Aims:To describe the impact of age related macular degeneration(AMD)on quality of life and explore the association with vision,health,and demographic variables.Methods:Adult participants diagnosed with AMD and with im...Aims:To describe the impact of age related macular degeneration(AMD)on quality of life and explore the association with vision,health,and demographic variables.Methods:Adult participants diagnosed with AMD and with impaired vision(visual acuity < 6/12)were assessed with the Impact of Vision Impairment(IVI)questionnaire.Participants rated the extent that vision restricted participation in activities affecting quality of life and completed the Short Form General Health Survey(SF-12)and a sociodemographic questionnaire.Results:The mean age of the 106 participants(66% female)was 83.6 years(range 64-98).One quarter had mild vision impairment,(VA < 6/12-6/18)and 75% had moderate or severely impaired vision.Participants reported from at least "a little" concern on 23 of the 32 IVI items including reading,emotional health,mobility,and participation in relevant activities.Those with mild and moderate vision impairment were similarly affected but significantly different from those with severe vision loss(p< 0.05).Distance vision was associated with IVI scores but not age,sex,or duration of vision loss.Conclusion:AMD affects many quality of life related activities and not just those related to reading.Referral to low vision care services should be considered for people with mild vision loss and worse.展开更多
Background: The relationship between granuloma annularae (GA) and diabetes mellitus (DM) is controversial. Objective: To investigate the relationship between multiple lesions of GA and carbohydrate metabolism in child...Background: The relationship between granuloma annularae (GA) and diabetes mellitus (DM) is controversial. Objective: To investigate the relationship between multiple lesions of GA and carbohydrate metabolism in children. Subjects and methods: Fifteen children (seven boys, eight girls, mean age 4.8 years) with five or more lesions of GA were evaluated. A personal and family history of DM or other autoimmune diseases was obtained and the glycaemic and insulin response during an oral glucose tolerance test (OGTT) was determined. Thirteen children with a negative personal and family history of DM served as controls for the OGTT and 100 other children as ‘ clinical controls’ . Results: At the 30- min sampling of the OGTT the mean insulin values were comparable in GA children and controls (P=0.1), while the mean glucose values were significantly higher in GA children than in controls (P=0.005). All other insulin values during the OGTT were significantly lower in GA children than in controls, while all other glucose values were comparable in GA children and controls with all indices applied. Eleven out of 15 GA children had a positive family history of DM (73.3% vs. 16% of the clinical controls; P < 0.0001). Conclusion: Multiple lesions of GA in children are associated with significantly lower serum insulin values than in controls and mildly impaired glucose tolerance.展开更多
文摘Aims:To describe the impact of age related macular degeneration(AMD)on quality of life and explore the association with vision,health,and demographic variables.Methods:Adult participants diagnosed with AMD and with impaired vision(visual acuity < 6/12)were assessed with the Impact of Vision Impairment(IVI)questionnaire.Participants rated the extent that vision restricted participation in activities affecting quality of life and completed the Short Form General Health Survey(SF-12)and a sociodemographic questionnaire.Results:The mean age of the 106 participants(66% female)was 83.6 years(range 64-98).One quarter had mild vision impairment,(VA < 6/12-6/18)and 75% had moderate or severely impaired vision.Participants reported from at least "a little" concern on 23 of the 32 IVI items including reading,emotional health,mobility,and participation in relevant activities.Those with mild and moderate vision impairment were similarly affected but significantly different from those with severe vision loss(p< 0.05).Distance vision was associated with IVI scores but not age,sex,or duration of vision loss.Conclusion:AMD affects many quality of life related activities and not just those related to reading.Referral to low vision care services should be considered for people with mild vision loss and worse.
文摘Background: The relationship between granuloma annularae (GA) and diabetes mellitus (DM) is controversial. Objective: To investigate the relationship between multiple lesions of GA and carbohydrate metabolism in children. Subjects and methods: Fifteen children (seven boys, eight girls, mean age 4.8 years) with five or more lesions of GA were evaluated. A personal and family history of DM or other autoimmune diseases was obtained and the glycaemic and insulin response during an oral glucose tolerance test (OGTT) was determined. Thirteen children with a negative personal and family history of DM served as controls for the OGTT and 100 other children as ‘ clinical controls’ . Results: At the 30- min sampling of the OGTT the mean insulin values were comparable in GA children and controls (P=0.1), while the mean glucose values were significantly higher in GA children than in controls (P=0.005). All other insulin values during the OGTT were significantly lower in GA children than in controls, while all other glucose values were comparable in GA children and controls with all indices applied. Eleven out of 15 GA children had a positive family history of DM (73.3% vs. 16% of the clinical controls; P < 0.0001). Conclusion: Multiple lesions of GA in children are associated with significantly lower serum insulin values than in controls and mildly impaired glucose tolerance.
