To track the rapidly changing temperature profiles of thermal cycling of polymerase chain reaction （PCR） accurately, an innovative feedforward variable structural proportional-integral-derivative （FVSPID） controll...To track the rapidly changing temperature profiles of thermal cycling of polymerase chain reaction （PCR） accurately, an innovative feedforward variable structural proportional-integral-derivative （FVSPID） controller was developed. Based on the step response test data of the heat block, a reduced first order model was estabfished at different operating points. Based on the reduced model, the FVSPID controller combined a feedforward path with the variable structural proportional-integral-derivative （PID） control. The modified feedforward action provided directly the optimal predictive power for the desired setpoint to speed up the dynamic response. To cooperate with the feedforward action, a variable structural PID was applied, where the P mode was used in the case of the largest errors to speed up response, whereas the PD mode was used in the case of larger errors to suppress overshoot, and finally the PID mode was applied for small error conditions to eliminate the steady state offset. Experimental results illustrated that compared to the conventional PID controller, the FVSPID controller can not only reduce the time taken to complete a standard PCR protocol, but also improve the accuracy of gene amplification.展开更多
This paper deals with the adaptive practical output maneuvering control problems for a class of nonlinear systems with uncontrollable unstable linearization. The objective is to design a smooth adaptive maneuvering co...This paper deals with the adaptive practical output maneuvering control problems for a class of nonlinear systems with uncontrollable unstable linearization. The objective is to design a smooth adaptive maneuvering controller to solve the geometric and dynamic tasks with an arbitrary small steady tracking error. The method of adding a power integrator and the robust recursive design technique are employed to force the system output to track a desired path and make the tracking speed to follow a desired speed along the path. An example is considered and simulation results are given. The proposed design procedure can be illustrated by the use of this example.展开更多
基金Supported by the National Natural Science Foundation of China (No.60574038) and the Open Project Program of the State KeyLaboratory of Bioreactor Engineering/ECUST.
文摘To track the rapidly changing temperature profiles of thermal cycling of polymerase chain reaction （PCR） accurately, an innovative feedforward variable structural proportional-integral-derivative （FVSPID） controller was developed. Based on the step response test data of the heat block, a reduced first order model was estabfished at different operating points. Based on the reduced model, the FVSPID controller combined a feedforward path with the variable structural proportional-integral-derivative （PID） control. The modified feedforward action provided directly the optimal predictive power for the desired setpoint to speed up the dynamic response. To cooperate with the feedforward action, a variable structural PID was applied, where the P mode was used in the case of the largest errors to speed up response, whereas the PD mode was used in the case of larger errors to suppress overshoot, and finally the PID mode was applied for small error conditions to eliminate the steady state offset. Experimental results illustrated that compared to the conventional PID controller, the FVSPID controller can not only reduce the time taken to complete a standard PCR protocol, but also improve the accuracy of gene amplification.
基金Supported by the National Natural Science Foundation of China （No. 60304003, 60574007, and 60574080）.
文摘This paper deals with the adaptive practical output maneuvering control problems for a class of nonlinear systems with uncontrollable unstable linearization. The objective is to design a smooth adaptive maneuvering controller to solve the geometric and dynamic tasks with an arbitrary small steady tracking error. The method of adding a power integrator and the robust recursive design technique are employed to force the system output to track a desired path and make the tracking speed to follow a desired speed along the path. An example is considered and simulation results are given. The proposed design procedure can be illustrated by the use of this example.
