The Dieline 2015国际包装设计大奖结果已揭晓,中国品牌农夫山泉高端玻璃瓶装矿泉水包装荣获"非酒精饮料类包装设计冠军",这款包装用时3年,一共经历了58稿、300余个设计才最终定型。不仅是农夫山泉在矿泉水包装上求新,反观各...The Dieline 2015国际包装设计大奖结果已揭晓,中国品牌农夫山泉高端玻璃瓶装矿泉水包装荣获"非酒精饮料类包装设计冠军",这款包装用时3年,一共经历了58稿、300余个设计才最终定型。不仅是农夫山泉在矿泉水包装上求新,反观各大超市、便利店越来越丰富的水包装,其他品牌商在提升水包装颜值上也真是蛮拼的。尤其是新国标《食品安全国家标准包装饮用水》(GB19298-2014)开始实施,蒸馏水、冰川水、离子水、小分子水等各种概念水,将统统退出市场。不能在名称上"炒概念"了,未来如何争夺市场?各大品牌商必将在水包装上下足功夫。在此,分享几款有创意的饮料包装,看标签是如何助饮料拼颜值的。展开更多
Autoimmune pancreatitis (AIP) is a particular type of pancreatitis of presumed autoimmune etiology. Currently, AIP should be diagnosed based on combination of clinical, serological, morphological, and histopathologi...Autoimmune pancreatitis (AIP) is a particular type of pancreatitis of presumed autoimmune etiology. Currently, AIP should be diagnosed based on combination of clinical, serological, morphological, and histopathological features. When diagnosing AIP, it is most important to differentiate it from pancreatic cancer. Diagnostic criteria for AIP, proposed by the Japan Pancreas Society in 2002 first in the world, were revised in 2006. The criteria are based on the minimum consensus of AIP and aim to avoid misdiagnosing pancreatic cancer as far as possible, but not for screening AIR The criteria consist of the following radiological, serological, and histopathological items: (1) radiological imaging showing narrowing of the main pancreatic duct and enlargement of the pancreas, which are characteristic of the disease; (2) laboratory data showing abnormally elevated levels of serum y-globulin, IgG or IgG4, or the presence of autoantibodies; (3) histopathological examination of the pancreas demonstrating marked fibrosis and prominent infiltration of lymphocytes and plasma cells, which is called lymphoplasmacytic sclerosing pancreatitis (LPSP). For a diagnosis of AIP, criterion 1 must be present, together with criterion 2 and/ or criterion 3. However, it is necessary to exclude malignant diseases such as pancreatic or biliary cancer.展开更多
AIM: To study if and how physicians use the irritable bowel syndrome (IBS) diagnostic criteria and to assess treatment strategies in IBS patients. METHODS: A questionnaire was sent to 191 physicians regarding IBS crit...AIM: To study if and how physicians use the irritable bowel syndrome (IBS) diagnostic criteria and to assess treatment strategies in IBS patients. METHODS: A questionnaire was sent to 191 physicians regarding IBS criteria, diagnostic methods and treatment. Furthermore, 94 patients who were diagnosed with IBS underwent telephone interview. RESULTS: A total of 80/191 (41.9%) physicians responded to the survey. Overall, 13 patients were diag-nosed monthly with IBS by specialists in gastroenterology (SGs) and 2.5 patients by general practitioners (GPs). All the SGs knew of the criteria to diagnose IBS, as did 46/70 (65.7%) GPs. Seventy-nine percent used the patient's history, 38% used a physical examination, and 38% exclusion of other diseases to diagnose IBS. Only 18/80 (22.5%) physicians used specific IBS criteria. Of the patients interviewed, 59/94 (62.8%) knew they had experienced IBS. Two out of five patients knew IBS and had seen a physician because of IBS symptoms. Half of those received a diagnosis of IBS. A total of 13% were satisfied with treatment. IBS affected daily activities in 43% of cases. CONCLUSION: Half of the patients with IBS who consulted a physician received a diagnosis. Awareness and knowledge of diagnostic criteria for IBS differ between SGs and GPs.展开更多
Most complications after appendectomy occur within ten days; however, we report the unusual case of a suture granuloma 12 years after open appendectomy. The afebrile 75-year-old woman presented with a slightly painful...Most complications after appendectomy occur within ten days; however, we report the unusual case of a suture granuloma 12 years after open appendectomy. The afebrile 75-year-old woman presented with a slightly painful palpable mass in the right lower abdomen. There was no nausea or vomiting and bowel movements were normal. She lost 10 kg during the 3 mo before presentation. The patient had undergone an appendectomy 12 years previously. Physical examination revealed a tender mass, 10 cm in diameter, under the appendectomy scar. The preoperative laboratory findings, tumor markers and plain abdominal radiographs were normal. Multi-slice computed tomography scanning showed an inhomo-genous abdominal mass with minimal vascularization in the right lower abdomen 8.6cm×8cm×9 cm in size which communicated with the abdominal wall. The abdominal wall was thickened, weak and bulging. The abdominal wall mass did not communicate with the cecum or the ascending colon. Complete excision of the abdominal wall mass was performed via median laparotomy. Histopathological examination revealed a granuloma with a central abscess. This case report demonstrates that a preoperative diagnosis of abdominal wall mass after open appendectomy warrants the use of a wide spectrum of diagnostic modalities and consequently different treatment options.展开更多
