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重症肺超探查血液透析患者两肺B线数量与各项临床指标的相关性
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作者 孙玉宝 杜红霞 芦乙滨 《实用临床医药杂志》 CAS 2018年第9期72-74,78,共4页
目的探讨血液透析患者B线数量与各项临床参数的相关性。方法 49例长期透析的患者使用~迈瑞M7超声仪器进行肺部筛查。进行双侧前胸部和侧胸部的超声筛查并记录B线总数量。探讨B线数量与其他临床参数的相关性。结果患者心率和血浆log(NT... 目的探讨血液透析患者B线数量与各项临床参数的相关性。方法 49例长期透析的患者使用~迈瑞M7超声仪器进行肺部筛查。进行双侧前胸部和侧胸部的超声筛查并记录B线总数量。探讨B线数量与其他临床参数的相关性。结果患者心率和血浆log(NT-proBNP)水平与B线总数量呈正相关(P=0.01、0.00);体质量、血浆白蛋白水平、肌酐水平与B线数量呈负相关(P=0.02、0.00、0.01)。结论 B线数量与血浆NT-proBNP水平正相关。体质量、血浆白蛋白水平、肌酐水平与B线数量呈负相关。 展开更多
关键词 B线 重症 血液透析 白蛋白 肌酐
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大黄片治疗“超重”症500例 被引量:5
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作者 华宝芬 高雅萍 焦东海 《上海中医药杂志》 北大核心 1991年第6期32-33,共2页
临床上一般将超过标准体重20%以上者称为肥胖症。“超重”症指的是超过标准体重10%以上,但还未达到肥胖症标准。目前临床上超重症病人较多。
关键词 超重症 大黄
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BILL Strategy:Points to Consider During the Performance and Interpretation of Critical Care Echocardiography
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作者 Hong-Min Zhang Hui Lian Xiao-Ting Wang 《Chinese Medical Sciences Journal》 CAS CSCD 2024年第3期234-241,共8页
The growing utilization of critical care echocardiography(CCE) by clinicians necessitates a meticulous review of clinical conditions in critically ill patients, both before and during the examination. The reviewing pr... The growing utilization of critical care echocardiography(CCE) by clinicians necessitates a meticulous review of clinical conditions in critically ill patients, both before and during the examination. The reviewing process of clinical conditions minimizes the risk of overlooking or misinterpreting crucial findings. This article proposes a comprehensive strategy, namely BILL strategy, to integrate into the CCE protocol, where "B" represents baseline respiratory and hemodynamic support, "I" signifies information gleaned from invasive monitoring, including central venous pressure and thermodilution-derived cardiac output, the first "L" denotes laboratory results such as central venous oxygen saturation, troponin, and brain natriuretic peptide, and the second "L" refers to lung ultrasound data. Combining the BILL strategy with CCE can enhance comprehensive understanding of critical conditions, potentially leading to improved diagnostic accuracy and patient outcomes. 展开更多
关键词 ECHOCARDIOGRAPHY critical care clinical condition
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瘦身守住五个关键时刻
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《大观周刊》 2006年第7期18-18,共1页
人在一天中有5个时刻是最想吃东西的,这种时候,如何选择非常重要,如果放纵自己的食欲,久而久之,肥胖、超重等症状就会在你不经意间找上门来。这个5个时刻分别是:
关键词 瘦身 食欲 肥胖 超重症
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Prevalence of overweightedness in patients with gastro-esophageal reflux 被引量:7
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作者 Luca Piretta Federico Alghisi +1 位作者 Fiorella Anzini Enrico Corazziari 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第34期4602-4605,共4页
AIM: To evaluate whether the prevalence of overweight and obese conditions is increased in gastro-esophageal reflux disease (GERD) patients (with 24-h pathological pH recordings) in comparison to general population. M... AIM: To evaluate whether the prevalence of overweight and obese conditions is increased in gastro-esophageal reflux disease (GERD) patients (with 24-h pathological pH recordings) in comparison to general population. METHODS: A total of 196 consecutive patients (103 females, age range 18-83 years) with symptoms of gastro-esophageal reflux (GER) and 24-h pathological esophageal pH-metry. Body