The arbitrary Lagrangian-Eulerian(ALE) adaptive remeshing technology and the HyperXtrude software of transient finite element simulations were used on analogue simulation of aluminium extrusion processing.The field ...The arbitrary Lagrangian-Eulerian(ALE) adaptive remeshing technology and the HyperXtrude software of transient finite element simulations were used on analogue simulation of aluminium extrusion processing.The field distributions of strain rate,stress,temperature and velocity of metal flow were obtained.The results are basically consistent with the experiment,which indicates that this method may successfully predict the defects in the actual extrusion process.展开更多
Objectives:This study aimed to systematically evaluate the effects of constraint-induced aphasia therapy(OAT)for aphasic patients reported by randomized controlled trials.Methods:Relevant randomized controlled trials ...Objectives:This study aimed to systematically evaluate the effects of constraint-induced aphasia therapy(OAT)for aphasic patients reported by randomized controlled trials.Methods:Relevant randomized controlled trials were retrieved from 11 electronic databases.A methodological quality assessment was conducted in accordance with the Cochrane Handbook,and metaanalyses were performed by using RevMan 5.2.A descriptive analysis was conducted when the included trials were not suitable for a meta-analysis.Results:A total of 12 trials were included.A statistically significant group difference was shown from the meta-analysis in the results measured by the Western Aphasia Battery(random-effects model,MD=1.23,95%CI=0.31 to 2.14,P<0.01).However,there were no statistically significant differences shown in the results of the Boston Naming Test(fixed-effects model,MD=-1.79,95%CI=-11.19 to Z62,P>0.05)and Aachen Aphasia Test(fixed-effects model,MD=-1.11,95%CI=-4.49 to 2.27,P>0.05).The descriptive analysis showed positive results in language performances of naming,repetition,and comprehension.Conclusion:This systematic review indicated that CIAT was efficient for improving language performance with regard to naming,comprehension,repetition,written language,and oral language based on the current evidence.And this review provides some meaningful guides for clinical practice:expand the therapy duration to 2 or 3 h per day,focus on naming,and choose the best assessment tool.It also indicates a need for more rigorous,large-scale,and high-quality trials in the future.展开更多
Severe vibration of underground structures may be induced under blast loads. According to the characteristics of the explosion-induced ground shock wave, a new-type damper, inverse control magneto-rheological(MR) da...Severe vibration of underground structures may be induced under blast loads. According to the characteristics of the explosion-induced ground shock wave, a new-type damper, inverse control magneto-rheological(MR) damper was designed to control the vibration, The high-frequency performance test of the MR damper was carried out on the small shaking table. It is shown that the performance can be modeled by use of the modified Bouc-Wen model, and the Parameters of the model keep stable in the range of 15--50 Hz.展开更多
Based on the thermodynamics theory and physical micro-properties of solid materials subjected to external loading at room temperature,a formula of calculating temperature difference of infrared radiation in terms of t...Based on the thermodynamics theory and physical micro-properties of solid materials subjected to external loading at room temperature,a formula of calculating temperature difference of infrared radiation in terms of the sum of three principal strains was deduced to quantitatively investigate the infrared radiation characteristics in test. Two typical specimens,the three-point bending beam and the disc pressed in diameter,were tested and their principal strains were calculated by finite element method in order to obtain the temperature differences of infrared radiation. Numerical results are in a good agreement with test results,which verifies the validity of the formula of calculating temperature differences of infrared radiation and the model of quantitatively describing the infrared radiation characteristics of solid materials,and reveals the corresponding inner physical mechanism.展开更多
This paper reviews sulfur-induced passivity degradation of nuclear materials with emphasis on steam generator(SG)alloys. The state of arts on this topic concerning thermodynamic calculation and experimental data has b...This paper reviews sulfur-induced passivity degradation of nuclear materials with emphasis on steam generator(SG)alloys. The state of arts on this topic concerning thermodynamic calculation and experimental data has been reviewed. Thermodynamic calculation results indicate that the distribution of sulfur species strongly depends on p H and temperature. Experimental data show that solution p H, temperature and solution chemistries can significantly affect the electrochemical behaviors of SG materials and the underlying degradation mechanisms. Some issues when conducting corrosion tests at high temperature should be paid attention to, such as the dissolution of the autoclave, which may affect the facticity of the experimental results.展开更多