In the 2013 release of the U.S. National Physical Education Standards the term "physically literate" replaced "physically educated". Un- fortunately, most discourse within the profession about the term physically ...In the 2013 release of the U.S. National Physical Education Standards the term "physically literate" replaced "physically educated". Un- fortunately, most discourse within the profession about the term physically literate occurred primarily after its adoption. While we agree with the spirit and intent of the term, we feel it is essential to discuss not only what has been potentially gained but also lost. In our paper, we illustrate the similarity of the terms physically educated and physically literate and essentially, from a definitional perspective, find little difference--but are these terms interchangeable? We provide a critical review of the standards and conclude that the change to physical literacy has produced a shift away from psychomotor outcomes to cognitive outcomes. Our concerns about this are many, but most importantly they are about the need to emphasize the "physical" in physical education (PE). It is our belief that the key to elevating the profession and maintaining and increasing support for PE is in its ability to promote and provide physical activity. Without physical activity and physical fitness as main outcomes, PE increases its vulnerability to extinction as a standard part of the U.S. K-12 education curriculum.展开更多
Autoimmune hepatitis (AIH) is a progressive inflammatory liver disorder that is rare in children and adolescents. AIH has a broad clinical spectrum and a quick response to treatment with corticosteroids and immunosupp...Autoimmune hepatitis (AIH) is a progressive inflammatory liver disorder that is rare in children and adolescents. AIH has a broad clinical spectrum and a quick response to treatment with corticosteroids and immunosuppressive medication. The available diagnosis criteria have limitations and should be evaluated in pediatric populations. Recently, some studies reported that the 2008 simplified diagnostic criteria for AIH could be used in children with high sensibility and specificity. In addition, the authors reported that globulin and immunoglobulin G levels can be used interchangeably for diagnostic purposes. They also demonstrated that the 2008 simplified criteria fail in identifying patients with fulminant hepatic failure. Here, we discuss the limitations of the use of these criteria in pediatric patients and the requirement of more studies to improve the diagnosis of AIH in children.展开更多
The similarities and differences of ASTM and China GB standard are studied in three aspects:measure instrument,terminology and applicable field.They are similar on the measuring apparatus and GB has less measurements,...The similarities and differences of ASTM and China GB standard are studied in three aspects:measure instrument,terminology and applicable field.They are similar on the measuring apparatus and GB has less measurements,such as girth,length and width measurements than ASTM and it lack across chest width,back width,total crotch length and shoulder slope which are important measurements in pattern making.ASTM classifies its standards according to the customers' size,gender and age.So we think GB standard could make some modifications from these fields to satisfy the users.展开更多
