To improve the surface properties,lining of magnesium alloys with hard powders by shot peening was carried out in order. The hard powders were tried to bond to the workpiece surface due to the collision of many shots....To improve the surface properties,lining of magnesium alloys with hard powders by shot peening was carried out in order. The hard powders were tried to bond to the workpiece surface due to the collision of many shots.In order to fix the hard powders to the surface of the workpiece,the powders were set on an uneven surface.To easily facilitate fixing of powders,lining of the workpiece with the powder sandwiched between two aluminum foil sheets was also attempted.In this experiment,a centrifugal shot peening machine with an electrical heater was employed.The workpieces were magnesium alloys AZ31B and AZ91D,and the hard powders were commercial cemented carbide,alumina,and zirconia.The joinability of hard powders near the lined surface was observed by a optical microscope.The wear resistance was also evaluated by a wear test.The hard powders were successfully bonded to the surface of workpieces by the shot lining process.The results show that the present method is effective in wear resistance of the magnesium alloys.展开更多
Objective： The aim of our study was to observe the efficacy and toxicity of 50 cases of advanced non-small cell lung cancer （NSCLC） patients treated by pemetrexed. Methods： Fifty patients, including 29 females and...Objective： The aim of our study was to observe the efficacy and toxicity of 50 cases of advanced non-small cell lung cancer （NSCLC） patients treated by pemetrexed. Methods： Fifty patients, including 29 females and 21 males, with a median age 62 years （35–82 years）, 13 of whom were treated with pemetrexed only and the left 37 cases were treated with pemetrexed combined with platinum in the Department of Oncology, Renmin Hospital of Wuhan University from June 2006 to March 2009. Single agent regimen： patients received pemetrexed 500 mg/m2 on day 1 with every 21 days. Combination regimen： patients received pemetrexed 500 mg/m2 on day 1 and carboplatin 300 mg/m2 on day 1 or cisplatin 35 mg/m2 on day 1 to day 3 or nedaplatin 80 mg/m2 on day 1 by intravenous infusion with 21 days as one cycle. RECIST 1.0 standard was used to evaluate the clinical efficiency, and the WHO toxicity standard was used to evaluate toxic reaction, and the QOL was used to evaluate the quality of life. Results： All patients were given 162 cycles （at least 2 cycles, at most 6 cycles） and the response rate of all the patients were evaluated. There were 2 complete remission （CR）, 7 partial remission （PR）, 22 stable disease （SD） and 19 progressive disease （PD） in the group, the overall response rate was （RR） was 18.0% and disease control rate （DCR） 62.0%. The quality of life improvement rate reaches 58.0%. The major toxic reaction included neutropenia, thrombocytopenia, hypemia, nausea, and vomiting. Most of the severity of these effects was grade I–II and well tolerated. Conclusion： Chemotherapy with pemetrexed or pemetrexed combined with platinum in the treatment of advanced non-small cell lung cancer is effective, safe and well-tolerable, which can improve quality of life of the patient.展开更多
Soil water-retention characteristics at measurement scales are generally different from those at application scales, and there is scale disparity between them and soil physical properties. The relationships between tw...Soil water-retention characteristics at measurement scales are generally different from those at application scales, and there is scale disparity between them and soil physical properties. The relationships between two water-retention parameters, the scaling parameter related to the inverse of the air-entry pressure （avG, cm- 1） and the curve shape factor related to soil pore-size distribution （n） of the van Genuchten water-retention equation, and soil texture （sand, silt, and clay contents） were examined at multiple scales. One hundred twenty-eight undisturbed soil samples were collected from a 640-m transect located in Fuxin, China. Soil water-retention curves were measured and the van Genuchten parameters were obtained by curve fitting. The relationships between the two parameters and soil texture at the observed scale and at multiple scales were evaluated using Pearson correlation and joint multifractal analyses, respectively. The results of Pearson correlation analysis showed that the parameter c^vG was significantly correlated with sand, silt, and clay contents at the observed scale. Joint multifractal analyses, however, indicated that the parameter ~vG was not correlated with silt and sand contents at multiple scales. The parameter n was positively correlated with clay content at multiple scales. Sand content was significantly correlated with the parameter n at the observed scale but not at multiple scales. Clay contents were strongly correlated to both water-retention parameters because clay content was relatively low in the soil studied, indicating that water retention was dominated by clay content in the field of this study at all scales. These suggested that multiple-scale analyses were necessary to fully grasp the spatial variability of soil water-retention characteristics.展开更多
Experimentally observed ground state band based on the 1/2-[521] Nilsson state and the first exited band based on the 7/2-[514] Nilsson state of the odd-Z nucleus 255Lr are studied by the cranked shell model （CSM） w...Experimentally observed ground state band based on the 1/2-[521] Nilsson state and the first exited band based on the 7/2-[514] Nilsson state of the odd-Z nucleus 255Lr are studied by the cranked shell model （CSM） with the paring correlations treated by the particle-number-conserving （PNC） method. This is the first time the detailed theoretical investigations are performed on these rotational bands. Both experimental kinematic and dynamic moments of inertia （f^（1） and ,f^（2） versus rotational frequency are reproduced quite well by the PNC-CSM calculations. By comparing the theoretical kinematic moment of inertia f（1） with the experimental ones extracted from different spin assignments, the spin 17/2- →13/2- is assigned to the lowest-lying 196.6（5） keV transition of the 1/2- [521 ] band, and 15/2→11/2- to the 189（1） keV transition of the 7/2- [514] band, respectively. The proton N = 7 major shell is included in the calculations. The intruder of the high-j low→lj15/2 （1/2-[770]） orbital at the high spin leads to band-crossings at hω = 0.20 （hω~=0.25） MeV for the 7/2-[514]ω= -1/2 （ω= ＋1/2） band, and at hω=0.175 MeV for the 1/2- [521 ] ω= - 1/2 band, respectively. Further investigations show that the band-crossing frequencies are quadrupole deformation dependent.展开更多
文摘To improve the surface properties,lining of magnesium alloys with hard powders by shot peening was carried out in order. The hard powders were tried to bond to the workpiece surface due to the collision of many shots.In order to fix the hard powders to the surface of the workpiece,the powders were set on an uneven surface.To easily facilitate fixing of powders,lining of the workpiece with the powder sandwiched between two aluminum foil sheets was also attempted.In this experiment,a centrifugal shot peening machine with an electrical heater was employed.The workpieces were magnesium alloys AZ31B and AZ91D,and the hard powders were commercial cemented carbide,alumina,and zirconia.The joinability of hard powders near the lined surface was observed by a optical microscope.The wear resistance was also evaluated by a wear test.The hard powders were successfully bonded to the surface of workpieces by the shot lining process.The results show that the present method is effective in wear resistance of the magnesium alloys.
