高校工会在学校向教学研究型转型过程中的作用

本文以上海工程技术大学工会工作为例,分析在向教学研究型转型过程中高校工会面临的问题,并提出相关建议,旨在对高校工会加强转型期建设和开展各种工会活动有所助益。

Reversal of the phenotype by K-ras^(val12) silencing mediated by adenovirus-delivered siRNA in human pancreatic cancer cell line Panc-1

AIM: To investigate the in vitro antitumor effect of adenovirus-mediated small interfering RNAs (siRNAs) on pancreatic cancer and the associated mechanism. METHODS: A 63-nucleotide (nt) oligonucleotide encoding K-rasval12 and specific siRNA were introduced into pSilencer 3.1-H1, then the H1-RNA promoter and siRNA coding insert were subcloned into pAdTrack to get plasmid pAdTrackH1-Avasval12. After homologous recombination in bacteria and transfections of such plasmids into a mammalian packaging cell line 293, siRNA expressing adenovirus Adh1-K-rasval12 was obtained. Stable suppression of K-rasval12 was detected by Northern blot and Western blot. Apoptosis in Panc-1 cells was detected by flow cytometry. RESULTS: We obtained adenovirus AdHl-K-rasval12 carrying the pSilencer 3.1-H1 cassette, which could mediate gene silencing. Through siRNA targeted K-rasval12, the oncogenic phenotype of cancer cells was reversed. Flow cytometry showed that apoptotic index of Panc-1 cells was significantly higher in the AdH1-K-rasval12-treatment group (18.70% at 72 h post-infection, 49.55% at 96 h post-infection) compared to the control groups (3.47%, 3.98% at 72 and 96 h post-infection of AdH1-empty, respectively; 4.21%, 3.78% at 72 and 96 h post-infection of AdHl-p53, respectively) (P<0.05). CONCLUSION: These results demonstrate that adenoviral vectors can be used to mediate RNA interference (RNAi) to induce persistent loss of functional phenotypes. In gene therapy, the selective down-regulation of only the mutant version of a gene allows for highly specific effects on tumor cells, while leaving the normal cells untouched. In addition, the apoptosis of pancreatic cancer cell line Panc-1 can be induced after AdH1-K-rasval12 infection. This kind of adenovirus based on RNAi might be a promising vector for cancer therapy.

国有企业经济与社会发展浅探

党的十七届五中全会强调必须加强党的执政能力建设和先进性建设,不断提高党领导经济社会发展能力和水平。伴随着国资国企改革的进程,当前都会直接面临转型升级的任务。如何进一步提高思想政治工作者的重要地位,如何切实加强和改进思想政治工作,如何充分发挥他们的作用,可以说这是摆在面前的一项重大课题。

Effect of Energy Transfer on UV Spectra of “H-shaped” Azobenzene Derivatives

A series of “H-shaped” organic dimers （azobenzene derivatives） exhibit linear absorption red shift compared with their corresponding monomers experimentally. Dipolar interaction model is not appropriate for the azobenzene derivatives due to the small distance between two “D-π-A” chains. Energy transfer model is suggested for explanation of the absorption red shift. Two necessary conditions for energy transfer were verified. In addition, bi-exponential florescence-delay behavior of the dimer as well as Bella＇s quantum chemistry calculation shows evidence of energy transfer.

Division and integration tendency of college students＇ political socialization

the political socialization of college students is the purpose of the individual to accept political culture in the historical, social, cultural and the specific interaction, formation of political attitude, the practice process of shaping the political people. Our country is in the period of social transition, this period of transformation of political, economic and cultural construction of the China different from traditional political culture atmosphere, in the impact of the global political factors, college students＇ political psychology, political attitude and political behavior has undergone a series of changes. These changes impact on the existing college students＇ political socialization outcomes, so that students show the political and social highlights issues in the process of social transformation. In this case,we should only study the college students＇ optimization approach of political socialization carefully, improve the level of Chinese college students＇ political socialization, to ensure China＇ s social transition in a stable order smoothly, develop socialist political requirements of qualified university students, so as to make the socialism prosperous.

