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基于SNP标记的玉米自交系类群划分方法和分群功效评估指标的比较 被引量:3
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作者 李念念 王义波 +4 位作者 徐国平 易黎 王爱方 李婷 曹刚强 《植物遗传资源学报》 CAS CSCD 北大核心 2020年第3期605-615,共11页
随着高通量测序技术的不断进步带来的SNP标记成本的持续下降,可用于种质资源分群和分子育种应用中基因型鉴定的SNP位点数越来越多,亟需系统地比较不同分群方法以便找到最合适的分群法和最可靠的分群功效评估指标。本研究比较了4个分群方... 随着高通量测序技术的不断进步带来的SNP标记成本的持续下降,可用于种质资源分群和分子育种应用中基因型鉴定的SNP位点数越来越多,亟需系统地比较不同分群方法以便找到最合适的分群法和最可靠的分群功效评估指标。本研究比较了4个分群方法(包括目前常用的邻接算法(NJ法)、SNPhylo法、ADMIXTURE+SNPs和在ADMIXTURE+SNPs基础上开发的ADMIXTURE+TagSNPs分群法),以及4个分群功效评估指标(PCA散点图、群体遗传指标GD和PIC及贝叶斯统计指标BIC)在利用GBS简化基因组测序产生的525141个SNPs位点数据将490份玉米自交系划分成3个和6个亚群时的表现。结果表明:4个评估指标中的PCA散点图和BIC指标(BICBW,SBIC)探测亚群间变异的能力强,是评估不同分群方法分群功效的可靠指标,而GD和PIC探测亚群间变异的能力差,不适合用作分群功效的评估。结果还表明,4个分群法均为有效分群法,所以都可用于种质资源分群,但ADMIXTURE+TagSNPs分群法划分的亚群边界清晰,亚群间个体混杂少,相对群间变异度大,综合表现最好,而SNPhylo法的综合表现最差。考虑到ADMIXTURE+TagSNPs需要输入的SNP标记数显著少于其他3种分群法,因而实际应用中基因型鉴定的成本最低,所以建议在遗传资源研究和分子育种应用中首选该分群法。 展开更多
关键词 玉米 聚类分析 标签SNP 主成分分析 遗传多样性 多态信息 贝叶斯信息度
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Impact of correlated private signals on continuous-time insider trading
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作者 ZHOU Yonghui XIAO Kai 《运筹学学报(中英文)》 2024年第3期97-107,共11页
A model of continuous-time insider trading in which a risk-neutral in-sider possesses two imperfect correlated signals of a risky asset is studied.By conditional expectation theory and filtering theory,we first establ... A model of continuous-time insider trading in which a risk-neutral in-sider possesses two imperfect correlated signals of a risky asset is studied.By conditional expectation theory and filtering theory,we first establish three lemmas:normal corre-lation,equivalent pricing and equivalent profit,which can guarantee to turn our model into a model with insider knowing full information.Then we investigate the impact of the two correlated signals on the market equilibrium consisting of optimal insider trading strategy and semi-strong pricing rule.It shows that in the equilibrium,(1)the market depth is constant over time;(2)if the two noisy signals are not linerly correlated,then all private information of the insider is incorporated into prices in the end while the whole information on the asset value can not incorporated into prices in the end;(3)if the two noisy signals are linear correlated such that the insider can infer the whole information of the asset value,then our model turns into a model with insider knowing full information;(4)if the two noisy signals are the same then the total ex ant profit of the insider is increasing with the noise decreasing,while down to O as the noise going up to infinity;(5)if the two noisy signals are not linear correlated then with one noisy signal fixed,the total ex ante profit of the insider is single-peaked with a unique minimum with respect to the other noisy signal value,and furthermore as the noisy value going to O it gets its maximum,the profit in the case that the real value is observed. 展开更多
关键词 continuous-time insider trading risk neutral private correlated signals linear bayesian equilibrium market depth residual information
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