The origin, classification, utilization and evaluation of germplasm resources, and breeding methods were introduced. The researches of biotic or/and abiotic stress, exploration of genomics and proteomics in common bea...The origin, classification, utilization and evaluation of germplasm resources, and breeding methods were introduced. The researches of biotic or/and abiotic stress, exploration of genomics and proteomics in common bean in recent years were reviewed in this paper, in order to provide theoretical reference for utilization and innovation of germplasm resources in common bean.展开更多
In this study, peaches of cv. ＇Sui Yuan＇ with different maturities were treated with 0.05 mM sodium nitroprusside （SNP）, a nitric oxide donor, for 5 min, at 28℃, and then stored at 0-1.5℃ for 30 days. Untreated ...In this study, peaches of cv. ＇Sui Yuan＇ with different maturities were treated with 0.05 mM sodium nitroprusside （SNP）, a nitric oxide donor, for 5 min, at 28℃, and then stored at 0-1.5℃ for 30 days. Untreated fruits stored under the same conditions were used as control fruits in the experiment. The browning level, activities of polyphenol oxidase （PPO）, peroxydase （POD） and superoxide dismutase （SOD）, and quality parameters （firmness, titratable acid, total soluble solids and total sugar） were analyzed. The results showed that the firmness of SNP-treated fruit at different stage of maturity were higher than that of the control fruit after storage for 30 days. However, no significant effect was found on total soluble solid content. The titratable acid content of low maturity fruit was higher in SNP-treated one than that of the control, but the titratable acid content of high maturity fruit treated by SNP was lower than that of the control on 10th and 30th day. In addition, the combination of SNP treatment and high maturity resulted in higher activities of SOD, lower activity of PPO and POD, lower browning level. Therefore, the combination of high maturity and SNP treatment might be a useful method to well maintain honey peach fruit quality during cold storage.展开更多
Aim To establish a new and sensitive HPLC-MS method for the determination ofzolmitriptan in human plasma and study the pharmacokinetics of zolmitriptan in healthy volunteers.Methods A single oral dose of 5 mg of zolmi...Aim To establish a new and sensitive HPLC-MS method for the determination ofzolmitriptan in human plasma and study the pharmacokinetics of zolmitriptan in healthy volunteers.Methods A single oral dose of 5 mg of zolmitriptan tablet was given to 20 healthy male volunteers.After dosing, blood samples were collected for a period of 24 h, and zolmitriptan concentration inplasma was analyzed by HPLC-MS. Results The plasma concentration-time course fitted well atwo-compartment open model with a lag time, giving the following pharmacokinetic parameters: T_(max)1.60 ± 0.24 h, C_(max) 9.73 ± 1.43 ng·mL^(-1). T_(1/2α)1.72±0.46 h, T_(1/2β) 4.52 + 0.97 h,and AUC_(0-t) 55.59 ± 5.12 ng·mL^(-1)·h. Conclusion The improved analytical method forzolmitriptan is rapid, sensitive and suitable for application to pharmacokinetic studies and routinedetermination of numerous samples.展开更多
The main purpose of this study was to investigate the protective actions of captopril and cicaprost on changes of membrane fluidity of cultured neonatal rat myocardial cells exposed to anoxia and sugar deprivation.Lip...The main purpose of this study was to investigate the protective actions of captopril and cicaprost on changes of membrane fluidity of cultured neonatal rat myocardial cells exposed to anoxia and sugar deprivation.Lipid peroxidation level estimated by determining the thiobarbituric acid reactive substance(TBARS)content and lactate dehydrogenase(LDH)released in culture medium was also observed in order to examine other membrane-related changes due to anoxia.Membrane fluidity was monitored by measuring changes in the steady state fluorescence anisotropy(r_s)by fluorescence spectroscopy.The r_s value,TBARS level and LDH release were significantly increased after 3 h anoxia.Captopril(180 μmol/L),cicaprost(30 nmol/L)and indomethacin(1μmol/L)did not alter r_s, TBARS level and LDH activity of normal cultured neonatal rat myocardial cells.However,both captopril and cicaprost significantly prevented the increases of r_s,TBARS content and LDH release in those cells exposed to anoxia and sugar deprivation.lndomethacin abolished the actions of captopril on TBARS production and LDH release,but maintained its membrane fluidity protection.These results indicate that captopril and cicaprost protect membrane fluidity and lipid peroxidation changes in anoxia- injured myocardial cells.The action mechanism of captopril may be due,in part,to stimulation of prostacyclin synthesis and/or release.展开更多
