The development of a pseudo-one pot synthesis of 3(5),4-dinitropyrazole enabled us to use it as a starting material for energetic plasticisers. Its acidic proton allowed simple derivatisation on one of the ring nitr...The development of a pseudo-one pot synthesis of 3(5),4-dinitropyrazole enabled us to use it as a starting material for energetic plasticisers. Its acidic proton allowed simple derivatisation on one of the ring nitrogens. The thermal characteristics of two derivatives were evaluated. For instance, the N-allyl compound was a liquid with very low glass transition temperature, whereas the N-propargyl compound was a sticky solid at ambient temperature. The two compounds were both thermally stable according to STANAG 4582.展开更多
There are many kinds of fires occurring under different conditions. For a specific site, it is difficult to collect sufficient data for analyzing the fire risk. In this paper, we suggest an information diffusion techn...There are many kinds of fires occurring under different conditions. For a specific site, it is difficult to collect sufficient data for analyzing the fire risk. In this paper, we suggest an information diffusion technique to analyze fire risk with a small sample. The information distribution method is applied to change crisp observations into fuzzy sets, and then to effectively construct a fuzzy relationship between fire and surroundings. With the data of Shanghai in winter, we show how to use the technique to analyze the fire risk.展开更多
Two ensemble experiments were conducted using a general atmospheric circulation model. These experiments were used to investigate the impacts of initial snow anomalies over the Tibetan Plateau(TP) on China precipitati...Two ensemble experiments were conducted using a general atmospheric circulation model. These experiments were used to investigate the impacts of initial snow anomalies over the Tibetan Plateau(TP) on China precipitation prediction. In one of the experiments, the initial snow conditions over the TP were climatological values; while in the other experiment, the initial snow anomalies were snow depth estimates derived from the passive microwave remote-sensing data. In the current study, the difference between these two experiments was assessed to evaluate the impact of initial snow anomalies over the TP on simulated precipitation. The results indicated that the model simulation for precipitation over eastern China had certain improvements while applying a more realistic initial snow anomaly, especially for spring precipitation over Northeast China and North China and for summer precipitation over North China and Southeast China. The results suggest that seasonal prediction could be enhanced by using more realistic initial snow conditions over TP, and microwave remote-sensing snow data could be used to initialize climate models and improve the simulation of eastern China precipitation during spring and summer. Further analyses showed that higher snow anomalies over TP cooled the surface, resulting in lower near- surface air temperature over the TP in spring and summer. The surface cooling over TP weakened the Asian summer monsoon and brought more precipitation in South China in spring and more precipitation to Southeast China during summer.展开更多
Needle coke is the starting material for manufacture of premium graphite electrode,which at present cannot be produced by SINOPEC and even other domestic refining enterprises so that the carbon producing plants inside...Needle coke is the starting material for manufacture of premium graphite electrode,which at present cannot be produced by SINOPEC and even other domestic refining enterprises so that the carbon producing plants inside China have to import a significant amount of high-quality needle coke every year.展开更多
Erik Verlinde recently proposed an idea about the thermodynamic origin of gravity.Though this is abeautiful idea, which may resolve many long standing problems in the theories of gravity, it also raises many otherprob...Erik Verlinde recently proposed an idea about the thermodynamic origin of gravity.Though this is abeautiful idea, which may resolve many long standing problems in the theories of gravity, it also raises many otherproblems.In this article I will comment on some of the problems of Verlinde’s proposal with special emphasis on thethermodynamical origin of the principle of relativity.It is found that there is a large group of hidden symmetries ofthermodynamics, which contains the Poincare group of the spacetime for which space is emergent.This explains thethermodynamic origin of the principle of relativity.展开更多
