目的:研究转轮运动对小鼠吗啡条件性位置偏爱(conditioned place preference,CPP)的建立、消退及重建的影响。方法:每次吗啡CPP训练之后,均将动物置于特制的带有转轮的饲养笼内6 h;在CPP测试之后,动物每天在训练箱中自由穿梭,进行CPP消...目的:研究转轮运动对小鼠吗啡条件性位置偏爱(conditioned place preference,CPP)的建立、消退及重建的影响。方法:每次吗啡CPP训练之后,均将动物置于特制的带有转轮的饲养笼内6 h;在CPP测试之后,动物每天在训练箱中自由穿梭,进行CPP消退训练;待CPP消退之后,皮下注射(sc)10 mg.kg-1吗啡点燃。结果:非转轮运动组和转轮运动组的小鼠经过吗啡CPP训练后,在伴药箱的时间较训练前均显著增加(P<0.001),但两组间没有明显差异;两组小鼠的吗啡CPP消退过程也没有明显差异(P>0.05)。sc吗啡点燃后,非转轮运动组CPP能够重建,而转轮运动组CPP未能重建;结论:转轮运动对吗啡CPP的建立及消退均没有影响,但可以抑制吗啡CPP的重建。展开更多
The application of fine blanking to the manufacturing of helical gears directly from a strip has been restricted due to the traditional linear cutting stroke of the punch and die.In this work,rotational fine blanking ...The application of fine blanking to the manufacturing of helical gears directly from a strip has been restricted due to the traditional linear cutting stroke of the punch and die.In this work,rotational fine blanking which combined the linear and rotational motion of punch and counterpunch was applied for the forming of helical gears.A three-dimensional(3D) rigid-plastic finite element model was developed on the DEFORM-3D platform.By finite element simulation and analysis,the influences of key parameters on the punch load and cut surface were investigated.It is shown that: 1) with increasing the counterforce or helical angle,the punch load and the depth of die roll increase; 2) with increasing blank holder force,the punch load increases while the depth of die roll decreases; 3) V-ring indenter facilitates an improvement in the quality.The results of this research reveal the deformation mechanism of rotational fine blanking of helical gears,and provide valuable guidelines for further experimental studies.展开更多
Machines are often subjected to periodic loads, related both to the characteristics of the payload or to the kinematic chains used for motion generation, such as linkages or cam follower mechanisms. The load fluctuati...Machines are often subjected to periodic loads, related both to the characteristics of the payload or to the kinematic chains used for motion generation, such as linkages or cam follower mechanisms. The load fluctuation can cause several inconveniences to the proper functioning of the machines, like shaking forces and moments, vibrations, severe speed fluctuations. Speed fluctuations are a main source of concern since, generally, mechanisms design and optimization is performed considering a constant main shaft speed and a departure from ideal behavior gets worse increasing machine speed. The simpler approach used to mitigate this fact consists in adopting a large flywheel and/or a massive motor, even to drive small loads. More sophisticated procedures add appropriate balancer mechanisms to the machine. This paper, starting from a review of the available literature, presents a theoretical framework to the problem of input torque balancing and defines a methodology for the synthesis of balancing mechanisms.展开更多
The counter-rotating type hydroelectric unit, which is composed of the axial flow type tandem runners and the peculiar generator with double rotational armatures, has been proposed. In the unit, the front and the rear...The counter-rotating type hydroelectric unit, which is composed of the axial flow type tandem runners and the peculiar generator with double rotational armatures, has been proposed. In the unit, the front and the rear runners counter-drive the inner and the outer armatures of the generator, respectively. Besides, the flow direction at the rear runner outlet must coincide with the direction at the front runner inlet, because the angular momentum change through the rear runner must coincides with that through the front runner. In this paper, the tandem runners work at on-cam conditions in keeping the induced frequency constant, to provide the hydroelectric unit for the power grid system. The output and the hydraulic efficiency are affected by the adjusting angles of the front and the rear blades. Both optimum angles giving the maximum output or efficiency were presented at the various discharge/head circumstances, accompanying with the turbine performances.展开更多
A roller rack pinion(RRP)system,which consists of a rack-bar and a cam pinion,transforms a rotation motion into linear motion.The rack-bar has a series of roller train and meshes with the cam pinion.First,the exact to...A roller rack pinion(RRP)system,which consists of a rack-bar and a cam pinion,transforms a rotation motion into linear motion.The rack-bar has a series of roller train and meshes with the cam pinion.First,the exact tooth profile of the cam pinion and the non-undercut condition to satisfy the required performance have been proposed with the introduction of the profile shift coefficient.Then,the load stress factors are investigated under the variation of the shape design parameters to predict the gear surface fatigue limit which is strongly related to the gear noise and vibration at the contact patch.The results show that the pitting life can be extended significantly with the increase of the profile shift coefficient.展开更多