Doppler centroid frequency is an essential parameter in the imaging processing of the Scanning mode Synthetic Aperture Radar (ScanSAR). Inaccurate Doppler centroid frequency will result in ghost images in imaging resu...Doppler centroid frequency is an essential parameter in the imaging processing of the Scanning mode Synthetic Aperture Radar (ScanSAR). Inaccurate Doppler centroid frequency will result in ghost images in imaging result. In this letter, the principle and algorithms of Doppler centroid frequency estimation are introduced. Then the echo data of ScanSAR system is analyzed. Based on the algorithms of energy balancing and correlation Doppler estimator in the estimation of Doppler centroid frequency in strip mode SAR, an improved method for Doppler centroid frequency estimation in ScanSAR is proposed. The method has improved the accuracy of Doppler centroid frequency estimation in ScanSAR by zero padding between burst data. Finally, the proposed method is validated with the processing of ENVIronment SATellite Advanced Synthetic Aperture Radar (ENVISAT ASAR) wide swath raw data.展开更多
In this paper we study the local measure of approximation of a class of special mathematical expectation operators to Lipschitz class of functions by probabilistic method. The some well known operators (e. g., the Ber...In this paper we study the local measure of approximation of a class of special mathematical expectation operators to Lipschitz class of functions by probabilistic method. The some well known operators (e. g., the Bernstein, Bascakov and Szasz-Mirakjan operators etc) are special cases of a class of the mathematical expetation operators.展开更多
The constraint on the total energy in a given spatial region is given from holography by the mass of a black hole that just fits in that region, which leads to an UV/IR relation： the maximal energy density in that re...The constraint on the total energy in a given spatial region is given from holography by the mass of a black hole that just fits in that region, which leads to an UV/IR relation： the maximal energy density in that region is proportional to Mp^2/L^2, where Mp is the Planck mass and L is the spatial scale of that region under consideration. Assuming the maximal black hole in the universe is formed through gravitational collapse of perturbations in the universe, then the ＂Jeans＂ scale of the perturbations gives a causal connection scale RCC. For gravitational perturbations, RCC^-2= Max （H＋ 2H^2, -H） for a fiat universe. We study the cosmological dynamics of the corresponding vacuum energy density by choosing the causal connection scale as the IR cutoff in the UV/IR relation, in the cases of the vacuum energy density as an independently conserved energy component and an effective dynamical cosmological constant, respectively. It turns out that only the case with the choice RCC^-2 = H＋ 2H^2, could be consistent with the current cosmological observations when the vacuum density appears as an independently conserved energy component. In this case, the model is called holographic Ricci scalar dark energy model in the literature.展开更多
Two trace impurities in the bulk drug lisinopril were detected by means of high-performance liquid chromatography coupled with mass spectrometry （HPLC/MS） with a simple and sensitive method suitable for HPLC/MSn ana...Two trace impurities in the bulk drug lisinopril were detected by means of high-performance liquid chromatography coupled with mass spectrometry （HPLC/MS） with a simple and sensitive method suitable for HPLC/MSn analysis. The fragmentation behavior of lisinopfil and the impurities was investigated, and two unknown impurities were elucidated as 2-（6-amino- l-（l-carboxyethylamino）- l-oxohexan-2-ylamino）-4-phenylbutanoic acid and 6-amino-2-（l-carboxy-3-phenylpropylamino）-hexanoic acid on the basis of the multi-stage mass spectrometry and exact mass evidence, The proposed structures of the two unknown impurities were further confirmed by nuclear magnetic resonance （NMR） experiments after preparative isolation.展开更多
Blazars are subclass of AGN （active galactic nuclei） with relativistic jet that is pointing in the general direction of the earth. The energy flux in the jet is about （10^44-10^47） erg/s. The γ-rays in the energy...Blazars are subclass of AGN （active galactic nuclei） with relativistic jet that is pointing in the general direction of the earth. The energy flux in the jet is about （10^44-10^47） erg/s. The γ-rays in the energy range 10 GeV-10 TeV emanating from blazar are examined and their effect on the IGM （intergalactic medium） is studied. The γ-ray emission is considered as due to inverse Compton scattering of relativistic electrons. There appears to be a gamma ray flux from blazar above 10 GeV having a line intensity of 1.5 × 10^-4 cm^-2 s^-1 sr^-1. The IGM is measured to large distances and it is found to be clumpy. It is found that at higher redshifl the density of IGM increases. The cosmological density parameter measured is found to lie within the suggested limit of 0.03 at redshift z = 3 for background intensity of radiation 10^-24 W·m^-2·Hz^-1·sr^-1. The iso-ΩIGM curve shows a kink in its profile which might be significant at the particular value of z equal to 2. Some more detailed studies are required for understanding the distribution of intergalactic medium at the unstable point at z = 2 as shown in inverse Compton radiation.展开更多
