Children(5-12 years) and adolescents(13-19 years) with Down syndrome(DS) possess a set of health,anatomical,physiological, cognitive,and psycho-social attributes predisposing them to limitations on their physical fitn...Children(5-12 years) and adolescents(13-19 years) with Down syndrome(DS) possess a set of health,anatomical,physiological, cognitive,and psycho-social attributes predisposing them to limitations on their physical fitness and physical activity(PA) capacities.The paucity of studies and their conflicting findings prevent a clear understanding and/or substantiation of these limitations.The purpose of this article was to review the measurement,determinants and promotion of physical fitness and PA for youth(i.e.,children and adolescents) with DS. The existing body of research indicates that youth with DS:1) have low cardiovascular and muscular fitness/exercise capacity;2) demonstrate a greater prevalence of overweight and obesity;3) a large proportion do not meet the recommended amount of daily aerobic activity;and 4) their PA likely declines through childhood and into adolescence.Future research should focus on:1) strength testing and training protocols;2) methodologies to determine PA levels;and 3) practical interventions to increase PA.展开更多
In the 2013 release of the U.S. National Physical Education Standards the term "physically literate" replaced "physically educated". Un- fortunately, most discourse within the profession about the term physically ...In the 2013 release of the U.S. National Physical Education Standards the term "physically literate" replaced "physically educated". Un- fortunately, most discourse within the profession about the term physically literate occurred primarily after its adoption. While we agree with the spirit and intent of the term, we feel it is essential to discuss not only what has been potentially gained but also lost. In our paper, we illustrate the similarity of the terms physically educated and physically literate and essentially, from a definitional perspective, find little difference--but are these terms interchangeable? We provide a critical review of the standards and conclude that the change to physical literacy has produced a shift away from psychomotor outcomes to cognitive outcomes. Our concerns about this are many, but most importantly they are about the need to emphasize the "physical" in physical education (PE). It is our belief that the key to elevating the profession and maintaining and increasing support for PE is in its ability to promote and provide physical activity. Without physical activity and physical fitness as main outcomes, PE increases its vulnerability to extinction as a standard part of the U.S. K-12 education curriculum.展开更多
AIM: To investigate the risk factors for gallstone disease in the general population of Chengdu, China. METHODS: This study was conducted at the West China Hospital. Subjects who received a physical examination at t...AIM: To investigate the risk factors for gallstone disease in the general population of Chengdu, China. METHODS: This study was conducted at the West China Hospital. Subjects who received a physical examination at this hospital between January and December 2007 were included. Body mass index, blood pressure, fasting plasma glucose, serum lipid and lipoproteins concentrations were analyzed. Gallstone disease was diagnosed by ultrasound or on the basis of a history of cholecystectomy because of gallstone disease. Unconditional logistic regression analysis was used to investigate the risk factors for gallstone disease, and the Chi-square test was used to analyze differences in the incidence of metabolic disorders between subjects with and without gallstone disease. RESULTS: A total of 3573 people were included, 10.7% (384/3573) of whom had gallstone diseases. Multiple logistic regression analysis indicated that the incidence of gallstone disease in subjects aged 40-64 or ≥65 years was significantly different from that in those aged 18-39 years (P 〈 0.05); the incidence was higher in women than in men (P 〈 0.05). In men,a high level of fasting plasma glucose was obvious in gallstone disease (P 〈 0.05), and in women, hypertriglyceridemia or obesity were significant in gallstone disease (P 〈 0.05). CONCLUSION: We assume that age and sex are profoundly associated with the incidence of gallstone disease; the metabolic risk factors for gallstone disease were different between men and women.展开更多
We describe a case of a 33-year-old female patient with chronic hepatitis B who developed type 1 diabetes mellitus (DM) after a 13-mo period of treatment with recombinant human interferon-alpha (IFN-α) 2b. The patien...We describe a case of a 33-year-old female patient with chronic hepatitis B who developed type 1 diabetes mellitus (DM) after a 13-mo period of treatment with recombinant human interferon-alpha (IFN-α) 2b. The patient presented with polydipsia, polyuria, hypergly-cemia, diabetic ketoacidosis, combined with C-peptide secretion defi ciency and positive islet cell autoantibody (ICAb). IFN-α 2b treatment was terminated and in-stead insulin treatment was initiated. Five months after cessation of the recombinant human IFN-α 2b therapy, the patient remained insulin-dependent. Her serum HBV DNA became negative and serum transaminase returned to the normal level after a 10-mo period of IFN therapy. Type 1 DM induced by IFN-α is relatively rare in patients with chronic hepatitis B. We should pay more attention to patients on IFN-α therapy to avoid destruction of pancreatic beta cells. This is the first case report from China.展开更多
