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大鼠脑缺血再灌注损伤血清IL-8和中性粒细胞趋化指数的变化 被引量:2
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作者 刘士福 《放射免疫学杂志》 CAS 2006年第2期116-118,共3页
目的:探讨了血清IL-8和中性粒细胞趋化指数测定在脑缺血再灌注损伤中的变化。方法:采用改良Zealonga线栓法大鼠大脑中动脉闭塞(middlecerebralarteryocclusion,MCAO)模型,将大脑中动脉(MCA)先行闭塞2h,然后进行灌注不同的时间。应用免... 目的:探讨了血清IL-8和中性粒细胞趋化指数测定在脑缺血再灌注损伤中的变化。方法:采用改良Zealonga线栓法大鼠大脑中动脉闭塞(middlecerebralarteryocclusion,MCAO)模型,将大脑中动脉(MCA)先行闭塞2h,然后进行灌注不同的时间。应用免疫法测定实验组和对照组血浆中性粒细胞趋化指数,ELISA法测定IL-8。结果:血浆中性粒细胞趋化指数和IL-8于再灌注1h最高,随后缓慢下降,再灌注48h降至正常组水平。结论:中性粒细胞参与了脑组织的正常代谢及生理功能,又参与了脑缺血再灌注损伤的病理生理过程。 展开更多
关键词 大鼠 脑缺血再灌注 中性粒细胞趋化指数 白细胞介素-8
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肝硬化患者中性粒细胞趋化性测定 被引量:1
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作者 何浩明 田小平 +2 位作者 苏彩女 庄惠琴 徐凤英 《蚌埠医学院学报》 CAS 1999年第3期192-192,共1页
目的:探讨肝硬化患者中性粒细胞功能。方法:采用琼脂糖凝胶玻板法,对34例肝硬化患者进行中性粒细胞趋化功能测定。结果:肝硬化患者中性粒细胞趋化指数低于正常人(P<0.01);但肝硬化患者血清趋化指数与正常人血清的趋化指... 目的:探讨肝硬化患者中性粒细胞功能。方法:采用琼脂糖凝胶玻板法,对34例肝硬化患者进行中性粒细胞趋化功能测定。结果:肝硬化患者中性粒细胞趋化指数低于正常人(P<0.01);但肝硬化患者血清趋化指数与正常人血清的趋化指数差异无显著性(P>0.05),说明患者血清对中性粒细胞并无趋化因子活性。结论:体外测定中性粒细胞功能,对肝硬化患者的免疫病理研究具有一定的临床价值。 展开更多
关键词 肝硬化 中性粒细胞 趋化指数 血清诊断
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山莨菪碱(654—2)对白细胞计数及趋化性的影响(简报)
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作者 陈祥银 严仪昭 +3 位作者 西品香 张宏 曾卫东 张宝玲 《中国医学科学院学报》 CAS 1987年第2期146-146,共1页
为探讨山茛菪碱(654-2)的肾上腺糖皮质激素样作用,本文观察654-2对外周血白细胞(WBC)计数及中性粒细胞趋化性的影响并与氢化考的松作用进行比较。由大鼠尾巴取血,常规计数WBC,用琼脂糖板法测定中性粒细胞(PMN)趋化性。由兔动脉取血分离P... 为探讨山茛菪碱(654-2)的肾上腺糖皮质激素样作用,本文观察654-2对外周血白细胞(WBC)计数及中性粒细胞趋化性的影响并与氢化考的松作用进行比较。由大鼠尾巴取血,常规计数WBC,用琼脂糖板法测定中性粒细胞(PMN)趋化性。由兔动脉取血分离PMN(纯度>90%)。制成2.5×10~7/ml细胞悬液,分别与不同剂量654-2温育15min。以经Zymosan激活的大鼠血清作趋化因子进行测定。初步结果表明:①给大鼠肌肉注入654-2(4mg/kg体重,共两次,间隔一小时)后4~5小时。 展开更多
关键词 氢化 WBC 性粒细胞 趋化指数 趋化 趋化作用 PMN
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慢性乙型肝炎患者中性粒细胞功能与脂质过氧化损伤的关系 被引量:1
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作者 钱月琴 孙业富 《检验医学与临床》 CAS 2013年第1期60-60,62,共2页
目的探讨慢性乙型肝炎患者中性粒细胞趋化功能与脂质过氧化的关系。方法应用琼脂糖淀胶玻片法和化学比色法对102例慢性乙型肝炎患者进行中性粒细胞趋化功能测定和超氧化物歧化酶(SOD)、丙二醛(MDA)水平检测,并与35例健康人作比较。结果... 目的探讨慢性乙型肝炎患者中性粒细胞趋化功能与脂质过氧化的关系。方法应用琼脂糖淀胶玻片法和化学比色法对102例慢性乙型肝炎患者进行中性粒细胞趋化功能测定和超氧化物歧化酶(SOD)、丙二醛(MDA)水平检测,并与35例健康人作比较。结果各型慢性乙型肝炎患者趋化指数和SOD水平均低于健康对照组(P<0.01),而MDA水平高于健康对照组(P<0.01),血清SOD水平与MDA水平呈显著负相关(r=-0.468 4,P<0.01),结论慢性乙型肝炎患者中性粒细胞趋化功能的降低与脂质过氧化有一定的相关性。 展开更多
关键词 慢性乙型肝炎 中性粒细胞 趋化指数 超氧化物歧化酶 丙二醛 脂质过氧化
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Chemical Property Variation Trend Analysis and Quality Evaluation of Water in Wei River
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作者 邱小香 卢爱刚 《Agricultural Science & Technology》 CAS 2015年第11期2555-2559,共5页
[Objective] Water quality variation trend of Wei River was analyzed and the water quality evaluation was performed in this study. [Method] Stationing and water sampling were conducted along Wei River at three differen... [Objective] Water quality variation trend of Wei River was analyzed and the water quality evaluation was performed in this study. [Method] Stationing and water sampling were conducted along Wei River at three different sites during the 12 months from January to December of 2014, the water samples were pre-treated and analyzed on chemical pollution indexes with the national standard, water quality data of Wei River in the 12 months was processed with periodic time series method, Spearman rank correlation coefficient was adopted to test pollution changing trend, and water quality status of Wei water was evaluated with integrated index of organic pollution. [Result] NH3-N