Gut and oral microflora are important factors in the pathogenesis and development of rheumatoid arthritis (RA). Recent studies have shown that probiotic supplements have beneficial consequences on experimental arthr...Gut and oral microflora are important factors in the pathogenesis and development of rheumatoid arthritis (RA). Recent studies have shown that probiotic supplements have beneficial consequences on experimental arthritis in rats. However, results from randomized clinical trials on the effects of probi- otics have not been consistent. The aim of this study was to systematically review the existing evidence for the effects of probiotic intervention in RA. We included randomized controlled trials (RCTs) of RA patients receiving stable treatment with disease-modifying anti-rheumatic drugs (DMARDs) that: ①were combined with additional probiotic supplements or ② were combined with either no additional supplements or only a placebo treatment. Statistical analysis was performed using Review Manager 5.3.3. Six randomized clinical trials were eligible for inclusion in the meta-analysis, with 249 participants in total. The results showed that the probiotic intervention treatment has not yet achieved significant improvement in the American College of Rheumatology 20% improvement criteria (ACR20) score and the disease activity score in 28 joints (DAS28). The laboratory index C-reactive protein (CRP) (mg.L-1) was significantly reduced in the intervention group. The expression of inflammatory cytokines tumor necrosis factor (TNF)-a and interleukine (IL)-ll] was also significantly reduced, while IL-10 expression increased in the probiotic intervention groups. This article is the first systematic review and meta-analysis providing a comprehensive assessment of the benefits of treating RA with probiotics. We found that probiotic supplementation may show a limited improvement in RA therapy in existing reports because of a lack of sufficiently high-quality work on the part of clinicians. More multi-centered, large-sample RCTs are needed in order to evaluate the benefits of probiotics in RA treatment.展开更多
Surgery following neoadjuvant chemoradiotherapy(NCRT) is a common multidisciplinary treatment for resectable esophageal cancer(EC). After analyzing 12 randomized controlled trials(RCTs), we discuss the key issues of s...Surgery following neoadjuvant chemoradiotherapy(NCRT) is a common multidisciplinary treatment for resectable esophageal cancer(EC). After analyzing 12 randomized controlled trials(RCTs), we discuss the key issues of surgery in the management of resectable EC. Along with chemoradiotherapy, NCRT is recommended for patients with squamous cell carcinoma(SCC) and adenocarcinoma(AC), and most chemotherapy regimens are based on cisplatin, fluorouracil(FU), or both(CF). However, taxane-based schedules or additional studies, together with newer chemotherapies, are warranted. In nine clinical trials, post-operative complications were similar without significant differences between two treatment groups. In-hospital mortality was significantly different in only 1 out of 10 trials. Half of the randomized trials that compare NCRT with surgery in EC demonstrate an increase in overall survival or disease-free survival. NCRT offers a great opportunity for margin negative resection, decreased disease stage, and improved loco-regional control. However, NCRT does not affect the quality of life when combined with esophagectomy. Future trials should focus on the identification of optimum regimens and selection of patients who are most likely to benefit from specific treatment options.展开更多
This paper aims to explore the construct validity of long dialogue multiple-choice (MC) listening comprehension tests through examining the retrospective verbal reports of eight Chinese EFL test-takers at tertiary lev...This paper aims to explore the construct validity of long dialogue multiple-choice (MC) listening comprehension tests through examining the retrospective verbal reports of eight Chinese EFL test-takers at tertiary level. It is found that the grammatical knowledge, discourse knowledge, pragmatic knowledge and sociolinguistic knowledge of language competence and all the cognitive and metacognitive strategies proposed in the framework of listening constructs are measured in the tests, which supports the constr...展开更多
