树的运载火箭故障知识获取及表示方法,实现了从扩展故障树到诊断知识的自动转换和诊断知识的规范化表示,解决了基于规则的诊断专家系统的知识获取难题。在此基础上,结合扩展故障树给出了运载火箭故障诊断专家系统快速推理策略。该策略基于诊断优先系数,实现了对发生概率大、结构重要度高、危害严重的故障的优先诊断,并通过浅层推理与深层推理相结合,保证了推理过程的精确性和严密性。 展开更多
关键词 运载火箭 故障诊断 扩展故障树 知识获取 诊断优先系数 推理机制
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基于信息熵的系统诊断参数交互推理选择方法
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作者 王朝辉 高澜庆 +1 位作者 石博强 吴玲娥 《北京科技大学学报》 EI CAS CSCD 北大核心 1995年第1期31-35,共5页
介绍了一种多输入、多输出系统的故障诊断参数选择方法,该方法以可观参数集的信息熵为标准,进行启发性诊断参数集的划分,先以系统状态决定的启发性诊断多数子集作为驱动数据,实施正向推理,缩小目标集合;再以故障目标集合为对象,... 介绍了一种多输入、多输出系统的故障诊断参数选择方法,该方法以可观参数集的信息熵为标准,进行启发性诊断参数集的划分,先以系统状态决定的启发性诊断多数子集作为驱动数据,实施正向推理,缩小目标集合;再以故障目标集合为对象,进行反向推理以确定最终故障集合;最后将故障集合的元素所对应的可测诊断参数作为系统的诊断参数进行测量。该方法构成了诊断型专家系统的一子部分。 展开更多
关键词 故障诊断 信息熵 推理 诊断系数 传感器
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肺癌血清标志物在健康体检中的价值分析 被引量:6
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作者 王靖妍 尹扬 赵知明 《癌症进展》 2018年第1期110-112,119,共4页
目的研究鳞状细胞癌相关抗原(SCC)、神经元特异性烯醇化酶(NSE)、癌胚抗原(CEA)及细胞角蛋白19片段(Cyfra21-1)4种肿瘤标志物筛查肺癌的价值及成本,探讨适合健康人群肺癌筛查的方法。方法回顾性分析进行健康体检的25 744位体检者的资料... 目的研究鳞状细胞癌相关抗原(SCC)、神经元特异性烯醇化酶(NSE)、癌胚抗原(CEA)及细胞角蛋白19片段(Cyfra21-1)4种肿瘤标志物筛查肺癌的价值及成本,探讨适合健康人群肺癌筛查的方法。方法回顾性分析进行健康体检的25 744位体检者的资料。统计不同项目联合检查方案对肺癌的检出率和早期检出率(简称早检率),对比同期门诊肺癌检出率,选择合适的筛查组合。计算发现肺癌和早期肺癌的费用及不同年龄段的肺癌检出费用。对比全国人均国内生产总值(GDP)和黑龙江人均GDP,通过计算早期诊断花费系数(EDCI)探讨筛查方法的价值。结果 "SCC+NSE+CEA+Cyfra21-1"联合筛查肺癌检出率为119/10万,早检率为77.4%,明显高于同期门诊肺癌的早检率(21.17%),差异有统计学意义(χ2=48.095,P﹤0.01)。每例肺癌的发现成本为224 761元,每例早期肺癌的发现成本为290 316元。以全国人均GDP计算EDCI为6.40,以黑龙江省人均GDP计算EDCI为7.64。以黑龙江人均GDP计算,55岁及以下体检者EDCI(21.13)是55岁以上者(4.08)的5.18倍。以全国人均GDP计算,55岁以上体检者EDCI仅为3.42。结论 "SCC+NSE+CEA+Cyfra21-1"联合筛查肺癌检出率和早检率较高,成本尚可接受,通过选择高危人群,可以进一步提高筛查效率,降低筛查成本。 展开更多
关键词 肺癌筛查 血清肿瘤标志物 早期诊断花费系数 价值分析
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Application of data fusion method to fault diagnosis of nuclear power plant 被引量:3
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作者 XIEChun-li XIAHong LIUYong-kuo 《Journal of Marine Science and Application》 2005年第1期30-33,共4页
The work condition of nuclear power plant (NPP) is very bad, which makes ithas faults easily. In order to diagnose (he faults real time, the fusion diagnosis system is built.The data fusion fault diagnosis system adop... The work condition of nuclear power plant (NPP) is very bad, which makes ithas faults easily. In order to diagnose (he faults real time, the fusion diagnosis system is built.The data fusion fault diagnosis system adopts data fusion method and divides the fault diagnosisinto three levels, which are data fusion level, feature level and decision level. The feature leveluses three parallel neural networks whose structures are the same. The purpose of using neuralnetworks is mainly to get basic probability assignment ( BPA) of D-S evidence theory, and the neuralnetworks in feature level are used for local diagnosis. D-S evidence theory is adopted to integratethe local diagnosis results in decision level. The reactor coolant system is the study object andwe choose 2# steam generator U-tubes break of the reactor coolant system as a diagnostic example.The experiments prove that the fusion diagnosis system can satisfy the fault diagnosis requirementof complicated system, and verify that the fusion fault diagnosis system can realize the faultdiagnosis of NPP on line timely. 展开更多
关键词 neural network D-S evidence theory fusion diagnosis system
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A NUMERICAL DIAGNOSIS OF LEADING SIGNALS FACILITATING A “NORTH-RIDGE SOUTH-TROUGH” DIPOLE FOR THE EARLY-2008 SOUTH-CHINA FREEZING-RAIN EVENTS 被引量:1
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作者 吴俊杰 林良勋 +2 位作者 钱钰坤 袁卓建 戚锦典 《Journal of Tropical Meteorology》 SCIE 2011年第2期93-102,共10页
