The flow around airfoil NACA0012 enwrapped by the body-fitted grid is simulated by a coupled doubledistribution-function （DDF） lattice Boltzmann method （LBM） for the compressible Navier-Stokes equations. Firstly, ...The flow around airfoil NACA0012 enwrapped by the body-fitted grid is simulated by a coupled doubledistribution-function （DDF） lattice Boltzmann method （LBM） for the compressible Navier-Stokes equations. Firstly, the method is tested by simulating the low Reynolds number flow at Ma =0. 5,a=0. 0, Re=5 000. Then the simulation of flow around the airfoil is carried out at Ma：0. 5, 0. 85, 1.2; a=-0.05, 1.0, 0.0, respectively. And a better result is obtained by using a local refined grid. It reduces the error produced by the grid at Ma=0. 85. Though the inviscid boundary condition is used to avoid the problem of flow transition to turbulence at high Reynolds numbers, the pressure distribution obtained by the simulation agrees well with that of the experimental results. Thus, it proves the reliability of the method and shows its potential for the compressible flow simulation. The suecessful application to the flow around airfoil lays a foundation of the numerical simulation of turbulence.展开更多
Haloacetonitrile anions CH2XCN- （X=F, Cl） were studied by HF-SCF, Becke3-LYP, and MP2 methods together with the Dunning＇s basis set aug-cc-PVTZ. The vertical electron attachments to the neutral are endothermic. The...Haloacetonitrile anions CH2XCN- （X=F, Cl） were studied by HF-SCF, Becke3-LYP, and MP2 methods together with the Dunning＇s basis set aug-cc-PVTZ. The vertical electron attachments to the neutral are endothermic. The geometrically optimized CH2FCN^- is mainly a valence-bounded anion and CH2FCN→CH2CN＋F^- is a nonadiabatic dissociation. This theoretical study in good agreement with the experimental results shows that the Becke3-LYP method is reasonable in describing the electronic structures of anions and dissociative attachment dynamics, while significant differences between MP2 and Becke3-LYP results are shown for the dissociation potential curves of CH2ClCN→CH2CN＋Cl^-.展开更多
Based on the pipe transportation of paste-like backfilling system of a certain deep coal mine,its dynamics process was simulated and analyzed.A two-dimensional dynamic model of extraordinary deep and lone pipe was bui...Based on the pipe transportation of paste-like backfilling system of a certain deep coal mine,its dynamics process was simulated and analyzed.A two-dimensional dynamic model of extraordinary deep and lone pipe was built by GAMBIT,on the basis of which the simulation was done by implicit solver of FLUENT 2ddp.The results show that hydraulic loss of pipe transportation is less than the pressure produced by gravity,which means the backfilling material can flow by itself.When the inlet velocity is 3.2 m/s,the maximum velocity of 4.10 m/s is at the elbow and the maximum velocity in the horizontal pipe is 3.91 m/s,which can both meet the stability requirement.The results of the simulation are proved to be reliable by the residual monitor plotting of related parameter,so it can be concluded that the system of pipe transportation is safe.展开更多
The sinomenine hydrochloride （SH） patch, a topical drug delivery system, was prepared and characterized. The in vitro release was studied according to the paddle-over-disk method in the appendix of Chinese Pharmacop...The sinomenine hydrochloride （SH） patch, a topical drug delivery system, was prepared and characterized. The in vitro release was studied according to the paddle-over-disk method in the appendix of Chinese Pharmacopeia （appendix XD, 2005）. Stability of SH patch was evaluated at accelerated testing conditions （40 ℃, 75% RH）. Pharmacological and pharmacokinetics study were also performed. It was found that the release of SH from patches depended on pH value of the release medium. There were no significant differences between SH patches stored for 6 mon and those stored for 0 mon in the drug content, initial adhesion, lasting stickiness, peeling strength and in vitro release. SH patches exhibited better anti-inflammatory activity as well as analgesic efficacy. More importantly, primary pharmacokinetic parameters of SH patch, such as Cmax and AUC, were much lower than those of SH solution dosed orally. In conclusion, the patch might be a promising delivery system for SH, which bypassed the gastrointestinal tract and was a convenient, efficacious, safe and non-invasive delivery method.展开更多
Nanoindentation technique was adopted to investigate the chemomechanical properties change of hardened cement paste before and after carbonation.It was found that the mean elastic modulus and mean hardness obviously i...Nanoindentation technique was adopted to investigate the chemomechanical properties change of hardened cement paste before and after carbonation.It was found that the mean elastic modulus and mean hardness obviously increase after the carbonation reaction.Specifically,the probability of the elastic modulus showed a sharp reduction for the elastic modulus at the range of 7-34 and 83-160 GPa,in comparison of a large increase for the elastic modulus between 34-83 GPa.For the same reason,the probability of the hardness showed a large decrease when the hardness fell within 0.15-1.75 and 4.15-8.20 GPa and a dramatic increase for the hardness at the range of 1.75-4.15 GPa.In addition,low density C-S-H was affected by the carbonation degradation more seriously than high density C-S-H.The carbonation reaction led to distinct decrease of the number and size of unhydrated cement paste particles.展开更多
