鸡白血病诊疗诊断治疗研究

近些年,我国蛋鸡养殖业的发展深受鸡白血病的影响。本文以鸡白血病诊疗诊断治疗为题,通过临床观察和解剖等方式,对鸡白血病进行诊断,并在此基础上,提出治疗病鸡的措施,希望为相关行业提供借鉴。

牦牛养殖中寄生虫病诊断与诊疗

牦牛作为高原地区的重要家畜资源,其健康状况对当地畜牧业发展至关重要。然而,寄生虫病是牦牛常见的疾病之一,严重影响牦牛的生长发育和生产性能。本文探讨了牦牛养殖中寄生虫病诊断与诊疗中存在的问题,并提出了相应的改进措施。首先,诊断方法不规范、手段落后以及忽视早期诊断是当前面临的主要问题。其次,治疗药物选择不当、治疗方案不合理以及预防控制措施不到位也制约了寄生虫病的有效控制。为了改善这一状况,需要规范诊断方法,引进先进诊断设备,加强早期诊断;合理使用治疗药物,制定科学的药物使用指南;制定综合治疗方案,结合药物治疗、物理治疗和免疫治疗等手段;强化预防控制措施,如定期驱虫、改善饲养环境等。

In vitro Degradation Study of a Braided Thin-Walled Biodegradable Ureteral Stent

The main disadvantage of conventional ureteral stents commonly used to provide urinary drainage after urological practice is that the patients have to undergo a secondary surgical procedure to remove stents. A new braided thin-walled biodegradable ureteral stent composed of PGA （ polyglycolic acid） and PLGA （ eopolymer of polylactic and polygiycolic acid） mnltifilaments was evaluated in v/tro in this study. In vitro degradation was performed in artificial urine with pH of 5.8 and the temperature of 37~C. The mass loss, mechanical properties, and morphology were observed at different degradaing time intervals of 0, 1, 2, 3, 4, and 5 weeks. The stent had a thinner wail than those of other degradable stents and provided better mechanical properties. The braided thin-walled biodegradable ureteral stents began to degrade after 2 weeks. At the week of 5, the stents were fully degraded. The degradative process of stents is smooth and well controlled.

Intrapancreatic accessory spleen:A case report and review of the literature

Here,we report a case of intrapancreatic accessory spleen confirmed by pathologic diagnosis and discuss its differential diagnosis and surgical management with a review of the literature.

Recent Progresses in Analysis of Tongue Manifestation for Traditional Chinese Medicine

Tongue diagnosis is one of the most precious and widely used diagnostic methods in Traditional Chinese Medicine (TCM). However, due to its subjective, qualitative and experience-dependent nature, the studies on tongue characterization have been widely emphasized. This paper surveys recent progresses in analysis of tongue manifestation. These new developments include the cross-network and cross-media color reproduction of tongue image, the automatic segmentation of tongue body based on knowledge, the automatic analysis of curdiness and griminess for the tongue fur and the automatic analysis of plumpness, wryness and dot -thorn of tongue body. The clinic experiments verify the validity of these new methods.

Synchronous Multiple Primary Gastric Carcinomas： A Case Report

IntroductionCarcinomas of the stomach are the most common malignant tumors in China. Due to the recent developments in diagnostic techniques and instrumentation, the early detection of gastric carcinoma （GC） has increased. Yet synchronous multiple primary gastric carcinomas, de- fined as 2 or more primary gastric carcinomas occurring in 1 patient simultaneously, are not frequently seen. The etiology of synchronous tumors is still unclear, and their coexistence can be problematic for surgeons, oncologists and pathologists in regards to diagnosis, treat- ment, and follow-up. Research has focused mainly on such issues as the frequency of occurrence of primary multiple carcinomas, identi- fication of high-risk groups, early diagnosis, treatment methods, and prognostic factors. The purpose of this article is to present a rare case of synchronous tumors and to review the literature addressing the surgical treatment for patients with multiple cancers.

Preoperative diagnosis of renal oncocytoma: case report and literature review

To differentiate renal oncocytoma from renal carcinoma, the clinical data of four patients with incidentally found renal oncocytomas were studied in this report. And additional Immunohistochemistry examinations were done to confirm diagnosis. Renal oncocytomas were found incidentally in four patients during medical examination. No characteristic changes were found in laboratory tests. Radiology examination provided the location and possibility of renal oncocytoma. History, laboratory test and radiology exanimation indicated the diagnosis of renal oncocytoma, but the final identify of renal oncocytoma need pathology examination.