Most anemia is related to the digestive system by dietary deficiency, malabsorption, or chronic bleeding. We review the World Health Organization definition of anemia, its morphological classifi cation (microcytic, ma...Most anemia is related to the digestive system by dietary deficiency, malabsorption, or chronic bleeding. We review the World Health Organization definition of anemia, its morphological classifi cation (microcytic, macrocytic and normocytic) and pathogenic classi-fication (regenerative and hypo regenerative), and integration of these classifications. Interpretation of laboratory tests is included, from the simplest (blood count, routine biochemistry) to the more specific (iron metabolism, vitamin B12, folic acid, reticulocytes, erythropoietin, bone marrow examination and Schilling test). In the text and various algorithms, we propose a hierarchical and logical way to reach a diagnosis as quickly as possible, by properly managing the medical interview, physical examination, appropriate laboratory tests, bone marrow examination, and other comple-mentary tests. The prevalence is emphasized in all sections so that the gastroenterologist can direct the diagnosis to the most common diseases, although the tables also include rare diseases. Digestive diseases potentially causing anemia have been studied in preference, but other causes of anemia have been included in the text and tables. Primitive hematological diseases that cause anemia are only listed, but are not discussed in depth. The last section is dedicated to simplifying all items discussed above, using practical rules to guide diagnosis and medical care with the greatest economy of resources and time.展开更多
Schools and parents should pay attention to health education for students' health awareness and good health habits, to establish a correct concept of health. School mental health education should be the first place; ...Schools and parents should pay attention to health education for students' health awareness and good health habits, to establish a correct concept of health. School mental health education should be the first place; school should create a positive learning environment for students to get knowledge and skills of exercising. Especially in the nine years of compulsory education stage, we should ensure necessary physical exercise, reasonable arrangements for extracurricular activities to improve students' physical fitness. We should improve the school' s sports facilities, and create a good campus atmosphere. Schools should actively carry out extra-curricular sports activities, improve the level of quality of physical education teachers, develop students' sports consciousness, and improve material conditions for the students to create a good learning environment, meanwhile, we should increase the content of education, and enrich the content of physical education to enable students to select and reach more sports.展开更多
An 8-week feeding experiment was performed to evaluate the effect of dietary genistein on growth performance,body composition,and digestive enzymes activity of juvenile Nile tilapia(Oreochromis niloticus).Four isonitr...An 8-week feeding experiment was performed to evaluate the effect of dietary genistein on growth performance,body composition,and digestive enzymes activity of juvenile Nile tilapia(Oreochromis niloticus).Four isonitrogenous and isoenergetic diets were formulated containing four graded supplements of genistein:0,30,300,and 3 000 μg/g.Each diet was randomly assigned in triplicate to tanks stocked with 15 juvenile tilapia(10.47±1.24 g).The results show that 30 and 300 μg/gdietary genistein had no significant effect on growth performance of Nile tilapia,but the higher level of genistein(3 000 μg/g)significantly depressed the final body weight and specific growth rate.There was no significant difference in survival rate,feed intake,feed efficiency ratio or whole body composition among all dietary treatments.An assay of digestive enzymes showed that the diet containing 3 000 μg/ggenistein decreased stomach and hepatopancreas protease activity,and amylase activity in the liver and intestine,while a dietary level of300 μg/g genistein depressed stomach protease and intestine amylase activities.However,no significant difference in stomach amylase activity was found among dietary treatments.Overall,the results of the present study indicate that a high level of dietary genistein(3 000 μg/g,or above) would significantly reduce the growth of Nile tilapia,partly because of its inhibitory effect on the activity of major digestive enzymes.Accordingly,the detrimental effects of genistein,as found in soybean products,should not be ignored when applied as an alternative ingredient source in aquaculture.展开更多