mass index (BMI) of the patients was calculated and its distribution (%) was compared with that of the Italian general population as assessed by National Bureau of Census (ISTAT). To evaluate the association of GERD with weight categories, the binomial test was employed. P < 0.05 was considered statistically significant. RESULTS: In males, overweightedness (BMI 25-25.9) was present in 43% of GERD patients vs 41.8% of Italian population (IP) (ns), obesity (BMI ≥ 30) in 10.9% vs 9.1% (ns). In females overweight was present in 34.9% of GERD patients vs 25.7% of IP (P < 0.01), obesity in 13.6% of GERD patients vs 9.1% of IP (P < 0.01). No statistically significant differences were noted in different age classes. CONCLUSION: In comparison to the Italian general population, the prevalence of overweightedness and obesity is increased in female but not in male patients with ascertained gastro-esophageal reflux disease. 展开更多
关键词 Gastro-esophageal reflux OBESITY OVERWEIGHT 24-h pH-metry Body mass index
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Effect of Focused Cardiac Ultrasound in Combination with Lung Ultrasound on Critically Ill Patients: A Multicenter Observational Study in China 被引量:1
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作者 Hongmin Zhang Lina Zhang +9 位作者 Lixia Liu Ying Zhu Wanhong Yin Wei He Xiuling Shang Yangong Chao Liwen Lv Xiaoting Wang Dawei Liu 《Chinese Medical Sciences Journal》 CAS CSCD 2021年第4期257-264,共8页
Objective Focused cardiac ultrasound(FCU)and lung ultrasound(LU)are increasingly being used in critically ill patients.This study aimed to investigate the effect of FCU in combination with LU on these patients and to ... Objective Focused cardiac ultrasound(FCU)and lung ultrasound(LU)are increasingly being used in critically ill patients.This study aimed to investigate the effect of FCU in combination with LU on these patients and to determine if the timing of ultrasound examination was associated with treatment change.Methods This is a multicenter cross-sectional observational study.Consecutive patients admitted to the intensive care unit(ICU)were screened for enrollment.FCU and LU were performed within the first 24 h,and treatment change was proposed by the performer based on the ultrasound results and other clinical conditions.Results Among the 992 patients included,502 were examined within 6 h of ICU admission(early phase group),and 490 were examined after 6 h of admission(later phase group).The early phase group and the later phase group had similar proportions of treatment change(48.8%vs.49.0%,χ^(2)=0.003,P=0.956).In the multivariable analysis,admission for respiratory failure was an independent variable associated with treatment change,with an odds ratio(OR)of 2.357[95%confidence interval(CI):1.284-4.326,P=0.006];the timing of examination was not associated with treatment change(OR=0.725,95%CI:0.407-1.291,P=0.275).Conclusions FCU in combination with LU,whether performed during the early phase or later phase,had a significant impact on the treatment of critically ill patients.Patients with respiratory failure were more likely to experience treatment change after the ultrasound examination. 展开更多
关键词 cardiac ultrasound lung ultrasound critically ill POINT-OF-CARE
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Body mass index does not affect the survival of pancreatic cancer patients 被引量:6
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作者 Qing-long Jiang Cheng-feng Wang +11 位作者 Yan-tao tian Huang Huang Shui-Sheng Zhang Dong-bing Zhao Jie Ma Wei Yuan Yue-Min Sun Xu Che Jian-Wei Zhang Yun-Mian Chu Ya-Wei Zhang Ying-tai Chen 《World Journal of Gastroenterology》 SCIE CAS 2017年第34期6287-6293,共7页