AIM: To evaluate the effectiveness of three-dimensional endoanal ultrasound (3D-EAUS) in the assessment of anal fistulae with and without H202 enhancement. METHODS: Sixty-one patients (37 males, aged 17-74 years...AIM: To evaluate the effectiveness of three-dimensional endoanal ultrasound (3D-EAUS) in the assessment of anal fistulae with and without H202 enhancement. METHODS: Sixty-one patients (37 males, aged 17-74 years) with anal fistulae, which were not simple low types, were evaluated by physical examination and 3D-EAUS with and without enhancement. Fistula classification was determined with each modality and compared to operative findings as the reference standard. RESULTS: The accuracy of 3D-EAUS was significantly higher than that of physical examination in detecting the primary tract (84.4% vs 68.7%, P = 0.037) and secondary extension (81.8% vs 62.1%, P = 0.01) and localizing the internal opening (84.2% vs 59.7%, P = 0.004). A contrast study with H202 detected several more fistula components including two primary suprasphincteric fistula tracks and one supralevator secondary extension, which were not detected on non-contrast study. However, there was no significant difference in accuracy between 3D-EAUS and H202- enhanced 3D-EAUS with respect to classification of the primary tract (84.4% vs 89.1%, P = 0.435) or secondary extension (81.8% vs 86.4%, P = 0.435) or localization of the internal opening (84.2% vs 89.5%, P = 0.406). CONCLUSION: 3D-EAUS was highly reliable in the diagnosis of an anal fistula. H2O2 enhancement was helpful at times and selective use in difficult cases may be economical and reliable.展开更多
Ice krill is the keystone species in the neritic ecosystem in the Southern Ocean, where it replaces the more oceanic Antarctic krill. It is essential to understand the variation of target strength (TS in dB re l m^2...Ice krill is the keystone species in the neritic ecosystem in the Southern Ocean, where it replaces the more oceanic Antarctic krill. It is essential to understand the variation of target strength (TS in dB re l m^2) with the different body size to accurately estimate ice krill stocks. However, there is comparatively little knowledge of the acoustic backscatter of ice krill. The TS of individual, formalin-preserved, tethered ice krill was measured in a freshwater test tank at 38, 120, and 200 kHz with a calibrated split-beam echo sounder system. Mean TS was obtained from 21 individual ice krill with a broad range of body lengths (L: 13-36 iron). The length (L, mm) to wet weight (W; mg) relationship for ice krill was 11/=0.001 21g^103~L35s (R2=0.96). The mean TS-to-length relationship were TS38kHz=-177.4+57log10(L), (R^2=0.86); TS120kHz= -129.9+31.561ogf0(L), (R2=0.87); and TS200kHz=-117.6+24.661ogre(L), (R2=0.84). Empirical estimates of the relationship between the TS and body length of ice krill were established at 38, 120, and 200 kHz and compared with predictions obtained from both the linear regression model of Greene et al. (1991) and the Stochastic Distorted Wave Born Approximation (SDWBA) model. This result might be applied to improve acoustic detection and density estimation of ice krill in the Southern Ocean. Further comparative studies are needed with in situ target strength including various body lengths of ice krill.展开更多
This study based on documents and materials, interview, experiment and data statistical analysis, as well as by the means of "Health Qigong.WuQinxi", and carries on a 4-month exercise intervention aiming at the univ...This study based on documents and materials, interview, experiment and data statistical analysis, as well as by the means of "Health Qigong.WuQinxi", and carries on a 4-month exercise intervention aiming at the university students, furthermore to have a comparison of their level scores on physical shape, physiological indicator, before and after the experiment. And we come to a conclusion through this 4-month exercise, when concerns to physical shape and physiological indicator: we can see a significant difference on WHR body mass index and vital capacity (p≤ 0.01); as well as waist circumference, pulse, systolic blood pressure, diastolic blood pressure, sit and reach, grip strength (p ≤ 0.05). So we note that long-term "Health Qignng .WuQinxi" practice can improve the physical health of the university students, and assess the students who failed to meet health standards physically, and fmally realize our hope promoting the comprehensive development of university students.展开更多