Objective To provide an update on the evidence of the effectiveness of acupuncture in treating chronic non-specific low back pain(CNSLBP)based on randomized controlled trials(RCTs)of acupuncture for CNSLBP published b...Objective To provide an update on the evidence of the effectiveness of acupuncture in treating chronic non-specific low back pain(CNSLBP)based on randomized controlled trials(RCTs)of acupuncture for CNSLBP published between 2006 and 2020.Methods A comprehensive literature search was conducted through the University of Malta website,using the HyDi search engine.The‘Advanced Search’option was chosen in order to search for articles that were published in English,and associated with the key words,‘Chronic’,‘Acupuncture’,‘Needle’,‘Needling’,‘Non-specific’and‘Low Back Pain’,which were entered in their‘Subject’field,from the year 2006 till 2020.A comprehensive reading and analysis was done for the search result.Results Through the use of the HyDi search engine,accessible through the University of Malta,eighteen randomized controlled trials that met the criteria of this study were selected.Conclusion Through the analysis and comparison of the studies selected for this literature review,there is evidence providing that acupuncture is significantly more effective than current conservative treatment modalities for patients with CNSLBP in reducing pain and improving function.展开更多
Obesity has become a major health challenge for both patients and family physicians.Well-known methods of weight reduction such as diet and exercise are often difficult to comply with due to lifestyle and quality of l...Obesity has become a major health challenge for both patients and family physicians.Well-known methods of weight reduction such as diet and exercise are often difficult to comply with due to lifestyle and quality of life issues.Other methods such as diet pills or surgery have potentially serious side effects and often do not show long-term benefit.In an attempt to find a less invasive and effective modality of treatment,traditional Chinese medicine,particularly acupuncture and auriculotherapy,has become a topic of research in this field.The authors conducted a review of the current evidence regarding the use of auricular and body acupuncture in the treatment of obesity from their beginning to June 2014.Any published trial using randomized assignment to the intervention and control groups,in full text were included.Overall,moderate evidence in favor of acupuncture over exercise in the treatment of obesity was found.However,due to the limitations of the published studies in this field,it is necessary to conduct a large high quality randomized controlled trial in order to determine whether acupuncture should be used as a treatment modality to achieve weight loss in obese individuals.展开更多
基金Project (2009A080205003) supported by the Major Science and Technology Project of Guangdong Province,ChinaProject (30815009) supported by the Foundation of State Key Laboratory of Advanced Design and Manufacture for Vehicle Body,China
文摘The arbitrary Lagrangian-Eulerian(ALE) adaptive remeshing technology and the HyperXtrude software of transient finite element simulations were used on analogue simulation of aluminium extrusion processing.The field distributions of strain rate,stress,temperature and velocity of metal flow were obtained.The results are basically consistent with the experiment,which indicates that this method may successfully predict the defects in the actual extrusion process.
基金This study received no specific grant from any funding agency in the public,commercial,or not-for-profit sectors
文摘Objectives:This study aimed to systematically evaluate the effects of constraint-induced aphasia therapy(OAT)for aphasic patients reported by randomized controlled trials.Methods:Relevant randomized controlled trials were retrieved from 11 electronic databases.A methodological quality assessment was conducted in accordance with the Cochrane Handbook,and metaanalyses were performed by using RevMan 5.2.A descriptive analysis was conducted when the included trials were not suitable for a meta-analysis.Results:A total of 12 trials were included.A statistically significant group difference was shown from the meta-analysis in the results measured by the Western Aphasia Battery(random-effects model,MD=1.23,95%CI=0.31 to 2.14,P<0.01).However,there were no statistically significant differences shown in the results of the Boston Naming Test(fixed-effects model,MD=-1.79,95%CI=-11.19 to Z62,P>0.05)and Aachen Aphasia Test(fixed-effects model,MD=-1.11,95%CI=-4.49 to 2.27,P>0.05).The descriptive analysis showed positive results in language performances of naming,repetition,and comprehension.Conclusion:This systematic review indicated that CIAT was efficient for improving language performance with regard to naming,comprehension,repetition,written language,and oral language based on the current evidence.And this review provides some meaningful guides for clinical practice:expand the therapy duration to 2 or 3 h per day,focus on naming,and choose the best assessment tool.It also indicates a need for more rigorous,large-scale,and high-quality trials in the future.