Mass elevation effect (MEE) refers to the thermal effect of huge mountains or plateaus, which causes the tendency for tem- perature-related montane landscape limits to occur at higher elevations in the inner massifs...Mass elevation effect (MEE) refers to the thermal effect of huge mountains or plateaus, which causes the tendency for tem- perature-related montane landscape limits to occur at higher elevations in the inner massifs than on their outer margins. MEE has been widely identified in all large mountains, but how it could be measured and what its main forming-factors are still remain open. This paper, supposing that the local mountain base elevation (MBE) is the main factor of MEE, takes the Qinghai-Tibet Plateau (QTP) as the study area, defines MEE as the temperature difference (AT) between the inner and outer parts of mountain massifs, identifies the main forming factors, and analyzes their contributions to MEE. A total of 73 mountain bases were identified, ranging from 708 m to 5081 m and increasing from the edges to the central parts of the plateau. Climate data (1981-2010) from 134 meteorological stations were used to acquire ATby comparing near-surface air temperature on the main plateau with the free-air temperature at the same altitude and simi- lar latitude outside of the plateau. The AT for the warmest month is averagely 6.15 ~C, over 12~C at Lhatse and Baxoi. A multivariate linear regression model was developed to simulate MEE based on three variables (latitude, annual mean precipitation and MBE), which are all significantly correlated to AT. The model could explain 67.3% of MEE variation, and the contribution rates of three independent variables to MEE are 35.29%, 22.69% and 42.02%, respectively. This confirms that MBE is the main factor of MEE. The intensive MEE of the QTP pushes the 10~C isotherm of the warmest month mean temperature 1300-2000 m higher in the main plateau than in the outer regions, leading the occurrence of the highest timberline (4900 m) and the highest snowline (6200 m) of the Northern Hemisphere in the southeast and southwest of the plateau, respectively.展开更多
Overbased complex sulphonates containing two metals -- sodium and magnesium -- were prepared by using overbased magnesium sulphonate as the starting material. Borated overbased complex sulphonate containing two metals...Overbased complex sulphonates containing two metals -- sodium and magnesium -- were prepared by using overbased magnesium sulphonate as the starting material. Borated overbased complex sulphonate containing two metals was synthesized by reaction of boric acid with the corresponding sulphonate. The total base number (TBN) of overbased complex sulphonates decreased compared with that of magnesium sulphonate, while TBN of borated overbased complex sulphonate further decreased. The detergency, anti-oxidation and extreme pressure performances of overbased complex sulphonates were improved compared with those of overbased magnesium sulphonate; the anti-oxidation and extreme pressure performances of borated overbased complex sulphonates were further improved whereas its detergency was reduced.展开更多
The possibility and causes of flight accidents by operational error/deviation in takeoff are analyzed in this paper. The following three stages are each described individually: before liftoff, near liftoff and initial...The possibility and causes of flight accidents by operational error/deviation in takeoff are analyzed in this paper. The following three stages are each described individually: before liftoff, near liftoff and initial climb. Relations of accident/incident causal factors by operational error with intrinsical flight mechanics are discussed.展开更多
Fluvoxamine maleate is an excellent antidepressive drug. In the literatures, it was synthesized by the use of 4-(trifluoromethyl) aniline or 4-(trifluoromethyl) benzonitrile as starting materials and 5-methoxy-4'...Fluvoxamine maleate is an excellent antidepressive drug. In the literatures, it was synthesized by the use of 4-(trifluoromethyl) aniline or 4-(trifluoromethyl) benzonitrile as starting materials and 5-methoxy-4'-(trifluoromethyl-phenyl) valerophenone as a key intermediate. However, the methods in literatures have some disadvantages, such as the use of expensive materials, heavy pollution of environment, long reaction time and low yield of the product (only 30-40% overall yield). We herein report an environmentally friendly synthetic method of fluvoxamine maleate, which used 4-(trifluoromethyl) benzoic acid and tetrahydrofuran as starting materials and FeCI3 as catalyst for the coupling of acid chloride with Grignard reagent. The fluvoxamine maleate was synthesized in 46% overall yield, through the oximation, etheration and salification of the intermediate successively.This method has some advantages, such as the use of commercially available materials, low cost, short production period (12-14 h), high yield and light pollution.展开更多