A transverse Ising spin system, in the presence of time-dependent longitudinal field, is studied by the effective-field theory （EFT）. The effective-field equations of motion of the average magnetization are given fo...A transverse Ising spin system, in the presence of time-dependent longitudinal field, is studied by the effective-field theory （EFT）. The effective-field equations of motion of the average magnetization are given for the simple cubic lattice （Z ---- 6） and the honeycomb lattice （Z = 3）. The Liapunov exponent A is calculated for discussing the stability of the magnetization and it is used to determine the phase boundary. The dynamic phase transition diagrams in ho/ZJ - F/ZJ plane and in ho/ZJ - T/ZJ plane have been drawn, and there is no dynamical tricritical point on the dynamic phase transition boundary. The effect of the thermal fluctuations upon the dynamic phase boundary has been discussed.展开更多
We estimate the correction of relativistic center-of-mass vector on electric polarizability of an equal-mass quark-antiquark system numerically. Effect on the system confined by different interactive potentials is ana...We estimate the correction of relativistic center-of-mass vector on electric polarizability of an equal-mass quark-antiquark system numerically. Effect on the system confined by different interactive potentials is analysed. A great improvement for the electric polarizability of pion meson is obtained.展开更多
The possibility of stable or quasi-stable Planck mass black hole remnants as solution to the black hole information paradox is commonly believed phenomenologically unacceptable. Since we need a black hole remnant for ...The possibility of stable or quasi-stable Planck mass black hole remnants as solution to the black hole information paradox is commonly believed phenomenologically unacceptable. Since we need a black hole remnant for every possible initial state, the number of remnants is expected to be infinite and that would lead to remnant pair production in any physical process with a total available energy roughly exceeding the Planck mass. In this note I point out that a positive cosmological constant of the Universe would naturally lead to an upper bound on the number of possible remnants.展开更多
[Objective] The aim was to provide certain theoretical basis for the protection of broccoli. [Method] Exogenous sodium nitroprusside was used to in the experiment. Under the condition of 20 ℃ and RH 95%, the optimal ...[Objective] The aim was to provide certain theoretical basis for the protection of broccoli. [Method] Exogenous sodium nitroprusside was used to in the experiment. Under the condition of 20 ℃ and RH 95%, the optimal SNP concentration of broccoli was determined. [Result] The exogenous SNP could effectively maintain the quality of broccoli, inhabited the yellowing of broccoli and the increasing of cell membrane permeability, and maintain the soluble solids content, decreased the degradation rate of chlorophyll and delayed the loss of VC. [Conclusion] Exogenous sodium nitroprusside can effectively maintain the quality of broccoli to keep it fresh.展开更多
基金Supported by Postdoctor Initial Funding Project from Northeast China Agricultural Innovation Center(2013-2015)Fund for Overseas Students from the Personnel Department of Jilin Province(3140101)~~
文摘The origin, classification, utilization and evaluation of germplasm resources, and breeding methods were introduced. The researches of biotic or/and abiotic stress, exploration of genomics and proteomics in common bean in recent years were reviewed in this paper, in order to provide theoretical reference for utilization and innovation of germplasm resources in common bean.
基金Supported by the Nationa Science Foundation (NSF) Centers of Research Excellence in Science ad Technolog (NSF CREST, HRD- 0734850CBET MRI-0821370) at the Texas A&M University-IKngsville. The Robert C Welch (AC0006) Departmental Grant。
基金supported by National Key Technology R&D Program in the 11~(th) Five year Plan of China (2006BAD22B04)
文摘In this study, peaches of cv. ＇Sui Yuan＇ with different maturities were treated with 0.05 mM sodium nitroprusside （SNP）, a nitric oxide donor, for 5 min, at 28℃, and then stored at 0-1.5℃ for 30 days. Untreated fruits stored under the same conditions were used as control fruits in the experiment. The browning level, activities of polyphenol oxidase （PPO）, peroxydase （POD） and superoxide dismutase （SOD）, and quality parameters （firmness, titratable acid, total soluble solids and total sugar） were analyzed. The results showed that the firmness of SNP-treated fruit at different stage of maturity were higher than that of the control fruit after storage for 30 days. However, no significant effect was found on total soluble solid content. The titratable acid content of low maturity fruit was higher in SNP-treated one than that of the control, but the titratable acid content of high maturity fruit treated by SNP was lower than that of the control on 10th and 30th day. In addition, the combination of SNP treatment and high maturity resulted in higher activities of SOD, lower activity of PPO and POD, lower browning level. Therefore, the combination of high maturity and SNP treatment might be a useful method to well maintain honey peach fruit quality during cold storage.
