AIM： To assess if software assisted-contrast-enhanced ultrasonography （CEUS） provides reproducible perfu- sion parameters of hepatic parenchyma in patients af- fected by chronic liver disease. METHODS： Forty patie...AIM： To assess if software assisted-contrast-enhanced ultrasonography （CEUS） provides reproducible perfu- sion parameters of hepatic parenchyma in patients af- fected by chronic liver disease. METHODS： Forty patients with chronic viral liver dis- ease, with （n = 20） or without （n = 20） cirrhosis, and 10 healthy subjects underwent CEUS and video re- cordings of each examination were then analysed with Esaote＇s Qontrast software. CEUS dedicated software Qontrast was used to determine peak （the maximum signal intensity）, time to peak （TTP）, region of blood value （RBV） proportional to the area under the time- intensity curve, mean transit time （MTT） measured in seconds and region of blood flow （RBF）. RESULTS： Qontrast-assisted CEUS parameters dis- played high inter-observer reproducibility （κ： coefficients of 0.87 for MTT and 0.90 TTP）. When the region of in-terest included a main hepatic vein, Qontrast-calculated TTP was significantly shorter in cirrhotic patients （vs non-cirrhotics and healthy subjects） （71.0 ± 11.3 s vs 82.4±15.6 s, 86.3±20.3 s, P 〈 0.05）. MTIs in the patients with liver cirrhosis were significantly shorter than those of controls （111.9±22.0 s vs 139.4±39.8 s, P 〈 0.05）, but there was no significant difference between the cirrhotic and non-cirrhotic groups （111.9± 22.0 s vs 110.3 ±14.6 s）. Peak enhancement in the patients with liver cirrhosis was also higher than that observed in controls （23.9± 5.9 vs 18.9±7.1, P = 0.05）. There were no significant intergroup differences in the RBVs and RBFs. CONCLUSION： Qontrast-assisted CEUS revealed re- producible differences in liver perfusion parameters during the development of hepatic fibrogenesis.展开更多
In this thesis,construction industries face with the major challenges are cost overruns and time delays, which have existed in most of projects, especially in developing countries. Construction projects and the enviro...In this thesis,construction industries face with the major challenges are cost overruns and time delays, which have existed in most of projects, especially in developing countries. Construction projects and the environment are increasingly complex, thus it has greater demands on project managers and cost managers that deliver processes on time. However the process of construction is limited to unforeseeable and variable factors, resulting from many sources. The aim of the report is to analyze determining factors about causing budget overrun and time delays by reviewing and identifying past cases. Furthermore, the construction process is made up of three critical phases, i.e. conception, design, construction. Generally, the majority of time delays and cost overrun happen in the period of construction, where many factors are always unforeseeable, and time delays usually associate with cost overruns. （Chan and Kumaraswamy, 1997）展开更多
A functional central limit theorem is proved for the centered occupation time process of the super α-stable processes in the finite dimensional distribution sense. For the intermediate dimensions α < d < 2α (...A functional central limit theorem is proved for the centered occupation time process of the super α-stable processes in the finite dimensional distribution sense. For the intermediate dimensions α < d < 2α (0 < α ≤ 2), the limiting process is a Gaussian process, whose covariance is specified; for the critical dimension d= 2α and higher dimensions d < 2α, the limiting process is Brownian motion.展开更多
A class of superprocesses which dies out is investigated.Under the condition of norextinction, a new superprocess is constructed,its life time is infinite, and its distribution is determined by the moment function. Se...A class of superprocesses which dies out is investigated.Under the condition of norextinction, a new superprocess is constructed,its life time is infinite, and its distribution is determined by the moment function. Several limit theorems about this superprocess and its occupation time process are obtained.展开更多
基金Supported by Associazione per la Prevenzione e Cure delle Patologie dell’Apparato Digerente-Associazione di Volontariatogrant
文摘AIM： To assess if software assisted-contrast-enhanced ultrasonography （CEUS） provides reproducible perfu- sion parameters of hepatic parenchyma in patients af- fected by chronic liver disease. METHODS： Forty patients with chronic viral liver dis- ease, with （n = 20） or without （n = 20） cirrhosis, and 10 healthy subjects underwent CEUS and video re- cordings of each examination were then analysed with Esaote＇s Qontrast software. CEUS dedicated software Qontrast was used to determine peak （the maximum signal intensity）, time to peak （TTP）, region of blood value （RBV） proportional to the area under the time- intensity curve, mean transit time （MTT） measured in seconds and region of blood flow （RBF）. RESULTS： Qontrast-assisted CEUS parameters dis- played high inter-observer reproducibility （κ： coefficients of 0.87 for MTT and 0.90 TTP）. When the region of in-terest included a main hepatic vein, Qontrast-calculated TTP was significantly shorter in cirrhotic patients （vs non-cirrhotics and healthy subjects） （71.0 ± 11.3 s vs 82.4±15.6 s, 86.3±20.3 s, P 〈 0.05）. MTIs in the patients with liver cirrhosis were significantly shorter than those of controls （111.9±22.0 s vs 139.4±39.8 s, P 〈 0.05）, but there was no significant difference between the cirrhotic and non-cirrhotic groups （111.9± 22.0 s vs 110.3 ±14.6 s）. Peak enhancement in the patients with liver cirrhosis was also higher than that observed in controls （23.9± 5.9 vs 18.9±7.1, P = 0.05）. There were no significant intergroup differences in the RBVs and RBFs. CONCLUSION： Qontrast-assisted CEUS revealed re- producible differences in liver perfusion parameters during the development of hepatic fibrogenesis.
文摘In this thesis,construction industries face with the major challenges are cost overruns and time delays, which have existed in most of projects, especially in developing countries. Construction projects and the environment are increasingly complex, thus it has greater demands on project managers and cost managers that deliver processes on time. However the process of construction is limited to unforeseeable and variable factors, resulting from many sources. The aim of the report is to analyze determining factors about causing budget overrun and time delays by reviewing and identifying past cases. Furthermore, the construction process is made up of three critical phases, i.e. conception, design, construction. Generally, the majority of time delays and cost overrun happen in the period of construction, where many factors are always unforeseeable, and time delays usually associate with cost overruns. （Chan and Kumaraswamy, 1997）
基金This work was supported by the National Natural Science Foundation of China(Grant Nos.10101005 and 10121101)the Scientific Research Foundation for the Returned Overseas Chinese Scholars,State Education Ministry.
文摘A functional central limit theorem is proved for the centered occupation time process of the super α-stable processes in the finite dimensional distribution sense. For the intermediate dimensions α < d < 2α (0 < α ≤ 2), the limiting process is a Gaussian process, whose covariance is specified; for the critical dimension d= 2α and higher dimensions d < 2α, the limiting process is Brownian motion.
文摘A class of superprocesses which dies out is investigated.Under the condition of norextinction, a new superprocess is constructed,its life time is infinite, and its distribution is determined by the moment function. Several limit theorems about this superprocess and its occupation time process are obtained.
