AIM:To investigate stapled transanal rectal resection (STARR) procedures as surgical techniques for obstructed defecation syndrome (ODS) by analyzing specimen evaluation,anorectal manometry,endoanal ultrasonography an...AIM:To investigate stapled transanal rectal resection (STARR) procedures as surgical techniques for obstructed defecation syndrome (ODS) by analyzing specimen evaluation,anorectal manometry,endoanal ultrasonography and clinical follow-up.METHODS:From January to December 2007,we have treated 30 patients.Fifteen treated with double PPH-01 staplers and 15 treated using new CCS 30 contour.Resected specimen were measured with respect to average surface and volume.All patients have been evaluated at 24 mo with clinical examination,anorectal manometry and endoanal ultrasonography.RESULTS:Average surface in the CCS 30 group was 54.5 cm2 statistically different when compared to the STARR group (36.92 cm2).The average volume in the CCS 30 group was 29.8 cc,while in the PPH-01 it was23.8 cc and difference was statistically significant.The mean hospital stay in the CCS 30 group was 3.1 d,while in the PPH-01 group the median hospital stay was 3.4 d.As regards the long-term follow-up,an overall satisfactory rate of 83.3% (25/30) was achieved.Endoanal ultrasonography performed 1 year following surgery was considered normal in both of the studied groups.Mean resting pressure was higher than the preoperative value (67.2 mmHg in the STARR group and 65.7 mmHg in the CCS30 group vs 54.7 mmHg and 55.3 mmHg,respectively).Resting and squeezing pressures were lower in those patients not satisfied,but data are not statistically significant.CONCLUSION:The STARR procedure with two PPH-01 is a safe surgical procedure to correct ODS.The new Contour CCS 30 could help to increase the amount of the resected tissue without differences in early complications,post-operative pain and in hospital stay compared to the STARR with two PPH-01 technique.展开更多
This paper firstly analyzes the property of the low frequency electromagnetic wave, which can penetrate many types of non-metallic materials, and the ability of Ultra-Wide Band (UWB) impulse signal which has high rang...This paper firstly analyzes the property of the low frequency electromagnetic wave, which can penetrate many types of non-metallic materials, and the ability of Ultra-Wide Band (UWB) impulse signal which has high range resolution. Then the methods are discussed for conducting surveillance through walls, detecting and locating the moving persons behind the partitions. The schematic diagram of Through-Wall Detecting Radar (TWDR) and the models of moving target are shown and the principle of detecting the moving target is also provided with coherent superimposing technique on a range gate. Finally an algorithm for estimating the location of targets is given. The performance of TWDR is validated by the experiments of penetrating a wood block, a red brick wall and a reinforced concrete wall.展开更多
Cancer cells differ from normal cells in various parameters, and these differences are caused by genomic mutations and consequential altered gene expression. The genetic and functional heterogeneity of tumor cells is ...Cancer cells differ from normal cells in various parameters, and these differences are caused by genomic mutations and consequential altered gene expression. The genetic and functional heterogeneity of tumor cells is a major challenge in cancer research, detection, and effective treatment. As such, the use of diagnostic methods is important to reveal this heterogeneity at the single-cell level. Droplet microfluidic devices are effective tools that provide exceptional sensitivity for analyzing single cells and molecules. In this review, we highlight two novel methods that employ droplet microfluidics for ultrasensitive detection of nucleic acids and protein markers in cancer cells. We also discuss the future practical applications of these methods.展开更多
We present a computerized method for the semi-automatic detection of contours in ultrasound images. The novelty of our study is the introduction of a fast and efficient image function relating to parametric active con...We present a computerized method for the semi-automatic detection of contours in ultrasound images. The novelty of our study is the introduction of a fast and efficient image function relating to parametric active contour models. This new function is a combination of the gray-level information and first-order statistical features, called standard deviation parameters. In a comprehensive study, the developed algorithm and the efficiency of segmentation were first tested for synthetic images. Tests were also performed on breast and liver ultrasound images. The proposed method was compared with the watershed approach to show its efficiency. The performance of the segmentation was estimated using the area error rate. Using the standard devia- tion textural feature and a 5x5 kernel, our curve evolution was able to produce results close to the minimal area error rate （namely 8.88% for breast images and 10.82% for liver images）. The image resolution was evaluated using the con- trast-to-gradient method. The experiments showed promising segmentation results.展开更多