AIM to evaluate the association of body mass index(b MI) with the overall survival of pancreatic ductal adenocarcinoma(PDAC) patients.METHODS A retrospective analysis of PDAC patients diagnosed in the National Cancer ... AIM to evaluate the association of body mass index(b MI) with the overall survival of pancreatic ductal adenocarcinoma(PDAC) patients.METHODS A retrospective analysis of PDAC patients diagnosed in the National Cancer Center of China between January 1999 and December 2014 was performed. these patients were categorized into four b MI groups(< 18.5, 18.5-22.9, 23-27.4 and ≥ 27.5 kg/m2). χ2 tests for comparison of the proportions of categorical variables, and Student's t-test or Mann-Whitney test for continuous variables were employed. Survival analysis was performed with the Kaplan-Meyer method. their HRs of mortality and 95%CIs were estimated using the Cox proportional hazards model.RESULTS With a median age of 59.6 years(range: 22.5-84.6 years), in total 1783 PDAC patients were enrolled in this study. their mean usual b MI was 24.19 ± 3.53 for the whole cohort. More than half of the patients(59.3%) experienced weight loss during the disease onset and progression. Compared with healthy-weight individuals, newly diagnosed patients who were overweight or obese had more severe weight loss during their disease onset and progression(P < 0.001). Individuals who were overweight or obese were associated with positive smoking history(P < 0.001). A significant difference in comorbidity of diabetes(P = 0.044) and coronary artery disease(P < 0.001) was identified between high b MI and normal-weight patients. After a median follow-up of 8 mo, the survival analysis showed no association between b MI and the overall survival(P = 0.90, n = 1783). When we stratified the whole cohort by pancreatic cancer stage, no statistically significant association between b MI and overall survival was found for resectable(P = 0.99, n = 217), unresectable locally advanced(P = 0.90, n = 316) and metastatic patients(P = 0.88, n = 1250), respectively. the results did not change when we used the b MI at diagnosis.CONCLUSION Our results showed no significance of b MI for the overall survival of PDAC patients. 展开更多
关键词 body mass index Pancreatic cancer OVERWEIGHT Smoking history Survival analysis
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儿科日间手术中超重(或肥胖症)与胃液特性的关系:在禁食指南和误吸风险评估方面的意义
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作者 Scott D. Cook-Sather Paul R. Gallagher +11 位作者 Lydia E. Kruge Jonathan M. Beus Brian P. Ciampa Kevin Conor Welch Sina Shah-Hosseini Jieun S. Choi Reshma Pachikara Kim Minger Ronald S. Litman Mark S. Schreiner 周洁(译) 李士通(校) 《麻醉与镇痛》 2010年第6期38-49,共12页
背景超重或肥胖的日间手术儿科患者手术前2小时禁水的安全性尚未得到证实。健康的儿童和肥胖的成人在手术前禁水2小时后残留胃液量(GFVs)并不多,因此认为误吸风险并不高。因此我们将测算日间手术患者中超重症或肥胖症的患病率,并假... 背景超重或肥胖的日间手术儿科患者手术前2小时禁水的安全性尚未得到证实。健康的儿童和肥胖的成人在手术前禁水2小时后残留胃液量(GFVs)并不多,因此认为误吸风险并不高。因此我们将测算日间手术患者中超重症或肥胖症的患病率,并假设不管是体重指数还是禁食时间均不会对GFV或胃液pH值产生显著的影响。所有受试儿童均于手术前禁清水2小时,并假设超重或肥胖患儿的GFV不会多于偏瘦或正常体重患儿,而呕吐或误吸的风险也很低。方法本研究中连续纳入了1000例2-12岁行日间手术的患儿,记录人口统计学资料、病史、身高和体重。另外纳入1000例需全麻插管的日间手术患儿(2。12岁)进行研究。气管插管后,经口插入一根14—18F的胃管,抽空胃内容物。用药情况、禁食时间、GFV、pH值和呕吐事件均被详细记录。采用疾病预防及控制中心的生长图表(2000)评定理想体重(IBW=第50个百分位数),并对患儿进行分层:偏瘦或正常体重(BMI在第25—75个百分位数)、超重(第95个百分位数〈BMI≥第85个百分位数)、肥胖(BMI≥第95个百分位数)。结果在所有的日间手术患儿中有14%属于超重,13.3%属于肥胖。肥胖儿按公斤体重算出的GFV较低(P〈0.001)。当我们用IBW进行校正后,所有BMI组中GFV(mw校正后)的容量都相等(均值为0.96ml/kg,SD为0.71;中位数为0.86ml/kg,IQR为0.96)。手术前使用对乙酰氨基酚和咪达唑仑均导致GFV(1BW校正后)增加(P=0.025和P=0.001)。而ASA11I级(P=0.024)、男性(P=0.012)、胃食管反流性疾病(P=0.049)和使用质子泵抑制剂(P=0.018)患儿的GFV(mw校正后)较低。GFV(IBw校正后)与禁食时间和年龄无关。胃液酸度较低与年龄较小(P=0.005)、BMI较高(P=0.036)和美国非洲裔(P=0.033)患儿等因素相关。有8例患儿在全麻诱导时发生了呕吐(其中50%有肥胖症,P=0.052,75%患有阻塞性睡眠呼吸暂停症,P=0.061)。呕吐与ASA分级较高有关,但却与禁食时间的长短无关。研究中没有出现误吸事件。结论27%的儿科日闻手术患儿属超重或肥胖儿童。无论进食时间长短或BMI如何,GFV(IBw校正后)均为1ml/kg,因此这些患儿均可以在手术前2小时饮清水。在此研究群体中,罕见的呕吐事件与禁食时间的缩短并无相关性。 展开更多
