Recent advances in effective antimicrobial prophylactic strategies have led to a decline in the incidence of opportunistic infections in liver transplant recipients. However, morbidity and mortality due to infectious ...Recent advances in effective antimicrobial prophylactic strategies have led to a decline in the incidence of opportunistic infections in liver transplant recipients. However, morbidity and mortality due to infectious diseases remain as major problems. Bacterial infections occurring early after transplant are mainly related to the technical aspects of the procedure. By contrast, after the first postoperative days and beyond, the nature and variety of infectious complications change. Opportunistic bacterial infections are uncommon after 6 mo in patients receiving stable and reduced maintenance doses of immunosuppression with good graft function and little is documented about these cases in the literature. Transplant recipients may be more susceptible to some pathogens, such as the Nocardia species, Legionella species, Listeria monocytogenes , Mycoplasma species, Salmonella species or Rhodococcus equi. Respiratory infections due to capsulated bacteria, such as Streptococcus pneumoniae and Haemophilus intTuenza, can be life- threatening if not promptly treated in this population. These late bacterial infections may be very difficult to recognize and treat in this population. In this article, we review what has been described in the literature with regards to late bacterial infections following liver transplantation.展开更多
Separation process undertaken in packed columns often displays anisotropic turbulent mass diffusion. The anisotropic turbulent mass diffusion can be characterized rigorously by using the Reynolds mass flux(RMF) model....Separation process undertaken in packed columns often displays anisotropic turbulent mass diffusion. The anisotropic turbulent mass diffusion can be characterized rigorously by using the Reynolds mass flux(RMF) model.With the RMF model, the concentration and temperature as well as the velocity distributions can be simulated numerically. The modeled Reynolds mass flux equation is adopted to close the turbulent mass transfer equation,while the modeled Reynolds heat flux and Reynolds stress equations are used to close the turbulent heat and momentum transfer equations, so that the Boussinesq postulate and the isotropic assumption are abandoned. To validate the presented RMF model, simulation is carried out for CO2 absorption into aqueous Na OH solutions in a packed column(0.1 m id, packed with 12.7 mm Berl saddles up to a height of 6.55 m). The simulated results are compared with the experimental data and satisfactory agreement is found both in concentration and temperature distributions. The sequel Part II extends the model application to the simulation of an unsteady state adsorption process in a packed column.展开更多
In their attempt to construct their identity in opposition to European one, non-Western new nations with alphabets such as Greek, Hebrew, or Cyrillic, used them as a way of emphasizing difference, and thus provide sym...In their attempt to construct their identity in opposition to European one, non-Western new nations with alphabets such as Greek, Hebrew, or Cyrillic, used them as a way of emphasizing difference, and thus provide symbolic spaces for the newborn nations. The illegibility of these alphabets for Western people, along with the ancient prestige of at least Hebrew and Greek, fostered the illusion of temporal continuity and provided legitimacy to their atomization projects. Odysseas Elytis （1911-1996）, Nobel Prize for Literature winner in 1979 and the last national poet of Greece, blends this old tendency in Greek culture and the broader claim of modern European poets for the essential autonomy of art and literature. His efforts to reinforce the walls separating Greece from Latin-Western culture by reinforcing the illegibility of both Greek and poetic idioms, aim at constructing a more essential Greece, founded on aesthetics, language, and writing instead of politics, institutions, or geographic borders. In this paper engaging mainly in the fields of literary and postcolonial studies, the author intends to analyze the mechanisms by which language, writing, or literature can be used to （re）cipher once again the already exclusive concept of nation, and thus to undermine every possibility of deciphering and translatability. He concludes that in “conceptually colonized” nations such as Greece, this process implies and anticolonial movement still caught nevertheless in a colonial discursivity.展开更多