AIM: To evaluate the diagnostic values of serum autoan tibodies against matrix metalloproteinase-7 (MMP-7) in patients with esophageal squamous cell carcinoma (ESCC). METHODS: The MMP-7 cDNA was cloned from ESCC...AIM: To evaluate the diagnostic values of serum autoan tibodies against matrix metalloproteinase-7 (MMP-7) in patients with esophageal squamous cell carcinoma (ESCC). METHODS: The MMP-7 cDNA was cloned from ESCC tissues, and MMP-7 was expressed and purified from a prokaryotic system. MMP-7 autoanUbodies were then measured in sera from 50 patients with primary ESCC and 58 risk-matched controls, using a reverse capture enzyme-linked immunosorbent assay (ELISA) in which autoantibodies to MMP-7 bound to the purified MMP-7 proteins. In addition, MMP-7 autoantibody levels in sera from 38 gastric cancer patients and from control serum samples were also tested. RESULTS: The optimum conditions for recombinant MMP-7 protein expression were determined as 0.04 mmol/L Isopropyl-13-D-Thiogalactopyranoside (IPTG)induction at 37℃ for four hours. The levels of serum autoantibodies against MMP-7 were significantly higher in patients with ESCC than in the matched-control samples (OD450 = 1.69 ±0.08 vs OD450 = 1.55 ± 0.10, P 〈 0.001). The area under the receiver operating character- istic (ROC) curve was 0.87. The sensitivity and specificity for detection of ESCC were 78.0% and 81.0%, respectively, when the OD450 value was greater than 1.65. Although the levels of autoantibodies against MMP-7 were also significantly higher in patients with gastric cancer compared to control samples (OD450 = 1.62± 0.06 vs OD450 = 1.55±0.10, P 〈 0.001), the diagnostic accuracy was less significant than in ESCC patients. The area of ROC curve was 0.75, whereas the sensitivity and specificity were 60.5% and 71.7%, respectively, when the cut-off value of OD450 was set at 1.60. CONCLUSION: Serum autoantibody levels of MMP-7 may be a good diagnostic biomarker for esophageal squamous cell carcinoma,展开更多
基金Research for Intractable Disease of the Pancreas, Ministry of Health, Labor and Welfare of Japan
文摘Autoimmune pancreatitis (AIP) is a particular type of pancreatitis of presumed autoimmune etiology. Currently, AIP should be diagnosed based on combination of clinical, serological, morphological, and histopathological features. When diagnosing AIP, it is most important to differentiate it from pancreatic cancer. Diagnostic criteria for AIP, proposed by the Japan Pancreas Society in 2002 first in the world, were revised in 2006. The criteria are based on the minimum consensus of AIP and aim to avoid misdiagnosing pancreatic cancer as far as possible, but not for screening AIR The criteria consist of the following radiological, serological, and histopathological items: (1) radiological imaging showing narrowing of the main pancreatic duct and enlargement of the pancreas, which are characteristic of the disease; (2) laboratory data showing abnormally elevated levels of serum y-globulin, IgG or IgG4, or the presence of autoantibodies; (3) histopathological examination of the pancreas demonstrating marked fibrosis and prominent infiltration of lymphocytes and plasma cells, which is called lymphoplasmacytic sclerosing pancreatitis (LPSP). For a diagnosis of AIP, criterion 1 must be present, together with criterion 2 and/ or criterion 3. However, it is necessary to exclude malignant diseases such as pancreatic or biliary cancer.
基金Supported by In part by the Medical Research Fund of the National Hospital of Icelandthe Medical Research Fund of Wyeth, Iceland+3 种基金Actavis, IcelandAstraZeneca, Iceland GlaxoSmithKline, Icelandand the Icelandic College of Family Physicians
文摘AIM: To study if and how physicians use the irritable bowel syndrome (IBS) diagnostic criteria and to assess treatment strategies in IBS patients. METHODS: A questionnaire was sent to 191 physicians regarding IBS criteria, diagnostic methods and treatment. Furthermore, 94 patients who were diagnosed with IBS underwent telephone interview. RESULTS: A total of 80/191 (41.9%) physicians responded to the survey. Overall, 13 patients were diag-nosed monthly with IBS by specialists in gastroenterology (SGs) and 2.5 patients by general practitioners (GPs). All the SGs knew of the criteria to diagnose IBS, as did 46/70 (65.7%) GPs. Seventy-nine percent used the patient's history, 38% used a physical examination, and 38% exclusion of other diseases to diagnose IBS. Only 18/80 (22.5%) physicians used specific IBS criteria. Of the patients interviewed, 59/94 (62.8%) knew they had experienced IBS. Two out of five patients knew IBS and had seen a physician because of IBS symptoms. Half of those received a diagnosis of IBS. A total of 13% were satisfied with treatment. IBS affected daily activities in 43% of cases. CONCLUSION: Half of the patients with IBS who consulted a physician received a diagnosis. Awareness and knowledge of diagnostic criteria for IBS differ between SGs and GPs.
