AIM: The role of motor dysfunction in early diagnosis of low-grade hepatic encephalopathy remains uncertain. We performed a pilot study to comparatively investigate the kinematic characteristics of small and large rap...AIM: The role of motor dysfunction in early diagnosis of low-grade hepatic encephalopathy remains uncertain. We performed a pilot study to comparatively investigate the kinematic characteristics of small and large rapid alternating movements in patients with liver cirrhosis and low-grade hepatic encephalopathy.METHODS: A kinematic analysis of alternating handwriting (7.5 mm) and large drawing movements (DM, 175 mm) was performed in 30 patients with liver cirrhosis (no hepatic encephalopathy: n = 10; minimal hepatic encephalopathy: n = 9; grade I hepatic encephalopathy: n = 11; healthy controls: n = 12). The correlation between kinematic parameters, clinical neuro-psychiatric symptoms of cerebral dysfunction and the grade of encephalopathy was investigated.RESULTS: Both movement types, handwriting and drawing, were significantly slower in cirrhotic patients. In contrast to large DM, the deterioration of handwriting movements significantly correlated with the increase of symptoms of motor dysfunction and differentiated significantly within the group of cirrhosis patients corresponding to the degree of hepatic encephalopathy. CONCLUSION: The deterioration of fine motor control is an important symptom of low-grade hepatic encephalopathy. The kinematic analysis of handwriting allows the quantitative analysis of alterations of motor function and is a possible tool for diagnostics and monitoring of motor dysfunction in patients with low-grade hepatic encephalopathy.展开更多
Objective: To study the effect of moxibustion on hyperbilirubinemia in hepatitis B cirrhosis patients. Methods: 56 cases of inpatients with hepatitis B cirrhosis were divided into treatment group (n=27) and control gr...Objective: To study the effect of moxibustion on hyperbilirubinemia in hepatitis B cirrhosis patients. Methods: 56 cases of inpatients with hepatitis B cirrhosis were divided into treatment group (n=27) and control group (n=29) randomly. All the patients of these two groups were given with routine expectant treatment including administration of medicines (Bifendate, Eessentiale, Potenline, etc) for protecting liver functions, reducing the level of alanine aminotransferase (ALT), etc., and in the meantime, patients of the treatment group were also treated with moxibustion of Zusanli (足三里 ST 36), Taichong (太冲 LR 3) and Sanyinjiao (三阴交 SP 6), once daily, continuously for 4 weeks. Results: After 4 weeks of treatment, of the 27 and 29 cases of treatment and control group, 23 and 10 patients had improvement in clinical symptoms, 4 and 19 failed, with the total effective rates being 85.18% and 34.48% respectively. Serum total bilirubin (TBil) contents of treatment and control groups decreased significantly, and the level of TBil in the treatment group was significantly lower than that in the control group (P<0.01). Conclusion: Moxibustion is an effective remedy in relieving hyperbilirubinemia and improving clinical symptoms in the treatment of hepatitis B cirrhosis patients.展开更多
Explaining the causes of infeasibility of Boolean formulas has many practical applications in electronic design automation and formal verification of hardware.Furthermore,a minimum explanation of infeasibility that ex...Explaining the causes of infeasibility of Boolean formulas has many practical applications in electronic design automation and formal verification of hardware.Furthermore,a minimum explanation of infeasibility that excludes all irrelevant information is generally of interest.A smallest-cardinality unsatisfiable subset called a minimum unsatisfiable core can provide a succinct explanation of infea-sibility and is valuable for applications.However,little attention has been concentrated on extraction of minimum unsatisfiable core.In this paper,the relationship between maximal satisfiability and mini-mum unsatisfiability is presented and proved,then an efficient ant colony algorithm is proposed to derive an exact or nearly exact minimum unsatisfiable core based on the relationship.Finally,ex-perimental results on practical benchmarks compared with the best known approach are reported,and the results show that the ant colony algorithm strongly outperforms the best previous algorithm.展开更多
The feeding habits of 140 specimens of Carcharhinus brachyurus （Fam. Carcharhinidae） inhabiting Ain-EI-Ghazala lagoon on the Mediterranean Sea, eastern Libya were studied monthly from February to June 2013. The annu...The feeding habits of 140 specimens of Carcharhinus brachyurus （Fam. Carcharhinidae） inhabiting Ain-EI-Ghazala lagoon on the Mediterranean Sea, eastern Libya were studied monthly from February to June 2013. The annual diet composition, monthly variations in the diet composition, the variations of diet with length and the intensity of feeding were studied. Carcharhinus brachyurus feed on a wide variety of prey types： Pelagic bony fishes （54.5%）, benthic bony fishes （36.4%）, Cephalopods （6.8%）, Cartilaginous fishes （1.7%） and Fish parts （0.6%）. The Pelagic bony fishes and benthic bony fishes were the major food items during the study period in question, and they were found in all length groups. According to the results that were gleamed from this study, when the size of the sharks increased, the proportion of pelagic bony fishes within the sharks＇ stomachs grew in size, while the benthic bony fishes and Cephalopods decreased in size. The feeding intensity was quite high during the winter, spring and summer, this study is the first to study the Elasmobranchs in Libya, and it will be good base to study another species, specifically.展开更多
