Crystalline@amorphous NiCo_(2)S_(4)@MoS_(2)(v-NCS@MS)nanostructures were designed and constructed via an ethylene glycol-induced strategy with hydrothermal synthesis and solvothermal method,which simultaneously realiz...Crystalline@amorphous NiCo_(2)S_(4)@MoS_(2)(v-NCS@MS)nanostructures were designed and constructed via an ethylene glycol-induced strategy with hydrothermal synthesis and solvothermal method,which simultaneously realized the defect regulation of crystal NiCo_(2)S_(4) in the core.Taking advantage of the flexible protection of an amor-phous shell and the high capacity of a conductive core with defects,the v-NCS@MS electrode exhibited high specif-ic capacity(1034 mAh·g^(-1) at 1 A·g^(-1))and outstanding rate capability.Moreover,a hybrid supercapacitor was assembled with v-NCS@MS as cathode and activated carbon(AC)as anode,which can achieve remarkably high specific energy of 111 Wh·kg^(-1) at a specific power of 219 W·kg^(-1) and outstanding capacity retention of 80.5%after 15000 cycling at different current densities.展开更多
A new FM transmitter is reported. It adopts a fractional-N PLL synthesizer to realize the FM modulator. An extra offset current has also been applied to eliminate the effects of the mismatch in CP. The chip is fabrica...A new FM transmitter is reported. It adopts a fractional-N PLL synthesizer to realize the FM modulator. An extra offset current has also been applied to eliminate the effects of the mismatch in CP. The chip is fabricated with CSMC 0.5μm DPTM CMOS technology. Experiments show that it achieves THD≤0.08% and SNR≤ 82dB,and the maximum outband emission energy ≤ 90dBc/Hz. Furthermore,it also uses an auto frequency adjusting method to avoid tuning up the external inductances. All these merits are very suitable for FM transmission.展开更多
The oil film clutch, which is superior in speed adjustment, is capable of being used in the belt conveyor to carry out soft start operation. According to running properties of both belt conveyor and oil film clutch...The oil film clutch, which is superior in speed adjustment, is capable of being used in the belt conveyor to carry out soft start operation. According to running properties of both belt conveyor and oil film clutch, equations that are used to decide the lubricating oil flow and the number of oil films (i.e. the number of rotating and stationary plates) are deduced theoretically. Also key parameters are provided for the design of the hydraulic system. All these together provide the theoretical basis for the soft start design of the belt conveyor and references for the application of the oil film clutch in similar fields.展开更多
Two different poling techniques-corona poling and contact poling in the backdrop of electro-optic (EO) polymer modulators are compared. A 3-layer structure EO polymer modulator is prepared for the poling. The poling...Two different poling techniques-corona poling and contact poling in the backdrop of electro-optic (EO) polymer modulators are compared. A 3-layer structure EO polymer modulator is prepared for the poling. The poling setups and procedures of these two different methods are given. It is found that a well-controlled precure step is very critical, otherwise it will result in either lower poling efficiency or damaged film. Experimental results show that contact poling does not create severe surface damage as corona poling and poling voltage is much lower, but corona poling provides higher EO effect than contact poling. Besides, contact poling can provide poling size as large as the substrate size.展开更多
A Mach-Zehnder(MZ) electro-optic(EO) modulator are real iz ed,with three optical layers as polymer materials.The functional layer is the co rona poled crosslinkable polyurethane.The ridge waveguide is fabricated by us...A Mach-Zehnder(MZ) electro-optic(EO) modulator are real iz ed,with three optical layers as polymer materials.The functional layer is the co rona poled crosslinkable polyurethane.The ridge waveguide is fabricated by using the spin-coating,poling,photolithography and oxygen reactive ion etching(RIE) techniques.The mode and the modulation properties of these devices are demonstra ted in a micron control system,while the light source works at the wavelength of 1 31 or 1 55 micron.展开更多