文摘Most complications after appendectomy occur within ten days; however, we report the unusual case of a suture granuloma 12 years after open appendectomy. The afebrile 75-year-old woman presented with a slightly painful palpable mass in the right lower abdomen. There was no nausea or vomiting and bowel movements were normal. She lost 10 kg during the 3 mo before presentation. The patient had undergone an appendectomy 12 years previously. Physical examination revealed a tender mass, 10 cm in diameter, under the appendectomy scar. The preoperative laboratory findings, tumor markers and plain abdominal radiographs were normal. Multi-slice computed tomography scanning showed an inhomo-genous abdominal mass with minimal vascularization in the right lower abdomen 8.6cm×8cm×9 cm in size which communicated with the abdominal wall. The abdominal wall was thickened, weak and bulging. The abdominal wall mass did not communicate with the cecum or the ascending colon. Complete excision of the abdominal wall mass was performed via median laparotomy. Histopathological examination revealed a granuloma with a central abscess. This case report demonstrates that a preoperative diagnosis of abdominal wall mass after open appendectomy warrants the use of a wide spectrum of diagnostic modalities and consequently different treatment options.
文摘In the 2013 release of the U.S. National Physical Education Standards the term "physically literate" replaced "physically educated". Un- fortunately, most discourse within the profession about the term physically literate occurred primarily after its adoption. While we agree with the spirit and intent of the term, we feel it is essential to discuss not only what has been potentially gained but also lost. In our paper, we illustrate the similarity of the terms physically educated and physically literate and essentially, from a definitional perspective, find little difference--but are these terms interchangeable? We provide a critical review of the standards and conclude that the change to physical literacy has produced a shift away from psychomotor outcomes to cognitive outcomes. Our concerns about this are many, but most importantly they are about the need to emphasize the "physical" in physical education (PE). It is our belief that the key to elevating the profession and maintaining and increasing support for PE is in its ability to promote and provide physical activity. Without physical activity and physical fitness as main outcomes, PE increases its vulnerability to extinction as a standard part of the U.S. K-12 education curriculum.
文摘Autoimmune hepatitis (AIH) is a progressive inflammatory liver disorder that is rare in children and adolescents. AIH has a broad clinical spectrum and a quick response to treatment with corticosteroids and immunosuppressive medication. The available diagnosis criteria have limitations and should be evaluated in pediatric populations. Recently, some studies reported that the 2008 simplified diagnostic criteria for AIH could be used in children with high sensibility and specificity. In addition, the authors reported that globulin and immunoglobulin G levels can be used interchangeably for diagnostic purposes. They also demonstrated that the 2008 simplified criteria fail in identifying patients with fulminant hepatic failure. Here, we discuss the limitations of the use of these criteria in pediatric patients and the requirement of more studies to improve the diagnosis of AIH in children.
文摘The similarities and differences of ASTM and China GB standard are studied in three aspects:measure instrument,terminology and applicable field.They are similar on the measuring apparatus and GB has less measurements,such as girth,length and width measurements than ASTM and it lack across chest width,back width,total crotch length and shoulder slope which are important measurements in pattern making.ASTM classifies its standards according to the customers' size,gender and age.So we think GB standard could make some modifications from these fields to satisfy the users.
文摘AIM: To evaluate the effectiveness of three-dimensional endoanal ultrasound (3D-EAUS) in the assessment of anal fistulae with and without H202 enhancement. METHODS: Sixty-one patients (37 males, aged 17-74 years) with anal fistulae, which were not simple low types, were evaluated by physical examination and 3D-EAUS with and without enhancement. Fistula classification was determined with each modality and compared to operative findings as the reference standard. RESULTS: The accuracy of 3D-EAUS was significantly higher than that of physical examination in detecting the primary tract (84.4% vs 68.7%, P = 0.037) and secondary extension (81.8% vs 62.1%, P = 0.01) and localizing the internal opening (84.2% vs 59.7%, P = 0.004). A contrast study with H202 detected several more fistula components including two primary suprasphincteric fistula tracks and one supralevator secondary extension, which were not detected on non-contrast study. However, there was no significant difference in accuracy between 3D-EAUS and H202- enhanced 3D-EAUS with respect to classification of the primary tract (84.4% vs 89.1%, P = 0.435) or secondary extension (81.8% vs 86.4%, P = 0.435) or localization of the internal opening (84.2% vs 89.5%, P = 0.406). CONCLUSION: 3D-EAUS was highly reliable in the diagnosis of an anal fistula. H2O2 enhancement was helpful at times and selective use in difficult cases may be economical and reliable.
