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森林系统对降雨径流的调节转换规律研究 被引量:1
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作者 雷孝章 曹叔尤 江小华 《中国水土保持科学》 CSCD 2008年第z1期24-29,共6页
为研究森林系统对降雨径流的调节、转换和再分配功能,根据生态系统的结构,分层次设置监测系统,监测单因子或单项因子在生态系统中的变化趋势,揭示各因子在生态系统中的"独立"作用;随着流域系统的扩大,研究因子的组合作用,以... 为研究森林系统对降雨径流的调节、转换和再分配功能,根据生态系统的结构,分层次设置监测系统,监测单因子或单项因子在生态系统中的变化趋势,揭示各因子在生态系统中的"独立"作用;随着流域系统的扩大,研究因子的组合作用,以及对流域系统的终极响应,由此可揭示森林系统藕合后对流域(区域)径流的调节、转换和再分配规律。 展开更多
关键词 森林 生态系统 径流 调节转换 藕合
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LT1074降压转换调节器的特点及应用 被引量:1
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作者 陈慧 霍家道 +1 位作者 袁瑞铭 袁赣南 《应用科技》 CAS 2001年第8期39-40,共2页
在一些工业控制环境下的微测控电路单元往往要求 +5V的工作电压 ,而实际场所很难满足这一要求 ,如汽车中提供的电压为 12V~ 14V。而LT10 74降压转换调节器可以提供稳定的 +5V电压。介绍了LT10 74降压转换调节器的特点和性能 ,并给了应... 在一些工业控制环境下的微测控电路单元往往要求 +5V的工作电压 ,而实际场所很难满足这一要求 ,如汽车中提供的电压为 12V~ 14V。而LT10 74降压转换调节器可以提供稳定的 +5V电压。介绍了LT10 74降压转换调节器的特点和性能 ,并给了应用于车辆监控系统中的实例。 展开更多
关键词 降压转换调节 车辆监控 GPS GIS LT1074型 应用 车辆监控系统
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强迫症患者的注意转换及在线元认知调节 被引量:1
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作者 程素萍 徐礼鹏 《应用心理学》 CSSCI 2012年第2期173-185,共13页
为探索强迫症患者是否同时存在注意转换和在线元认知调节障碍,本研究使用线索性任务转换范式及数字跟踪击键范式并结合ERP数据,对16名强迫症患者的注意转换能力和在线元认知调节能力进行了评价。结果表明,强迫症患者同时存在注意转换及... 为探索强迫症患者是否同时存在注意转换和在线元认知调节障碍,本研究使用线索性任务转换范式及数字跟踪击键范式并结合ERP数据,对16名强迫症患者的注意转换能力和在线元认知调节能力进行了评价。结果表明,强迫症患者同时存在注意转换及在线元认知调节的缺陷。 展开更多
关键词 OCD注意转换在线元认知调节元认知模型
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森林对降雨径流的调蓄转换规律研究 被引量:9
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作者 雷孝章 王金锡 赵文谦 《四川林业科技》 北大核心 2000年第2期7-12,共6页
本文通过分析森林不同层次对降雨径流的调节转换规律 ,建立相应模型 ,并根据不同尺度下坡面流的产汇流特点 ,建立流域森林水文模型。从四个流域的模拟结果看 ,森林对流域降雨径流调节。
关键词 森林水文模型 降雨径流 调节转换规律
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Microchip Technology进一步扩展电源管理系列推出120毫安可调节无电感电荷泵直流—直流转换器
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《单片机与嵌入式系统应用》 2003年第2期69-69,共1页
Microchip Technology推出新款可调节电荷泵直流—直流转换器,进一步扩展其电源。 管理产品系列。型号为MCP1252和MCP1253的新器件是120mA可调节电荷泵器件,采用8管脚MSOP封装,工作温度从-40℃~85℃。使用户可以得到一种能节省线路板... Microchip Technology推出新款可调节电荷泵直流—直流转换器,进一步扩展其电源。 管理产品系列。型号为MCP1252和MCP1253的新器件是120mA可调节电荷泵器件,采用8管脚MSOP封装,工作温度从-40℃~85℃。使用户可以得到一种能节省线路板空间的电源管理产品,在电池供电的环境下可完成直流到直流的转换,而无需使用电感器。 展开更多
关键词 MicrochipTechnology 电源管理 120毫安可调节无电感电荷泵直流-直流转换
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治疗期儿童青少年恶性肿瘤患儿社会适应相关因素分析 被引量:7
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作者 刘倩 莫霖 +2 位作者 黄先巧 余璐 刘洋 《中国卫生统计》 CSCD 北大核心 2021年第3期391-395,共5页
目的探索治疗期儿童青少年恶性肿瘤患儿应对方式、社会支持与社会适应的关系及自我效能感和创伤后成长的中介作用。方法采用简易方式问卷、社会关系网络问卷、一般自我效能感量表、创伤后成长评定量表、抑郁-焦虑-压力量表和Conners父... 目的探索治疗期儿童青少年恶性肿瘤患儿应对方式、社会支持与社会适应的关系及自我效能感和创伤后成长的中介作用。方法采用简易方式问卷、社会关系网络问卷、一般自我效能感量表、创伤后成长评定量表、抑郁-焦虑-压力量表和Conners父母用症状量表对163名治疗期儿童青少年恶性肿瘤患儿进行调查。结果女性患儿的负性情绪水平相对较高而行为问题较少,权威型、专制型教养方式患儿的负性情绪水平较低。相关分析表明,应对方式、自我效能感、创伤后成长均与负性情绪和行为问题呈显著负相关;社会支持中,肯定与支持维度、陪伴与亲密维度与负性情绪、行为问题呈显著负相关,满意度维度与抑郁、品行行为和心身障碍维度呈显著负相关,冲突与惩罚维度与抑郁、品行行为维度呈显著正相关。链式中介效应分析表明自我效能感和创伤后成长在应对方式、社会支持和负性情绪、行为问题之间具有链式中介的作用。结论治疗期儿童青少年恶性肿瘤患儿应对方式和社会支持通过自我效能感或创伤后成长的单独中介作用以及自我效能感和创伤后成长的链式中介作用间接负向预测负性情绪或行为问题。 展开更多
关键词 恶性肿瘤 青少年 儿童 社会适应 自我调节转换理论
