The problems including excessive flow of attemperating water for boiler, failure of butterfly valve at the outlet of circulating water pump, burnt-out of thyristor for excitation regulator, load variation rate of CCS ...The problems including excessive flow of attemperating water for boiler, failure of butterfly valve at the outlet of circulating water pump, burnt-out of thyristor for excitation regulator, load variation rate of CCS not complying with the contract target, etc. occurred during start-up and debugging of two 600 MW generating units in Yangzhou No.2 Thermal Power Plant. Through analysis on these problems. the remedial measures were put forward, to which can be referred for similar units.展开更多
AIM: To clarify the role of high in normal-1 (HIN-1) gene promoter methylation during gastric cancer development. METHODS: Gastric cancer cell lines and tissue specimens were analyzed for expression of HIN-1 mRNA and ...AIM: To clarify the role of high in normal-1 (HIN-1) gene promoter methylation during gastric cancer development. METHODS: Gastric cancer cell lines and tissue specimens were analyzed for expression of HIN-1 mRNA and protein using the semi-quantitative reverse transcription polymerase chain reaction and immunohistochemistry. The methylation of the HIN-1 gene promoter was detected in gastric carcinoma cells and tissues using methylation-specific polymerase chain reaction. The 3-(4,5-dimethylthiazol-2yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium cell viability assay and flow cytometry were used to assess the changes in behaviors of gastric cancer cells with or without 5-aza-2’-deoxycytidine treatment. RESULTS: HIN-1 was not expressed in 4 of 5 gastric cancer cell lines. The demethylation reagent 5-aza-2’-deoxycytidine was able to induce or upregulate HIN-1 expression in gastric cancer cell lines, which is associated with reduction of tumor cell viability. Furthermore, methylation of the HIN-1 gene promoter was shown in 57.8% (26/45) of the primary gastric cancer and 42.1% (17/38) of adjacent tissue samples, but was not shown in normal gastric mucosa (0/10). From the clinicopathological data of the patients, methylation of the HIN-1 gene promoter was found to be associated with tumor differentiation (P = 0.000). CONCLUSION: High methylation of HIN-1 gene promoter results in silence of HIN-1 expression in gastric cancer. 5-aza-2’-deoxycytidine reverses HIN-1 methylation and reduces viability of gastric cancer cells.展开更多
Debris flow is one of the major secondary mountain hazards following the earthquake. This study explores the dynamic initiation mechanism of debris flows based on the strength reduction of soils through static and dyn...Debris flow is one of the major secondary mountain hazards following the earthquake. This study explores the dynamic initiation mechanism of debris flows based on the strength reduction of soils through static and dynamic triaxial tests. A series of static and dynamic triaxial tests were conducted on samples in the lab. The samples were prepared according to different grain size distribution, degree of saturation and earthquake magnitudes. The relations of dynamic shear strength, degree of saturation, and number of cycles are summarized through analyzing experimental results. The findings show that the gravelly soil with a wide and continuous gradation has a critical degree of saturation of approximately 87%, above which debris flows will be triggered by rainfall, while the debris flow will be triggered at a critical degree of saturation of about 73% under the effect of rainfall and earthquake(M>6.5). Debris flow initiation is developed in the humidification process, and the earthquake provides energy for triggering debris flows. Debris flows are more likely to be triggered at the relatively low saturation under dynamic loading than under static loading. The resistance of debris flow triggering relies more on internal frication angle than soil cohesion under the effect of rainfall and earthquake. The conclusions provide an experimental analysis method for dynamic initiation mechanism of debris flows.展开更多
Uniform seed spacing is considered a fundamental factor in quality and yield for many crops and drill manufacturers continuously try to improve the accuracy in seed placement, according to the cultivation standard req...Uniform seed spacing is considered a fundamental factor in quality and yield for many crops and drill manufacturers continuously try to improve the accuracy in seed placement, according to the cultivation standard requirements. This paper reports the results of tests on the performances of a six row pneumatic precision drill in which the depression into each sowing unit is created by means of flexible pipes that do not start directly from the fan, as in most pneumatic drills, but from an air duct having the function of uniformly distributing the air flow along the working width. Field tests have been conducted, using three graded seeds, to evaluate the accuracy of the single seed metering system, according to ISO 7256/1 standard, and the uniformity of negative pressure, through the measurement of the distance between seeds in the furrow, under two speed conditions （5 and 8 km bl）.展开更多
A rack cooling system based on a large scale flat plate pulsating heat pipe is proposed. The heat generated from IT equipment in a closed rack is transferred by the rear door pulsating heat pipe to the chilled air pas...A rack cooling system based on a large scale flat plate pulsating heat pipe is proposed. The heat generated from IT equipment in a closed rack is transferred by the rear door pulsating heat pipe to the chilled air passage and is avoided to release into the room. The influence of the start-up performance of the heat pipe, the load of the rack and the load dissipation to the temperature and the velocity distribution in the rack are discussed. It is found that the temperature would be lower and the temperature distribution would be more uniform in the rack when the pulsating heat pipe is in operation. Also, the effect of rack electricity load on temperature distribution is analyzed. It is indicated that higher velocity of chilled air will improve heat transfer of the rack.展开更多
文摘The problems including excessive flow of attemperating water for boiler, failure of butterfly valve at the outlet of circulating water pump, burnt-out of thyristor for excitation regulator, load variation rate of CCS not complying with the contract target, etc. occurred during start-up and debugging of two 600 MW generating units in Yangzhou No.2 Thermal Power Plant. Through analysis on these problems. the remedial measures were put forward, to which can be referred for similar units.
