研究声触诊组织量化技术评价肝纤维化的应用价值,使用西门子(ACUSON S 2000)超声成像系统的声触诊组织量化技术检测158例受检者(病理证实的无肝硬化的乙肝患者68例,肝硬化患者40例及正常对照组50例)肝右叶的横向剪切波速,结果显示:3组...研究声触诊组织量化技术评价肝纤维化的应用价值,使用西门子(ACUSON S 2000)超声成像系统的声触诊组织量化技术检测158例受检者(病理证实的无肝硬化的乙肝患者68例,肝硬化患者40例及正常对照组50例)肝右叶的横向剪切波速,结果显示:3组受检者的肝右叶感兴趣区横向剪切波速经统计学检验F值为4.83,各组之间比较有显著差异(P<0.05),随着慢性肝病程度的加重,横向剪切波速增加,两者有一定相关性,表明声触诊组织量化技术可无创反映肝组织的弹性硬度,间接评估肝纤维化,具有潜在的临床应用价值。展开更多
A new ultrasound contrast imaging technique was proposed for eliminating the harmonic components from the emission signal transmitted by the broadband ultrasonic system.Reversal phase-inversion pulse was used for the ...A new ultrasound contrast imaging technique was proposed for eliminating the harmonic components from the emission signal transmitted by the broadband ultrasonic system.Reversal phase-inversion pulse was used for the first time to separate the contrast harmonics from the harmonics in the emission signal to improve the detection of contrast micro-bubbles.Based on the nonlinear acoustic theory of finite-amplitude effects and the associated distortion of the propagating wave,the Bessel-Fubini series model was applied to describe the nonlinear propagation effects of the reversal phase-inversion pulse,and the Church's equation for zero-thickness encapsulation model was used to produce the scattering-pulse of the bubble.For harmonic imaging,the experiment was performed using a 64-element linear array,which was simulated by Field II.The results show that the harmonic components from the emission signal can be completely cancelled,and the harmonics generated by the nonlinear propagation of the wave through the tissue,can be reduced by 15-30 dB.Compared with the short pulse,the reversal phase-inversion pulse can improve the contrast and definition of the harmonic image significantly.展开更多
文摘研究声触诊组织量化技术评价肝纤维化的应用价值,使用西门子(ACUSON S 2000)超声成像系统的声触诊组织量化技术检测158例受检者(病理证实的无肝硬化的乙肝患者68例,肝硬化患者40例及正常对照组50例)肝右叶的横向剪切波速,结果显示:3组受检者的肝右叶感兴趣区横向剪切波速经统计学检验F值为4.83,各组之间比较有显著差异(P<0.05),随着慢性肝病程度的加重,横向剪切波速增加,两者有一定相关性,表明声触诊组织量化技术可无创反映肝组织的弹性硬度,间接评估肝纤维化,具有潜在的临床应用价值。
基金Project(20070533131) supported by the National Research Foundation for the Doctoral Program of Higher Education of ChinaProject(50275150) supported by the National Natural Science Foundation of China
文摘A new ultrasound contrast imaging technique was proposed for eliminating the harmonic components from the emission signal transmitted by the broadband ultrasonic system.Reversal phase-inversion pulse was used for the first time to separate the contrast harmonics from the harmonics in the emission signal to improve the detection of contrast micro-bubbles.Based on the nonlinear acoustic theory of finite-amplitude effects and the associated distortion of the propagating wave,the Bessel-Fubini series model was applied to describe the nonlinear propagation effects of the reversal phase-inversion pulse,and the Church's equation for zero-thickness encapsulation model was used to produce the scattering-pulse of the bubble.For harmonic imaging,the experiment was performed using a 64-element linear array,which was simulated by Field II.The results show that the harmonic components from the emission signal can be completely cancelled,and the harmonics generated by the nonlinear propagation of the wave through the tissue,can be reduced by 15-30 dB.Compared with the short pulse,the reversal phase-inversion pulse can improve the contrast and definition of the harmonic image significantly.