The quality of the scanning tip is crucial for tip-enhanced Raman spectroscopy(TERS)experiments towards large signal enhancement and high spatial resolution.In this work,we report a controllable fabrication method to ...The quality of the scanning tip is crucial for tip-enhanced Raman spectroscopy(TERS)experiments towards large signal enhancement and high spatial resolution.In this work,we report a controllable fabrication method to prepare TERS-active tips by modifying the tip apex at the atomic scale,and propose two important criteria to in-situ judge the tip’s TERS activity for tip-enhanced Raman measurements.One criterion is based on the downshift of the first image potential state to monitor the coupling between the far-field incident laser and near-field plasmon;the other is based on the appearance of the low-wavenumber Raman peaks associated with an atomistic protrusion at the tip apex to judge the coupling efficiency of emissions from the near field to the far field.This work provides an effective method to quickly fabricate and judge TERS-active tips before real TERS experiments on target molecules and other materials,which is believed to be instrumental for the development of TERS and other tip-enhanced spectroscopic techniques.展开更多
Mathematical geophone (MG) and equal-time stacking (ETS) principles are used to implement seismic prestack forward modeling with irregular surfaces using the oneway acoustic wave-equation. This method receives sei...Mathematical geophone (MG) and equal-time stacking (ETS) principles are used to implement seismic prestack forward modeling with irregular surfaces using the oneway acoustic wave-equation. This method receives seismic primary reflections from the subsurface using a set of virtual MGs. The receivers can be located anywhere on an irregular observing surface. Moreover, the ETS method utilizes the one-way acoustic wave equation to easily and quickly image and extrapolate seismic reflection data. The method is illustrated using high single-noise ratio common shot gathers computed by numerical forward modeling of two simple models, one with a flat surface and one with an irregular surface, and a complex normal fault model. A prestack depth migration method for irregular surface topography was used to reoroduce the normal fault model with high accuracy.展开更多
The movement principle of sidewalls and floor of extraction opening is analyzed, it is found that floor heave not only has something to do with the floor strata, but sidewalls. The effect of sidewall anchor and corner...The movement principle of sidewalls and floor of extraction opening is analyzed, it is found that floor heave not only has something to do with the floor strata, but sidewalls. The effect of sidewall anchor and corner anchor is studied, the mechanical principle of reinforcing sidewalls and corners is put forward and applied in engineering practice.展开更多
We recently presented the case of a first century AD young woman, found in the archaeological site of Cosa, showing clinical signs of malnutrition, such as short height, osteoporosis, dental enamel hypoplasia and crib...We recently presented the case of a first century AD young woman, found in the archaeological site of Cosa, showing clinical signs of malnutrition, such as short height, osteoporosis, dental enamel hypoplasia and cribra orbitalia, indirect sign of anemia, all strongly suggestive for celiac disease (CD). However, whether these findings were actually associated to CD was not shown based on genetic parameters. To investigate her human leukocyte antigen (HLA) class Ⅱ polymorphism, we extracted DNA from a bone sample and a tooth and genotyped HLA using three HLA-tagging single nucleotide polymorphisms for DQ8, DQ2.2 and DQ2.5, specifically associated to CD. She displayed HLA DQ 2.5, the haplotype associated to the highest risk of CD. This isthe first report showing the presence of a HLA haplotype compatible for CD in archaeological specimens.展开更多
文摘The development of a pseudo-one pot synthesis of 3(5),4-dinitropyrazole enabled us to use it as a starting material for energetic plasticisers. Its acidic proton allowed simple derivatisation on one of the ring nitrogens. The thermal characteristics of two derivatives were evaluated. For instance, the N-allyl compound was a liquid with very low glass transition temperature, whereas the N-propargyl compound was a sticky solid at ambient temperature. The two compounds were both thermally stable according to STANAG 4582.
文摘There are many kinds of fires occurring under different conditions. For a specific site, it is difficult to collect sufficient data for analyzing the fire risk. In this paper, we suggest an information diffusion technique to analyze fire risk with a small sample. The information distribution method is applied to change crisp observations into fuzzy sets, and then to effectively construct a fuzzy relationship between fire and surroundings. With the data of Shanghai in winter, we show how to use the technique to analyze the fire risk.