Previous studies emphasize the important role of a "north-ridge versus south-trough" dipole (affecting the latitudes from 20° to 75° N around the Tibetan Plateau) of anomalous geopotential height (... Previous studies emphasize the important role of a "north-ridge versus south-trough" dipole (affecting the latitudes from 20° to 75° N around the Tibetan Plateau) of anomalous geopotential height ( Z ) in the early-2008 abnormal cryogenic freezing-rain-and-snow events in the southern part of China. The present study intends to extract the leading signal facilitating the dipole based on the numerical outputs of a full Z-linear model for diagnosing the global Z . Using this model built on full primitive equations in spherical-isobaric coordinates, we can further split the anomaly of Z-Zfζ-uβ (representing the Z component not explicitly associated with the Coriolis parameter f and its meridional derivative β ) into 15 components. With the model-output Zfζ-uβ (mainly accounting for the dipole under the geostrophic balance) and Z-Zfζ-uβ matrices as the left and right singular vectors respectively, a maximum covariance analysis (MCA) is performed to extract the significant 2-4-day leading signal carried by the MCA Z-Zfζ-uβ mode in the upstream area of the dipole. This leading signal is mainly attributed to 1) the abnormally strong westerlies centered around the exit region of the Atlantic jet-stream and 2) the corresponding anomalous 950-300 hPa anticyclone to the south of the abnormally strong center of westerlies. The energy of the positive wave center around this jet exit region favors the downstream north-ridge while the energy of the negative wave center associated with the anomalous anticyclone favors the downstream south-trough. 展开更多
关键词 blocking system freezing rain numerical diagnosis leading signals
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Usefulness of DWI in the evaluation of pulmonary isolated lesions 被引量:1
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作者 Zhiyong Li Tingting Zhang Bin Xu Qiang Wei Rui Han Wei Liu Jianlin Wu 《The Chinese-German Journal of Clinical Oncology》 CAS 2010年第7期388-390,共3页
Objective: The aim of our study was to investigate the value of Diffusion-weighted MR imaging (DWl) for evaluating differential diagnosis of pulmonary isolated lesions. Methods: Twenty-seven consecutive patients e... Objective: The aim of our study was to investigate the value of Diffusion-weighted MR imaging (DWl) for evaluating differential diagnosis of pulmonary isolated lesions. Methods: Twenty-seven consecutive patients enrolled in this study, all of whom underwent single direction DWl examinations and received a histologic and clinical diagnosis. Diffusion factor B value was 300, 500, 800 s/mm2, respectively. DWl images of twenty cases could be satisfied to measurement and diagnosis and success rate was percent 74. Among these, lung tuberculoma 5 cases, harmatoma 3 cases, peripheral lung cancer 12 cases. The apparent diffusion coefficient (ADC) values of the lesions were measured. Statistical analyses were performed with the independent samples t test for comparing difference of ADC values between malignant nodules and benign nodules at different 8 value. Results: DWI images of twenty cases could be satisfied and its success rate was percent 74. When B value was 300 s/mm2, ADC values of malignant nodules and benign nodules were 0.002192±0.0006091 mm2/s, 0.002454 ± 0.0007892 mm2/s, respectively, and P = 0.442. When B value was 500 s/mm2, ADC value of malignant nodules and benign nodules were 0.002065 ± 0.0006769 mm2/s, 0.002871± 0.0007746 mm2/s, respectively, and P = 0.033. When B value was 800 s/mm2, ADC value of malignant nodules and benign nodules were 0.001646 ± 0.0004292 mm2/s, 0.002651 + 0.0008041 mm2/s, respectively, and P = 0.009. There were the most different between malignant nodules and benign nodules at B value 800 and statistical significance. Conclusion: Lung DWl imaging is helpful to diagnosis and differential diagnosis between malignant and benign isolated nodules. The ADC value of benign lesions was statistically higher than that of malignant tumors. 展开更多
关键词 diffusion imaging NEOPLASM diagnosis
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