AIM: To study the clinicopathological characteristics of unsuspected gallbladder carcinoma (UGC). METHODS: We retrospectively studied 23 cases of UGC in Tongji Hospital, and compared their clinicopathological char...AIM: To study the clinicopathological characteristics of unsuspected gallbladder carcinoma (UGC). METHODS: We retrospectively studied 23 cases of UGC in Tongji Hospital, and compared their clinicopathological characteristics with 33 cases of preoperatively diagnosed gallbladder carcinoma (PDGC). RESULTS: The proportion of UGC coexisting with cholecystolithiasis was significantly higher than that of PDGC (x^2 = 13.53, P 〈 0.01). The infection rate of hepatitis B virus was 21.74% (5/23) in UGC and 30.30% (10/33) in PDGC. Nine (39.13%) of 23 patients with UGC and 8/33 (24.24) PDGC had contact with schistosome pestilent water. The rate of multiple pregnancies was 56.52% (13/23) in the patients with UGC and 42.42% (14/33) in PDGC. The primary location of the UGC was mostly in the neck and body of the gallbladder, and that of the PDGC was often in the body and bottom. The incidence of Nevin stage I and 11 UGC was significantly higher than that of PDGC (x^2 = 4.44, P 〈 0.05 and 2 = 4.96, P 〈 0.05) while that of Nevin stage V UGC was significantly lower than that of PDGC (x^2 = 7.59, P 〈 0.01). According to the grading of carcinoma, the incidence of well-differentiated UGC was significantly higher than that of PDGC (2 = 4.16, P 〈 0.05), and that of poorlydifferentiated UGC was significantly lower than that of PDGC (x^2 = 4.48, P 〈 0.05).CONCLUSION: There are different characteristics between UGC and PDGC, such as in primary location, malignant degree and incidence of coexistence with cholecystolithiasis. Cholecystolithiasis, hepatitis B, schistosome and multiple pregnancies were high risk factors for gallbladder carcinoma.展开更多
Aortoesophageal fistula(AEF)is a rare and fatal disorder. It is also a life-threatening cause of massive upper gastrointestinal hemorrhage.Thoracic aortic aneurysm is the most common cause of AEF.Management of a patie...Aortoesophageal fistula(AEF)is a rare and fatal disorder. It is also a life-threatening cause of massive upper gastrointestinal hemorrhage.Thoracic aortic aneurysm is the most common cause of AEF.Management of a patient with this disorder requires rapid diagnosis and immediate intervention,which is considered the best way to save the patient's life.We report a case of AEF misdiagnosed as esophageal polyp.展开更多
文摘AIM: To study the clinicopathological characteristics of unsuspected gallbladder carcinoma (UGC). METHODS: We retrospectively studied 23 cases of UGC in Tongji Hospital, and compared their clinicopathological characteristics with 33 cases of preoperatively diagnosed gallbladder carcinoma (PDGC). RESULTS: The proportion of UGC coexisting with cholecystolithiasis was significantly higher than that of PDGC (x^2 = 13.53, P 〈 0.01). The infection rate of hepatitis B virus was 21.74% (5/23) in UGC and 30.30% (10/33) in PDGC. Nine (39.13%) of 23 patients with UGC and 8/33 (24.24) PDGC had contact with schistosome pestilent water. The rate of multiple pregnancies was 56.52% (13/23) in the patients with UGC and 42.42% (14/33) in PDGC. The primary location of the UGC was mostly in the neck and body of the gallbladder, and that of the PDGC was often in the body and bottom. The incidence of Nevin stage I and 11 UGC was significantly higher than that of PDGC (x^2 = 4.44, P 〈 0.05 and 2 = 4.96, P 〈 0.05) while that of Nevin stage V UGC was significantly lower than that of PDGC (x^2 = 7.59, P 〈 0.01). According to the grading of carcinoma, the incidence of well-differentiated UGC was significantly higher than that of PDGC (2 = 4.16, P 〈 0.05), and that of poorlydifferentiated UGC was significantly lower than that of PDGC (x^2 = 4.48, P 〈 0.05).CONCLUSION: There are different characteristics between UGC and PDGC, such as in primary location, malignant degree and incidence of coexistence with cholecystolithiasis. Cholecystolithiasis, hepatitis B, schistosome and multiple pregnancies were high risk factors for gallbladder carcinoma.
文摘Aortoesophageal fistula(AEF)is a rare and fatal disorder. It is also a life-threatening cause of massive upper gastrointestinal hemorrhage.Thoracic aortic aneurysm is the most common cause of AEF.Management of a patient with this disorder requires rapid diagnosis and immediate intervention,which is considered the best way to save the patient's life.We report a case of AEF misdiagnosed as esophageal polyp.