During the last thirty years the main interest in the medical consequences of milling of staple carbohydrate foods, particularly wheat and maize, has been in its effect on the fibre content as a result of the milling....During the last thirty years the main interest in the medical consequences of milling of staple carbohydrate foods, particularly wheat and maize, has been in its effect on the fibre content as a result of the milling. The late nineteenth and early twentieth centuries in the West saw great changes in milling processes, from stone milling using water or wind power, to increasingly sophisticated roller milling, with an展开更多
AIM:To evaluate the possible relationship between varicocele and chronic constipation.METHODS:Between April 2009 and May 2010,a total of 135 patients with varicocele or constipation and 120 healthy controls were evalu...AIM:To evaluate the possible relationship between varicocele and chronic constipation.METHODS:Between April 2009 and May 2010,a total of 135 patients with varicocele or constipation and 120 healthy controls were evaluated.Patients were divided into two groups.In both groups detailed medical history was taken and all patients were examined physically by the same urologist and gastroenterologist.All of them were evaluated by color Doppler ultrasonography.All patients with constipation,except for the healthy controls of the second group,underwent a colonoscopy to identify the etiology of the constipation.In the first group,we determined the rate of chronic constipation in patients with varicocele and in the second group,the rate of varicocele in patients with chronic constipation.In both groups,the rate of the disease was compared with age-matched healthy controls.In the second group,the results of colonoscopies in the patients with chronic constipations were also evaluated.RESULTS:In the first group,mean age of the study and control groups were 22.9 ± 4.47 and 21.8 ± 7.21 years,respectively(P < 0.05).In the second group,mean age of the study and control groups were 52.8 ± 33.3 and 51.7 ± 54.3 years,respectively(P < 0.05).In the first group,chronic constipation was observed in 8 of the 69 patients with varicocele(11.6%) and 3 out of 60 in healthy controls(5%),respectively.In this regard,there was no statistical significance between varicocele patients and the healthy control(P = 0.37).In the second group,varicocele was observed in 16 of the 66 patients with chronic constipation(24.24%) and 12 out of 60 in healthy controls(20%) respectively.Similarly,there was no statistical significance between chronic constipation and healthy controls(P = 0.72).Internal/external hemorrhoids were detected in 4 of the 16 patients with chronic constipation and varicocele,in the second group.In the remaining 50 patients with chronic constipation 9 had internal/external hemorrhoids.In this regard,there was no statistical significance between chronic constipation and healthy controls(P = 0.80).CONCLUSION:Chronic constipation may not be a major predictive factor for the development of varicocele,but it may be a facilitator factor for varicocele.展开更多
During our research,It has been found that body acceleration has strong relationships with the human energy expenditure.This paper discusses the methods to assess physical activity and concludes that for accurate asse...During our research,It has been found that body acceleration has strong relationships with the human energy expenditure.This paper discusses the methods to assess physical activity and concludes that for accurate assessment of physical activity under free living conditions the recently introduced accelerometer looks most promising.We developed a new computerized machine to assess the body activity and energy expenditure.Test datas of the treadmill experiment,respiration experiment and 5-kilometer-running experiment have been archieved,we found that body acceration integrals with time has linear relations with body energy expenture.展开更多
Differences among species in prosome length and in species' response to environmental factors do exist. Therefore, it is useful to examine prosome length for different copepod species in variable environments. Sea...Differences among species in prosome length and in species' response to environmental factors do exist. Therefore, it is useful to examine prosome length for different copepod species in variable environments. Seasonal variations in prosome length of four small copepods and their copepodite stages in the Jiaozhou Bay were compared and the relative influence of temperature, salinity, and chlorophyll concentration were examined. Two peaks were found in the mean prosome length of Paracalanus parvus (in early winter and May). For Acartia bifilosa, the maximum values of all copepodites occurred mainly from February to April, and decreased to the bottom in July. Prosome