基金Supported by National Nature Fund and National Civil-Defense Office
文摘Severe vibration of underground structures may be induced under blast loads. According to the characteristics of the explosion-induced ground shock wave, a new-type damper, inverse control magneto-rheological(MR) damper was designed to control the vibration, The high-frequency performance test of the MR damper was carried out on the small shaking table. It is shown that the performance can be modeled by use of the modified Bouc-Wen model, and the Parameters of the model keep stable in the range of 15--50 Hz.
基金Projects (10775018, 10702010, 50374073) supported by the National Natural Science Foundation of ChinaProject(2002CB412701) supported by the National Basic Research Program of China
文摘Based on the thermodynamics theory and physical micro-properties of solid materials subjected to external loading at room temperature,a formula of calculating temperature difference of infrared radiation in terms of the sum of three principal strains was deduced to quantitatively investigate the infrared radiation characteristics in test. Two typical specimens,the three-point bending beam and the disc pressed in diameter,were tested and their principal strains were calculated by finite element method in order to obtain the temperature differences of infrared radiation. Numerical results are in a good agreement with test results,which verifies the validity of the formula of calculating temperature differences of infrared radiation and the model of quantitatively describing the infrared radiation characteristics of solid materials,and reveals the corresponding inner physical mechanism.
基金Supported by the National Basic Research Program of China("973"Program,No.2014CB046805)National Natural Science Foundation of China(No.51131007,No.51371124)+1 种基金Natural Science Foundation of Tianjin(No.14JCYBJC17700)the Open-Ended Fund of the Key Laboratory of Nuclear Materials and Safety Assessment(Institute of Metal Research,Chinese Academy of Sciences,China)(No.2016NMSAKF02)
文摘This paper reviews sulfur-induced passivity degradation of nuclear materials with emphasis on steam generator(SG)alloys. The state of arts on this topic concerning thermodynamic calculation and experimental data has been reviewed. Thermodynamic calculation results indicate that the distribution of sulfur species strongly depends on p H and temperature. Experimental data show that solution p H, temperature and solution chemistries can significantly affect the electrochemical behaviors of SG materials and the underlying degradation mechanisms. Some issues when conducting corrosion tests at high temperature should be paid attention to, such as the dissolution of the autoclave, which may affect the facticity of the experimental results.
文摘Gut and oral microflora are important factors in the pathogenesis and development of rheumatoid arthritis (RA). Recent studies have shown that probiotic supplements have beneficial consequences on experimental arthritis in rats. However, results from randomized clinical trials on the effects of probi- otics have not been consistent. The aim of this study was to systematically review the existing evidence for the effects of probiotic intervention in RA. We included randomized controlled trials (RCTs) of RA patients receiving stable treatment with disease-modifying anti-rheumatic drugs (DMARDs) that: ①were combined with additional probiotic supplements or ② were combined with either no additional supplements or only a placebo treatment. Statistical analysis was performed using Review Manager 5.3.3. Six randomized clinical trials were eligible for inclusion in the meta-analysis, with 249 participants in total. The results showed that the probiotic intervention treatment has not yet achieved significant improvement in the American College of Rheumatology 20% improvement criteria (ACR20) score and the disease activity score in 28 joints (DAS28). The laboratory index C-reactive protein (CRP) (mg.L-1) was significantly reduced in the intervention group. The expression of inflammatory cytokines tumor necrosis factor (TNF)-a and interleukine (IL)-ll] was also significantly reduced, while IL-10 expression increased in the probiotic intervention groups. This article is the first systematic review and meta-analysis providing a comprehensive assessment of the benefits of treating RA with probiotics. We found that probiotic supplementation may show a limited improvement in RA therapy in existing reports because of a lack of sufficiently high-quality work on the part of clinicians. More multi-centered, large-sample RCTs are needed in order to evaluate the benefits of probiotics in RA treatment.