Numerical results of three-dimensional separated flow and heat transfer in an enlarged rectangular channel are presented in this paper.The expansion ratio and aspect ratio of the channel are 2.0 and 16.0,respectively....Numerical results of three-dimensional separated flow and heat transfer in an enlarged rectangular channel are presented in this paper.The expansion ratio and aspect ratio of the channel are 2.0 and 16.0,respectively.Reynolds number of the flow is 200 and it is over the critical Reynolds number.Over the critical Reynolds number,the flow in the symmetric channel becomes asymmetric and deflects to one side of the walls.Effects of the pulsating fluctuation at the inlet upon the flow in the channel are investigated.It is clarified that the inlet flow with a pulsating fluctuation of Strouhal number 0.05 and 0.10 strongly affects on the flow in the channel,and heat transfer on the walls is enhanced,especially on the wall surface covered with long separation bubble.On the other hand,the pulsation of St=0.0125 oscillates the shear layer more weakly than that of St=0.05,0.10 and the enhancement of heat transfer is smaller,though some vortices are shed from the vicinity of the side wall near the reattachment region.The oscillation of the main flow calms down gradually as the Strouhal number of the pulsation increases over 0.10.The influence of pulsation of St=0.20 on the flow is restricted in the near downstream of the step,and heat transfer on the walls is almost similar to that of the steady flow in the channel.展开更多
Microfluidic droplets have emerged as novel platforms for chemical and biological applications. Manipulation of droplets has thus attracted increasing attention. Different from solid particles, deformable droplets can...Microfluidic droplets have emerged as novel platforms for chemical and biological applications. Manipulation of droplets has thus attracted increasing attention. Different from solid particles, deformable droplets cannot be efficiently controlled by inertia-driven approaches. Here, we report a study on the lateral migration of dual droplet trains in a double spiral microchannel at low Reynolds numbers. The dominant driving mechanism is elucidated as wall effect originated from the droplet deformation. Three types of migration modes are observed with varying Reynolds numbers and the size-dependent mode is intensively investigated. We obtain empirical formulas by relating the migration to Reynolds numbers and droplet sizes. The effect of droplet deformability on the migration and the detailed migration behavior along the double spiral channel are discussed. Numerical simulations are also performed and yielded in qualitative agreement with the experiments. could be a promising alternative to existing inertia-driven approaches bio-particles. This proposed low Re approach based on lateral migration especially concerning deformable entities and susceptible展开更多
Peristaltic flow of magnetohydrodynamic （MHD） Williamson fluid in a symmetric chan- nel is addressed. Modeling is given with Sorer and Dufour effects. Channel walls have compliant properties. Analysis has been carri...Peristaltic flow of magnetohydrodynamic （MHD） Williamson fluid in a symmetric chan- nel is addressed. Modeling is given with Sorer and Dufour effects. Channel walls have compliant properties. Analysis has been carried out through long wavelength and low Reynolds number approach. The obtained series solutions for small Weissenberg number are developed. Impact of variables reflecting the salient features of wall properties, Blot numbers and Soret and Dufour on the velocity, temperature and concentration has been point out. Trapping phenomenon is also analyzed.展开更多
A challenge in the study of turbulent boundary layers(TBLs) is to understand the non-equilibrium relaxation process after separation and reattachment due to shock-wave/boundary-layer interaction. The classical boundar...A challenge in the study of turbulent boundary layers(TBLs) is to understand the non-equilibrium relaxation process after separation and reattachment due to shock-wave/boundary-layer interaction. The classical boundary layer theory cannot deal with the strong adverse pressure gradient, and hence, the computational modeling of this process remains inaccurate. Here, we report the direct numerical simulation results of the relaxation TBL behind a compression ramp, which reveal the presence of intense large-scale eddies, with significantly enhanced Reynolds stress and turbulent heat flux. A crucial finding is that the wall-normal profiles of the excess Reynolds stress and turbulent heat flux obey a β-distribution, which is a product of two power laws with respect to the wall-normal distances from the wall and from the boundary layer edge. In addition, the streamwise decays of the excess Reynolds stress and turbulent heat flux also exhibit power laws with respect to the streamwise distance from the corner of the compression ramp. These results suggest that the relaxation TBL obeys the dilation symmetry, which is a specific form of self-organization in this complex non-equilibrium flow. The β-distribution yields important hints for the development of a turbulence model.展开更多