length of Acartia pacifica peaked when it first appeared in June, then reached to the minimum in July. Parvocalanus crassirostris only appeared from late summer to autumn and the mean prosome length showed no clear changes. Correlations of adult prosome length with environmental factors were evaluated. For the four species, temperature was negatively correlated to prosome length except for P. crassirostris. But the different species varied markedly in their responds to temperature. A. bifilosa showed a more definite trend of size variation with temperature than P. parvus and A. pacifica. Correlations of prosome length with salinity were significantly positive for almost all the small copepods. The relationship between chlorophyll concentration and prosome length was complicated for these copepods, but for P. parvus, chlorophyll concentration was also an important affecting factor. Furthermore, investigation needs to be done on food quality for some copepod. These results are essential to estimate the biomass and the production, and to understand these small copepods' population dynamics in this human-affected bay.展开更多
文摘Children(5-12 years) and adolescents(13-19 years) with Down syndrome(DS) possess a set of health,anatomical,physiological, cognitive,and psycho-social attributes predisposing them to limitations on their physical fitness and physical activity(PA) capacities.The paucity of studies and their conflicting findings prevent a clear understanding and/or substantiation of these limitations.The purpose of this article was to review the measurement,determinants and promotion of physical fitness and PA for youth(i.e.,children and adolescents) with DS. The existing body of research indicates that youth with DS:1) have low cardiovascular and muscular fitness/exercise capacity;2) demonstrate a greater prevalence of overweight and obesity;3) a large proportion do not meet the recommended amount of daily aerobic activity;and 4) their PA likely declines through childhood and into adolescence.Future research should focus on:1) strength testing and training protocols;2) methodologies to determine PA levels;and 3) practical interventions to increase PA.
文摘In the 2013 release of the U.S. National Physical Education Standards the term "physically literate" replaced "physically educated". Un- fortunately, most discourse within the profession about the term physically literate occurred primarily after its adoption. While we agree with the spirit and intent of the term, we feel it is essential to discuss not only what has been potentially gained but also lost. In our paper, we illustrate the similarity of the terms physically educated and physically literate and essentially, from a definitional perspective, find little difference--but are these terms interchangeable? We provide a critical review of the standards and conclude that the change to physical literacy has produced a shift away from psychomotor outcomes to cognitive outcomes. Our concerns about this are many, but most importantly they are about the need to emphasize the "physical" in physical education (PE). It is our belief that the key to elevating the profession and maintaining and increasing support for PE is in its ability to promote and provide physical activity. Without physical activity and physical fitness as main outcomes, PE increases its vulnerability to extinction as a standard part of the U.S. K-12 education curriculum.
基金The National Natural Science Foundation of China,No.30571640the National Basic Research Program of China,No.2006CB504302 and No.2007CB512902
文摘AIM: To investigate the risk factors for gallstone disease in the general population of Chengdu, China. METHODS: This study was conducted at the West China Hospital. Subjects who received a physical examination at this hospital between January and December 2007 were included. Body mass index, blood pressure, fasting plasma glucose, serum lipid and lipoproteins concentrations were analyzed. Gallstone disease was diagnosed by ultrasound or on the basis of a history of cholecystectomy because of gallstone disease. Unconditional logistic regression analysis was used to investigate the risk factors for gallstone disease, and the Chi-square test was used to analyze differences in the incidence of metabolic disorders between subjects with and without gallstone disease. RESULTS: A total of 3573 people were included, 10.7% (384/3573) of whom had gallstone diseases. Multiple logistic regression analysis indicated that the incidence of gallstone disease in subjects aged 40-64 or ≥65 years was significantly different from that in those aged 18-39 years (P 〈 0.05); the incidence was higher in women than in men (P 〈 0.05). In men,a high level of fasting plasma glucose was obvious in gallstone disease (P 〈 0.05), and in women, hypertriglyceridemia or obesity were significant in gallstone disease (P 〈 0.05). CONCLUSION: We assume that age and sex are profoundly associated with the incidence of gallstone disease; the metabolic risk factors for gallstone disease were different between men and women.