基金supported by the National Basic Research Program of China (Grant No. 2009CB421407)the Special Fund for Public Welfare (Meteorology) (Grant No. GYHY200906018)+1 种基金"Strategic Priority Research Program-Climate Change: Carbon Budget and Related Issues" of the Chinese Academy of Sciences (Grant No. XDA05110201)the National Key Technologies R&D Program of China (Grant No. 2007BAC29B03)
文摘Two ensemble experiments were conducted using a general atmospheric circulation model. These experiments were used to investigate the impacts of initial snow anomalies over the Tibetan Plateau(TP) on China precipitation prediction. In one of the experiments, the initial snow conditions over the TP were climatological values; while in the other experiment, the initial snow anomalies were snow depth estimates derived from the passive microwave remote-sensing data. In the current study, the difference between these two experiments was assessed to evaluate the impact of initial snow anomalies over the TP on simulated precipitation. The results indicated that the model simulation for precipitation over eastern China had certain improvements while applying a more realistic initial snow anomaly, especially for spring precipitation over Northeast China and North China and for summer precipitation over North China and Southeast China. The results suggest that seasonal prediction could be enhanced by using more realistic initial snow conditions over TP, and microwave remote-sensing snow data could be used to initialize climate models and improve the simulation of eastern China precipitation during spring and summer. Further analyses showed that higher snow anomalies over TP cooled the surface, resulting in lower near- surface air temperature over the TP in spring and summer. The surface cooling over TP weakened the Asian summer monsoon and brought more precipitation in South China in spring and more precipitation to Southeast China during summer.
文摘Needle coke is the starting material for manufacture of premium graphite electrode,which at present cannot be produced by SINOPEC and even other domestic refining enterprises so that the carbon producing plants inside China have to import a significant amount of high-quality needle coke every year.
基金Supported by the National Natural Science Foundation of China under Grant No.10875059
文摘Erik Verlinde recently proposed an idea about the thermodynamic origin of gravity.Though this is abeautiful idea, which may resolve many long standing problems in the theories of gravity, it also raises many otherproblems.In this article I will comment on some of the problems of Verlinde’s proposal with special emphasis on thethermodynamical origin of the principle of relativity.It is found that there is a large group of hidden symmetries ofthermodynamics, which contains the Poincare group of the spacetime for which space is emergent.This explains thethermodynamic origin of the principle of relativity.
基金National Natural Science Foundation of China(No.41571099,41030528)
文摘Mass elevation effect (MEE) refers to the thermal effect of huge mountains or plateaus, which causes the tendency for tem- perature-related montane landscape limits to occur at higher elevations in the inner massifs than on their outer margins. MEE has been widely identified in all large mountains, but how it could be measured and what its main forming-factors are still remain open. This paper, supposing that the local mountain base elevation (MBE) is the main factor of MEE, takes the Qinghai-Tibet Plateau (QTP) as the study area, defines MEE as the temperature difference (AT) between the inner and outer parts of mountain massifs, identifies the main forming factors, and analyzes their contributions to MEE. A total of 73 mountain bases were identified, ranging from 708 m to 5081 m and increasing from the edges to the central parts of the plateau. Climate data (1981-2010) from 134 meteorological stations were used to acquire ATby comparing near-surface air temperature on the main plateau with the free-air temperature at the same altitude and simi- lar latitude outside of the plateau. The AT for the warmest month is averagely 6.15 ~C, over 12~C at Lhatse and Baxoi. A multivariate linear regression model was developed to simulate MEE based on three variables (latitude, annual mean precipitation and MBE), which are all significantly correlated to AT. The model could explain 67.3% of MEE variation, and the contribution rates of three independent variables to MEE are 35.29%, 22.69% and 42.02%, respectively. This confirms that MBE is the main factor of MEE. The intensive MEE of the QTP pushes the 10~C isotherm of the warmest month mean temperature 1300-2000 m higher in the main plateau than in the outer regions, leading the occurrence of the highest timberline (4900 m) and the highest snowline (6200 m) of the Northern Hemisphere in the southeast and southwest of the plateau, respectively.
文摘Overbased complex sulphonates containing two metals -- sodium and magnesium -- were prepared by using overbased magnesium sulphonate as the starting material. Borated overbased complex sulphonate containing two metals was synthesized by reaction of boric acid with the corresponding sulphonate. The total base number (TBN) of overbased complex sulphonates decreased compared with that of magnesium sulphonate, while TBN of borated overbased complex sulphonate further decreased. The detergency, anti-oxidation and extreme pressure performances of overbased complex sulphonates were improved compared with those of overbased magnesium sulphonate; the anti-oxidation and extreme pressure performances of borated overbased complex sulphonates were further improved whereas its detergency was reduced.