and TN of Wei River exceeded the standard's lim- its; [ Y~ [ 〉Wp=0.506, [ Yss~ [ 〉Wp=0.506 and [ Y&=0~,, Diecqieo 〉Wp=0.506 indicated that the integrated index of organic pollution of Shawangdu section, S.huyuan section and Tongguan Diaoqiao section showed a significant downtrend, respetively; and the water quality of the three sections became better, and it was worth noting that it was necessary to strengthen the water quality control of Wei River from January to June, so as to ensure that the water quality of Wei River reached the standard all the time. [Cendasien] This research was of significance in improving water ecological environment in Weinan as well as rationally utilizing water resources and finally realizing permanent development. Key words Wei River; Water quality variation trend; Integrated index of organic pollution; Evaluation 展开更多
关键词 Wei River Water-quality variation trend Integrated index of organicpollution EVALUATION
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Characteristics of Spatial and Temporal Vegetation Index Variability and Its Responses to Temperature and Precipitation in Mongolia
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作者 YANG Meihuan LI Yawen +6 位作者 WANG Tao WANG Juanle LI Pengfei LI Ting HUANG Jing Ochir ALTANSUKH Davaadorj DAVAASUREN 《Journal of Resources and Ecology》 CSCD 2024年第5期1175-1184,共10页
The Mongolian Plateau,a vital ecological barrier in northern China,is of great importance for studying vegetation dynamics in Mongolia against the background of climate warming.Such studies can enhance our understandi... The Mongolian Plateau,a vital ecological barrier in northern China,is of great importance for studying vegetation dynamics in Mongolia against the background of climate warming.Such studies can enhance our understanding of regional vegetation responses to global warming and contribute to the establishment of a stronger ecological barrier in northern China.Here,we analyzed the spatial and temporal characteristics of the NDVI(normalized difference vegetation index)in Mongolia using 8 km resolution GIMMS NDVI3g data from 1990 to 2022,along with temperature,precipitation,and elevation data.Trend analysis and correlation methods were used to examine the relationships between the NDVI and temperature,as well as precipitation.The results showed four important aspects of these relationships.(1)The NDVI in Mongolia increased significantly from 1990 to 2022 at a rate of 0.0015 yr^(-1)(P<0.05).(2)Mongolia’s NDVI increased from 1990 to 2022 in 60.73%of the country.Of this total,the area with a significant increase accounted for 31.67%and was concentrated on the eastern and western edges.The area experiencing a significant decrease accounted for 15.67%and was mainly located on the southwestern edges.(3)The NDVI analysis revealed significant increasing trends in all regions except for those at elevations of 1500-2000 m.The greatest rate of increase was observed between 500 and 1000 m,and the increasing trend weakened as elevation continued to increase before gradually becoming significant again.Additionally,the NDVI increased significantly across different slopes,and the rate of increase decreased as the slope increased.(4)From 1990 to 2022,Mongolia’s NDVI was mostly negatively correlated with temperature.This occurred over 66.75%of the total land area,with 17.21%of the region exhibiting a significant negative correlation,mainly in the southwest.Conversely,the NDVI demonstrated a positive correlation with precipitation,encompassing 86.71%of the total land area.Approximately 40.44%of the region had a significant positive correlation,primarily in the southwest.In conclusion,throughout the experimental period,the vegetation state in Mongolia improved.However,due to the warming and drying climate,more attention should be paid to vegetation degradation in the south-central region. 展开更多