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由《尤利西斯》中译本看小说翻译中叙事视角的传译 被引量:8
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作者 申迎丽 孙致礼 《解放军外国语学院学报》 北大核心 2004年第5期51-57,共7页
叙事视角在小说尤其是现代小说中是一种极为重要的叙事技巧。小说叙述者在主要使用一种视角叙述的同时,往往会对视角进行多样化的调节,其中包括暂时使用人物视角、运用摄像式的旁观视角等以配合小说主题并取得一定的叙事效果。小说翻译... 叙事视角在小说尤其是现代小说中是一种极为重要的叙事技巧。小说叙述者在主要使用一种视角叙述的同时,往往会对视角进行多样化的调节,其中包括暂时使用人物视角、运用摄像式的旁观视角等以配合小说主题并取得一定的叙事效果。小说翻译中译者应注意并准确传达原文视角的转换调节,避免呈现给读者"假象等值"的译文。 展开更多
关键词 尤利西斯 叙事视角 视角转换调节 小说翻译 假象等值
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The microcell mediated transfer of human chromosome 8 into highly metastatic rat liver cancer cell line C5F 被引量:6
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作者 Hu Liu Sheng-Long Ye Jinng Yang Zhao-You Tang Yin-Kun Liu Lun-Xiu Qin Shuang-Jian Qiu Rui-Xia Sun Liver Cancer Institute, Zhong Shan Hospital, Fudan University, Shanghai 200032, China 《World Journal of Gastroenterology》 SCIE CAS CSCD 2003年第3期449-453,共5页
AIM: Our previous research on the surgical samples of primary liver cancer with CGH showed that the loss of human chromosome 8p had correlation with the metastatic phenotype of liver cancer. In order to seek the funct... AIM: Our previous research on the surgical samples of primary liver cancer with CGH showed that the loss of human chromosome 8p had correlation with the metastatic phenotype of liver cancer. In order to seek the functional evidence that there could be a metastatsis suppressor gene (s) for liver cancer on human chromosome 8, we tried to transfer normal human chromosome 8 into rat liver cancer cell line C5F, which had high metastatic potential to lung.METHODS: Human chromosome 8 randomly marked with neo gene was introduced into C5F cell line by MMCT and positive microcell hybrids were screened by double selections of G418 and HAT. Single cell isolation cloning was applied to clone microcell hybrids. Finally, STS-PCR and WCP-FISH were used to confirm the introduction.RESULTS: Microcell hybrids resistant to HAT and G418 were obtained and 15 clones were obtained by single-cell isolation cloning. STS-PCR and WCP-FISH proved that human chromosome 8 had been successfully introduced into rat liver cancer cell line C5F. STS-PCR detected a random loss in the chromosome introduced and WCP-FISH found a consistent recombination of the introduced human chromosome with the rat chromosome.CONCLUSION: The successful introduction of human chromosome 8 into highly metastatic rat liver cancer cell line builds the basis for seeking functional evidence of a metastasis suppressor gene for liver cancer harboring on human chromosome 8 and its subsequent cloning. 展开更多
关键词 C5F细胞系 肝癌 动物模型 微细胞调节转换 人染色体8 肿瘤转移
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基于PROSPECT+SAIL模型反演叶面积指数的较强适用性植被指数的筛选 被引量:6
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作者 赵虹 鲁蕾 颉耀文 《兰州大学学报(自然科学版)》 CAS CSCD 北大核心 2014年第1期89-94,100,共7页
