不同联合手术方式对白内障合并闭角型青光眼的疗效分析

目的: 观察超声乳化白内障摘除人工晶状体植入术联合小梁切除术,超声乳化白内障摘除人工晶状体植入术联合房角分离术治疗白内障合并闭角型青光眼的临床疗效,为治疗白内障合并闭角型青光眼提供可靠方法。方法: 收集白内障合并闭角型青光眼患者78例106眼,将其随机分为两组:其中A组患者40例56眼,采用超声乳化白内障摘除人工晶状体植入术联合小梁切除术治疗;B组患者38例50眼,采用超声乳化白内障摘除人工晶状体植入术联合房角分离术治疗,对其疗效进行对比分析,观察治疗前后视力、眼压、前房深度、房角的变化及并发症的发生率。结果: 两组手术顺利,视力、眼压、前房深度、房角变化在手术前后具有显著的差异(P<0.05)。两组手术后疗效的比较,房角镜检查:A组56眼房角完全开放的49眼;B组50眼房角360°开放的44眼,两组间无统计学差异。术前前房深度:A组为1.73±0.42mm,B组为1.78±0.39mm;术后前房深度:A组为3.25±0.36mm,B组为2.91±0.53mm,两组间有统计学差异(P<0.05)。A组并发症发生率明显高于B组。结论: 超声乳化白内障摘除人工晶状体植入术联合房角分离术治疗白内障合并闭角型青光眼可明显地提高视力,有效地控制眼压,减少手术早期并发症,且操作简便,可广泛运用。

Changes of tear film and tear secretion after phacoemulsification in diabetic patients

Objective: To evaluate tear film stability and tear secretion in patients with diabetes after phacoemulsification. Methods: Twenty-five diabetic cataract patients and 20 age-matched non-diabetic cataract patients as control underwent pha- coemulsification. Tear film break-up time (TFBUT), Schirmer I test (SIT), corneal fluorescein staining, and dry eye symptoms were measured pre- and postoperatively. Results: Diabetics had a decreased preoperative TFBUT and SIT. TFBUT was reduced on Day 1 and recovered on Day 180 postoperatively in both groups. SIT was increased after phacoemulsification, but returned to preoperative levels by Day 180 in non-diabetics, whereas it was lower than preoperative level in diabetics. Positive corneal fluo- rescein staining was elevated in both groups, and returned to preoperative levels only in controls. Dry eye symptoms were similar to fluorescein staining in both groups. Conclusion: Tear secretion was reduced in diabetic cataract patients after phacoe- mulsification, which worsened dry eye symptoms and predisposed those patients to ocular damage.