肝纤维化病证结合模型的研制

目的:制备客观、公认的肝纤维化病证结合模型。方法:分别设立正常对照组、单纯肝纤维化组、肝纤维化肝郁脾虚证组和气虚血瘀证组,各模型组先用CCl4注射法复制肝硬化疾病模型,然后肝郁脾虚证组附加夹尾和大黄灌胃法、气虚血瘀证组附加游泳疲劳法,并以相应药物干预以反证模型制备的成功。对各组大鼠进行一般情况和肝组织病理观察。结果:各模型组均出现一般情况较差;病理检查示不同程度肝纤维化表现;肝郁脾虚证组和气虚血瘀证组均出现相应的中医证候表现。结论:按本实验方法复制的肝纤维化病证结合模型既符合肝纤维化病理特征,又能体现中医不同证候特点。

Dialectical thinking in engineering management

Modem engineering management activities have all become more complex, being far beyond the economic and technological areas, due to their growing grand scales, increasingly complex structures and integrated systems. Therefore, we need focus our attention on engineering management activities by resorting to dialectical thinking and take full account of them based on the height of the new era. This paper described and analyzed engineering management activities from the following 5 aspects ： the cyclic promotion between engineering management theory and engineering management practice, the in-depth integration of engineering management concepts with engineering management methods, the coordinated harmonization of engineering management system with engineering management details, the mutual promotion between engineering management standardization and engineering management innovation, the common enhancement between engineering management team and engineering management system.