基于PROSPECT+SAIL植被辐射传输模型,通过控制不同的植被生化变量、地表参数和土壤光谱参数建立光谱数据集,定量地分析了归一化植被指数(NDVI)、比值植被指数(SR)、土壤调节植被指数(SAVI)等10种常用的植被指数(VIs)对叶面积指数(LAI)... 基于PROSPECT+SAIL植被辐射传输模型,通过控制不同的植被生化变量、地表参数和土壤光谱参数建立光谱数据集,定量地分析了归一化植被指数(NDVI)、比值植被指数(SR)、土壤调节植被指数(SAVI)等10种常用的植被指数(VIs)对叶面积指数(LAI)的响应.利用敏感性函数定量地筛选出具有较强适用性的转换型土壤调节植被指数(TSAVI).在此基础上,分别建立了TSAVI及常用植被指数NDVI反演LAI的模型.以张掖市南部地区的TM影像为数据源,进行了LAI的反演,并利用黑河生态水文遥感试验获得的中游LAI数据集对模型进行精度评价.结果表明:TSAVI–LAI模型最佳拟合关系为指数形式,其反演结果与LAI实测值的偏差最小(0.200),R2最大(0.686),RMSE最小(0.397).TSAVI可以作为较强适用性植被指数来进行LAI的反演. 展开更多
关键词 PROSPECT+SAIL模型 叶面积指数 敏感性函数 转换型土壤调节植被指数
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Inhibitory effect of adeno-associated virus-mediated gene transfer of human endostatin on hepatocellular carcinoma 被引量:11
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作者 HongLiu Ying-BinLiu +4 位作者 Yu-LianWu Zhi-MingZhao YongWang Bao-SanHan Cheng-HongPeng 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第22期3331-3334,共4页
AIM: To investigate the effect of adeno-associated virusmediated gene transfer of human endostatin on the growth of hepatocellular carcinoma (HCC).METHODS: HCC cell line Hep3B was infected with recombinantadeno-associ... AIM: To investigate the effect of adeno-associated virusmediated gene transfer of human endostatin on the growth of hepatocellular carcinoma (HCC).METHODS: HCC cell line Hep3B was infected with recombinantadeno-associated virus containing human endostatin gene (rAAV2-hEndo). The results of transfection were detected by RT-PCR and SDS-PAGE assay. MTT assay was used to observe the effects of supernatant of transfected cells on ECV304 cell proliferation. An animal model of HCC was established by injecting Hep3B cells subcutaneously into the back of nude mice. Intratumoral injection of rAAV2hEndo, empty virus and phosphate-buffered saline were given sequentially. Serum endostatin was determined byELISA, the inhibitory effect of endostatin on the growth of xenograft was assessed in 3 wk.RESULTS: The results of RT-PCR and SDS-PAGE assay confirmed that rAAV2-hEndo successfully transfected Hep3B cells, and endostatin was secreted from Hep3B cells to medium. The supernatant of transfected cells markedly inhibited the proliferation of ECV304 cells (P<0.01). Intratumoral injection of rAAV2-hEndo (2×1010v.g.) led to a sustained serum endostatin level ofapproximately (86.71±5.19) ng/mL. The tumor volumeand microvessel density were less in rAAV2-hEndo group than in control groups (P<0.01).CONCLUSION: Human endostatin can be stably expressed by adeno-associated virus-mediated gene transfer and effectively inhibit the growth of HCC. 展开更多
关键词 ENDOSTATIN GENE Adeno-associated virus Hepatocellular carcinoma
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The research of power saving frequency conversion speed regulation experiment system
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作者 仲伟堂 《Journal of Coal Science & Engineering(China)》 2008年第1期152-156,共5页