文摘Aim To establish a new and sensitive HPLC-MS method for the determination ofzolmitriptan in human plasma and study the pharmacokinetics of zolmitriptan in healthy volunteers.Methods A single oral dose of 5 mg of zolmitriptan tablet was given to 20 healthy male volunteers.After dosing, blood samples were collected for a period of 24 h, and zolmitriptan concentration inplasma was analyzed by HPLC-MS. Results The plasma concentration-time course fitted well atwo-compartment open model with a lag time, giving the following pharmacokinetic parameters: T_(max)1.60 ± 0.24 h, C_(max) 9.73 ± 1.43 ng·mL^(-1). T_(1/2α)1.72±0.46 h, T_(1/2β) 4.52 + 0.97 h,and AUC_(0-t) 55.59 ± 5.12 ng·mL^(-1)·h. Conclusion The improved analytical method forzolmitriptan is rapid, sensitive and suitable for application to pharmacokinetic studies and routinedetermination of numerous samples.
基金Supported by a grant for young researcher from Ministry of Public Health of P.R.C.
文摘The main purpose of this study was to investigate the protective actions of captopril and cicaprost on changes of membrane fluidity of cultured neonatal rat myocardial cells exposed to anoxia and sugar deprivation.Lipid peroxidation level estimated by determining the thiobarbituric acid reactive substance(TBARS)content and lactate dehydrogenase(LDH)released in culture medium was also observed in order to examine other membrane-related changes due to anoxia.Membrane fluidity was monitored by measuring changes in the steady state fluorescence anisotropy(r_s)by fluorescence spectroscopy.The r_s value,TBARS level and LDH release were significantly increased after 3 h anoxia.Captopril(180 μmol/L),cicaprost(30 nmol/L)and indomethacin(1μmol/L)did not alter r_s, TBARS level and LDH activity of normal cultured neonatal rat myocardial cells.However,both captopril and cicaprost significantly prevented the increases of r_s,TBARS content and LDH release in those cells exposed to anoxia and sugar deprivation.lndomethacin abolished the actions of captopril on TBARS production and LDH release,but maintained its membrane fluidity protection.These results indicate that captopril and cicaprost protect membrane fluidity and lipid peroxidation changes in anoxia- injured myocardial cells.The action mechanism of captopril may be due,in part,to stimulation of prostacyclin synthesis and/or release.
文摘Doppler centroid frequency is an essential parameter in the imaging processing of the Scanning mode Synthetic Aperture Radar (ScanSAR). Inaccurate Doppler centroid frequency will result in ghost images in imaging result. In this letter, the principle and algorithms of Doppler centroid frequency estimation are introduced. Then the echo data of ScanSAR system is analyzed. Based on the algorithms of energy balancing and correlation Doppler estimator in the estimation of Doppler centroid frequency in strip mode SAR, an improved method for Doppler centroid frequency estimation in ScanSAR is proposed. The method has improved the accuracy of Doppler centroid frequency estimation in ScanSAR by zero padding between burst data. Finally, the proposed method is validated with the processing of ENVIronment SATellite Advanced Synthetic Aperture Radar (ENVISAT ASAR) wide swath raw data.
文摘In this paper we study the local measure of approximation of a class of special mathematical expectation operators to Lipschitz class of functions by probabilistic method. The some well known operators (e. g., the Bernstein, Bascakov and Szasz-Mirakjan operators etc) are special cases of a class of the mathematical expetation operators.
基金supported in part by the Chinese Academy of Sciences under Grant No.KJCX3-SYW-N2National Natural Science Foundation of China under Grant Nos.10821504 and 10525060
文摘The constraint on the total energy in a given spatial region is given from holography by the mass of a black hole that just fits in that region, which leads to an UV/IR relation： the maximal energy density in that region is proportional to Mp^2/L^2, where Mp is the Planck mass and L is the spatial scale of that region under consideration. Assuming the maximal black hole in the universe is formed through gravitational collapse of perturbations in the universe, then the ＂Jeans＂ scale of the perturbations gives a causal connection scale RCC. For gravitational perturbations, RCC^-2= Max （H＋ 2H^2, -H） for a fiat universe. We study the cosmological dynamics of the corresponding vacuum energy density by choosing the causal connection scale as the IR cutoff in the UV/IR relation, in the cases of the vacuum energy density as an independently conserved energy component and an effective dynamical cosmological constant, respectively. It turns out that only the case with the choice RCC^-2 = H＋ 2H^2, could be consistent with the current cosmological observations when the vacuum density appears as an independently conserved energy component. In this case, the model is called holographic Ricci scalar dark energy model in the literature.
