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川产建曲的质变因素与解决措施 被引量:3
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作者 李翠萍 《中国西部科技》 2005年第11A期8-8,10,共2页
本文阐述了有关市场流通的川产建曲的质量低下和疗效差等现状的原因,并针对问题的原因,提出了科学的、合理的解决措施。为建曲质量控制提供了实验方法和参考数据。
关键词 建曲 质变因素 解决措施
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The influence of intensity and properties of tectonic stress on the process of coalification 被引量:1
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作者 WANG Zhi-rong JIANG Bo CHEN Ling-xia 《Journal of Coal Science & Engineering(China)》 2012年第2期158-162,共5页
Through the research on stress metamorphism character of the II1 coal seam in Ludian gliding structure, the stress effecting factors of metamorphism and hydrocarbon generation process of tectonic coal were studied. It... Through the research on stress metamorphism character of the II1 coal seam in Ludian gliding structure, the stress effecting factors of metamorphism and hydrocarbon generation process of tectonic coal were studied. It is shown that different tectonic stress has different coal evolution effects. Compared with tensional stress, compressive stress, which has apparent anisotropic characteristics, has greater stimulative effect against the increase of coal metamorphic degree, the abscission of functional group and side chains of basic structural unit, and the formation of gas primarily composed of methane. 展开更多
关键词 tectonic stress gliding structure coal metamorphism and hydrocarbon generation process gas geological hazards
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Mass genetics study of rhodopsin point mutations in retinitis pigmentosa
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作者 张晓莉 阴正勤 +1 位作者 张雪 府伟灵 《Journal of Medical Colleges of PLA(China)》 CAS 2004年第5期297-301,共5页
Objective: To evaluate the incidence and pattern of rhodopsin (RHO) mutations in Chinese patients with retinitis pigmentosa (RP). Methods: Conformation sensitive gel electrophoresis (CSGE) and direct DNA sequencing we... Objective: To evaluate the incidence and pattern of rhodopsin (RHO) mutations in Chinese patients with retinitis pigmentosa (RP). Methods: Conformation sensitive gel electrophoresis (CSGE) and direct DNA sequencing were applied to detect point mutations that occurred in the five coding exons and splice sites of RHO gene in 98 index patients with RP. Results: Four patients of one ADRP family were found to have a missense mutation at codon 347, Pro347Leu. One late-onset RP patient and her daughter, without clinical expression at present, were discovered to have a novel frameshift mutation at codon 327, Pro327 (1-bp del) . Neither of the two mutations was found in 100 normal controls. Ala299Ser was found in one RP patient. Two control subjects also had Ala299Ser, suggesting its nonpathogenicity and just single nucleotide polymorphism (SNP). Conclusion: Two RP patients had rhodopsin mutations, thus the expected frequency of RHO mutations in RP is about 2.0% (95% confidence interval: 0.3%-4.4%). A highly conserved C-terminal sequence QVS(A) PA was altered due to Pro347Leu and thereby misdirecting rhodopsin to incorrect subcellular location. Loss of all phosphory-lation sites at the C-terminus and a highly conserved sequence QVS(A)PA may occur because of Pro327(1-bp del) . To elucidate the predominant biochemical defects in such mutant, transgenic mice and transfected culture cells carrying Pro327(1-bp del) would be of great value. 展开更多
关键词 retinitis pigmentosa RHODOPSIN MUTATION conformation sensitive gel electrophoresis SEQUENCING
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Doublecortin and CaM kinase-like-1 as an independent prognostic factor in patients with resected pancreatic carcinoma 被引量:3
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作者 Kohei Nishio Kenjiro Kimura +9 位作者 Ryosuke Amano Bunzo Nakata Sadaaki Yamazoe Go Ohira Kotaro Miura Naoki Kametani Hiroaki Tanaka Kazuya Muguruma Kosei Hirakawa Masaichi Ohira 《World Journal of Gastroenterology》 SCIE CAS 2017年第31期5764-5772,共9页
