从逻辑与历史相统一中把握“四史”学习——论次序感、趋势感与共时感

“四史”是指导我国未来实践的理论宝库,学习“四史”有重要意义。要学好“四史”,就必须有学习“四史”的正确态度。逻辑与历史相统一作为马克思研究政治经济学时所使用的科学方法论,并不是简单的逻辑与历史相一致,而是建立在次序感、趋势感和共时感基础之上的逻辑感与历史感的三重统一。通过深入分析以三重历史感为基础的逻辑与历史相统一,可以帮助大家树立对待历史的正确态度,更有效地学习“四史”,并汲取其中的理论营养。

Trends in the eradication rates of Helicobacter pylori infection for eleven years

AIM:To evaluate the trends in the eradication rate of Helicobacter pylori(H.pylori) over the past 11 years in a single center.METHODS:This retrospective study covered the period from January 2000 to December 2010.We evaluated 5746 patients diagnosed with gastric ulcers(GU),duodenal ulcers(DU),GU + DU,or nonpeptic ulcers associated with an H.pylori infection.We treated them annually with the 2 wk standard first-line triple regimen,proton pump inhibitor(PPI) + amoxicilin + clarithromycin(PAC;PPI,clarithromycin 500 mg,and amoxicillin 1 g,all twice a day).The follow-up test was performed at least 4 wk after the completion of the 2 wk standard H.pylori eradication using the PAC regimen.We also assessed the eradication rates of 1 wk second-line therapy with a quadruple standard regimen(PPI b.i.d.,tripotassium dicitrate bismuthate 300 mg q.i.d.,metronidazole 500 mg t.i.d.,and tetracycline 500 mg q.i.d.) after the failure of the first-line therapy.Statistical analysis was performed with 95%CI for the differences in the annual eradication rates.RESULTS:A total of 5746 patients [2333 males(58.8%),1636 females(41.2%);mean age of males vs females 51.31 ± 13.1 years vs 52.76 ± 13.6 years,P < 0.05,total mean age 51.9 ± 13.3 years(mean ± SD)] were investigated.Among these patients,1674 patients were excluded:35 patients refused treatment;18 patients ceased H.pylori eradication due to side effects;1211 patients had inappropriate indications for H.pylori eradication,having undergone stomach cancer operation or chemotherapy;and 410 patients did not undergo the follow-up.We also excluded 103 patients who wanted to stop eradication treatment after only 1 wk due to poor compliance or the side effects mentioned above.Finally,we evaluated the annual eradication success rates in a total of 3969 patients who received 2 wk first-line PAC therapy.The endoscopic and clinical findings in patients who received the 2 wk PAC were as follows:gastric ulcer in 855(21.5%);duodenal ulcer in 878(22.1%);gastric and duodenal ulcer in 124(3.1%),erosive,atrophic gastritis and functional dyspepsia in 2055(51.8%);and other findings(e.g.,MALToma,patients who wanted to receive the therapy even though they had no abnormal endoscopic finding) in 57(0.5%).The overall eradication rate of the 2 wk standard firstline triple regimen was 86.5%.The annual eradication rates from 2000 to 2010 were 86.7%,85.4%,86.5%,83.3%,89.9%,90.5%,88.4%,84.5%,89.1%,85.8%,and 88.3%,sequentially(P = 0.06).No definite evidence of a significant change in the eradication rate was seen during the past eleven years.The eradication rates of second-line therapy were 88.9%,82.4%,85%,83.9%,77.3%,85.7%,84.4%,87.3%,83.3%,88.9%,and 84%(P = 0.77).The overall eradication rate of 1 wk quadruple second-line therapy was 84.7%.There was no significant difference in the eradication rate according to the H.pylori associated diseases.CONCLUSION:This study showed that there was no trend change in the H.pylori eradication rate over the most recent 11 years in our institution.

网感表达:主流媒体的创新趋势--以央视融媒体实践为例

媒体融合背景下,主流媒体在内容生产领域的创新发展进行了多样的探索,其中"网红"新闻主播、互联网用语的活用、轻松有趣的叙事手法使主流媒体的新闻报道以全新的魅力吸引受众,引发关注和热议。本文着眼于主流媒体在融媒体场域下创新发展的路径探索中所呈现的网感表达趋势,从主流媒体网感表达趋势实践分析、主流媒体网感表达趋势原因探索以及主流媒体网感表达趋势前景展望三个层次逐步推进,由表及里,分析主流媒体内容生产领域中的网感表达趋势。

液压控制技术在筑路机械中的应用

工程建设技术的发展促进了液压控制技术在工程机械的广泛应用,在目前液压控制技术已经取得了一定的成绩,但是随着科技的发展,正在逐渐趋向智能化与自动化,其中负荷传感液压控制系统因为它在很多方面的优势在工程机械已广泛得以普及,根据作者自己的工作和学习经验,阐述了工程机械液压控制技术的研究进展和发展趋势,并简述工程机械液压控制技术被广泛应用于负荷传感液压控制系统的现状。

Hepatitis B and C infection and liver disease trends among human immunodeficiency virus-infected individuals

