竹叶多酚软胶囊内容物的制备

目的以竹叶多酚提取物为原料,制备软胶囊内容物。方法以亚麻籽油为分散剂,蜂蜡为助悬剂,大豆磷脂为湿润剂,采用均匀性、切断性、流动性、粘稠度、沉降时间及沉降比作为评价指标,通过单因素实验探究竹叶多酚软胶囊内容物的最佳配比工艺。结果较优内容物配比为:竹叶多酚-V_E混合粉末与亚麻籽油质量比为1:2.5~1:3,蜂蜡占亚麻籽油质量分数的2%~4%,大豆磷脂占亚麻籽油质量分数的0%~1%。结论制丸温度25℃左右,内容物均匀性良好,且具有一定的流动性和粘稠度,符合软胶囊生产灌装的要求。

中国文化软实力浅析

"软实力"是一种财富,中国文化软实力以中华民族优秀的传统文化为首要资源和重要基础,以和谐文化为主题,社会主义核心价值体系是其意识形态的本质体现。同时,文化产业是中国文化软实力不可或缺的"硬性"特质。商业运作对提升中国文化软实力有重要作用。

“互联网+”背景下服装品牌IP开发与运营研究

基于当下互联网思维重构的新业态、新生态的转向趋势,以及IP从泛娱乐形态快速渗透到新商业生态的生存背景,以逻辑分析的研究方法厘清IP内容运营类型特征及内容运营方式。运用调查研究法对典型案例分析讨论,旨在探究服装品牌IP开发与内容运营策略,并创新提出隶属内容运营范畴的"软内容"这一概念。研究得出"经营高效社群""输出软内容""内容衍生产品""产品衍生内容"四大服装品牌IP内容运营策略,有助于服装品牌找到全新的商业生存方式,为服装行业可持续、纵深感发展提供启示。

Digital Rights Management：Model,Technology and Application

with rapid achievement of current information technology and computing ability and applications,much more digital content such as films,cartoons,design drawings,office documents and software source codes are produced in daily work,however to protect the content being copying,shared or deliberately stolen by inside or outside,digital rights management(DRM) became more and more important for digital content protection.In this paper,we studied various DRM model,technology and application,and first proposed DRM Security Infrastructure(DSI),in which we defined encryption,hash,signature algorithm,watermarking algorithms,authentication,usage control,trusted counter,conditional trace,secure payment,and based on the DSI we then proposed a whole classification approach and architecture of all kinds of DRMs,in which we proposed 6 typical classes of copyrights and content protection DRMs architecture:(1) Software-oriented DRM,(2) e Book-oriented DRM,(3) Video-oriented DRM,(4) Image-Oriented DRM(5) Unstructured data oriented DRM,(6) Text-oriented DRM.Based on the above DSI,we then proposed a dynamic DRM model selection method for various DRM application,which can be adapted dynamically for different technology of different applications,which can provide awhole solution for variant DRM development in a rapid and customized mode.The proposed DRM method,technology and application in this paper provided a common,flexible and extendable solution for variant DRM scenes,and can support rapid and customized development.Moreover,we proposed an opinion that the future life will enter into a new era that the content usage and consumption will not again adopt DRM technology rather than with law,liberty and morality.

大鼠口服不同形式茯苓三萜类成分提取物后有效成分的药代动力学分析

目的:建立UPLC-Q-TOF/MS测定大鼠口服茯苓三萜类成分提取物粉末及软胶囊内容物后土莫酸及去氢土莫酸的血浆药物浓度,研究这2个成分的体内药代动力学过程,比较二者在粉末与软胶囊内容物中的药代动力学差异。方法:血浆样品采用乙酸乙酯提取,以甘草次酸为内标物,流动相0.1%甲酸水溶液(A)-0.1%甲酸乙腈溶液(B)梯度洗脱(0~3 min,50%~70%B;3~3.5 min,70%~100%B;3.5~4.5 min,100%B),正离子模式,毛细管电压3 k V,锥孔电压40 V,离子源温度120℃,脱溶剂温度500℃,脱溶剂气流速800 L·h^(-1)。结果:软胶囊内容物中土莫酸和去氢土莫酸药峰浓度(Cmax)及药时曲线下面积(AUC0-t)均大于粉末。软胶囊内容物中土莫酸的达峰时间(Tmax)大于粉末,而去氢土莫酸的Tmax则小于粉末,结论:植物油的加入促进了土莫酸和去氢土莫酸的吸收,推测由于土莫酸和去氢土莫酸的化学结构不同,剂型变化后会引起吸收速率的改变。