To elucidate the effect of expression of doublecortin and CaM kinase-like-1 (DCLK1) in patients with pancreatic ductal adenocarcinoma (PDAC). METHODSTumor specimens were obtained from 136 patients with pancreatic canc... To elucidate the effect of expression of doublecortin and CaM kinase-like-1 (DCLK1) in patients with pancreatic ductal adenocarcinoma (PDAC). METHODSTumor specimens were obtained from 136 patients with pancreatic cancer who had undergone resection without preoperative therapy between January 2000 and December 2013 at the Department of Surgical Oncology, Osaka City University. The resected specimens were analyzed for associations with clinicopathological data, including DCLK1 expression, epithelial mesenchymal transition (EMT) marker expression, and cancer stem cell (CSC) marker expression. Univariate and multivariate survival analyses were performed and we assessed the association between DCLK1 expression and clinicopathological factors, including the EMT marker and CSC marker. RESULTSIn total, 48.5% (66/136) of the pancreatic cancer samples were positive for DCLK1. Patients with DCLK1-positive tumors had significantly shorter survival times than those with DCLK1-negative tumors (median, 18.7 mo vs 49.5 mo, respectively; P < 0.0001). Positive DCLK1 expression correlated with histological grade (P = 0.0290), preoperative CA19-9 level (P = 0.0060), epithelial cell adhesion molecule (EpCAM) expression (P = 0.0235), and the triple-positive expression of CD44/CD24/EpCAM (P = 0.0139). On univariate survival analysis, five factors were significantly associated with worse overall survival: histological grade of G2 to G4 (P = 0.0091), high preoperative serum SPan-1 level (P = 0.0034), R1/2 (P < 0.0001), positive expression of DCLK1 (P < 0.0001) or CD44 (P = 0.0245). On multivariate survival analysis, R1/2 [odds ratio (OR) = 2.019, 95% confidence interval (CI): 1.380-2.933; P = 0.0004] and positive DCLK1 expression (OR = 1.848, 95%CI: 1.2854-2.661; P = 0.0009) were independent prognostic factors. CONCLUSIONDCLK1 expression was found to be an independent prognostic factor and it may play a crucial prognostic role by promoting acquisition of stemness. 展开更多
关键词 Doublecortin and CaM kinase-like-1 Pancreatic cancer Epithelial mesenchymal transition Cancer stem cell Prognostic factor
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Identifying Key Environmental Factors Influencing Spatial Variation of Water Quality in Upper Shitoukoumen Reservoir Basin in Jilin Province,China
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作者 TANG Yanling ZHANG Guangxin +1 位作者 YANG Yuesuo GAO Yingzhi 《Chinese Geographical Science》 SCIE CSCD 2009年第4期365-374,共10页
Based on the observed data in monitored drainage areas and GIS spatial analysis tools,watershed basic database of Shitoukoumen Reservoir Basin was built.The multivariate analysis and redundancy analysis(RDA) were used... Based on the observed data in monitored drainage areas and GIS spatial analysis tools,watershed basic database of Shitoukoumen Reservoir Basin was built.The multivariate analysis and redundancy analysis(RDA) were used to analyze the spatial and temporal variations of water quality,identify the key environmental factors and their patterns influencing the spatial variation of water quality,and determine the main types and forms of the non-point source(NPS) pollutant export controlled by the key environmental factors.The results show that different patterns of environmental factors lead to great changes in water quality at spatial and seasonal scales.All selected environmental factors explain 64.5% and 68.2% of the spatial variation of water quality over dry season and rainy season,respectively,which shows clear seasonal difference.Over dry season,residential land is the most important environmental factor,which possesses 35.4% of the spatial variation,and drainage area is the second key environmental factor,which possesses 17.0% of spatial variation in the total variance.Over rainy season,slope length and drainage area are the key environmental factors,which possess 29.3% of the spatial variation together.Residential land influences nitrogen export by changing NH4+-N and particulate organic nitrogen(PON) discharge over dry season,and drainage area controls phosphorus export by regulating dissolved phosphorus(DP) drainage over dry season and phosphorus associated particulate(PAP) loss over rainy season,respectively.Although slope length is an important environmental factor,it does not influence NPS pollutant export.It is interesting that soil organic matter,as a minor environmental factor,highly determines phosphorus and nitrogen export by enhancing the DP,PAP and PON loss. 展开更多
关键词 non-point source pollution key environmental factor redundancy analysis Shitoukoumen Reservoir