文摘Surgery following neoadjuvant chemoradiotherapy(NCRT) is a common multidisciplinary treatment for resectable esophageal cancer(EC). After analyzing 12 randomized controlled trials(RCTs), we discuss the key issues of surgery in the management of resectable EC. Along with chemoradiotherapy, NCRT is recommended for patients with squamous cell carcinoma(SCC) and adenocarcinoma(AC), and most chemotherapy regimens are based on cisplatin, fluorouracil(FU), or both(CF). However, taxane-based schedules or additional studies, together with newer chemotherapies, are warranted. In nine clinical trials, post-operative complications were similar without significant differences between two treatment groups. In-hospital mortality was significantly different in only 1 out of 10 trials. Half of the randomized trials that compare NCRT with surgery in EC demonstrate an increase in overall survival or disease-free survival. NCRT offers a great opportunity for margin negative resection, decreased disease stage, and improved loco-regional control. However, NCRT does not affect the quality of life when combined with esophagectomy. Future trials should focus on the identification of optimum regimens and selection of patients who are most likely to benefit from specific treatment options.
基金a small part of the research project"A Chronological Study of the CET Washback"(07BYY030)supported by the National Philosophy and Social Science Foundation of China . The teamleader is Gu Xiangdong.
文摘This paper aims to explore the construct validity of long dialogue multiple-choice (MC) listening comprehension tests through examining the retrospective verbal reports of eight Chinese EFL test-takers at tertiary level. It is found that the grammatical knowledge, discourse knowledge, pragmatic knowledge and sociolinguistic knowledge of language competence and all the cognitive and metacognitive strategies proposed in the framework of listening constructs are measured in the tests, which supports the constr...
基金国家中医药管理局中医药国际合作专项中医药国际化发展研究中心项目,No.GZYYGJ2020003University of Maltaand the Centre of Traditional Chinese Medicine and Culture,University of Malta.
文摘Objective To provide an update on the evidence of the effectiveness of acupuncture in treating chronic non-specific low back pain(CNSLBP)based on randomized controlled trials(RCTs)of acupuncture for CNSLBP published between 2006 and 2020.Methods A comprehensive literature search was conducted through the University of Malta website,using the HyDi search engine.The‘Advanced Search’option was chosen in order to search for articles that were published in English,and associated with the key words,‘Chronic’,‘Acupuncture’,‘Needle’,‘Needling’,‘Non-specific’and‘Low Back Pain’,which were entered in their‘Subject’field,from the year 2006 till 2020.A comprehensive reading and analysis was done for the search result.Results Through the use of the HyDi search engine,accessible through the University of Malta,eighteen randomized controlled trials that met the criteria of this study were selected.Conclusion Through the analysis and comparison of the studies selected for this literature review,there is evidence providing that acupuncture is significantly more effective than current conservative treatment modalities for patients with CNSLBP in reducing pain and improving function.
文摘Obesity has become a major health challenge for both patients and family physicians.Well-known methods of weight reduction such as diet and exercise are often difficult to comply with due to lifestyle and quality of life issues.Other methods such as diet pills or surgery have potentially serious side effects and often do not show long-term benefit.In an attempt to find a less invasive and effective modality of treatment,traditional Chinese medicine,particularly acupuncture and auriculotherapy,has become a topic of research in this field.The authors conducted a review of the current evidence regarding the use of auricular and body acupuncture in the treatment of obesity from their beginning to June 2014.Any published trial using randomized assignment to the intervention and control groups,in full text were included.Overall,moderate evidence in favor of acupuncture over exercise in the treatment of obesity was found.However,due to the limitations of the published studies in this field,it is necessary to conduct a large high quality randomized controlled trial in order to determine whether acupuncture should be used as a treatment modality to achieve weight loss in obese individuals.