文摘Objective： The aim of our study was to observe the efficacy and toxicity of 50 cases of advanced non-small cell lung cancer （NSCLC） patients treated by pemetrexed. Methods： Fifty patients, including 29 females and 21 males, with a median age 62 years （35–82 years）, 13 of whom were treated with pemetrexed only and the left 37 cases were treated with pemetrexed combined with platinum in the Department of Oncology, Renmin Hospital of Wuhan University from June 2006 to March 2009. Single agent regimen： patients received pemetrexed 500 mg/m2 on day 1 with every 21 days. Combination regimen： patients received pemetrexed 500 mg/m2 on day 1 and carboplatin 300 mg/m2 on day 1 or cisplatin 35 mg/m2 on day 1 to day 3 or nedaplatin 80 mg/m2 on day 1 by intravenous infusion with 21 days as one cycle. RECIST 1.0 standard was used to evaluate the clinical efficiency, and the WHO toxicity standard was used to evaluate toxic reaction, and the QOL was used to evaluate the quality of life. Results： All patients were given 162 cycles （at least 2 cycles, at most 6 cycles） and the response rate of all the patients were evaluated. There were 2 complete remission （CR）, 7 partial remission （PR）, 22 stable disease （SD） and 19 progressive disease （PD） in the group, the overall response rate was （RR） was 18.0% and disease control rate （DCR） 62.0%. The quality of life improvement rate reaches 58.0%. The major toxic reaction included neutropenia, thrombocytopenia, hypemia, nausea, and vomiting. Most of the severity of these effects was grade I–II and well tolerated. Conclusion： Chemotherapy with pemetrexed or pemetrexed combined with platinum in the treatment of advanced non-small cell lung cancer is effective, safe and well-tolerable, which can improve quality of life of the patient.
基金Supported by the National Key Technology R&D Program in the 11th Five-Year Plan of China (Nos.2008BADA4B03 and 2009BADB3B07)
文摘Soil water-retention characteristics at measurement scales are generally different from those at application scales, and there is scale disparity between them and soil physical properties. The relationships between two water-retention parameters, the scaling parameter related to the inverse of the air-entry pressure （avG, cm- 1） and the curve shape factor related to soil pore-size distribution （n） of the van Genuchten water-retention equation, and soil texture （sand, silt, and clay contents） were examined at multiple scales. One hundred twenty-eight undisturbed soil samples were collected from a 640-m transect located in Fuxin, China. Soil water-retention curves were measured and the van Genuchten parameters were obtained by curve fitting. The relationships between the two parameters and soil texture at the observed scale and at multiple scales were evaluated using Pearson correlation and joint multifractal analyses, respectively. The results of Pearson correlation analysis showed that the parameter c^vG was significantly correlated with sand, silt, and clay contents at the observed scale. Joint multifractal analyses, however, indicated that the parameter ~vG was not correlated with silt and sand contents at multiple scales. The parameter n was positively correlated with clay content at multiple scales. Sand content was significantly correlated with the parameter n at the observed scale but not at multiple scales. Clay contents were strongly correlated to both water-retention parameters because clay content was relatively low in the soil studied, indicating that water retention was dominated by clay content in the field of this study at all scales. These suggested that multiple-scale analyses were necessary to fully grasp the spatial variability of soil water-retention characteristics.
基金supported by the National Natural Science Foundation of China(Grant Nos.11275098 and 11275067)the Priority Academic Program Development of Jiangsu Higher Education Institutions
文摘Experimentally observed ground state band based on the 1/2-[521] Nilsson state and the first exited band based on the 7/2-[514] Nilsson state of the odd-Z nucleus 255Lr are studied by the cranked shell model （CSM） with the paring correlations treated by the particle-number-conserving （PNC） method. This is the first time the detailed theoretical investigations are performed on these rotational bands. Both experimental kinematic and dynamic moments of inertia （f^（1） and ,f^（2） versus rotational frequency are reproduced quite well by the PNC-CSM calculations. By comparing the theoretical kinematic moment of inertia f（1） with the experimental ones extracted from different spin assignments, the spin 17/2- →13/2- is assigned to the lowest-lying 196.6（5） keV transition of the 1/2- [521 ] band, and 15/2→11/2- to the 189（1） keV transition of the 7/2- [514] band, respectively. The proton N = 7 major shell is included in the calculations. The intruder of the high-j low→lj15/2 （1/2-[770]） orbital at the high spin leads to band-crossings at hω = 0.20 （hω~=0.25） MeV for the 7/2-[514]ω= -1/2 （ω= ＋1/2） band, and at hω=0.175 MeV for the 1/2- [521 ] ω= - 1/2 band, respectively. Further investigations show that the band-crossing frequencies are quadrupole deformation dependent.