文摘AIM: The role of motor dysfunction in early diagnosis of low-grade hepatic encephalopathy remains uncertain. We performed a pilot study to comparatively investigate the kinematic characteristics of small and large rapid alternating movements in patients with liver cirrhosis and low-grade hepatic encephalopathy.METHODS: A kinematic analysis of alternating handwriting (7.5 mm) and large drawing movements (DM, 175 mm) was performed in 30 patients with liver cirrhosis (no hepatic encephalopathy: n = 10; minimal hepatic encephalopathy: n = 9; grade I hepatic encephalopathy: n = 11; healthy controls: n = 12). The correlation between kinematic parameters, clinical neuro-psychiatric symptoms of cerebral dysfunction and the grade of encephalopathy was investigated.RESULTS: Both movement types, handwriting and drawing, were significantly slower in cirrhotic patients. In contrast to large DM, the deterioration of handwriting movements significantly correlated with the increase of symptoms of motor dysfunction and differentiated significantly within the group of cirrhosis patients corresponding to the degree of hepatic encephalopathy. CONCLUSION: The deterioration of fine motor control is an important symptom of low-grade hepatic encephalopathy. The kinematic analysis of handwriting allows the quantitative analysis of alterations of motor function and is a possible tool for diagnostics and monitoring of motor dysfunction in patients with low-grade hepatic encephalopathy.
文摘Objective: To study the effect of moxibustion on hyperbilirubinemia in hepatitis B cirrhosis patients. Methods: 56 cases of inpatients with hepatitis B cirrhosis were divided into treatment group (n=27) and control group (n=29) randomly. All the patients of these two groups were given with routine expectant treatment including administration of medicines (Bifendate, Eessentiale, Potenline, etc) for protecting liver functions, reducing the level of alanine aminotransferase (ALT), etc., and in the meantime, patients of the treatment group were also treated with moxibustion of Zusanli (足三里 ST 36), Taichong (太冲 LR 3) and Sanyinjiao (三阴交 SP 6), once daily, continuously for 4 weeks. Results: After 4 weeks of treatment, of the 27 and 29 cases of treatment and control group, 23 and 10 patients had improvement in clinical symptoms, 4 and 19 failed, with the total effective rates being 85.18% and 34.48% respectively. Serum total bilirubin (TBil) contents of treatment and control groups decreased significantly, and the level of TBil in the treatment group was significantly lower than that in the control group (P<0.01). Conclusion: Moxibustion is an effective remedy in relieving hyperbilirubinemia and improving clinical symptoms in the treatment of hepatitis B cirrhosis patients.
基金the National Natural Science Foundation of China (No.60603088)
文摘Explaining the causes of infeasibility of Boolean formulas has many practical applications in electronic design automation and formal verification of hardware.Furthermore,a minimum explanation of infeasibility that excludes all irrelevant information is generally of interest.A smallest-cardinality unsatisfiable subset called a minimum unsatisfiable core can provide a succinct explanation of infea-sibility and is valuable for applications.However,little attention has been concentrated on extraction of minimum unsatisfiable core.In this paper,the relationship between maximal satisfiability and mini-mum unsatisfiability is presented and proved,then an efficient ant colony algorithm is proposed to derive an exact or nearly exact minimum unsatisfiable core based on the relationship.Finally,ex-perimental results on practical benchmarks compared with the best known approach are reported,and the results show that the ant colony algorithm strongly outperforms the best previous algorithm.
文摘The feeding habits of 140 specimens of Carcharhinus brachyurus （Fam. Carcharhinidae） inhabiting Ain-EI-Ghazala lagoon on the Mediterranean Sea, eastern Libya were studied monthly from February to June 2013. The annual diet composition, monthly variations in the diet composition, the variations of diet with length and the intensity of feeding were studied. Carcharhinus brachyurus feed on a wide variety of prey types： Pelagic bony fishes （54.5%）, benthic bony fishes （36.4%）, Cephalopods （6.8%）, Cartilaginous fishes （1.7%） and Fish parts （0.6%）. The Pelagic bony fishes and benthic bony fishes were the major food items during the study period in question, and they were found in all length groups. According to the results that were gleamed from this study, when the size of the sharks increased, the proportion of pelagic bony fishes within the sharks＇ stomachs grew in size, while the benthic bony fishes and Cephalopods decreased in size. The feeding intensity was quite high during the winter, spring and summer, this study is the first to study the Elasmobranchs in Libya, and it will be good base to study another species, specifically.