基金Supported by National Basic Research Program (973 Program No. 2010CB912802)the Postdoctoral Fund of China, No. 20080441314
文摘AIM: To clarify the role of high in normal-1 (HIN-1) gene promoter methylation during gastric cancer development. METHODS: Gastric cancer cell lines and tissue specimens were analyzed for expression of HIN-1 mRNA and protein using the semi-quantitative reverse transcription polymerase chain reaction and immunohistochemistry. The methylation of the HIN-1 gene promoter was detected in gastric carcinoma cells and tissues using methylation-specific polymerase chain reaction. The 3-(4,5-dimethylthiazol-2yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium cell viability assay and flow cytometry were used to assess the changes in behaviors of gastric cancer cells with or without 5-aza-2’-deoxycytidine treatment. RESULTS: HIN-1 was not expressed in 4 of 5 gastric cancer cell lines. The demethylation reagent 5-aza-2’-deoxycytidine was able to induce or upregulate HIN-1 expression in gastric cancer cell lines, which is associated with reduction of tumor cell viability. Furthermore, methylation of the HIN-1 gene promoter was shown in 57.8% (26/45) of the primary gastric cancer and 42.1% (17/38) of adjacent tissue samples, but was not shown in normal gastric mucosa (0/10). From the clinicopathological data of the patients, methylation of the HIN-1 gene promoter was found to be associated with tumor differentiation (P = 0.000). CONCLUSION: High methylation of HIN-1 gene promoter results in silence of HIN-1 expression in gastric cancer. 5-aza-2’-deoxycytidine reverses HIN-1 methylation and reduces viability of gastric cancer cells.
基金sponsored by Natural Science Foundation of China (Grant No. 51269012)Major Projects of Natural Science Foundation of Inner Mongolia Autonomous Region (Grant No. ZD0602)+2 种基金part of National Project 973 "Wenchuan Earthquake Mountain Hazards Formation Mechanism and Risk Control" (Grant No. 2008CB425800)funded by "New Century Excellent Talents" of University of Ministry of Education of China (Grant No. NCET-11-1016)China Scholarship Council
文摘Debris flow is one of the major secondary mountain hazards following the earthquake. This study explores the dynamic initiation mechanism of debris flows based on the strength reduction of soils through static and dynamic triaxial tests. A series of static and dynamic triaxial tests were conducted on samples in the lab. The samples were prepared according to different grain size distribution, degree of saturation and earthquake magnitudes. The relations of dynamic shear strength, degree of saturation, and number of cycles are summarized through analyzing experimental results. The findings show that the gravelly soil with a wide and continuous gradation has a critical degree of saturation of approximately 87%, above which debris flows will be triggered by rainfall, while the debris flow will be triggered at a critical degree of saturation of about 73% under the effect of rainfall and earthquake(M>6.5). Debris flow initiation is developed in the humidification process, and the earthquake provides energy for triggering debris flows. Debris flows are more likely to be triggered at the relatively low saturation under dynamic loading than under static loading. The resistance of debris flow triggering relies more on internal frication angle than soil cohesion under the effect of rainfall and earthquake. The conclusions provide an experimental analysis method for dynamic initiation mechanism of debris flows.
文摘Uniform seed spacing is considered a fundamental factor in quality and yield for many crops and drill manufacturers continuously try to improve the accuracy in seed placement, according to the cultivation standard requirements. This paper reports the results of tests on the performances of a six row pneumatic precision drill in which the depression into each sowing unit is created by means of flexible pipes that do not start directly from the fan, as in most pneumatic drills, but from an air duct having the function of uniformly distributing the air flow along the working width. Field tests have been conducted, using three graded seeds, to evaluate the accuracy of the single seed metering system, according to ISO 7256/1 standard, and the uniformity of negative pressure, through the measurement of the distance between seeds in the furrow, under two speed conditions （5 and 8 km bl）.
基金supported by National Natural Science Foundation of China(No.51376019)
文摘A rack cooling system based on a large scale flat plate pulsating heat pipe is proposed. The heat generated from IT equipment in a closed rack is transferred by the rear door pulsating heat pipe to the chilled air passage and is avoided to release into the room. The influence of the start-up performance of the heat pipe, the load of the rack and the load dissipation to the temperature and the velocity distribution in the rack are discussed. It is found that the temperature would be lower and the temperature distribution would be more uniform in the rack when the pulsating heat pipe is in operation. Also, the effect of rack electricity load on temperature distribution is analyzed. It is indicated that higher velocity of chilled air will improve heat transfer of the rack.
