Endoscopic ultrasound(EUS)-guided biliary drainage has emerged as a minimally invasive alternative to percutaneous and surgical interventions for patients with biliary obstruction who had failed endoscopic retrograde ...Endoscopic ultrasound(EUS)-guided biliary drainage has emerged as a minimally invasive alternative to percutaneous and surgical interventions for patients with biliary obstruction who had failed endoscopic retrograde cholangiopancreatography(ERCP).EUSguided biliary drainage has become feasible due to the development of large channel curvilinear therapeutic echo-endoscopes and the use of real-time ultrasound and fluoroscopy imaging in addition to standard ERCP devices and techniques.EUS-guided biliary drainage is an attractive option because of its minimally invasive,single step procedure which provides internal biliary decompression.Multiple investigators have reported high success and low complication rates.Unfortunately,high quality prospective data are still lacking.We provide detailed review of the use of EUS for biliary drainage from the perspective of practicing endoscopists with specific focus on the technical aspects of the procedure.展开更多
The optical coupling of superconducting nanowire single-photon detectors (SNSPDs) has always been restricted to a single-mode fiber for a limited detection area. In this study, for enhancing photon coupling, a dual-...The optical coupling of superconducting nanowire single-photon detectors (SNSPDs) has always been restricted to a single-mode fiber for a limited detection area. In this study, for enhancing photon coupling, a dual-lens system operating at 2.2 K was used to compress the beam size on the basis of the Gaussian beam theory and geometric approximation. A magnification of approximately 0.3 was obtained, and a focused spot with diameter of approximately 10 ~m was measured from a multimode fiber. Assisted with the compressed beam, a system efficiency of 55 % (1550 nm) was achieved for a SNSPD with a detection area of 10 μm × 10 μm and 62.5 pm multimode fiber coupling. At the same time, a high speed of 106 MHz was measured with the proposed system. The realization of a highly compressed optical beam reduced the optical coupling requirement and helped maintain a high speed for the SNSPD.展开更多
文摘Endoscopic ultrasound(EUS)-guided biliary drainage has emerged as a minimally invasive alternative to percutaneous and surgical interventions for patients with biliary obstruction who had failed endoscopic retrograde cholangiopancreatography(ERCP).EUSguided biliary drainage has become feasible due to the development of large channel curvilinear therapeutic echo-endoscopes and the use of real-time ultrasound and fluoroscopy imaging in addition to standard ERCP devices and techniques.EUS-guided biliary drainage is an attractive option because of its minimally invasive,single step procedure which provides internal biliary decompression.Multiple investigators have reported high success and low complication rates.Unfortunately,high quality prospective data are still lacking.We provide detailed review of the use of EUS for biliary drainage from the perspective of practicing endoscopists with specific focus on the technical aspects of the procedure.
基金supported by the National Basic Research Program of China(2011CBA02)the National Natural Science Foundation of China(61471189,11227904 and 61101012)
文摘The optical coupling of superconducting nanowire single-photon detectors (SNSPDs) has always been restricted to a single-mode fiber for a limited detection area. In this study, for enhancing photon coupling, a dual-lens system operating at 2.2 K was used to compress the beam size on the basis of the Gaussian beam theory and geometric approximation. A magnification of approximately 0.3 was obtained, and a focused spot with diameter of approximately 10 ~m was measured from a multimode fiber. Assisted with the compressed beam, a system efficiency of 55 % (1550 nm) was achieved for a SNSPD with a detection area of 10 μm × 10 μm and 62.5 pm multimode fiber coupling. At the same time, a high speed of 106 MHz was measured with the proposed system. The realization of a highly compressed optical beam reduced the optical coupling requirement and helped maintain a high speed for the SNSPD.