目的系统评价预防性放疗能否降低恶性胸膜间皮瘤(MPM)有创操作通道转移(PTMs)发生率。方法检索PubMed、Cochrane Library、Web of Science、Embase数据库,收集MPM有创操作通道进行预防性放疗的相关研究,由两位评价员独立筛选文献、提取...目的系统评价预防性放疗能否降低恶性胸膜间皮瘤(MPM)有创操作通道转移(PTMs)发生率。方法检索PubMed、Cochrane Library、Web of Science、Embase数据库,收集MPM有创操作通道进行预防性放疗的相关研究,由两位评价员独立筛选文献、提取资料并评价纳入研究的方法学质量后,采用RevMan5.3软件进行Meta分析。结果共纳入7项研究,包括698例患者。Meta分析结果显示,预防性放疗不能降低所有MPM患者PTMs的发生率(OR=0.48,95%CI:0.22~1.07,P=0.07)。而进行亚组分析后发现预防性放疗能有效减少进行大口径操作的MPM患者(OR=0.39,95%CI:0.18~0.84,P=0.02),或上皮型MPM患者(OR=0.21,95%CI:0.11~0.69,P=0.006)医源性PTMs的发生。结论预防性放疗能有效预防进行开胸手术、胸腔镜、留置胸壁引流管等大口径操作或病理类型为上皮型MPM患者医源性PTMs的发生。展开更多
The high degree of reversibility of heat integrated distillation column(HIDiC) has been thermodynamically interpreted by the entropy method. In this paper, a heat transfer model and a more universal method were propos...The high degree of reversibility of heat integrated distillation column(HIDiC) has been thermodynamically interpreted by the entropy method. In this paper, a heat transfer model and a more universal method were proposed, through which the overall heat transfer coefficient at different height of column under different operating conditions could be obtained before the experiment. Then the separation of a binary ethanol-water system was carried out experimentally as a case study to verify the heat transfer model and the aforementioned calculation method. The close results between the calculation, the simulation, and the experiments suggested that the proposed model and the calculation method in this paper were accurate and applicable. Meanwhile, it was demonstrated that the HIDiC shows obvious effect of reducing entropy increase and improving thermodynamic efficiency as compared to conventional distillation column.展开更多
The study herein investigated the effectiveness of simultaneous use of ozone and hydrogen peroxide(O_3/H_2O_2 process) to degrade o-phenylenediamine(o-PDA) in a simulated wastewater. A rotor–stator reactor(RSR) was e...The study herein investigated the effectiveness of simultaneous use of ozone and hydrogen peroxide(O_3/H_2O_2 process) to degrade o-phenylenediamine(o-PDA) in a simulated wastewater. A rotor–stator reactor(RSR) was employed to create a high-gravity environment in order to enhance ozone-liquid mass transfer rate and possibly improve the degradation rate of o-PDA. The degradation efficiency of o-PDA(η) as well as the overall gas-phase volumetric mass transfer coefficient(KGa) were determined under different operating conditions of H_2O_2 concentration, initial o-PDA concentration, temperature of reaction, initial p H and rotation speed of RSR in attempt to establish the optimal conditions. Chemical oxygen demand reduction rate(rCOD) of wastewater treated at a particular set of conditions was also analyzed. Additionally, the intermediate products of degradation were identified using a gas chromatography-mass spectrometer(GC/MS) to further evaluate the extent of o-PDA degradation as well as establish its possible degradation pathway. Results were validated by comparison with those of sole use of ozone(O_3 process), and it was noted that η, KGa and rCODachieved by O_3/H_2O_2 process was 24.4%,31.6% and 25.2% respectively higher than those of O_3 process, indicating that H_2O_2 can greatly enhance ozonation of o-PDA. This work further demonstrates that an RSR can significantly intensify ozone-liquid mass transfer rate and thus provides a feasible intensification means for the ozonation of o-PDA as well as other recalcitrant organics.展开更多
In this paper, a V-cycle multigrid method is presented for a Hermite rectangular element. By defining proper mesh-dependent inner product and transfer operator, we obtain its convergence property and the uniform conve...In this paper, a V-cycle multigrid method is presented for a Hermite rectangular element. By defining proper mesh-dependent inner product and transfer operator, we obtain its convergence property and the uniform convergence rate independent of mesh size and level are established.展开更多
A new castor wheel mechanism for omni-directional mobile platform is presented. A motion of translation is transformed into a rotation to steer the wheel with the help of a helical path fits into a translation joint a...A new castor wheel mechanism for omni-directional mobile platform is presented. A motion of translation is transformed into a rotation to steer the wheel with the help of a helical path fits into a translation joint and three rollers whose axes are connected to the driving shaft of the wheel. When the path moves in translation it acts on the rollers for steering. The path-roller friction transmission, the wheel kinematics and the maneuverability have been analyzed.展开更多
This paper gives the knotted picture of the unknown quantum state in the process of quantum teleportation and the surgical knotted operations of the unitary operators operated on the teleported quantum state.
