赖激素性葡萄膜炎中西医结合治疗的探讨

目的：探讨赖激素性葡萄膜炎的中西医结合治疗方法。方法：对６例（１２只眼）激素依赖性葡萄膜炎经合理使用皮质类固醇，并应用中药温阳补肾，益气养阴进行了治疗。结果：６例患者中有５例在１周内葡萄膜炎得到控制；５例停用皮质类固醇后葡萄膜炎无复发；１２只眼均随访了２年。结论：中西医结合治疗赖激素性葡萄膜炎是一种可取的方法。

Clinical research on treatment of advanced androgen independent prostate cancer with Docetaxel and Thalidomide

Objective:To evaluate the clinical effects and adverse reactions of Docetaxel and Thalidomide in treating advanced androgen independent prostate cancer(AIPC).Methods:12 cases of advanced AIPC were given a combined treatment of Docetaxel and Thalidomide, with Docetaxel 75 mg/m2 on day 1 and Thalidomide 100 mg per day as initial dose and 300 mg as terminal dose by an increase of 50 mg every week.Results:The post-treatment values of prostate specific antigen(PSA) were normal(< 4 ng/L) in 10 patients, less than 50% of pretreatment value in one patient, and no significant change in one patient.The median survival time was 14 months and period of the median symptoms reduction was 16.3 months.Common adverse reactions were tolerable, including nausea, vomiting, leukopenia, anemia and thrombocytopenia.Conclusion:The regimen of Docetaxel combined with Thalidomide was effective and tolerable in the treatment of advanced AIPC.