目的:通过网状Meta分析法对比不同运动措施对超重肥胖女性健康体适能的干预效果,为超重肥胖女性选择科学、有效的运动方式提供更为全面的理论依据和实践参考。方法:检索外文数据库Web of science、Pubmed、The Cochrane Library、Embase...目的:通过网状Meta分析法对比不同运动措施对超重肥胖女性健康体适能的干预效果,为超重肥胖女性选择科学、有效的运动方式提供更为全面的理论依据和实践参考。方法:检索外文数据库Web of science、Pubmed、The Cochrane Library、Embase、Scopus、EBSCO等及中文数据库中国万方、维普自建库至2021年11月4日的中文及外文文献。由2位研究人员分别采用独立双盲的方式,按照纳入与排除标准筛选文献。采用Review Manager5.4.1偏倚风险评估工具,对已纳入的研究进行文献质量评价与偏倚风险评估。采用Stata17.0软件进行相应数据分析和作图。结果:网状Meta分析结果显示:与对照组相比,有氧运动干预[ES=-1.07,95%CI(-2.07,-0.07)]、有氧联合抗阻运动干预[ES=-1.49,95%CI(-2.78,-0.21)],均可显著改善其身体成分;有氧联合抗阻运动干预[ES=1.42,95%CI(0.29,2.54)],可显著提高心肺适能;抗阻运动干预[ES=1.68,95%CI(0.12,3.24)],可增强肌肉适能;有氧运动干预[ES=3.73,95%CI(3.04,4.43)]、有氧联合抗阻运动干预[ES=5.24,95%CI(3.23,7.26)],均可增加柔韧性。SUCRA概率排序结果显示,有氧联合抗阻运动对于改善身体成分指标(SUCRA=77.4)、心肺适能指标(SUCRA=84.5)、柔韧性指标(SUCRA=95.7)起最显著作用,抗阻运动对于改善肌肉适能指标(SUCRA=84.5)起最显著作用。结论:有氧联合抗阻运动可能是改善身体成分、心肺适能和柔韧性的最佳运动方式,抗阻运动可能是增强肌肉适能的最佳运动方式。受纳入研究数量和质量的限制,上述结论存在一定局限性,尚需开展更多高质量研究予以验证。展开更多
Background： The aim of this study was to compare 6 weeks short-term moderate intensity aerobic exercise and dieting on serum metabolomics and cardio-metabolic risk factors in pre-menopausal women. Methods： Ninety pr...Background： The aim of this study was to compare 6 weeks short-term moderate intensity aerobic exercise and dieting on serum metabolomics and cardio-metabolic risk factors in pre-menopausal women. Methods： Ninety previously inactive overweight and obese （BMI 25-35 kg/m2） women （age 41.5 ± 7.6 years） were randomized to either a 6-week Nordic walking exercise program （EX, n = 45） or dietary counseling group （DI, n = 45）. Body composition, serum glucose, insulin and lipids were measured. Serum low-molecular-weight metabolites and lipid constituents were analyzed by nuclear magnetic resonance spectroscopy. Measurements were done at baseline and 7 days after the last training session. Results： Six weeks aerobic exercise program yielded reductions in serum free fatty acids （-34.7%, 95% confidence interval （CI）, -50 to -18, p 〈 0.001）, glucose （-9.6%, 95%CI, -15 to -4, p 〈 0.001） and homeostasis model assessment of insulin resistance （HOMA-IR） （-28.7%, 95%CI, -48 to -10, p = 0.005） without changes in body weight or fat mass. Diet counseling resulted in loss of body weight （1.5%, 95%CI, -2.3 to -0.7, p = 0.001） but no changes in free fatty acids, fasting glucose, or HOMA-IR were found. Conclusion： Our results indicate that small weight loss does not produce measurable health benefits, whereas short-term regular aerobic exercise can improve glucose and lipid metabolism even in the absence of weight loss in previously sedentary overweight and obese women.展开更多
基金supported by Suunto Oy(Grant 28.5.2009)University of Jyvaskyla Wellness program+1 种基金the Shanghai Overseas Distinguished Professor Award Program 2013the Chinese Ministry of Science and Technology,China National Science and Technology Infrastructure Program 2012(Grant 2012BAK21B03-4)
文摘Background： The aim of this study was to compare 6 weeks short-term moderate intensity aerobic exercise and dieting on serum metabolomics and cardio-metabolic risk factors in pre-menopausal women. Methods： Ninety previously inactive overweight and obese （BMI 25-35 kg/m2） women （age 41.5 ± 7.6 years） were randomized to either a 6-week Nordic walking exercise program （EX, n = 45） or dietary counseling group （DI, n = 45）. Body composition, serum glucose, insulin and lipids were measured. Serum low-molecular-weight metabolites and lipid constituents were analyzed by nuclear magnetic resonance spectroscopy. Measurements were done at baseline and 7 days after the last training session. Results： Six weeks aerobic exercise program yielded reductions in serum free fatty acids （-34.7%, 95% confidence interval （CI）, -50 to -18, p 〈 0.001）, glucose （-9.6%, 95%CI, -15 to -4, p 〈 0.001） and homeostasis model assessment of insulin resistance （HOMA-IR） （-28.7%, 95%CI, -48 to -10, p = 0.005） without changes in body weight or fat mass. Diet counseling resulted in loss of body weight （1.5%, 95%CI, -2.3 to -0.7, p = 0.001） but no changes in free fatty acids, fasting glucose, or HOMA-IR were found. Conclusion： Our results indicate that small weight loss does not produce measurable health benefits, whereas short-term regular aerobic exercise can improve glucose and lipid metabolism even in the absence of weight loss in previously sedentary overweight and obese women.