文摘We describe a case of a 33-year-old female patient with chronic hepatitis B who developed type 1 diabetes mellitus (DM) after a 13-mo period of treatment with recombinant human interferon-alpha (IFN-α) 2b. The patient presented with polydipsia, polyuria, hypergly-cemia, diabetic ketoacidosis, combined with C-peptide secretion defi ciency and positive islet cell autoantibody (ICAb). IFN-α 2b treatment was terminated and in-stead insulin treatment was initiated. Five months after cessation of the recombinant human IFN-α 2b therapy, the patient remained insulin-dependent. Her serum HBV DNA became negative and serum transaminase returned to the normal level after a 10-mo period of IFN therapy. Type 1 DM induced by IFN-α is relatively rare in patients with chronic hepatitis B. We should pay more attention to patients on IFN-α therapy to avoid destruction of pancreatic beta cells. This is the first case report from China.
文摘Most anemia is related to the digestive system by dietary deficiency, malabsorption, or chronic bleeding. We review the World Health Organization definition of anemia, its morphological classifi cation (microcytic, macrocytic and normocytic) and pathogenic classi-fication (regenerative and hypo regenerative), and integration of these classifications. Interpretation of laboratory tests is included, from the simplest (blood count, routine biochemistry) to the more specific (iron metabolism, vitamin B12, folic acid, reticulocytes, erythropoietin, bone marrow examination and Schilling test). In the text and various algorithms, we propose a hierarchical and logical way to reach a diagnosis as quickly as possible, by properly managing the medical interview, physical examination, appropriate laboratory tests, bone marrow examination, and other comple-mentary tests. The prevalence is emphasized in all sections so that the gastroenterologist can direct the diagnosis to the most common diseases, although the tables also include rare diseases. Digestive diseases potentially causing anemia have been studied in preference, but other causes of anemia have been included in the text and tables. Primitive hematological diseases that cause anemia are only listed, but are not discussed in depth. The last section is dedicated to simplifying all items discussed above, using practical rules to guide diagnosis and medical care with the greatest economy of resources and time.
文摘Schools and parents should pay attention to health education for students' health awareness and good health habits, to establish a correct concept of health. School mental health education should be the first place; school should create a positive learning environment for students to get knowledge and skills of exercising. Especially in the nine years of compulsory education stage, we should ensure necessary physical exercise, reasonable arrangements for extracurricular activities to improve students' physical fitness. We should improve the school' s sports facilities, and create a good campus atmosphere. Schools should actively carry out extra-curricular sports activities, improve the level of quality of physical education teachers, develop students' sports consciousness, and improve material conditions for the students to create a good learning environment, meanwhile, we should increase the content of education, and enrich the content of physical education to enable students to select and reach more sports.
基金Supported by the National Natural Science Foundation of China(No.31170322)
文摘An 8-week feeding experiment was performed to evaluate the effect of dietary genistein on growth performance,body composition,and digestive enzymes activity of juvenile Nile tilapia(Oreochromis niloticus).Four isonitrogenous and isoenergetic diets were formulated containing four graded supplements of genistein:0,30,300,and 3 000 μg/g.Each diet was randomly assigned in triplicate to tanks stocked with 15 juvenile tilapia(10.47±1.24 g).The results show that 30 and 300 μg/gdietary genistein had no significant effect on growth performance of Nile tilapia,but the higher level of genistein(3 000 μg/g)significantly depressed the final body weight and specific growth rate.There was no significant difference in survival rate,feed intake,feed efficiency ratio or whole body composition among all dietary treatments.An assay of digestive enzymes showed that the diet containing 3 000 μg/ggenistein decreased stomach and hepatopancreas protease activity,and amylase activity in the liver and intestine,while a dietary level of300 μg/g genistein depressed stomach protease and intestine amylase activities.However,no significant difference in stomach amylase activity was found among dietary treatments.Overall,the results of the present study indicate that a high level of dietary genistein(3 000 μg/g,or above) would significantly reduce the growth of Nile tilapia,partly because of its inhibitory effect on the activity of major digestive enzymes.Accordingly,the detrimental effects of genistein,as found in soybean products,should not be ignored when applied as an alternative ingredient source in aquaculture.