Monte Carlo Study of Planar Rotator Model with Weak Dzyaloshinsky-Moriya Interaction

With the help of an improvement Monte Carlo method, the Berezinskii-Kosterlitz-Thouless phase transition arising in two-dimensional planar rotator model with weak Dzyaloshinsky-Moriya （DM） interaction is investigated. The effects of the DM interaction on specific heat, susceptibility, and magnetization are simulated. The critical temperature of transitions is determined by the so-called Binder cumulant and the susceptibility of finite-size scaling. We find that the chiral Z2 symmetry reduced by the DM interactions plays an important role in a two-dimensional XY spin system, typically, the critical temperature is sensitive to weak DM spin couplings.

A Review on Regeneration in Cowpea （Vigna unguiculata L. Walp）

Vigna unguiculata L. Walp is a recalcitrant plant in terms of in vitro cell, tissue and organ differentiation, which makes it difficult to apply tissue-culture dependant approaches for obtaining stable genetic transformation in cowpea. Despite this, sporadic efforts have been made to develop regeneration systems in cowpea during the past 40 years. This review presents the considerable progress on cowpea regeneration （organogenesis and embryogenesis） and especially focuses on the regeneration mode of organogenesis, including highlights of the effect of genotypes, explants, medium and plant hormones used in tissue culture. The existing problems and the future research directions were also discussed.

媒介融合视角下图书编辑转型策略分析

在信息时代来临之际,信息技术被应用于各行各业中。信息技术的普遍应用,推动媒介间相互关联,促进社会和经济发展。图书是我们民族文化精神的标志,历来,我国对文化则更为重视。传统图书已不再适应当前社会需要,改进运作模式很有必要。传统图书出版业要想获得持续、稳定的进步和发展,必须不断进行传统模式的变革。充分利用媒介资源,强化图书与互联网的连接。传统图书编辑在当前社会中受到了一些挑战,极大增加了传统图书出版竞争压力。所以,为能促进图书编辑工作更好地开展和进步,文章就图书编辑的转型问题展开论述与分析,在媒介融合视角下,促进图书编辑转型的深入开展。

Long time evolution of a spin interacting with a spin bath in arbitrary magnetic field

We introduce a completely different method to calculate the evolution of a spin interacting with a sufficient large spin bath,especially suitable for treating the central spin model in a quantum dot(QD).With only an approximation on the envelope of central spin,the symmetry can be exploited to reduce a huge Hilbert space which cannot be calculated with computers to many small ones which can be solved exactly.This method can be used to calculate spin-bath evolution for a spin bath containing many(say,1000)spins,without a perturbative limit such as strong magnetic field condition,and works for long-time regime with sufficient accuracy.As the spin-bath evolution can be calculated for a wide range of time and magnetic field,an optimal dynamic of spin flip-flop can be found,and more sophisticated approaches to achieve extremely high polarization of nuclear spins in a QD could be developed.

Critical Properties of a Generalized Planar Rotator Model

The critical properties of the planar rotator model with chiral Dzyaloshinsky-Moriya interaction are analyzed using a hybrid Monte Carlo method.Simulations on different lattices conform an observation that there is an XY-like Berezinskii-Kosterlitz-Thouless (BKT) phase transition in this model.The ground state and some thermodynamics properties are also discussed.

The companion properties of SNe Ia from the single degenerate model

Although Type Ia supernovae (SNe Ia) play very important roles in many astrophysical fields, the exact nature of the progenitors of SNe Ia is still unclear. At present, the single degenerate (SD) model is a very likely one. Following the comprehensive SD model developed by Meng & Yang (2010), we show the properties of SNe Ia companions at the moment of the supernova explosion. The results may provide help in searching for companion stars in supernova remnants. We compared our results with the companion candidate Tycho G of Tycho's supernova and found that integral properties of the star (mass, space velocity, radius, luminosity and effective temperature) are all consistent with those predicted from our SD model with the exception of the rotational velocity. If Tycho G was the companion star of Tycho's supernova, an interaction between supernova ejecta and the rotational companion might be a key factor to solve the confliction, and then it could be encouraged to do a detailed numerical simulation about the interaction.