A new coarse tuning loop for a wide-band dual-loop frequency synthesizer is presented. The coarse tuning structure is composed of two digital modules, including a successive approximation register and a frequency comp...A new coarse tuning loop for a wide-band dual-loop frequency synthesizer is presented. The coarse tuning structure is composed of two digital modules, including a successive approximation register and a frequency comparator with a novel structure. The frequency comparator counts the prescaler cycles within a certain reference time and compares the number with preset data to estimate the VCO frequency. The frequency comparison error is analyzed in detail. Within a given coarse tuning time,our proposed structure shows a comparison error 20 times smaller than that of other reported structures. This structure also reuses the programmable divider as a part of the coarse tuning loop so that the circuit is greatly simplified.展开更多
The nonlinear coupled-mode equations are rewritten by even and odd modes.We study modulation instability(MI) of dispersion-shifted fiber couplers when either even or odd mode is launched alone by using zero-dispersion...The nonlinear coupled-mode equations are rewritten by even and odd modes.We study modulation instability(MI) of dispersion-shifted fiber couplers when either even or odd mode is launched alone by using zero-dispersion wavelength relatively long(quasi-cw) pulses.The result shows that there are new types of MI in both the normal-dispersion and the anomalous-dispersion regimes.MI is concerned with forth-order dispersion and has no relation with third-order dispersion.Quasi-cw can be changed into pulses array under certain conditions.We can extract super short pulse from this.Furthermore,the bandwidth of gain spectra widens and its strength accretes as the input power increases.展开更多
Several drugs are used in the treatment of irritable bowel syndrome (IBS) but all have side effects and variable efficacy. Considering the role of the gut-brain axis, immune, neural, and endocrine pathways in the pa...Several drugs are used in the treatment of irritable bowel syndrome (IBS) but all have side effects and variable efficacy. Considering the role of the gut-brain axis, immune, neural, and endocrine pathways in the patho- genesis of IBS and possible beneficial effects of benzodiazepines (BZD) in this axis, the present systematic review focuses on the efficacy of BZD receptor modulators in human IBS. For the years 1966 to February 2011, all literature was searched for any articles on the use of BZD receptor modulators and IBS. After thorough evaluation and omission of duplicate data, 10 out of 69 articles were included. BZD receptor modulators can be helpful, especially in the diarrhea-dominant form of IBS, by affecting the inflammatory, neural, and psychologic pathways, however, controversies still exist. Recently, a new BZD receptor modulator, dextofisoparn was synthesized and studied in human subjects, but the studies are limited to phase 11 b clinical trials. None of the existing trials considered the neuroimmunomodulatory effect of BZDs in IBS, but bearing in mind the concentration- dependent effect of BZDs on cytokines and cell proliferation, future studies using pharmacodynamic and pharmacokinetic approaches are highly recommended.展开更多
Cloud radiative effects (CREs) at the top of the atmosphere (TOA) in three reanalysis datasets (the Eur- opean Center for Medium-Range Weather Forecasts In- terim Reanalysis (ERA-Interim), the Japanese 55-yr Re...Cloud radiative effects (CREs) at the top of the atmosphere (TOA) in three reanalysis datasets (the Eur- opean Center for Medium-Range Weather Forecasts In- terim Reanalysis (ERA-Interim), the Japanese 55-yr Re- analysis Project (JRA-55), and the Modem-Era Retro- spective Analysis for Research and Applications (MERRA)) are evaluated using recent satellite-based observations. The reanalyses can basically capture the spatial pattern of the annual mean shortwave CRE, but the global mean longwave CRE in ERA-interim and JRA55 is weaker than observed, leading to overestimations of the net CRE. Moreover, distinct CRE biases of the reanalyses occur in the Intertropical Convergence Zone (ITCZ), coastal Pa- cific and Atlantic regions, and East Asia. Quantitative examination further indicates that the spatial correlations of CREs and TOA upward radiation fluxes with corre- sponding observations in ERA-Interim are better than in the other two reanalyses. Although MERRA has certain abilities in producing the magnitudes of global mean CREs, its performance in terms of spatial correlations in winter and summer are worse than for the other two re- analyses. The ability of JRA55 in reflecting CREs lies between the other two datasets. Compared to the global mean results, the spatial correlations of shortwave CRE in East Asia decrease and the biases of regional mean CREs increase in the three reanalyses. This implies that, cur- rently, it is still difficult to reproduce East Asian CREs based on these reanalyses. Relatively, ERA-Interim de- scribes the seasonal variation of East Asian CREs well, albeit weaker than observed. The present study also sug- gests that in-depth exploration of the ability of reanalysis data to describe aspects relating to cloud properties and rad- iation is needed usin~ more comprehensive observations.展开更多