文摘During the last thirty years the main interest in the medical consequences of milling of staple carbohydrate foods, particularly wheat and maize, has been in its effect on the fibre content as a result of the milling. The late nineteenth and early twentieth centuries in the West saw great changes in milling processes, from stone milling using water or wind power, to increasingly sophisticated roller milling, with an
文摘AIM:To evaluate the possible relationship between varicocele and chronic constipation.METHODS:Between April 2009 and May 2010,a total of 135 patients with varicocele or constipation and 120 healthy controls were evaluated.Patients were divided into two groups.In both groups detailed medical history was taken and all patients were examined physically by the same urologist and gastroenterologist.All of them were evaluated by color Doppler ultrasonography.All patients with constipation,except for the healthy controls of the second group,underwent a colonoscopy to identify the etiology of the constipation.In the first group,we determined the rate of chronic constipation in patients with varicocele and in the second group,the rate of varicocele in patients with chronic constipation.In both groups,the rate of the disease was compared with age-matched healthy controls.In the second group,the results of colonoscopies in the patients with chronic constipations were also evaluated.RESULTS:In the first group,mean age of the study and control groups were 22.9 ± 4.47 and 21.8 ± 7.21 years,respectively(P < 0.05).In the second group,mean age of the study and control groups were 52.8 ± 33.3 and 51.7 ± 54.3 years,respectively(P < 0.05).In the first group,chronic constipation was observed in 8 of the 69 patients with varicocele(11.6%) and 3 out of 60 in healthy controls(5%),respectively.In this regard,there was no statistical significance between varicocele patients and the healthy control(P = 0.37).In the second group,varicocele was observed in 16 of the 66 patients with chronic constipation(24.24%) and 12 out of 60 in healthy controls(20%) respectively.Similarly,there was no statistical significance between chronic constipation and healthy controls(P = 0.72).Internal/external hemorrhoids were detected in 4 of the 16 patients with chronic constipation and varicocele,in the second group.In the remaining 50 patients with chronic constipation 9 had internal/external hemorrhoids.In this regard,there was no statistical significance between chronic constipation and healthy controls(P = 0.80).CONCLUSION:Chronic constipation may not be a major predictive factor for the development of varicocele,but it may be a facilitator factor for varicocele.
文摘During our research,It has been found that body acceleration has strong relationships with the human energy expenditure.This paper discusses the methods to assess physical activity and concludes that for accurate assessment of physical activity under free living conditions the recently introduced accelerometer looks most promising.We developed a new computerized machine to assess the body activity and energy expenditure.Test datas of the treadmill experiment,respiration experiment and 5-kilometer-running experiment have been archieved,we found that body acceration integrals with time has linear relations with body energy expenture.
基金Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX2-YW-213-3)the National Basic Research Program of China (973 Program) (No. 2006CB400606)the National Natural Science Foundation of China (No. 40631008)
文摘Differences among species in prosome length and in species' response to environmental factors do exist. Therefore, it is useful to examine prosome length for different copepod species in variable environments. Seasonal variations in prosome length of four small copepods and their copepodite stages in the Jiaozhou Bay were compared and the relative influence of temperature, salinity, and chlorophyll concentration were examined. Two peaks were found in the mean prosome length of Paracalanus parvus (in early winter and May). For Acartia bifilosa, the maximum values of all copepodites occurred mainly from February to April, and decreased to the bottom in July. Prosome length of Acartia pacifica peaked when it first appeared in June, then reached to the minimum in July. Parvocalanus crassirostris only appeared from late summer to autumn and the mean prosome length showed no clear changes. Correlations of adult prosome length with environmental factors were evaluated. For the four species, temperature was negatively correlated to prosome length except for P. crassirostris. But the different species varied markedly in their responds to temperature. A. bifilosa showed a more definite trend of size variation with temperature than P. parvus and A. pacifica. Correlations of prosome length with salinity were significantly positive for almost all the small copepods. The relationship between chlorophyll concentration and prosome length was complicated for these copepods, but for P. parvus, chlorophyll concentration was also an important affecting factor. Furthermore, investigation needs to be done on food quality for some copepod. These results are essential to estimate the biomass and the production, and to understand these small copepods' population dynamics in this human-affected bay.