A power saving frequency difference controlling method was introduced by the double inverter and motor experiment system.The characters of the system under differ- ent loads were investigated.The theoretical analysis ... A power saving frequency difference controlling method was introduced by the double inverter and motor experiment system.The characters of the system under differ- ent loads were investigated.The theoretical analysis and experiment results show the frequency difference method is a ideal power saving speed regulation method for the dou- ble inverter and motor system.The experiment system is simply structured,convenient to operate and provides a new way of character testing for frequency conversion speed regulation. 展开更多
关键词 power saving speed regulation asynchronous motor frequency differencecontrolling
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米诺地尔对血管平滑肌细胞迁移及高血压相关基因离子转换调节器5表达的影响
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作者 拜文廉 马玉民 马进才 《中国临床药理学杂志》 CAS CSCD 北大核心 2023年第3期359-362,共4页
目的 探究米诺地尔对血管平滑肌细胞迁移及高血压相关基因离子转换调节器5(FXYD5)表达的影响。方法 体外培养人主动脉血管平滑肌细胞(HASMC),并分为空白组(正常培养HASMC细胞)及低、中、高剂量实验组(分别加入含终浓度为0.1,0.5和1.0 mm... 目的 探究米诺地尔对血管平滑肌细胞迁移及高血压相关基因离子转换调节器5(FXYD5)表达的影响。方法 体外培养人主动脉血管平滑肌细胞(HASMC),并分为空白组(正常培养HASMC细胞)及低、中、高剂量实验组(分别加入含终浓度为0.1,0.5和1.0 mmol·L^(-1)米诺地尔溶液的不含胎牛血清、含90%高糖的DMEM培养基)。用划痕实验检测各组HASMC细胞的迁移能力,用蛋白质印迹法检测FXYD5、N-钙黏附蛋白(N-cadherin)、Ras同族体基因家族成员A(RhoA)和Rho激酶1(ROCK1)蛋白的表达情况。结果 中、高剂量实验组和空白组的划痕愈合率分别为(45.96±6.85)%,(30.15±4.38)%和(78.94±9.76)%,FXYD5蛋白相对表达水平分别为0.53±0.08,0.16±0.03和1.13±0.16,N-Cadherin蛋白相对表达水平分别为0.45±0.08,0.20±0.03和0.98±0.15,RhoA蛋白相对表达水平分别为0.47±0.08,0.20±0.03和1.06±0.16,ROCK1蛋白相对表达水平分别为0.77±0.12,0.36±0.05和1.25±0.19。中、高剂量实验组的上述指标与空白组比较,差异均有统计学意义(均P<0.05)。结论 米诺地尔可通过下调FXYD5表达,抑制RhoA/ROCK通路活化,从而实现对血管平滑肌细胞增殖和迁移的抑制作用。 展开更多
关键词 米诺地尔 血管平滑肌细胞 迁移 离子转换调节器5
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Optical A/D Quantizer Scheme Based on Parallel Phase Mod ulators
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作者 LI Zheng 《Semiconductor Photonics and Technology》 CAS 2005年第3期161-165,共5页
A high-speed and high-resolution optical A/D quantizer is proposed.Its architecture is discussed.Bit circuits are built by using the phase modulators in parallel.Based on the different character of the half-wave volta... A high-speed and high-resolution optical A/D quantizer is proposed.Its architecture is discussed.Bit circuits are built by using the phase modulators in parallel.Based on the different character of the half-wave voltage for every phase modulator and the polarized bias design of incident light,the RF input signal is coled and transmitted in the form of optical digital signal.According to the principle of the architecture,the high-resolution quantizers with 8-bit and 12-bit,et al.are built,which operate at 100 GS/s.Their quantization noise is invariable almost with bit circuits increasing.The simulation result of 4-bit A/D quantizer is also given. 展开更多
关键词 Optical A/D quantizer PARALLEL Photonic sampling Optical data processing Traveling wave phase modulation
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雄激素与骨质疏松 被引量:3
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作者 杨庆秋 胡侦明 劳汉昌 《中华外科杂志》 CAS CSCD 北大核心 2001年第1期83-85,共3页
关键词 骨质疏松 雄激素 骨细胞调节 骨量调节 转换调节
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转录因子E2F-3靶向FOSB对结直肠癌细胞增殖、迁移和侵袭的影响
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作者 林传俊 裴富雍 +7 位作者 赵小乐 余晓明 王国洲 姜进平 汤守元 罗海平 兰国玉 程伏林 《中华实验外科杂志》 CAS 北大核心 2023年第9期1761-1764,共4页