Objective： By the bibliometrical analysis and evaluation of acupuncture theses on auricular acupoint sticking from 2005 to 2014, the analysis was processed from multiple aspects including the types and numbers of dis...Objective： By the bibliometrical analysis and evaluation of acupuncture theses on auricular acupoint sticking from 2005 to 2014, the analysis was processed from multiple aspects including the types and numbers of diseases and effective rates of various diseases, in order to objectively reflect the general situation of clinical application of ear point embedding method in the recent years. Methods： By the bibliometrical analysis, the literature on auricular acupoint sticking in the recent ten years was counted up, analyzed and categorized. Results and Conclusion： Auricular acupoint sticking is used clinically for diseases of 26 systems, including 130 diseases. 74 diseases were singularly treated with auricular acupoint sticking, including the advantageous disease category like insomnia, constipation and obesity, and secondary advantageous disease category like dysmenorrhea, myopia, allergic rhinitis, post-operative pain and acne vulgaris.展开更多
Objective： To observe the clinical efficacy of umbilicus application with Chinese medicine in treating children＇s chronic diarrhea due to food intolerance and the value of healthy diet education. Methods： Eighty ki...Objective： To observe the clinical efficacy of umbilicus application with Chinese medicine in treating children＇s chronic diarrhea due to food intolerance and the value of healthy diet education. Methods： Eighty kids with chronic diarrhea due to food intolerance were recruited from multiple centers and divided by using the random number table into a treatment group of 40 cases and a control group of 40 cases. For both groups, based on the level of serum food-specific immunoglobulin G（Ig-G）, the patients were given unified diet following the healthy diet guidance： safe, alternate, and forbidden, while the treatment group was additionally given umbilicus application with Chinese medicine. The therapeutic efficacy and symptom score of traditional Chinese medicine（TCM） were observed and compared respectively after 1-week, 2-week, 4-week, and 12-week treatment. Results： The diarrhea symptoms and coupled symptoms scores dropped significantly in the two groups after treatment（ all P〈0.05）, and the inter-group comparisons also showed statistical significances（P〈0.05）. The total effective rate was 97.5% in the treatment group versus 77.5% in the control group, and the inter-group difference was statistically significant（P〈0.05）. Conclusion： The healthy diet guidance based on the food intolerance test is effective in helping treat diarrhea, while umbilicus application with Chinese medicine works better in treating diarrhea for kids with chronic diarrhea due to food intolerance and can significantly enhance the therapeutic efficacy.展开更多
基金Supported by the Aeronautical Science Foundation of China(20061453020)Foundation for Basic Research of Northwestern Polytechnical University(03)~~
文摘The flow around airfoil NACA0012 enwrapped by the body-fitted grid is simulated by a coupled doubledistribution-function （DDF） lattice Boltzmann method （LBM） for the compressible Navier-Stokes equations. Firstly, the method is tested by simulating the low Reynolds number flow at Ma =0. 5,a=0. 0, Re=5 000. Then the simulation of flow around the airfoil is carried out at Ma：0. 5, 0. 85, 1.2; a=-0.05, 1.0, 0.0, respectively. And a better result is obtained by using a local refined grid. It reduces the error produced by the grid at Ma=0. 85. Though the inviscid boundary condition is used to avoid the problem of flow transition to turbulence at high Reynolds numbers, the pressure distribution obtained by the simulation agrees well with that of the experimental results. Thus, it proves the reliability of the method and shows its potential for the compressible flow simulation. The suecessful application to the flow around airfoil lays a foundation of the numerical simulation of turbulence.
文摘Haloacetonitrile anions CH2XCN- （X=F, Cl） were studied by HF-SCF, Becke3-LYP, and MP2 methods together with the Dunning＇s basis set aug-cc-PVTZ. The vertical electron attachments to the neutral are endothermic. The geometrically optimized CH2FCN^- is mainly a valence-bounded anion and CH2FCN→CH2CN＋F^- is a nonadiabatic dissociation. This theoretical study in good agreement with the experimental results shows that the Becke3-LYP method is reasonable in describing the electronic structures of anions and dissociative attachment dynamics, while significant differences between MP2 and Becke3-LYP results are shown for the dissociation potential curves of CH2ClCN→CH2CN＋Cl^-.
基金Project(2008BAB32B03) supported by the National Science and Technology Pillar Program during the 11th Five-year Plan Period of China
文摘Based on the pipe transportation of paste-like backfilling system of a certain deep coal mine,its dynamics process was simulated and analyzed.A two-dimensional dynamic model of extraordinary deep and lone pipe was built by GAMBIT,on the basis of which the simulation was done by implicit solver of FLUENT 2ddp.The results show that hydraulic loss of pipe transportation is less than the pressure produced by gravity,which means the backfilling material can flow by itself.When the inlet velocity is 3.2 m/s,the maximum velocity of 4.10 m/s is at the elbow and the maximum velocity in the horizontal pipe is 3.91 m/s,which can both meet the stability requirement.The results of the simulation are proved to be reliable by the residual monitor plotting of related parameter,so it can be concluded that the system of pipe transportation is safe.