文摘目的:研究转轮运动对小鼠吗啡条件性位置偏爱(conditioned place preference,CPP)的建立、消退及重建的影响。方法:每次吗啡CPP训练之后,均将动物置于特制的带有转轮的饲养笼内6 h;在CPP测试之后,动物每天在训练箱中自由穿梭,进行CPP消退训练;待CPP消退之后,皮下注射(sc)10 mg.kg-1吗啡点燃。结果:非转轮运动组和转轮运动组的小鼠经过吗啡CPP训练后,在伴药箱的时间较训练前均显著增加(P<0.001),但两组间没有明显差异;两组小鼠的吗啡CPP消退过程也没有明显差异(P>0.05)。sc吗啡点燃后,非转轮运动组CPP能够重建,而转轮运动组CPP未能重建;结论:转轮运动对吗啡CPP的建立及消退均没有影响,但可以抑制吗啡CPP的重建。
基金Project(51105287)supported by the National Natural Science Foundation of ChinaProject(2011-P05)supported by the State Key Laboratory of Materials Processing and Die&Mould Technology,Huazhong University of Science and Technology,ChinaProject(2011-IV-009)supported by the Fundamental Research Funds for the Central Universities,China
文摘The application of fine blanking to the manufacturing of helical gears directly from a strip has been restricted due to the traditional linear cutting stroke of the punch and die.In this work,rotational fine blanking which combined the linear and rotational motion of punch and counterpunch was applied for the forming of helical gears.A three-dimensional(3D) rigid-plastic finite element model was developed on the DEFORM-3D platform.By finite element simulation and analysis,the influences of key parameters on the punch load and cut surface were investigated.It is shown that: 1) with increasing the counterforce or helical angle,the punch load and the depth of die roll increase; 2) with increasing blank holder force,the punch load increases while the depth of die roll decreases; 3) V-ring indenter facilitates an improvement in the quality.The results of this research reveal the deformation mechanism of rotational fine blanking of helical gears,and provide valuable guidelines for further experimental studies.
文摘Machines are often subjected to periodic loads, related both to the characteristics of the payload or to the kinematic chains used for motion generation, such as linkages or cam follower mechanisms. The load fluctuation can cause several inconveniences to the proper functioning of the machines, like shaking forces and moments, vibrations, severe speed fluctuations. Speed fluctuations are a main source of concern since, generally, mechanisms design and optimization is performed considering a constant main shaft speed and a departure from ideal behavior gets worse increasing machine speed. The simpler approach used to mitigate this fact consists in adopting a large flywheel and/or a massive motor, even to drive small loads. More sophisticated procedures add appropriate balancer mechanisms to the machine. This paper, starting from a review of the available literature, presents a theoretical framework to the problem of input torque balancing and defines a methodology for the synthesis of balancing mechanisms.
文摘The counter-rotating type hydroelectric unit, which is composed of the axial flow type tandem runners and the peculiar generator with double rotational armatures, has been proposed. In the unit, the front and the rear runners counter-drive the inner and the outer armatures of the generator, respectively. Besides, the flow direction at the rear runner outlet must coincide with the direction at the front runner inlet, because the angular momentum change through the rear runner must coincides with that through the front runner. In this paper, the tandem runners work at on-cam conditions in keeping the induced frequency constant, to provide the hydroelectric unit for the power grid system. The output and the hydraulic efficiency are affected by the adjusting angles of the front and the rear blades. Both optimum angles giving the maximum output or efficiency were presented at the various discharge/head circumstances, accompanying with the turbine performances.
基金Research financially supported by Changwon National University in 2011-2012,Korea
文摘A roller rack pinion(RRP)system,which consists of a rack-bar and a cam pinion,transforms a rotation motion into linear motion.The rack-bar has a series of roller train and meshes with the cam pinion.First,the exact tooth profile of the cam pinion and the non-undercut condition to satisfy the required performance have been proposed with the introduction of the profile shift coefficient.Then,the load stress factors are investigated under the variation of the shape design parameters to predict the gear surface fatigue limit which is strongly related to the gear noise and vibration at the contact patch.The results show that the pitting life can be extended significantly with the increase of the profile shift coefficient.