目的探究转录因子E2F-3对结直肠癌细胞增殖、迁移和侵袭的影响。方法在体外培养人的结直肠癌细胞系RKO、SW480、DLD1、LOVO和人的结肠正常上皮细胞NCM460,并用反转录实时荧光定量聚合酶链反应(RT-qPCR)检测结肠上皮细胞NCM460和结直肠... 目的探究转录因子E2F-3对结直肠癌细胞增殖、迁移和侵袭的影响。方法在体外培养人的结直肠癌细胞系RKO、SW480、DLD1、LOVO和人的结肠正常上皮细胞NCM460,并用反转录实时荧光定量聚合酶链反应(RT-qPCR)检测结肠上皮细胞NCM460和结直肠癌细胞SW480、RKO、DLD1、LOVO中E2F-3的转录水平。分别将E2F-3的siRNA-E2F3和siRNA-NC阴性对照转染于细胞系RKO中,设为实验组(si-E2F3)与阴性对照组(NC)。采用平板克隆实验细胞与细胞计数试剂盒(CCK-8)检测细胞增殖活性。Transwell迁移和侵袭实验与细胞划痕实验用来检测细胞的迁移及侵袭能力。RT-qPCR和蛋白质印迹法(Western blot)分别可以检测E2F-3靶向蛋白FOSB的表达水平。两样本间对比采取t检验,多组间差异采用单因素方差分析。结果miR-210-3p在结直肠癌细胞系中表达均高于人正常结肠上皮细胞,其中以RKO中升高最为明显,相较NC[(2.349±0.095)倍比(1.000±0.013)倍,t=65.82,P<0.01],差异有统计学意义。转染si-E2F3后,敲降组si-E2F3表达水平显著降低[(0.394±0.010)倍比(1.000±0.013)倍,t=66.38,P<0.01],差异有统计学意义。CCK-8实验表明si-E2F3组在不同时间段吸光度值均低于NC组[(0.720±0.110)倍比(1.210±0.015)倍,t=19.65,P<0.01],差异有统计学意义。细胞克隆实验结果显示,si-E2F3组细胞克隆形成能力低于NC组[(171.000±4.000)倍比(317.000±8.000)倍,t=19.75,P<0.01],差异有统计学意义。划痕愈合实验结果表明,si-E2F3组划痕愈合百分比低于NC组[(0.163±0.004)倍比(0.244±0.013)倍,t=9.39,P<0.01],差异有统计学意义。Transwell侵袭实验结果显示,si-E2F3组细胞中穿出的细胞数低于NC组[(53.667±4.667)倍比(161.67±4.333)倍,t=30.89,P<0.01],差异有统计学意义。Transwell迁移实验结果表明:si-E2F3组细胞迁移细胞数低于NC组[(52.333±5.333)倍比(99.333±5.333)倍,t=11.79,P<0.01],差异有统计学意义。通过生物信息学分析筛选出E2F-3靶蛋白FOSB,Western blot结果表明转染了si-E2F3后,结直肠癌细胞中FOSB表达量显著降低。结论E2F-3在人的结直肠癌细胞系中显著高表达,其中以RKO最为显著,并可能通过靶向FOSB促进结直肠癌细胞的增殖、迁移和侵袭。 展开更多
关键词 结直肠癌 转录因子 G 0/G1转换调节蛋白3
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Transcriptional regulatory circuits controlling muscle fiber type switching 被引量:3
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作者 LIU Jing LIANG XiJun GAN ZhenJi 《Science China(Life Sciences)》 SCIE CAS CSCD 2015年第4期321-327,共7页
Skeletal muscle fitness plays vital roles in human health and disease and is determined by developmental as well as physiological inputs. These inputs control and coordinate muscle fiber programs, including capacity f... Skeletal muscle fitness plays vital roles in human health and disease and is determined by developmental as well as physiological inputs. These inputs control and coordinate muscle fiber programs, including capacity for fuel burning, mitochondrial ATP production, and contraction. Recent studies have demonstrated crucial roles for nuclear receptors and their co-activators, and micro RNAs(mi RNAs) in the regulation of skeletal muscle energy metabolism and fiber type determination. In this review, we present recent progress in the study of nuclear receptor signaling and mi RNA networks in muscle fiber type switching. We also discuss the therapeutic potential of nuclear receptors and mi RNAs in disease states that are associated with loss of muscle fitness. 展开更多
关键词 fiber type switching gene regulation MUSCLE nuclear receptor MICRORNA
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Photoresponsive nucleic acids for gene regulation
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作者 苏蒙 杨帆 +5 位作者 吕聪 余丽丽 顾笑岩 王颉 李仲瑾 汤新景 《Journal of Chinese Pharmaceutical Sciences》 CAS 2010年第1期5-14,共10页