基金Project (No. 20772109) supported by the National Natural ScienceFoundation of China
文摘Two trace impurities in the bulk drug lisinopril were detected by means of high-performance liquid chromatography coupled with mass spectrometry （HPLC/MS） with a simple and sensitive method suitable for HPLC/MSn analysis. The fragmentation behavior of lisinopfil and the impurities was investigated, and two unknown impurities were elucidated as 2-（6-amino- l-（l-carboxyethylamino）- l-oxohexan-2-ylamino）-4-phenylbutanoic acid and 6-amino-2-（l-carboxy-3-phenylpropylamino）-hexanoic acid on the basis of the multi-stage mass spectrometry and exact mass evidence, The proposed structures of the two unknown impurities were further confirmed by nuclear magnetic resonance （NMR） experiments after preparative isolation.
文摘Blazars are subclass of AGN （active galactic nuclei） with relativistic jet that is pointing in the general direction of the earth. The energy flux in the jet is about （10^44-10^47） erg/s. The γ-rays in the energy range 10 GeV-10 TeV emanating from blazar are examined and their effect on the IGM （intergalactic medium） is studied. The γ-ray emission is considered as due to inverse Compton scattering of relativistic electrons. There appears to be a gamma ray flux from blazar above 10 GeV having a line intensity of 1.5 × 10^-4 cm^-2 s^-1 sr^-1. The IGM is measured to large distances and it is found to be clumpy. It is found that at higher redshifl the density of IGM increases. The cosmological density parameter measured is found to lie within the suggested limit of 0.03 at redshift z = 3 for background intensity of radiation 10^-24 W·m^-2·Hz^-1·sr^-1. The iso-ΩIGM curve shows a kink in its profile which might be significant at the particular value of z equal to 2. Some more detailed studies are required for understanding the distribution of intergalactic medium at the unstable point at z = 2 as shown in inverse Compton radiation.
文摘A transverse Ising spin system, in the presence of time-dependent longitudinal field, is studied by the effective-field theory （EFT）. The effective-field equations of motion of the average magnetization are given for the simple cubic lattice （Z ---- 6） and the honeycomb lattice （Z = 3）. The Liapunov exponent A is calculated for discussing the stability of the magnetization and it is used to determine the phase boundary. The dynamic phase transition diagrams in ho/ZJ - F/ZJ plane and in ho/ZJ - T/ZJ plane have been drawn, and there is no dynamical tricritical point on the dynamic phase transition boundary. The effect of the thermal fluctuations upon the dynamic phase boundary has been discussed.
基金国家自然科学基金，the Institute of Theoretical Physics，中国科学院知识创新工程项目
文摘We estimate the correction of relativistic center-of-mass vector on electric polarizability of an equal-mass quark-antiquark system numerically. Effect on the system confined by different interactive potentials is analysed. A great improvement for the electric polarizability of pion meson is obtained.
基金supported in part by NSF under Grant No.PHY-0547794DOE under Grant No.DE-FG02-96ER41005
文摘The possibility of stable or quasi-stable Planck mass black hole remnants as solution to the black hole information paradox is commonly believed phenomenologically unacceptable. Since we need a black hole remnant for every possible initial state, the number of remnants is expected to be infinite and that would lead to remnant pair production in any physical process with a total available energy roughly exceeding the Planck mass. In this note I point out that a positive cosmological constant of the Universe would naturally lead to an upper bound on the number of possible remnants.
基金Supported by National Vegetable Industry System Construction
文摘[Objective] The aim was to provide certain theoretical basis for the protection of broccoli. [Method] Exogenous sodium nitroprusside was used to in the experiment. Under the condition of 20 ℃ and RH 95%, the optimal SNP concentration of broccoli was determined. [Result] The exogenous SNP could effectively maintain the quality of broccoli, inhabited the yellowing of broccoli and the increasing of cell membrane permeability, and maintain the soluble solids content, decreased the degradation rate of chlorophyll and delayed the loss of VC. [Conclusion] Exogenous sodium nitroprusside can effectively maintain the quality of broccoli to keep it fresh.