基金Supported by the Korea Polar Research Institute(No.PP14020)the Korea Institute of Ocean Science and Technology(No.PN65250)
文摘Ice krill is the keystone species in the neritic ecosystem in the Southern Ocean, where it replaces the more oceanic Antarctic krill. It is essential to understand the variation of target strength (TS in dB re l m^2) with the different body size to accurately estimate ice krill stocks. However, there is comparatively little knowledge of the acoustic backscatter of ice krill. The TS of individual, formalin-preserved, tethered ice krill was measured in a freshwater test tank at 38, 120, and 200 kHz with a calibrated split-beam echo sounder system. Mean TS was obtained from 21 individual ice krill with a broad range of body lengths (L: 13-36 iron). The length (L, mm) to wet weight (W; mg) relationship for ice krill was 11/=0.001 21g^103~L35s (R2=0.96). The mean TS-to-length relationship were TS38kHz=-177.4+57log10(L), (R^2=0.86); TS120kHz= -129.9+31.561ogf0(L), (R2=0.87); and TS200kHz=-117.6+24.661ogre(L), (R2=0.84). Empirical estimates of the relationship between the TS and body length of ice krill were established at 38, 120, and 200 kHz and compared with predictions obtained from both the linear regression model of Greene et al. (1991) and the Stochastic Distorted Wave Born Approximation (SDWBA) model. This result might be applied to improve acoustic detection and density estimation of ice krill in the Southern Ocean. Further comparative studies are needed with in situ target strength including various body lengths of ice krill.
文摘This study based on documents and materials, interview, experiment and data statistical analysis, as well as by the means of "Health Qigong.WuQinxi", and carries on a 4-month exercise intervention aiming at the university students, furthermore to have a comparison of their level scores on physical shape, physiological indicator, before and after the experiment. And we come to a conclusion through this 4-month exercise, when concerns to physical shape and physiological indicator: we can see a significant difference on WHR body mass index and vital capacity (p≤ 0.01); as well as waist circumference, pulse, systolic blood pressure, diastolic blood pressure, sit and reach, grip strength (p ≤ 0.05). So we note that long-term "Health Qignng .WuQinxi" practice can improve the physical health of the university students, and assess the students who failed to meet health standards physically, and fmally realize our hope promoting the comprehensive development of university students.
基金Supported by Science and Technology Projects of Hebei Province, #10396107DNIH Grant CA137570 (Zhong L)
文摘AIM: To evaluate the diagnostic values of serum autoan tibodies against matrix metalloproteinase-7 (MMP-7) in patients with esophageal squamous cell carcinoma (ESCC). METHODS: The MMP-7 cDNA was cloned from ESCC tissues, and MMP-7 was expressed and purified from a prokaryotic system. MMP-7 autoanUbodies were then measured in sera from 50 patients with primary ESCC and 58 risk-matched controls, using a reverse capture enzyme-linked immunosorbent assay (ELISA) in which autoantibodies to MMP-7 bound to the purified MMP-7 proteins. In addition, MMP-7 autoantibody levels in sera from 38 gastric cancer patients and from control serum samples were also tested. RESULTS: The optimum conditions for recombinant MMP-7 protein expression were determined as 0.04 mmol/L Isopropyl-13-D-Thiogalactopyranoside (IPTG)induction at 37℃ for four hours. The levels of serum autoantibodies against MMP-7 were significantly higher in patients with ESCC than in the matched-control samples (OD450 = 1.69 ±0.08 vs OD450 = 1.55 ± 0.10, P 〈 0.001). The area under the receiver operating character- istic (ROC) curve was 0.87. The sensitivity and specificity for detection of ESCC were 78.0% and 81.0%, respectively, when the OD450 value was greater than 1.65. Although the levels of autoantibodies against MMP-7 were also significantly higher in patients with gastric cancer compared to control samples (OD450 = 1.62± 0.06 vs OD450 = 1.55±0.10, P 〈 0.001), the diagnostic accuracy was less significant than in ESCC patients. The area of ROC curve was 0.75, whereas the sensitivity and specificity were 60.5% and 71.7%, respectively, when the cut-off value of OD450 was set at 1.60. CONCLUSION: Serum autoantibody levels of MMP-7 may be a good diagnostic biomarker for esophageal squamous cell carcinoma,