For the main purpose of manipulating the functions of molecules, researchers have made great achievements on photoresponsive molecules using light as a trigger. Light has become a promising scientific tool due to it b... For the main purpose of manipulating the functions of molecules, researchers have made great achievements on photoresponsive molecules using light as a trigger. Light has become a promising scientific tool due to it being a clean and noninvasive external stimulant. By attachment of photoresponsive moieties to molecules, the biological activities of molecules can be attenuated by light activation. With wide applications of laser in life sciences, it will be possible to achieve high spatiotemporal resolution. In this review, we focus on photoresponsive nucleic acids for photomodulating gene expression with light activation. With incorporation of photoswitchable or photocleavable moieties, biological behaviors of nucleic acids are photoregulated reversibly or irreversibly. Recent development and applications of photoresponsive nucleic acid in vitro and in vivo have shown a very promising future for manipulation of specific functional genes or disease genes. We expect that photoresponsive nucleic acids will be powerful scientific tools for studying biological events as well as gene therapy agents for genetic diseases. 展开更多
关键词 Photoresponsive Caging group Photoswitchable Gene regulation Oligonucleotide
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Diyne-linked and fully π-conjugated polymetalloporphyrin nanosheets for outstanding heterogeneous catalysis 被引量:1
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作者 Kun Li Ziping Li +3 位作者 Yongfeng Zhi Hong Xia Yuwei Zhang Xiaoming Liu 《Science Bulletin》 SCIE EI CSCD 2021年第4期354-361,M0004,共9页
Two-dimensional,ultrathin,robust,and fullyπ-conjugated organic nanomaterials are highly desirable for application in various fields due to their unique photoelectric characteristics and great number of exposed active... Two-dimensional,ultrathin,robust,and fullyπ-conjugated organic nanomaterials are highly desirable for application in various fields due to their unique photoelectric characteristics and great number of exposed active sites.However,such matters combining excellent stability,fullπ-conjugation and adjustability are rare,which has become a bottleneck for their practical application.Herein,we present a novel kind of diyne-linked polymetalloporphyrin nanosheet featuring permanent porosity and fullπ-conjugation,which exhibits a high-aspect-ratio,outstanding stability and convenient tailoring for electronic structures.Importantly,the novel nanosheets with monodisperse nickel atoms were found to be outstanding heterogeneous catalyst with unprecedented catalytic activity and selectivity for 4-nitrophenol reduction to 4-aminophenol under mild conditions.The findings recommend that diynelinked polymetalloporphyrin nanosheets may offer new platforms for the conversion of photoelectricity and energy in the future. 展开更多
关键词 Covalent organic nanosheets Polymetalloporphyrin nanomaterials Heterogeneous catalysts Reduction reaction
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