This paper presents the design considerations and implementation of a novel topology digital multistage-noise-shaping (MASH) delta-sigma modulator suitable for fractional-N phase-locked-loop (PLL) frequency synthe...This paper presents the design considerations and implementation of a novel topology digital multistage-noise-shaping (MASH) delta-sigma modulator suitable for fractional-N phase-locked-loop (PLL) frequency synthesis. In an effort to reduce the complexity and dissipation,a pipeline technique has been used, and the proposed carry save tree (CST) algorithm optimizes the multi-input adder structure. The circuit has been verified through Matlab simulation, ASIC implementation, and FPGA experiment, which exhibits high performance and potential for a gigahertz range,low-power monolithic CMOS frequency synthesizer.展开更多
Based on the overall consideration of individual behaviors of Ricardian and non-Ricardian households, this paper develops a New Keynesian dynamic stochastic general equilibrium(DSGE) model to form a relatively systema...Based on the overall consideration of individual behaviors of Ricardian and non-Ricardian households, this paper develops a New Keynesian dynamic stochastic general equilibrium(DSGE) model to form a relatively systematic research framework for analyzing the economic effects of structural fiscal instruments. Our study findsthat great differences exist in the macroeconomic effects of different fiscal instruments, suggesting that the government should prudently select these fiscal instruments in fiscal macro-control. The simulating results of fiscal shocks show that the effect of tax cut is superior to the effect of increased spending. In the context of slowing economic growth and less potent stimulation policy, the government should transform its previous regulatory approach of fiscal policy and shift from hefty spending stimulus policy to structural tax cuts. This paper believes that China should step up the implementation of public-private partnership, increase its spending on social security, healthcare, pension and public services and facilitate the transition toward a service-based government; and that tax policy should focus on structural tax cuts on consumption to promote the transition of demand structure toward consumption-driven.展开更多
The equivalent refractive index(ERI) method is employed to analyze the function of the strip waveguide directional coupling modulator(SWM). Through deducing the diagnostic equation of the Exmn mode of the four-lay...The equivalent refractive index(ERI) method is employed to analyze the function of the strip waveguide directional coupling modulator(SWM). Through deducing the diagnostic equation of the Exmn mode of the four-layer media film waveguide equivalent to the SWM,the transmission constant of the symmetrical mode of the positive phase and negative one and the coupling length of powerful transference are obtained. The veracity of ERI is validated with the example of Ex11 basal mode under conditions of comparing the three results of ERI,EIM and Marcatili.展开更多
AIM:To characterize the differentially expressed gene profiles in livers from biliary atresia (BA) patients including,ascertain genes,functional categories and pathways that play a central role in the pathogenesis of ...AIM:To characterize the differentially expressed gene profiles in livers from biliary atresia (BA) patients including,ascertain genes,functional categories and pathways that play a central role in the pathogenesis of BA,and identify the novel prognostic markers for BA.METHODS:Liver tissue samples from control patients,neonatal cholestasis patients,and BA patients at the age of < 60 d,60-90 d,and > 90 d were pooled for DNA microarray analysis.Bioinformatics analysis was performed using,series test cluster of gene ontology,and Pathway-Finder software.Reverse-transcription polymerase chain reaction was performed to confirm changes in selected genes.Relation between RRAS gene expression and prognosis of 40 BA patients was analyzed in a 2-year follow-up study.RESULTS:The 4 identified significant gene expression profiles could confidently separate BA liver tissue from normal and other diseased liver tissues.The included genes were mainly involved in inflammation response and reconstruction of cellular matrix.The significant pathways associated with BA were primarily involved in autoimmune response,activation of T lymphocytes and its related cytokines.The RRAS,POMC,SLC26A6 and STX3 genes were important regulatory modules in pathogenesis of BA.The expression of RRAS was negatively correlated with the elimination rate of jaundice and positively correlated with the occurrence rate of cholangitis.CONCLUSION:Autoimmune response mediated by T lymphocytes may play a vital role in the pathogenesis of BA.The RRAS gene is an important regulatory module in the pathogenesis of BA,which may serve as a novel prognostic marker for BA.展开更多