文摘The sinomenine hydrochloride （SH） patch, a topical drug delivery system, was prepared and characterized. The in vitro release was studied according to the paddle-over-disk method in the appendix of Chinese Pharmacopeia （appendix XD, 2005）. Stability of SH patch was evaluated at accelerated testing conditions （40 ℃, 75% RH）. Pharmacological and pharmacokinetics study were also performed. It was found that the release of SH from patches depended on pH value of the release medium. There were no significant differences between SH patches stored for 6 mon and those stored for 0 mon in the drug content, initial adhesion, lasting stickiness, peeling strength and in vitro release. SH patches exhibited better anti-inflammatory activity as well as analgesic efficacy. More importantly, primary pharmacokinetic parameters of SH patch, such as Cmax and AUC, were much lower than those of SH solution dosed orally. In conclusion, the patch might be a promising delivery system for SH, which bypassed the gastrointestinal tract and was a convenient, efficacious, safe and non-invasive delivery method.
基金supported by the National Basic Research Program of China ("973" Project) (Grant No. 2009CB623200)the Scientific Research Foundation of the Graduate School of Southeast University (Grant No. YBJJ1113)
文摘Nanoindentation technique was adopted to investigate the chemomechanical properties change of hardened cement paste before and after carbonation.It was found that the mean elastic modulus and mean hardness obviously increase after the carbonation reaction.Specifically,the probability of the elastic modulus showed a sharp reduction for the elastic modulus at the range of 7-34 and 83-160 GPa,in comparison of a large increase for the elastic modulus between 34-83 GPa.For the same reason,the probability of the hardness showed a large decrease when the hardness fell within 0.15-1.75 and 4.15-8.20 GPa and a dramatic increase for the hardness at the range of 1.75-4.15 GPa.In addition,low density C-S-H was affected by the carbonation degradation more seriously than high density C-S-H.The carbonation reaction led to distinct decrease of the number and size of unhydrated cement paste particles.
基金supported by Projects of Shanghai Municipal Commission of Health and Family Planning(No.20124Y009,No.20144Y0153)~~
文摘Objective： By the bibliometrical analysis and evaluation of acupuncture theses on auricular acupoint sticking from 2005 to 2014, the analysis was processed from multiple aspects including the types and numbers of diseases and effective rates of various diseases, in order to objectively reflect the general situation of clinical application of ear point embedding method in the recent years. Methods： By the bibliometrical analysis, the literature on auricular acupoint sticking in the recent ten years was counted up, analyzed and categorized. Results and Conclusion： Auricular acupoint sticking is used clinically for diseases of 26 systems, including 130 diseases. 74 diseases were singularly treated with auricular acupoint sticking, including the advantageous disease category like insomnia, constipation and obesity, and secondary advantageous disease category like dysmenorrhea, myopia, allergic rhinitis, post-operative pain and acne vulgaris.
基金supported by the Key Special Program of Science and Technology During the National Twelfth Five-year Plan(No.2012ZX10005004-003)National Natural Science Foundati on of China(No.81302924)+1 种基金Program of Shanghai Science and Technology Committee(No.15401971100)Special Plan of Shanghai Chinese Medicine Experts(No.ZY3-RCPY-3-1027)~~
文摘Objective： To observe the clinical efficacy of umbilicus application with Chinese medicine in treating children＇s chronic diarrhea due to food intolerance and the value of healthy diet education. Methods： Eighty kids with chronic diarrhea due to food intolerance were recruited from multiple centers and divided by using the random number table into a treatment group of 40 cases and a control group of 40 cases. For both groups, based on the level of serum food-specific immunoglobulin G（Ig-G）, the patients were given unified diet following the healthy diet guidance： safe, alternate, and forbidden, while the treatment group was additionally given umbilicus application with Chinese medicine. The therapeutic efficacy and symptom score of traditional Chinese medicine（TCM） were observed and compared respectively after 1-week, 2-week, 4-week, and 12-week treatment. Results： The diarrhea symptoms and coupled symptoms scores dropped significantly in the two groups after treatment（ all P〈0.05）, and the inter-group comparisons also showed statistical significances（P〈0.05）. The total effective rate was 97.5% in the treatment group versus 77.5% in the control group, and the inter-group difference was statistically significant（P〈0.05）. Conclusion： The healthy diet guidance based on the food intolerance test is effective in helping treat diarrhea, while umbilicus application with Chinese medicine works better in treating diarrhea for kids with chronic diarrhea due to food intolerance and can significantly enhance the therapeutic efficacy.