文摘The possibility and causes of flight accidents by operational error/deviation in takeoff are analyzed in this paper. The following three stages are each described individually: before liftoff, near liftoff and initial climb. Relations of accident/incident causal factors by operational error with intrinsical flight mechanics are discussed.
文摘Fluvoxamine maleate is an excellent antidepressive drug. In the literatures, it was synthesized by the use of 4-(trifluoromethyl) aniline or 4-(trifluoromethyl) benzonitrile as starting materials and 5-methoxy-4'-(trifluoromethyl-phenyl) valerophenone as a key intermediate. However, the methods in literatures have some disadvantages, such as the use of expensive materials, heavy pollution of environment, long reaction time and low yield of the product (only 30-40% overall yield). We herein report an environmentally friendly synthetic method of fluvoxamine maleate, which used 4-(trifluoromethyl) benzoic acid and tetrahydrofuran as starting materials and FeCI3 as catalyst for the coupling of acid chloride with Grignard reagent. The fluvoxamine maleate was synthesized in 46% overall yield, through the oximation, etheration and salification of the intermediate successively.This method has some advantages, such as the use of commercially available materials, low cost, short production period (12-14 h), high yield and light pollution.
基金supported by the National Key R&D Program of China(No.2016YFA0200600)the National Natural Science Foundation of China(No.21790352,No.22174135)+1 种基金the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB36000000)Anhui Initiative in Quantum Information Technologies(No.AHY090100)。
文摘The quality of the scanning tip is crucial for tip-enhanced Raman spectroscopy(TERS)experiments towards large signal enhancement and high spatial resolution.In this work,we report a controllable fabrication method to prepare TERS-active tips by modifying the tip apex at the atomic scale,and propose two important criteria to in-situ judge the tip’s TERS activity for tip-enhanced Raman measurements.One criterion is based on the downshift of the first image potential state to monitor the coupling between the far-field incident laser and near-field plasmon;the other is based on the appearance of the low-wavenumber Raman peaks associated with an atomistic protrusion at the tip apex to judge the coupling efficiency of emissions from the near field to the far field.This work provides an effective method to quickly fabricate and judge TERS-active tips before real TERS experiments on target molecules and other materials,which is believed to be instrumental for the development of TERS and other tip-enhanced spectroscopic techniques.
基金This work was funded by National Natural Science Foundation of China (No. 40474044).
文摘Mathematical geophone (MG) and equal-time stacking (ETS) principles are used to implement seismic prestack forward modeling with irregular surfaces using the oneway acoustic wave-equation. This method receives seismic primary reflections from the subsurface using a set of virtual MGs. The receivers can be located anywhere on an irregular observing surface. Moreover, the ETS method utilizes the one-way acoustic wave equation to easily and quickly image and extrapolate seismic reflection data. The method is illustrated using high single-noise ratio common shot gathers computed by numerical forward modeling of two simple models, one with a flat surface and one with an irregular surface, and a complex normal fault model. A prestack depth migration method for irregular surface topography was used to reoroduce the normal fault model with high accuracy.
文摘The movement principle of sidewalls and floor of extraction opening is analyzed, it is found that floor heave not only has something to do with the floor strata, but sidewalls. The effect of sidewall anchor and corner anchor is studied, the mechanical principle of reinforcing sidewalls and corners is put forward and applied in engineering practice.
文摘We recently presented the case of a first century AD young woman, found in the archaeological site of Cosa, showing clinical signs of malnutrition, such as short height, osteoporosis, dental enamel hypoplasia and cribra orbitalia, indirect sign of anemia, all strongly suggestive for celiac disease (CD). However, whether these findings were actually associated to CD was not shown based on genetic parameters. To investigate her human leukocyte antigen (HLA) class Ⅱ polymorphism, we extracted DNA from a bone sample and a tooth and genotyped HLA using three HLA-tagging single nucleotide polymorphisms for DQ8, DQ2.2 and DQ2.5, specifically associated to CD. She displayed HLA DQ 2.5, the haplotype associated to the highest risk of CD. This isthe first report showing the presence of a HLA haplotype compatible for CD in archaeological specimens.