The transparent solid medium of a thermotropic liquid crystal polymer have a comb structure of mesogenic side chains which exhibit a nonlinear optical response of electronic origin.The main chain of the liquid crystal...The transparent solid medium of a thermotropic liquid crystal polymer have a comb structure of mesogenic side chains which exhibit a nonlinear optical response of electronic origin.The main chain of the liquid crystal polymers can be selected from a number of suitable polymerized monomeric and comonomeric structures such as polyvinyl,polysiloxane,polyoxyalkylene, polyester etc.The electrooptic light modulator is provided,which have potential to using in the systems of laser modulation and deflection,and information control in optical circuitry etc.展开更多
文摘Crystalline@amorphous NiCo_(2)S_(4)@MoS_(2)(v-NCS@MS)nanostructures were designed and constructed via an ethylene glycol-induced strategy with hydrothermal synthesis and solvothermal method,which simultaneously realized the defect regulation of crystal NiCo_(2)S_(4) in the core.Taking advantage of the flexible protection of an amor-phous shell and the high capacity of a conductive core with defects,the v-NCS@MS electrode exhibited high specif-ic capacity(1034 mAh·g^(-1) at 1 A·g^(-1))and outstanding rate capability.Moreover,a hybrid supercapacitor was assembled with v-NCS@MS as cathode and activated carbon(AC)as anode,which can achieve remarkably high specific energy of 111 Wh·kg^(-1) at a specific power of 219 W·kg^(-1) and outstanding capacity retention of 80.5%after 15000 cycling at different current densities.
文摘A new FM transmitter is reported. It adopts a fractional-N PLL synthesizer to realize the FM modulator. An extra offset current has also been applied to eliminate the effects of the mismatch in CP. The chip is fabricated with CSMC 0.5μm DPTM CMOS technology. Experiments show that it achieves THD≤0.08% and SNR≤ 82dB,and the maximum outband emission energy ≤ 90dBc/Hz. Furthermore,it also uses an auto frequency adjusting method to avoid tuning up the external inductances. All these merits are very suitable for FM transmission.
文摘The oil film clutch, which is superior in speed adjustment, is capable of being used in the belt conveyor to carry out soft start operation. According to running properties of both belt conveyor and oil film clutch, equations that are used to decide the lubricating oil flow and the number of oil films (i.e. the number of rotating and stationary plates) are deduced theoretically. Also key parameters are provided for the design of the hydraulic system. All these together provide the theoretical basis for the soft start design of the belt conveyor and references for the application of the oil film clutch in similar fields.
文摘Two different poling techniques-corona poling and contact poling in the backdrop of electro-optic (EO) polymer modulators are compared. A 3-layer structure EO polymer modulator is prepared for the poling. The poling setups and procedures of these two different methods are given. It is found that a well-controlled precure step is very critical, otherwise it will result in either lower poling efficiency or damaged film. Experimental results show that contact poling does not create severe surface damage as corona poling and poling voltage is much lower, but corona poling provides higher EO effect than contact poling. Besides, contact poling can provide poling size as large as the substrate size.
文摘A Mach-Zehnder(MZ) electro-optic(EO) modulator are real iz ed,with three optical layers as polymer materials.The functional layer is the co rona poled crosslinkable polyurethane.The ridge waveguide is fabricated by using the spin-coating,poling,photolithography and oxygen reactive ion etching(RIE) techniques.The mode and the modulation properties of these devices are demonstra ted in a micron control system,while the light source works at the wavelength of 1 31 or 1 55 micron.