关键词 禁食时间 儿科患者 风险评估 肥胖症 超重症 胃液量 误吸 阻塞性睡眠呼吸暂停症
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Clodronate-superparamagnetic iron oxide-containing liposomes attenuate renal injury in rats with severe acute pancreatitis 被引量:2
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作者 Sheng-chun DANG Yan-hua ZENG +8 位作者 Ping-jiang WANG Bao-ding CHEN Rong-fang CHEN Arun KUMAR SINGH Pankaj KUMAR Shu FENG Lei CUI Hao WANG Jian-xin ZHANG 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2014年第6期556-565,共10页
Background and objective: It has been shown that macrophages play an important role in the development of severe acute pancreatitis (SAP), and eventually lead to multiple organ failure (MOF). Clodronate-liposome ... Background and objective: It has been shown that macrophages play an important role in the development of severe acute pancreatitis (SAP), and eventually lead to multiple organ failure (MOF). Clodronate-liposome selectively depleted macrophages. This study was to investigate the role of renal macrophage infiltration in acute renal injury in rats with SAP and to evaluate the potential of superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance imaging (MRI) for diagnosis. Methods: Superparamagnetic Fe3O4 nanoparticles were prepared by chemical coprecipitation. SPIO-liposomes and SPIO-clodronate-liposomes were prepared by the thin film method. SAP models were prepared by injection of sodium taurocholate into the subcapsular space of rat pancreas. Sprague-Dawley rats were randomly divided into a control group, SAP plus SPIO-liposome (P) group, and SAP plus SPIO-clodronatecontaining liposome (T) group. Kidney injury was evaluated by T2-weighted MRI scan. The levels of serum amylase (SAM), blood urea nitrogen (BUN), and serum creatinine (SCr) were measured by an automated enzymatic method. Serum tumor necrosis factor-α (TNF-α) was measured by enzyme-linked immunosorbent assay (ELISA). Pathological changes in the pancreas and kidney were observed using hematoxylin and eosin (H&E) staining, while cell apoptosis was detected with terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining. In addition, the macrophage markers (CD68) of the renal tissue were detected with immunohistochemistry. Results: The pathological changes in the pancreas and kidneys of rats in the T group were milder than those in the P group. The MRI signal intensity of the kidneys in the P and T groups was significantly lower than that in the control group. There were significant changes in the two experimental groups (P〈0.01). The levels of SAM, Bun, SCr, and TNF-α in rats in the P group were higher than those in the control group (P〈0.01) and in the T group (P〈0.01). The apoptosis of the kidney in the T group was higher than that in the P group at 2 and 6 h (P〈0.01). Conclusions: Clodronate-containing liposomes protected against renal injury in SAP rats, and SPIO can be used as a tracer for MRI examination to detect renal injury in SAP rats. SPIO-aided MRI provided an efficient non-invasive way to monitor the migration of macrophages after renal injury in rats with SAP. 展开更多
关键词 PANCREATITIS Clodronate disodium MACROPHAGE Kidney injury
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