The work deals with numerical modelling of turbulent flows in channels with an expansion of the cross-section where flow separation and reattachment occur. The performance of several eddy viscosity models and an expli...The work deals with numerical modelling of turbulent flows in channels with an expansion of the cross-section where flow separation and reattachment occur. The performance of several eddy viscosity models and an explicit algebraic Reynolds stress model (EARSM) is studied. The used test cases are flows in channels with various backward facing steps where the step is perpendicular or inclined and the top wall is parallel or deflected. Furthermore, a channel with the circular ramp is considered. The numerical solution is achieved by the finite volume method or by the finite element method. The results of both numerical approaches are compared.展开更多
文摘Recent advances in effective antimicrobial prophylactic strategies have led to a decline in the incidence of opportunistic infections in liver transplant recipients. However, morbidity and mortality due to infectious diseases remain as major problems. Bacterial infections occurring early after transplant are mainly related to the technical aspects of the procedure. By contrast, after the first postoperative days and beyond, the nature and variety of infectious complications change. Opportunistic bacterial infections are uncommon after 6 mo in patients receiving stable and reduced maintenance doses of immunosuppression with good graft function and little is documented about these cases in the literature. Transplant recipients may be more susceptible to some pathogens, such as the Nocardia species, Legionella species, Listeria monocytogenes , Mycoplasma species, Salmonella species or Rhodococcus equi. Respiratory infections due to capsulated bacteria, such as Streptococcus pneumoniae and Haemophilus intTuenza, can be life- threatening if not promptly treated in this population. These late bacterial infections may be very difficult to recognize and treat in this population. In this article, we review what has been described in the literature with regards to late bacterial infections following liver transplantation.
基金Supported by the National Natural Science Foundation of China(21376163)
文摘Separation process undertaken in packed columns often displays anisotropic turbulent mass diffusion. The anisotropic turbulent mass diffusion can be characterized rigorously by using the Reynolds mass flux(RMF) model.With the RMF model, the concentration and temperature as well as the velocity distributions can be simulated numerically. The modeled Reynolds mass flux equation is adopted to close the turbulent mass transfer equation,while the modeled Reynolds heat flux and Reynolds stress equations are used to close the turbulent heat and momentum transfer equations, so that the Boussinesq postulate and the isotropic assumption are abandoned. To validate the presented RMF model, simulation is carried out for CO2 absorption into aqueous Na OH solutions in a packed column(0.1 m id, packed with 12.7 mm Berl saddles up to a height of 6.55 m). The simulated results are compared with the experimental data and satisfactory agreement is found both in concentration and temperature distributions. The sequel Part II extends the model application to the simulation of an unsteady state adsorption process in a packed column.
文摘In their attempt to construct their identity in opposition to European one, non-Western new nations with alphabets such as Greek, Hebrew, or Cyrillic, used them as a way of emphasizing difference, and thus provide symbolic spaces for the newborn nations. The illegibility of these alphabets for Western people, along with the ancient prestige of at least Hebrew and Greek, fostered the illusion of temporal continuity and provided legitimacy to their atomization projects. Odysseas Elytis （1911-1996）, Nobel Prize for Literature winner in 1979 and the last national poet of Greece, blends this old tendency in Greek culture and the broader claim of modern European poets for the essential autonomy of art and literature. His efforts to reinforce the walls separating Greece from Latin-Western culture by reinforcing the illegibility of both Greek and poetic idioms, aim at constructing a more essential Greece, founded on aesthetics, language, and writing instead of politics, institutions, or geographic borders. In this paper engaging mainly in the fields of literary and postcolonial studies, the author intends to analyze the mechanisms by which language, writing, or literature can be used to （re）cipher once again the already exclusive concept of nation, and thus to undermine every possibility of deciphering and translatability. He concludes that in “conceptually colonized” nations such as Greece, this process implies and anticolonial movement still caught nevertheless in a colonial discursivity.