文摘A new coarse tuning loop for a wide-band dual-loop frequency synthesizer is presented. The coarse tuning structure is composed of two digital modules, including a successive approximation register and a frequency comparator with a novel structure. The frequency comparator counts the prescaler cycles within a certain reference time and compares the number with preset data to estimate the VCO frequency. The frequency comparison error is analyzed in detail. Within a given coarse tuning time,our proposed structure shows a comparison error 20 times smaller than that of other reported structures. This structure also reuses the programmable divider as a part of the coarse tuning loop so that the circuit is greatly simplified.
基金National Natural Science Foun-dation of China (No.60468001)
文摘The nonlinear coupled-mode equations are rewritten by even and odd modes.We study modulation instability(MI) of dispersion-shifted fiber couplers when either even or odd mode is launched alone by using zero-dispersion wavelength relatively long(quasi-cw) pulses.The result shows that there are new types of MI in both the normal-dispersion and the anomalous-dispersion regimes.MI is concerned with forth-order dispersion and has no relation with third-order dispersion.Quasi-cw can be changed into pulses array under certain conditions.We can extract super short pulse from this.Furthermore,the bandwidth of gain spectra widens and its strength accretes as the input power increases.
文摘Several drugs are used in the treatment of irritable bowel syndrome (IBS) but all have side effects and variable efficacy. Considering the role of the gut-brain axis, immune, neural, and endocrine pathways in the patho- genesis of IBS and possible beneficial effects of benzodiazepines (BZD) in this axis, the present systematic review focuses on the efficacy of BZD receptor modulators in human IBS. For the years 1966 to February 2011, all literature was searched for any articles on the use of BZD receptor modulators and IBS. After thorough evaluation and omission of duplicate data, 10 out of 69 articles were included. BZD receptor modulators can be helpful, especially in the diarrhea-dominant form of IBS, by affecting the inflammatory, neural, and psychologic pathways, however, controversies still exist. Recently, a new BZD receptor modulator, dextofisoparn was synthesized and studied in human subjects, but the studies are limited to phase 11 b clinical trials. None of the existing trials considered the neuroimmunomodulatory effect of BZDs in IBS, but bearing in mind the concentration- dependent effect of BZDs on cytokines and cell proliferation, future studies using pharmacodynamic and pharmacokinetic approaches are highly recommended.
基金supported jointly by the National Basic Research Program of China(Grant Nos.2012CB955303 and 2013CB955803)the Chinese Academy of Sciences Ocean Project(Grant No.XDA11010402)+1 种基金the National Natural Science Foundation of China(Grant Nos.41175059 and 41375087)the Key Laboratory of Meteorological Disaster of Ministry of Education(Nanjing University of Information Science and Technology)(Grant No.KLME1409)
文摘Cloud radiative effects (CREs) at the top of the atmosphere (TOA) in three reanalysis datasets (the Eur- opean Center for Medium-Range Weather Forecasts In- terim Reanalysis (ERA-Interim), the Japanese 55-yr Re- analysis Project (JRA-55), and the Modem-Era Retro- spective Analysis for Research and Applications (MERRA)) are evaluated using recent satellite-based observations. The reanalyses can basically capture the spatial pattern of the annual mean shortwave CRE, but the global mean longwave CRE in ERA-interim and JRA55 is weaker than observed, leading to overestimations of the net CRE. Moreover, distinct CRE biases of the reanalyses occur in the Intertropical Convergence Zone (ITCZ), coastal Pa- cific and Atlantic regions, and East Asia. Quantitative examination further indicates that the spatial correlations of CREs and TOA upward radiation fluxes with corre- sponding observations in ERA-Interim are better than in the other two reanalyses. Although MERRA has certain abilities in producing the magnitudes of global mean CREs, its performance in terms of spatial correlations in winter and summer are worse than for the other two re- analyses. The ability of JRA55 in reflecting CREs lies between the other two datasets. Compared to the global mean results, the spatial correlations of shortwave CRE in East Asia decrease and the biases of regional mean CREs increase in the three reanalyses. This implies that, cur- rently, it is still difficult to reproduce East Asian CREs based on these reanalyses. Relatively, ERA-Interim de- scribes the seasonal variation of East Asian CREs well, albeit weaker than observed. The present study also sug- gests that in-depth exploration of the ability of reanalysis data to describe aspects relating to cloud properties and rad- iation is needed usin~ more comprehensive observations.