文摘AIM:To investigate stapled transanal rectal resection (STARR) procedures as surgical techniques for obstructed defecation syndrome (ODS) by analyzing specimen evaluation,anorectal manometry,endoanal ultrasonography and clinical follow-up.METHODS:From January to December 2007,we have treated 30 patients.Fifteen treated with double PPH-01 staplers and 15 treated using new CCS 30 contour.Resected specimen were measured with respect to average surface and volume.All patients have been evaluated at 24 mo with clinical examination,anorectal manometry and endoanal ultrasonography.RESULTS:Average surface in the CCS 30 group was 54.5 cm2 statistically different when compared to the STARR group (36.92 cm2).The average volume in the CCS 30 group was 29.8 cc,while in the PPH-01 it was23.8 cc and difference was statistically significant.The mean hospital stay in the CCS 30 group was 3.1 d,while in the PPH-01 group the median hospital stay was 3.4 d.As regards the long-term follow-up,an overall satisfactory rate of 83.3% (25/30) was achieved.Endoanal ultrasonography performed 1 year following surgery was considered normal in both of the studied groups.Mean resting pressure was higher than the preoperative value (67.2 mmHg in the STARR group and 65.7 mmHg in the CCS30 group vs 54.7 mmHg and 55.3 mmHg,respectively).Resting and squeezing pressures were lower in those patients not satisfied,but data are not statistically significant.CONCLUSION:The STARR procedure with two PPH-01 is a safe surgical procedure to correct ODS.The new Contour CCS 30 could help to increase the amount of the resected tissue without differences in early complications,post-operative pain and in hospital stay compared to the STARR with two PPH-01 technique.
基金Supported by the National 863 Program (No.2001AA132020).
文摘This paper firstly analyzes the property of the low frequency electromagnetic wave, which can penetrate many types of non-metallic materials, and the ability of Ultra-Wide Band (UWB) impulse signal which has high range resolution. Then the methods are discussed for conducting surveillance through walls, detecting and locating the moving persons behind the partitions. The schematic diagram of Through-Wall Detecting Radar (TWDR) and the models of moving target are shown and the principle of detecting the moving target is also provided with coherent superimposing technique on a range gate. Finally an algorithm for estimating the location of targets is given. The performance of TWDR is validated by the experiments of penetrating a wood block, a red brick wall and a reinforced concrete wall.
基金supported by a grant from the National Institutes of Health (Grant No. NIH/NGRR 1R21RR025371–01 to IS)
文摘Cancer cells differ from normal cells in various parameters, and these differences are caused by genomic mutations and consequential altered gene expression. The genetic and functional heterogeneity of tumor cells is a major challenge in cancer research, detection, and effective treatment. As such, the use of diagnostic methods is important to reveal this heterogeneity at the single-cell level. Droplet microfluidic devices are effective tools that provide exceptional sensitivity for analyzing single cells and molecules. In this review, we highlight two novel methods that employ droplet microfluidics for ultrasensitive detection of nucleic acids and protein markers in cancer cells. We also discuss the future practical applications of these methods.
基金supported by the Project SOP HRD-EFICIENT 61445/2009 of University Dunarea de Jos of Galati,Romania
文摘We present a computerized method for the semi-automatic detection of contours in ultrasound images. The novelty of our study is the introduction of a fast and efficient image function relating to parametric active contour models. This new function is a combination of the gray-level information and first-order statistical features, called standard deviation parameters. In a comprehensive study, the developed algorithm and the efficiency of segmentation were first tested for synthetic images. Tests were also performed on breast and liver ultrasound images. The proposed method was compared with the watershed approach to show its efficiency. The performance of the segmentation was estimated using the area error rate. Using the standard devia- tion textural feature and a 5x5 kernel, our curve evolution was able to produce results close to the minimal area error rate （namely 8.88% for breast images and 10.82% for liver images）. The image resolution was evaluated using the con- trast-to-gradient method. The experiments showed promising segmentation results.