基金These results were partly obtained with a supercomputer SX-9 of Cyberscience Center,Tohoku University
文摘Numerical results of three-dimensional separated flow and heat transfer in an enlarged rectangular channel are presented in this paper.The expansion ratio and aspect ratio of the channel are 2.0 and 16.0,respectively.Reynolds number of the flow is 200 and it is over the critical Reynolds number.Over the critical Reynolds number,the flow in the symmetric channel becomes asymmetric and deflects to one side of the walls.Effects of the pulsating fluctuation at the inlet upon the flow in the channel are investigated.It is clarified that the inlet flow with a pulsating fluctuation of Strouhal number 0.05 and 0.10 strongly affects on the flow in the channel,and heat transfer on the walls is enhanced,especially on the wall surface covered with long separation bubble.On the other hand,the pulsation of St=0.0125 oscillates the shear layer more weakly than that of St=0.05,0.10 and the enhancement of heat transfer is smaller,though some vortices are shed from the vicinity of the side wall near the reattachment region.The oscillation of the main flow calms down gradually as the Strouhal number of the pulsation increases over 0.10.The influence of pulsation of St=0.20 on the flow is restricted in the near downstream of the step,and heat transfer on the walls is almost similar to that of the steady flow in the channel.
基金supported by the National Natural Science Foundation of China(Grant Nos.11572334,11272321 and 11402274)
文摘Microfluidic droplets have emerged as novel platforms for chemical and biological applications. Manipulation of droplets has thus attracted increasing attention. Different from solid particles, deformable droplets cannot be efficiently controlled by inertia-driven approaches. Here, we report a study on the lateral migration of dual droplet trains in a double spiral microchannel at low Reynolds numbers. The dominant driving mechanism is elucidated as wall effect originated from the droplet deformation. Three types of migration modes are observed with varying Reynolds numbers and the size-dependent mode is intensively investigated. We obtain empirical formulas by relating the migration to Reynolds numbers and droplet sizes. The effect of droplet deformability on the migration and the detailed migration behavior along the double spiral channel are discussed. Numerical simulations are also performed and yielded in qualitative agreement with the experiments. could be a promising alternative to existing inertia-driven approaches bio-particles. This proposed low Re approach based on lateral migration especially concerning deformable entities and susceptible
文摘Peristaltic flow of magnetohydrodynamic （MHD） Williamson fluid in a symmetric chan- nel is addressed. Modeling is given with Sorer and Dufour effects. Channel walls have compliant properties. Analysis has been carried out through long wavelength and low Reynolds number approach. The obtained series solutions for small Weissenberg number are developed. Impact of variables reflecting the salient features of wall properties, Blot numbers and Soret and Dufour on the velocity, temperature and concentration has been point out. Trapping phenomenon is also analyzed.
基金supported by the National Natural Science Foundation of China (Grant Nos. 11452002, 11372008, and 11521091)the Aeronautical Science Foundation of China (Grant No. 2014ZA71001)
文摘A challenge in the study of turbulent boundary layers(TBLs) is to understand the non-equilibrium relaxation process after separation and reattachment due to shock-wave/boundary-layer interaction. The classical boundary layer theory cannot deal with the strong adverse pressure gradient, and hence, the computational modeling of this process remains inaccurate. Here, we report the direct numerical simulation results of the relaxation TBL behind a compression ramp, which reveal the presence of intense large-scale eddies, with significantly enhanced Reynolds stress and turbulent heat flux. A crucial finding is that the wall-normal profiles of the excess Reynolds stress and turbulent heat flux obey a β-distribution, which is a product of two power laws with respect to the wall-normal distances from the wall and from the boundary layer edge. In addition, the streamwise decays of the excess Reynolds stress and turbulent heat flux also exhibit power laws with respect to the streamwise distance from the corner of the compression ramp. These results suggest that the relaxation TBL obeys the dilation symmetry, which is a specific form of self-organization in this complex non-equilibrium flow. The β-distribution yields important hints for the development of a turbulence model.
基金supported by Grant Number 103/09/0977 of Czech Science FoundationResearch Plans of MSMT No. 6840770010 and No. AV0Z207 60514
文摘The work deals with numerical modelling of turbulent flows in channels with an expansion of the cross-section where flow separation and reattachment occur. The performance of several eddy viscosity models and an explicit algebraic Reynolds stress model (EARSM) is studied. The used test cases are flows in channels with various backward facing steps where the step is perpendicular or inclined and the top wall is parallel or deflected. Furthermore, a channel with the circular ramp is considered. The numerical solution is achieved by the finite volume method or by the finite element method. The results of both numerical approaches are compared.