AIM:To examine trends in and correlates of liver disease and viral hepatitis in an human immunodeficiency virus (HIV)-infected cohort. METHODS:The multi-site adult/adolescent spectrum of HIV-related diseases (ASD) followed 29 490 HIVinfected individuals receiving medical care in 11 U.S. metropolitan areas for an average of 2.4 years,and a total of 69 487 person-years,between 1998 and 2004. ASD collected data on the presentation,treatment,and outcomes of HIV,including liver disease,hepatitis screening,and hepatitis diagnoses. RESULTS:Incident liver disease,chronic hepatitis B virus (HBV),and hepatitis C virus (HCV) were diagnosed in 0.9,1.8,and 4.7 per 100 person-years. HBV and HCV screening increased from fewer than 20% to over 60% during this period of observation (P < 0.001). Deaths occurred in 57% of those diagnosed with liver disease relative to 15% overall (P < 0.001). Overall 10% of deaths occurred among individuals with a diagnosis of liver disease. Despite care guidelines promoting screening and vaccination for HBV and screening for HCV,screening and vaccination were not universally conducted or,if conducted,not documented. CONCLUSION:Due to high rates of incident liver disease,viral hepatitis screening,vaccination,and treatment among HIV-infected individuals should be a priority.

Reliable Analytic Strategy to Correlate the Morphological and Cytological Parameters on Lupinus termis L, against Fusarium oxysporum Infection

Many analytic strategies have emerged to estimate plant responses to Fusarium wilt. The demand for fast and reliable method （diagnosis, prediction） to determine isolate strength accurately is not established yet. Early determination of pathogen strength helps in plant medication. The aim of this study was to develop a faster strategy and method for early determination of fungal isolates strength in correlation to plant response. Till now, the scientists have no consensus on the most correlated parameters that could express wilt precisely. In this study, 30 isolates of Fusarium oxysporum isolated from Lupinus termis L. were used to provide an explicit image about the real strength of Fusarium isolates and its impact on the plant. Wilting percentage ranged from 26.67% to 93.33% of the infected plants depending on isolate virulence. Some of cellular, morphological and physical measurements were conducted on 8 out of 30 isolates, including root （length, fresh weight （FW） and dry weight （DW））, nodules （water content （WC）, FW, DW）, stem （height, WC, FW, DW）, total leaves/plant （WC, FW, DW） and the fourth leaf （WC, FW, DW, leaf area, epidermal cell area, epidermal cell number, succulence）. Hierarchical clustering was used to determine the variance between the isolates. Detrended correspondence analysis （DCA） and canonical correspondence analysis （CCA） were used to determine the most important growth parameters that could express wilting accurately. The CCA results showed that most of the measured parameters on the fourth leaf, except for leaf epidermal cell number, were highly and positively correlated to wilt. That makes these specific parameters valuable and sensitive for any changes in isolates strength. Accordingly, a mathematical model was created to be helpful in the quick determination of isolate strength and precise medication.

High-altitude tree growth responses to climate change across the Hindu Kush Himalaya

Aims Rapid warming at high altitudes may lead to a higher sensitivity in tree growth to temperature.The key factors constraining tree radial growth and to what extent regional tree growth has suffered from climatic changes are unclear.Methods Tree-ring width data were collected from 73 sites across the Hindu Kush Himalaya(HKH),including three dominant genera(Abies,Juniperus and Picea)at high altitudes over 3000 m.Dynamic time warping was introduced to develop subregional chronologies by considering the synchrony of annual tree growth among different sites.We quantified the contribution of the climate variables,and analyzed the spatiotemporal variation of the growth–climate relationship.Important Findings The site chronologies were grouped into three clusters,corresponding to the three distinct bioclimatic zones,i.e.the western HKH,central-eastern HKH and southeastern Tibetan Plateau(TP).Tree growth was positively correlated to winter and spring precipitation in the drier western HKH,and to winter temperature and spring precipitation in the humid southeastern TP.Tree growth was markedly constrained by the minimum temperature,especially in winter,with its importance increasing from the west toward the east.As shown by moving correlation analysis,the signal of winter temperature in tree growth was weakened in the western and central-eastern HKH,while it was enhanced in the southeastern TP following rapid warming since the 1980s.Our results highlight that continuous warming may cause forest recession due to warming-induced moisture deficit in the western HKH,but forest expansion in the southeastern TP.

BED-CEIA估计HIV-1新近感染率的有效性及其影响因素的评价

在艾滋病流行病学研究中,衡量艾滋病流行趋势最常用的指标是HIV累积感染率和新近感染率.与累积感染率相比,新近感染率对艾滋病流行趋势预测、干预效果评价以及防制策略的制定等能提供更直接的信息.在获取新近感染率的方法中,除了经典的流行病学队列随访方法,目前普遍使用的血清学方法之一是IgG捕获BED酶联免疫法（BED-CEIA）.2001年,美国疾病预防控制中心（CDC）艾滋病免疫和诊断室评估了16种基于不同抗体和原理的HIV-1新近感染检测方法,发现新近感染者与既往感染者相比,各种抗体滴度均较低;其中gp41抗体滴度在新近感染者和既往感染者中的差别最大,两者的滴度区间几乎没有重叠,新近感染者的gp41抗体亲和力低于既往感染者,从而认为gp41抗体能够区分新近感染者和既往感染者,并且酶联免疫实验操作相对简单、效果也较理想,因此该室着手开发基于gp41抗体的HIV-1新近感染检测的酶联免疫方法[1].