OBJECTIVES: To investigate telomerase activity in esophageal squamous cell carcinoma (SCC) and its preneoplasia lesions, and to study the relationships between telomerase activity and cancer differentiation, cancer in...OBJECTIVES: To investigate telomerase activity in esophageal squamous cell carcinoma (SCC) and its preneoplasia lesions, and to study the relationships between telomerase activity and cancer differentiation, cancer invasiveness, and lymphatic metastasis. METHODS: Telomerase activity in esophageal SCC tissues, adjacent dysplasia tissues and normal epithelia from the surgical edge were assessed by microdissection-TRAP (telomeric repeat amplification protocol)-silver staining assay. RESULTS: Telomerase activity was detected in 37 (82.2%) of 45 esophageal tumors, 23 (79.3%) of 29 dysplasias, and 2 (5%) of 40 normal epithelia. There was a significant difference in activity between dysplasia and normal epithelium, as well as between tumor and normal epithelium. Twenty-six (92.9%) of 28 tumors with lymphatic metastasis had detectable telomerase activity compared to 11 (64.7%) of 17 non-lymphatic metastasis tumors. These relationships were statistically significant (P展开更多
文摘目的系统评价预防性放疗能否降低恶性胸膜间皮瘤(MPM)有创操作通道转移(PTMs)发生率。方法检索PubMed、Cochrane Library、Web of Science、Embase数据库,收集MPM有创操作通道进行预防性放疗的相关研究,由两位评价员独立筛选文献、提取资料并评价纳入研究的方法学质量后,采用RevMan5.3软件进行Meta分析。结果共纳入7项研究,包括698例患者。Meta分析结果显示,预防性放疗不能降低所有MPM患者PTMs的发生率(OR=0.48,95%CI:0.22~1.07,P=0.07)。而进行亚组分析后发现预防性放疗能有效减少进行大口径操作的MPM患者(OR=0.39,95%CI:0.18~0.84,P=0.02),或上皮型MPM患者(OR=0.21,95%CI:0.11~0.69,P=0.006)医源性PTMs的发生。结论预防性放疗能有效预防进行开胸手术、胸腔镜、留置胸壁引流管等大口径操作或病理类型为上皮型MPM患者医源性PTMs的发生。
基金supported by the National Key Research and Development Program of China(2017YFB0602500)the Foundation for High Level Talents of Hebei (A2017002032).
文摘The high degree of reversibility of heat integrated distillation column(HIDiC) has been thermodynamically interpreted by the entropy method. In this paper, a heat transfer model and a more universal method were proposed, through which the overall heat transfer coefficient at different height of column under different operating conditions could be obtained before the experiment. Then the separation of a binary ethanol-water system was carried out experimentally as a case study to verify the heat transfer model and the aforementioned calculation method. The close results between the calculation, the simulation, and the experiments suggested that the proposed model and the calculation method in this paper were accurate and applicable. Meanwhile, it was demonstrated that the HIDiC shows obvious effect of reducing entropy increase and improving thermodynamic efficiency as compared to conventional distillation column.
基金Supported by the National Natural Science Foundation of China(21276013,21676008)Specialized Research Fund for the Doctoral Program of Higher Education of China(20130010110001)
文摘The study herein investigated the effectiveness of simultaneous use of ozone and hydrogen peroxide(O_3/H_2O_2 process) to degrade o-phenylenediamine(o-PDA) in a simulated wastewater. A rotor–stator reactor(RSR) was employed to create a high-gravity environment in order to enhance ozone-liquid mass transfer rate and possibly improve the degradation rate of o-PDA. The degradation efficiency of o-PDA(η) as well as the overall gas-phase volumetric mass transfer coefficient(KGa) were determined under different operating conditions of H_2O_2 concentration, initial o-PDA concentration, temperature of reaction, initial p H and rotation speed of RSR in attempt to establish the optimal conditions. Chemical oxygen demand reduction rate(rCOD) of wastewater treated at a particular set of conditions was also analyzed. Additionally, the intermediate products of degradation were identified using a gas chromatography-mass spectrometer(GC/MS) to further evaluate the extent of o-PDA degradation as well as establish its possible degradation pathway. Results were validated by comparison with those of sole use of ozone(O_3 process), and it was noted that η, KGa and rCODachieved by O_3/H_2O_2 process was 24.4%,31.6% and 25.2% respectively higher than those of O_3 process, indicating that H_2O_2 can greatly enhance ozonation of o-PDA. This work further demonstrates that an RSR can significantly intensify ozone-liquid mass transfer rate and thus provides a feasible intensification means for the ozonation of o-PDA as well as other recalcitrant organics.
基金Supported by NSF of China(10971203)Supported by the NSF of the education Department of Henan Province (2009A110017)
文摘In this paper, a V-cycle multigrid method is presented for a Hermite rectangular element. By defining proper mesh-dependent inner product and transfer operator, we obtain its convergence property and the uniform convergence rate independent of mesh size and level are established.
文摘A new castor wheel mechanism for omni-directional mobile platform is presented. A motion of translation is transformed into a rotation to steer the wheel with the help of a helical path fits into a translation joint and three rollers whose axes are connected to the driving shaft of the wheel. When the path moves in translation it acts on the rollers for steering. The path-roller friction transmission, the wheel kinematics and the maneuverability have been analyzed.
文摘This paper gives the knotted picture of the unknown quantum state in the process of quantum teleportation and the surgical knotted operations of the unitary operators operated on the teleported quantum state.
文摘OBJECTIVES: To investigate telomerase activity in esophageal squamous cell carcinoma (SCC) and its preneoplasia lesions, and to study the relationships between telomerase activity and cancer differentiation, cancer invasiveness, and lymphatic metastasis. METHODS: Telomerase activity in esophageal SCC tissues, adjacent dysplasia tissues and normal epithelia from the surgical edge were assessed by microdissection-TRAP (telomeric repeat amplification protocol)-silver staining assay. RESULTS: Telomerase activity was detected in 37 (82.2%) of 45 esophageal tumors, 23 (79.3%) of 29 dysplasias, and 2 (5%) of 40 normal epithelia. There was a significant difference in activity between dysplasia and normal epithelium, as well as between tumor and normal epithelium. Twenty-six (92.9%) of 28 tumors with lymphatic metastasis had detectable telomerase activity compared to 11 (64.7%) of 17 non-lymphatic metastasis tumors. These relationships were statistically significant (P