关键词 normalized difference vegetation index SLOPE ELEVATION trend analysis correlation analysis Mongolia
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Characterizing the Spatio-temporal Dynamics and Variability in Climate Extremes over the Tibetan Plateau during 1960–2012 被引量:15
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作者 ZHOU Yuke 《Journal of Resources and Ecology》 CSCD 2019年第4期397-414,共18页
Extreme climate events play an important role in studies of long-term climate change. As the Earth’s Third Pole, the Tibetan Plateau(TP) is sensitive to climate change and variation. In this study on the TP, the spat... Extreme climate events play an important role in studies of long-term climate change. As the Earth’s Third Pole, the Tibetan Plateau(TP) is sensitive to climate change and variation. In this study on the TP, the spatiotemporal changes in climate extreme indices(CEIs) are analyzed based on daily maximum and minimum surface air temperatures and precipitation at 98 meteorological stations, most with elevations of at least 4000 m above sea level, during 1960–2012. Fifteen temperature extreme indices(TEIs) and eight precipitation extreme indices(PEIs) were calculated. Then, their long-term change patterns, from spatial and temporal perspectives, were determined at regional, eco-regional and station levels. The entire TP region exhibits a significant warming trend, as reflected by the TEIs. The regional cold days and nights show decreasing trends at rates of-8.9 d(10 yr)-1(days per decade) and-17.3 d(10 yr)-1, respectively. The corresponding warm days and nights have increased by 7.6 d(10 yr)-1 and 12.5 d(10 yr)-1, respectively. At the station level, the majority of stations indicate statistically significant trends for all TEIs, but they show spatial heterogeneity. The eco-regional TEIs show patterns that are consistent with the entire TP. The growing season has become longer at a rate of 5.3 d(10 yr)^-1. The abrupt change points for CEIs were examined, and they were mainly distributed during the 1980 s and 1990 s. The PEIs on the TP exhibit clear fluctuations and increasing trends with small magnitudes. The annual total precipitation has increased by 2.8 mm(10 yr)^-1(not statistically significant). Most of the CEIs will maintain a persistent trend, as indicated by their Hurst exponents. The developing trends of the CEIs do not show a corresponding change with increasing altitude. In general, the warming trends demonstrate an asymmetric pattern reflected by the rapid increase in the warming trends of the cold TEIs, which are of greater magnitudes than those of the warm TEIs. This finding indicates a positive shift in the distribution of the daily minimum temperatures throughout the TP. Most of the PEIs show weak increasing trends, which are not statistically significant. This work aims to delineate a comprehensive picture of the extreme climate conditions over the TP that can enhance our understanding of its changing climate. 展开更多
关键词 Tibetan Plateau(TP) climate extreme indices(CEIs) trend analysis change point Hurst exponent
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