Local resection for tumor of papilla of Vater: an analysis of 25 cases

Objective: To investigate the clinical features, diagnostic methods, and treatment choice of tumor of the papilla of Vater. Methods: The clinical data of 25 patients with tumor of the papilla of Vater treated by local resection in our hospital from December 1983 to May 2006 were retrospectively analyzed. Results: The morbidities of abdominal pain, jaundice and recurrent cholangitis were 84%, 80% and 48%, respectively. The accordant rate for preoperative duodenoscopic biopsy and post-operative pathological diagnosis was 80%. Intraoperative frozen section examination accurately predicted the final pathological results in all the patients. The post-operative complication rate was 20% and the operative mortality rate was 4%. The 5-year survival rates of local resection for benign tumors and malignant tumors were 75% and 28.5%, respectively. Conclusion: Abdominal pain, jaundice and recurrent cholangitis are the main symptoms and signs of tumor of the papilla of Vater. Duodenoscopy is the principal preoperative diagnostic method and intraoperative frozen section examination is reliable in assessing the operative specimens. Selective local resection is an effective treatment option for tumor of the papilla of Vater.

儿童抽动障碍中医临床诊疗规范探讨

参照国内外的相关研究，结合本课题组的研究成果，本文从儿童抽动障碍的诊断、辨证、规范治疗等方面探讨中医临床诊疗规范；以期为中医规范化治疗儿童抽动障碍提供参考。

Determination of specific IgG4 for diagnosis and therapeutic evaluation of cerebral cysticercosis

OBJECTIVE: To probe the significance of specific IgG4 in sera of patients with cerebral cysticercosis for diagnosis and therapeutic evaluation. METHODS: Specific IgG4 in sera of patients with cerebral cysticercosis was assessed using colloidal gold-labeled mouse-anti-human IgG4 McAb as probe. The results were compared with the CT image manifestation. RESULTS: The specific IgG4 positive rate in sera of patients with cerebral cysticercosis was 97.8%, whereas sera from patients with other kinds of parasitosis or central nerve system disease and the control group were all negative, except for a weak cross-reaction of sera from patients with hepatic echinococoosis. The determination of specific IgG4 in sera of patients with cerebral cysticercosis during different times of treatment showed that along with an increase in treatment time and improvement of clinical symptoms, specific IgG4 level gradually decreased. The positive rate and intensity of specific IgG4 in sera from patients with cerebral cysticercosis were consistent with the number of cysticercus parasites in the brain and pathologic changes, such as survival, disintegration, death and calcification. Survival of cysticercus in the brain was objectively evaluated using this technique. CONCLUSIONS: The determination of specific IgG4 in sera is a practical method for diagnosis and therapeutic evaluation of cerebral cysticercosis.

Supramolecular dendritic polymers for diagnostic and theranostic applications

Supramolecular dendritic polymers（SDPs）provide a new opportunity for the precision diagnosis and treatment of diseases. SDPs are a novel class of non-covalently bonded macromolecules with highly branched structure and three-dimensional globular topology, which exhibit dynamic/reversible features and unique physical/chemical properties（e.g., high solubility, low viscosity, and numerous functional terminal groups）. The reversibility of non-covalent interactions endows SDPs with the ability of facile preparation, smart responsiveness, and simple metabolism. These special characteristics determine the properties of SDPs, which are the key points for theranostic applications, including diagnosis,therapy, and theranostics. In this review, we briefly summarize the design and synthesis of SDPs with aimed structures,properties, functions as well as their present diagnostic and theranostic applications. These developments on the preparation and applications of SDPs for diagnostic and theranostic purpose promote interdisciplinary research fields of chemistry, material and biomedical science.

Recent therapeutic applications of the theranostic principle with dendrimers in oncology

At the intersection between treatment and diagnosis, nanoparticles technologies are strongly impacting the development of both therapeutic and diagnostic agents.Consequently, the development of novel modalities for concomitant noninvasive therapy and diagnostics known as theranostics as a single platform has gained significant interests. These multifunctional theranostic platforms include carbon-based nanomaterials（e.g., carbon nanotubes）, drug conjugates, aliphatic polymers, micelles, vesicles, core-shell nanoparticles, microbubbles and dendrimers bearing different contrast agents and drugs, such as cytotoxic compounds in the oncology domain. Dendrimers emerged as a new class of highly tunable hyperbranched polymers, and have been developed as useful theranostic platforms. Magnetic resonance imaging, gamma scintigraphy, computed tomography and optical imaging are the main techniques developed with dendrimers in the theranostic domain in oncology. Different imaging agents have been used such as Gd（Ⅲ）,19F, Fe2O3（MRI）,76Br（PET）,111In,88Y,153Gd,188Re,131I（SPECT）,177Lu,gold（CT） and boronated groups, siliconnaphthalocyanines,dialkylcarbocyanines and QDs（optical imaging dyes）.