The purpose of this study was to examine the impact of macro social factors （states, religion, region, Arab spring, terrorism, unrest （Shoe index）, democracy, corruption （GPI）, Human development （HDI）, low self...The purpose of this study was to examine the impact of macro social factors （states, religion, region, Arab spring, terrorism, unrest （Shoe index）, democracy, corruption （GPI）, Human development （HDI）, low self-control, life stress events （LSE）, youth unemployment, religiosity, feeling （fear and anger）, youth unemployment and total unemployment） on Arab youth＇s radicalization. A sample of 6,730 Arab youth age 15-24 years was selected from Kuwait, UAE, KSA, Oman, Qatar, Bahrain, Jordan, Tunisia, Libya, Morocco, Lebanon, Egypt, Gaza and Palestine and Syrian refuges in Jordan. A questionnaire of 43 items to measure radicalization was developed based on the literature review. A construct validity of the scale was estimated by calculating the correlation between radicalization scale and Low self-control scale and found a positive significant relationship （0.680, a = 0.000）, a sign of validity of the scale. A Reliability of the scale is strong and was estimated by Cronbach＇s alpha and was 0.947. An average of 46.6% of the participants was categorized as radicals with standard deviation of 12. Macro social factors explained 64% of the variance on radicalization. It has a significant impact on radicalization （F = 807.6, a = 0.000）. Each single variable has a significant impact. The analysis revealed three groups of macro determinants of youth radicalization were identified： （1） Geographic factors： state, region, and Arab spring; （2） Social factors： religion, religiously, feelings, LSE and LSC; （3） Human security： unrest, terrorism, democracy, corruption, human development, youth unemployment and employment rate. To alleviate the consequences of radicalization, prevention policies should take in account youth concerns as partners and victims of radicalization. Policies need to focus on radicalization pull and push factors on micro-meso-macro level.展开更多
Nuclear accidents and terrorism present a serious threat for mass casualty.Accidental or intended radiation exposure leads to radiation-induced gastrointestinal(GI)syndrome.However,currently there are no approved medi...Nuclear accidents and terrorism present a serious threat for mass casualty.Accidental or intended radiation exposure leads to radiation-induced gastrointestinal(GI)syndrome.However,currently there are no approved medical countermeasures for GI syndrome.Thus,developing novel treatments for GI syndrome is urgent.Mesenchymal stem cells(MSCs)derived from bone marrow are a subset of multipotent adult somatic stem cells that have the ability to undergo self-renewal,proliferation and pluripotent differentiation.MSCs have advantages over other stem cells;they can be easily isolated from patients or donors,readily expanded ex vivo,and they possess reparative and immunomodulatory properties.Moreover,MSCs have been shown to be powerful tools in gene therapy and can be effectively transduced with vectors containing therapeutic genes.Therefore,the therapeutic potential of MSCs has been brought into the spotlight for the clinical treatment of GI syndrome.In this review,we discuss the possible role of MSCs in radiation-induced GI syndrome.展开更多
文摘The purpose of this study was to examine the impact of macro social factors （states, religion, region, Arab spring, terrorism, unrest （Shoe index）, democracy, corruption （GPI）, Human development （HDI）, low self-control, life stress events （LSE）, youth unemployment, religiosity, feeling （fear and anger）, youth unemployment and total unemployment） on Arab youth＇s radicalization. A sample of 6,730 Arab youth age 15-24 years was selected from Kuwait, UAE, KSA, Oman, Qatar, Bahrain, Jordan, Tunisia, Libya, Morocco, Lebanon, Egypt, Gaza and Palestine and Syrian refuges in Jordan. A questionnaire of 43 items to measure radicalization was developed based on the literature review. A construct validity of the scale was estimated by calculating the correlation between radicalization scale and Low self-control scale and found a positive significant relationship （0.680, a = 0.000）, a sign of validity of the scale. A Reliability of the scale is strong and was estimated by Cronbach＇s alpha and was 0.947. An average of 46.6% of the participants was categorized as radicals with standard deviation of 12. Macro social factors explained 64% of the variance on radicalization. It has a significant impact on radicalization （F = 807.6, a = 0.000）. Each single variable has a significant impact. The analysis revealed three groups of macro determinants of youth radicalization were identified： （1） Geographic factors： state, region, and Arab spring; （2） Social factors： religion, religiously, feelings, LSE and LSC; （3） Human security： unrest, terrorism, democracy, corruption, human development, youth unemployment and employment rate. To alleviate the consequences of radicalization, prevention policies should take in account youth concerns as partners and victims of radicalization. Policies need to focus on radicalization pull and push factors on micro-meso-macro level.
文摘Nuclear accidents and terrorism present a serious threat for mass casualty.Accidental or intended radiation exposure leads to radiation-induced gastrointestinal(GI)syndrome.However,currently there are no approved medical countermeasures for GI syndrome.Thus,developing novel treatments for GI syndrome is urgent.Mesenchymal stem cells(MSCs)derived from bone marrow are a subset of multipotent adult somatic stem cells that have the ability to undergo self-renewal,proliferation and pluripotent differentiation.MSCs have advantages over other stem cells;they can be easily isolated from patients or donors,readily expanded ex vivo,and they possess reparative and immunomodulatory properties.Moreover,MSCs have been shown to be powerful tools in gene therapy and can be effectively transduced with vectors containing therapeutic genes.Therefore,the therapeutic potential of MSCs has been brought into the spotlight for the clinical treatment of GI syndrome.In this review,we discuss the possible role of MSCs in radiation-induced GI syndrome.
