针对某型车辆柴油发电机设计了基于TMS320F28335芯片的数字电压调节器,考虑到数字电压调节器的特点与功能,对其输入输出接口电路展开设计,包括模拟量调理电路、数字量调理电路、励磁主电路和励磁驱动电路等。充分利用以TMS320F28335为...针对某型车辆柴油发电机设计了基于TMS320F28335芯片的数字电压调节器,考虑到数字电压调节器的特点与功能,对其输入输出接口电路展开设计,包括模拟量调理电路、数字量调理电路、励磁主电路和励磁驱动电路等。充分利用以TMS320F28335为主的数字信号处理器(Digital Signal Processor,DSP)最小系统,将其作为主要控制器,在符合比例-积分-微分控制(Proportion-Integral-Differential,PID)算法的要求下,设置了系统实验平台,以供参考。展开更多
H3K9me2 and H3K27me2 are important epigenetic marks associated with transcription repression, while H3K4me3 is associated with transcription activation. It has been shown that active and repressive histone methylation...H3K9me2 and H3K27me2 are important epigenetic marks associated with transcription repression, while H3K4me3 is associated with transcription activation. It has been shown that active and repressive histone methylations distribute in a mutually exclusive manner, but the underlying mechanism was poorly understood. Here we identified ceKDM7A, a PHD (plant homeodomain)- and JmjC domain-containing protein, as a histone demethylase specific for H3K9me2 and H3K27me2. We further demonstrated that the PHD domain of ceKDM7A bound H3K4me3 and H3K4me3 co-localized with ceKDM7A at the genome-wide level. Disruption of the PHD domain binding to H3K4me3 reduced the demethylase activity in vivo, and loss of ceKDM7A reduced the expression of its associated target genes. These results indicate that ceKDM7A is recruited to the promoter to demethylate H3K9me2 and H3K27me2 and activate gene expression through the binding of the PHD domain to H3K4me3. Thus, our study identifies a dual-specificity histone demethylase and provides novel insights into the regulation of histone methylation.展开更多
We have combined two planar nanostructures, graphene and CdSe nanobelts, to construct Schottky junction solar cells with open-circuit voltages of about 0.5 V and cell efficiencies on the order of 0.1%. By covering tra...We have combined two planar nanostructures, graphene and CdSe nanobelts, to construct Schottky junction solar cells with open-circuit voltages of about 0.5 V and cell efficiencies on the order of 0.1%. By covering transparent graphene or carbon nanotube (CNT) films on selected positions along macroscopically long CdSe nanobelts, we have demonstrated the fabrication of active solar cells with many different configurations and parallel connections from individual or multiple assembled nanobelts. The graphene-CdSe nanobelt solar cells reported here show a great flexibility in creating diverse device architectures, and might be scaled up for cell integration based on assembled nanobelt arrays and patterned graphene (or CNT) films.展开更多
文摘针对某型车辆柴油发电机设计了基于TMS320F28335芯片的数字电压调节器,考虑到数字电压调节器的特点与功能,对其输入输出接口电路展开设计,包括模拟量调理电路、数字量调理电路、励磁主电路和励磁驱动电路等。充分利用以TMS320F28335为主的数字信号处理器(Digital Signal Processor,DSP)最小系统,将其作为主要控制器,在符合比例-积分-微分控制(Proportion-Integral-Differential,PID)算法的要求下,设置了系统实验平台,以供参考。
文摘H3K9me2 and H3K27me2 are important epigenetic marks associated with transcription repression, while H3K4me3 is associated with transcription activation. It has been shown that active and repressive histone methylations distribute in a mutually exclusive manner, but the underlying mechanism was poorly understood. Here we identified ceKDM7A, a PHD (plant homeodomain)- and JmjC domain-containing protein, as a histone demethylase specific for H3K9me2 and H3K27me2. We further demonstrated that the PHD domain of ceKDM7A bound H3K4me3 and H3K4me3 co-localized with ceKDM7A at the genome-wide level. Disruption of the PHD domain binding to H3K4me3 reduced the demethylase activity in vivo, and loss of ceKDM7A reduced the expression of its associated target genes. These results indicate that ceKDM7A is recruited to the promoter to demethylate H3K9me2 and H3K27me2 and activate gene expression through the binding of the PHD domain to H3K4me3. Thus, our study identifies a dual-specificity histone demethylase and provides novel insights into the regulation of histone methylation.
基金This work was supported by the National Science Foundation of China (NSFC) under grant number 51072005. H. W. Zhu acknowledges the support by theNational Science Foundation of China (No. 50972067), Tsinghua National Laboratory for Information Science and Technology (TNList) Cross-discipline Foundation and Foundation for the Authors of National Excellent Doctoral Dissertations (No. 201038). We acknowledge Yan Li from College of Chemistry in Peking University for help in Raman measurement.
文摘We have combined two planar nanostructures, graphene and CdSe nanobelts, to construct Schottky junction solar cells with open-circuit voltages of about 0.5 V and cell efficiencies on the order of 0.1%. By covering transparent graphene or carbon nanotube (CNT) films on selected positions along macroscopically long CdSe nanobelts, we have demonstrated the fabrication of active solar cells with many different configurations and parallel connections from individual or multiple assembled nanobelts. The graphene-CdSe nanobelt solar cells reported here show a great flexibility in creating diverse device architectures, and might be scaled up for cell integration based on assembled nanobelt arrays and patterned graphene (or CNT) films.