Background: Psoriasis is a common dermatological disease with erythematous plaques where articular and extra articular findings (tenosynovitis and enthesitis) may well accompany. The aim of this current study was to e...Background: Psoriasis is a common dermatological disease with erythematous plaques where articular and extra articular findings (tenosynovitis and enthesitis) may well accompany. The aim of this current study was to evaluate the Achilles’ tendon of psoriasis patients with ultrasonography. Methods: The study comprised 30 psoriasis patients and 20 healthy controls. Ankle ultrasonography was performed with posterior approach, the joint in neutral or in a little dorsiflexed position. The statistical analysis was carried out with a Student’ s t- test and Spearman correlation tests. Results: The mean values of Achilles’ tendon thickness of two groups were compared: the psoriatic group was found to have thicker tendon measurements (P = 0.00). The tendons of the patients with radiologically proven enthesopathy were found to be even thicker (P=0.001). Conclusions: We encourage the use of diagnostic ultrasonography for evaluation of enthesopathy manifestations in psoriasis patients as an adjunct to conventional methods owing to its convenience and promising results.展开更多
Psoriasis is clinically a heterogeneous disease. Detailed evaluation of phenotype at disease onset is lacking. This study is a baseline characterization of 400 adult individuals with first time incidence of psoriasis ...Psoriasis is clinically a heterogeneous disease. Detailed evaluation of phenotype at disease onset is lacking. This study is a baseline characterization of 400 adult individuals with first time incidence of psoriasis on non- hairy skin, describing clinical phenotypes and putative environmental triggers at disease onset. In total, 74 patients with guttate and 326 patients with non- guttate phenotype, the majority with plaque psoriasis, were included. Guttate phenotype was associated with younger age and recent infection in 84% , where acute streptococcal pharyngitis was verified in 63% . The predominating factor associated with onset of plaque psoriasis was a recent life crisis (46% ). A positive family history for psoriasis was approximately the same in both groups. Psoriasis arthropathy was diagnosed in 5% of guttate and 15% of non- guttate patients, with enthesopathy being the dominant symptom among guttate patients. This study confirms the strong link between on set of guttatepsorias is phenotype and streptococcal throat infection, whereas onset of plaque psoriasis was highly associated with a preceding distinct stressful life event. Longitudinal follow- up of the patients will provide robust information about disease development and response to treatment.展开更多
文摘Background: Psoriasis is a common dermatological disease with erythematous plaques where articular and extra articular findings (tenosynovitis and enthesitis) may well accompany. The aim of this current study was to evaluate the Achilles’ tendon of psoriasis patients with ultrasonography. Methods: The study comprised 30 psoriasis patients and 20 healthy controls. Ankle ultrasonography was performed with posterior approach, the joint in neutral or in a little dorsiflexed position. The statistical analysis was carried out with a Student’ s t- test and Spearman correlation tests. Results: The mean values of Achilles’ tendon thickness of two groups were compared: the psoriatic group was found to have thicker tendon measurements (P = 0.00). The tendons of the patients with radiologically proven enthesopathy were found to be even thicker (P=0.001). Conclusions: We encourage the use of diagnostic ultrasonography for evaluation of enthesopathy manifestations in psoriasis patients as an adjunct to conventional methods owing to its convenience and promising results.
文摘Psoriasis is clinically a heterogeneous disease. Detailed evaluation of phenotype at disease onset is lacking. This study is a baseline characterization of 400 adult individuals with first time incidence of psoriasis on non- hairy skin, describing clinical phenotypes and putative environmental triggers at disease onset. In total, 74 patients with guttate and 326 patients with non- guttate phenotype, the majority with plaque psoriasis, were included. Guttate phenotype was associated with younger age and recent infection in 84% , where acute streptococcal pharyngitis was verified in 63% . The predominating factor associated with onset of plaque psoriasis was a recent life crisis (46% ). A positive family history for psoriasis was approximately the same in both groups. Psoriasis arthropathy was diagnosed in 5% of guttate and 15% of non- guttate patients, with enthesopathy being the dominant symptom among guttate patients. This study confirms the strong link between on set of guttatepsorias is phenotype and streptococcal throat infection, whereas onset of plaque psoriasis was highly associated with a preceding distinct stressful life event. Longitudinal follow- up of the patients will provide robust information about disease development and response to treatment.