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基于感知模式纹理的人脸识别
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作者 王小冬 黄陈蓉 《南京工程学院学报(自然科学版)》 2016年第4期10-15,共6页
稀疏表示分类法和局部二值模式是目前广泛运用的人脸表示方法.虽然稀疏表示分类法通过重构算法能很好的稀疏表示人脸,但在人脸的局部特征表示上不够理想.局部二值模式是基于局部纹理特征表示人脸,其提取的局部纹理简单、不连续、不光滑... 稀疏表示分类法和局部二值模式是目前广泛运用的人脸表示方法.虽然稀疏表示分类法通过重构算法能很好的稀疏表示人脸,但在人脸的局部特征表示上不够理想.局部二值模式是基于局部纹理特征表示人脸,其提取的局部纹理简单、不连续、不光滑,造成纹理损失严重.提出局部纹理特征的感知模式纹理的概念,克服了稀疏表示分类法在局部特征表现不佳的缺点,同时又比局部二值模式纹理光滑、鲁棒.利用感知模式纹理特征在Yale和ORL数据库取得了较好的识别效果. 展开更多
关键词 稀疏表示 局部二值模式 感知模式纹理 冗余字典
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Multivariate Analysis in the Climate Change Studies and Water Quality of Lake Patzcuaro (Mexico)
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《Journal of Mathematics and System Science》 2012年第8期469-481,共13页
In this study, the authors carried out the systemic analysis of water quality of Lake Patzcuaro in relationship with the climate change during a period of 85 years. The statistical comparison (medians, "t" Student ... In this study, the authors carried out the systemic analysis of water quality of Lake Patzcuaro in relationship with the climate change during a period of 85 years. The statistical comparison (medians, "t" Student test, regressions and correlations) for the precipitation, evaporation, observed temperature, minimum and maximum for the periods 1969-1988 (pre-impact) and 1988-2007 (post-impact) was realized. The "t" Student test for water quality during the period of 1981-2011, as well as, the regression analysis and multiple linear correlation of water quality from 2006 to 2011 were applied in joint way of the Cluster and Principal Component to observe the effects of climate change on water quality and vulnerability of Lake Patzcuaro. The comparative analysis of the meteorological data for 1921-1960 and 1973-2007 by the KOppen classification showed a climate change. The comparative Box Plots diagrams for 1973-1989 and 1989-2007, as well as, the "t" Student test, linear regression and correlation indicated significant changes in time for precipitation, evaporation, observed temperature, minimum and maximum (P ≤ 0.05). The correlation and regression analysis indicated significant positive trends for turbidity, conductivity, total phosphorus, aluminum, oils and grease, in contrast with Secchi disk depth, transparency, Redox potential and dissolved oxygen concentration. The "t" Student test showed significant differences between 1981 and 2011 for transparency, hardness, alkalinity, conductivity, nitrite, and phosphate. Cluster and Principal Components of the physicochemical and biological of 2006-2011 confirmed the vulnerability of the system by human growth and climate change influence. 展开更多
关键词 Climatic change LIMNOLOGY statistical analysis.
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浅议碳酸饮料变质的原因及解决办法
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作者 韩金凯 《辽宁食品与发酵》 1996年第1期29-31,共3页
本文探讨了有关碳酸饮料变质的原因,指出微生物、物理、化学及生物化学等方面的作用对碳酸饮料质量的影响,并提供预防碳酸饮料变质的措施。
关键词 饮料 碳酸饮料 质变因素 防止
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Periodically poled lithium niobate whispering gallery mode microcavities on a chip 被引量:9
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作者 ZhenZhong Hao Li Zhang +7 位作者 Ang Gao WenBo Mao XiaoDan Lyu XiaoMei Gao Fang Bo Feng Gao GuoQuan Zhang JingJun Xu 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS CSCD 2018年第11期36-40,共5页
In this study, we investigate the fabrication of periodically poled lithium niobate(PPLN) microdisk cavities on a chip. These resonators are fabricated from a PPLN film with a 16 μm poling period on insulator using c... In this study, we investigate the fabrication of periodically poled lithium niobate(PPLN) microdisk cavities on a chip. These resonators are fabricated from a PPLN film with a 16 μm poling period on insulator using conventional microfabrication techniques.The quality factor of the PPLN microdisk resonators with a 40-μm radius and a 700-nm thickness is 6.7×10~5. Second harmonic generation(SHG) with an efficiency of 2.2×10^(-6) mW(-1) is demonstrated in the fabricated PPLN microdisks. The nonlinear conversion efficiency could be considerably enhanced by optimizing the period and pattern of the poled structure and by improving the cavity quality factors. 展开更多
关键词 whispering gallery mode periodically poled lithium niobate MICROCAVITIES second harmonic generation
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