文摘This paper presents the design considerations and implementation of a novel topology digital multistage-noise-shaping (MASH) delta-sigma modulator suitable for fractional-N phase-locked-loop (PLL) frequency synthesis. In an effort to reduce the complexity and dissipation,a pipeline technique has been used, and the proposed carry save tree (CST) algorithm optimizes the multi-input adder structure. The circuit has been verified through Matlab simulation, ASIC implementation, and FPGA experiment, which exhibits high performance and potential for a gigahertz range,low-power monolithic CMOS frequency synthesizer.
文摘Based on the overall consideration of individual behaviors of Ricardian and non-Ricardian households, this paper develops a New Keynesian dynamic stochastic general equilibrium(DSGE) model to form a relatively systematic research framework for analyzing the economic effects of structural fiscal instruments. Our study findsthat great differences exist in the macroeconomic effects of different fiscal instruments, suggesting that the government should prudently select these fiscal instruments in fiscal macro-control. The simulating results of fiscal shocks show that the effect of tax cut is superior to the effect of increased spending. In the context of slowing economic growth and less potent stimulation policy, the government should transform its previous regulatory approach of fiscal policy and shift from hefty spending stimulus policy to structural tax cuts. This paper believes that China should step up the implementation of public-private partnership, increase its spending on social security, healthcare, pension and public services and facilitate the transition toward a service-based government; and that tax policy should focus on structural tax cuts on consumption to promote the transition of demand structure toward consumption-driven.
文摘The equivalent refractive index(ERI) method is employed to analyze the function of the strip waveguide directional coupling modulator(SWM). Through deducing the diagnostic equation of the Exmn mode of the four-layer media film waveguide equivalent to the SWM,the transmission constant of the symmetrical mode of the positive phase and negative one and the coupling length of powerful transference are obtained. The veracity of ERI is validated with the example of Ex11 basal mode under conditions of comparing the three results of ERI,EIM and Marcatili.
基金Supported by National Natural Science Foundation of China,No.30973139
文摘AIM:To characterize the differentially expressed gene profiles in livers from biliary atresia (BA) patients including,ascertain genes,functional categories and pathways that play a central role in the pathogenesis of BA,and identify the novel prognostic markers for BA.METHODS:Liver tissue samples from control patients,neonatal cholestasis patients,and BA patients at the age of < 60 d,60-90 d,and > 90 d were pooled for DNA microarray analysis.Bioinformatics analysis was performed using,series test cluster of gene ontology,and Pathway-Finder software.Reverse-transcription polymerase chain reaction was performed to confirm changes in selected genes.Relation between RRAS gene expression and prognosis of 40 BA patients was analyzed in a 2-year follow-up study.RESULTS:The 4 identified significant gene expression profiles could confidently separate BA liver tissue from normal and other diseased liver tissues.The included genes were mainly involved in inflammation response and reconstruction of cellular matrix.The significant pathways associated with BA were primarily involved in autoimmune response,activation of T lymphocytes and its related cytokines.The RRAS,POMC,SLC26A6 and STX3 genes were important regulatory modules in pathogenesis of BA.The expression of RRAS was negatively correlated with the elimination rate of jaundice and positively correlated with the occurrence rate of cholangitis.CONCLUSION:Autoimmune response mediated by T lymphocytes may play a vital role in the pathogenesis of BA.The RRAS gene is an important regulatory module in the pathogenesis of BA,which may serve as a novel prognostic marker for BA.
文摘The transparent solid medium of a thermotropic liquid crystal polymer have a comb structure of mesogenic side chains which exhibit a nonlinear optical response of electronic origin.The main chain of the liquid crystal polymers can be selected from a number of suitable polymerized monomeric and comonomeric structures such as polyvinyl,polysiloxane,polyoxyalkylene, polyester etc.The electrooptic light modulator is provided,which have potential to using in the systems of laser modulation and deflection,and information control in optical circuitry etc.